PTM - dbPAF Gene Name UniProt ID Position Type Species SRC; SRC1 P12931 104 S Homo sapiens(Human) SRC; SRC1 P12931 12 S Homo sapiens(Human) SRC; SRC1 P12931 17 S Homo sapiens(Human) SRC; SRC1 P12931 182 T Homo sapiens(Human) SRC; SRC1 P12931 183 T Homo sapiens(Human) SRC; SRC1 P12931 187 Y Homo sapiens(Human) SRC; SRC1 P12931 216 Y Homo sapiens(Human) SRC; SRC1 P12931 246 T Homo sapiens(Human) SRC; SRC1 P12931 250 T Homo sapiens(Human) SRC; SRC1 P12931 255 T Homo sapiens(Human) SRC; SRC1 P12931 304 T Homo sapiens(Human) SRC; SRC1 P12931 306 S Homo sapiens(Human) SRC; SRC1 P12931 338 Y Homo sapiens(Human) SRC; SRC1 P12931 348 S Homo sapiens(Human) SRC; SRC1 P12931 35 S Homo sapiens(Human) SRC; SRC1 P12931 37 T Homo sapiens(Human) SRC; SRC1 P12931 385 Y Homo sapiens(Human) SRC; SRC1 P12931 39 S Homo sapiens(Human) SRC; SRC1 P12931 419 Y Homo sapiens(Human) SRC; SRC1 P12931 420 T Homo sapiens(Human) SRC; SRC1 P12931 43 S Homo sapiens(Human) SRC; SRC1 P12931 439 Y Homo sapiens(Human) SRC; SRC1 P12931 51 S Homo sapiens(Human) SRC; SRC1 P12931 511 T Homo sapiens(Human) SRC; SRC1 P12931 522 Y Homo sapiens(Human) SRC; SRC1 P12931 525 S Homo sapiens(Human) SRC; SRC1 P12931 526 T Homo sapiens(Human) SRC; SRC1 P12931 530 Y Homo sapiens(Human) SRC; SRC1 P12931 69 S Homo sapiens(Human) SRC; SRC1 P12931 70 S Homo sapiens(Human) SRC; SRC1 P12931 72 T Homo sapiens(Human) SRC; SRC1 P12931 74 T Homo sapiens(Human) SRC; SRC1 P12931 75 S Homo sapiens(Human) SRC; SRC1 P12931 93 Y Homo sapiens(Human) SRC; SRC1 P12931 97 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA P12931 K62-ac Acetylation APAAAEPkLFGGFNs P12931 S12-p Phosphorylation KSKPKDAsQRRRsLE P12931 S17-p Phosphorylation DAsQRRRsLEPAENV P12931 S35-p Phosphorylation GGGAFPAsQtPsKPA P12931 T37-p Phosphorylation GAFPAsQtPsKPAsA P12931 S39-p Phosphorylation FPAsQtPsKPAsAdG P12931 S43-p Phosphorylation QtPsKPAsAdGHRGP P12931 S51-p Phosphorylation AdGHRGPsAAFAPAA P12931 S69-p Phosphorylation kLFGGFNssDtVtsP P12931 S70-p Phosphorylation LFGGFNssDtVtsPQ P12931 T72-p Phosphorylation GGFNssDtVtsPQRA P12931 T74-p Phosphorylation FNssDtVtsPQRAGP P12931 S75-p Phosphorylation NssDtVtsPQRAGPL P12931 Y93-p Phosphorylation VTTFVALyDYEsRTE P12931 S97-p Phosphorylation VALyDYEsRTETDLs P12931 S104-p Phosphorylation sRTETDLsFKKGERL P12931 T182-p Phosphorylation FLVRESEttKGAyCL P12931 T183-p Phosphorylation LVRESEttKGAyCLS P12931 Y187-p Phosphorylation SEttKGAyCLSVSDF P12931 Y216-p Phosphorylation KLDSGGFyITSRTQF P12931 T246-p Phosphorylation GLCHRLTtVCPtSKP P12931 T250-p Phosphorylation RLTtVCPtSKPQtQG P12931 T255-p Phosphorylation CPtSKPQtQGLAKDA P12931 S269-p Phosphorylation AWEIPREsLRLEVKL P12931 T304-p Phosphorylation IKTLKPGtMsPEAFL P12931 S306-p Phosphorylation TLKPGtMsPEAFLQE P12931 Y338-p Phosphorylation VVSEEPIyIVTEYMS P12931 S348-p Phosphorylation TEYMSKGsLLDFLKG P12931 Y385-p Phosphorylation AYVERMNyVHRDLRA P12931 Y419-p Phosphorylation RLIEDNEytARQGAK P12931 T420-p Phosphorylation LIEDNEytARQGAKF P12931 Y439-p Phosphorylation TAPEAALyGRFTIKS P12931 Y522-p Phosphorylation LQAFLEDyFTstEPQ P12931 S525-p Phosphorylation FLEDyFTstEPQyQP P12931 T526-p Phosphorylation LEDyFTstEPQyQPG P12931 Y530-p Phosphorylation FTstEPQyQPGENL_ P12931 K430-ub Ubiquitination QGAKFPIkWTAPEAA

PTM - dbPTM UniProt ID Position Code Type Resources References P12931 17 S Phosphorylation Swiss-Prot 1010711 17192257;18088087;19369195 P12931 35 S Phosphorylation Swiss-Prot 1010711 19369195 P12931 69 S Phosphorylation Swiss-Prot 1010711 17192257;19369195 P12931 74 T Phosphorylation Swiss-Prot 1010711 18088087;19369195 P12931 75 S Phosphorylation Swiss-Prot 1010711 17192257;18691976;19369195;21442427 P12931 419 Y Phosphorylation Swiss-Prot 1010711 6273838;17192257;18088087;18936167 P12931 439 Y Phosphorylation Swiss-Prot 1010711 18083107 P12931 511 T Phosphorylation Swiss-Prot 1010711 19369195 P12931 522 Y Phosphorylation Swiss-Prot 1010711 19369195 P12931 530 Y Phosphorylation Swiss-Prot 1010711 7525268;19369195;19534553 P12931 2 G Myristoylation Swiss-Prot 1010711 - P12931 12 S Phosphorylation PhosphoELM.10011 2136766 P12931 69 S Phosphorylation PhosphoELM.10011 17192257 P12931 97 S Phosphorylation PhosphoELM.10011 1713455 P12931 75 S Phosphorylation PhosphoELM.10011 17192257;10544291;10544291 P12931 17 S Phosphorylation PhosphoELM.10011 18088087;17192257;17081983;11804588 P12931 74 T Phosphorylation PhosphoELM.10011 18088087 P12931 439 Y Phosphorylation PhosphoELM.10011 18083107 P12931 530 Y Phosphorylation PhosphoELM.10011 12387813;3103926;12468645 P12931 216 Y Phosphorylation PhosphoELM.10011 12753909 P12931 338 Y Phosphorylation PhosphoELM.10011 7578094 P12931 419 Y Phosphorylation PhosphoELM.10011 17192257;17081983;11278940;6273838;15489898;11804588;7578094 P12931 45 D Caspase Phosphositeplus.1010730 18722006 P12931 12 S Phosphorylation Phosphositeplus.1010730 18069897;2136766 P12931 17 S Phosphorylation Phosphositeplus.1010730 11804588;12221082;12606547;15546918;17192257;18088087;19369195;19664994;20166139;20363803;21406692;21659604 P12931 69 S Phosphorylation Phosphositeplus.1010730 19369195 P12931 70 S Phosphorylation Phosphositeplus.1010730 17192257 P12931 75 S Phosphorylation Phosphositeplus.1010730 10544291;17192257;18691976;19369195;19415658;19690332;21442427;7488156;9271228 P12931 97 S Phosphorylation Phosphositeplus.1010730 1713455 P12931 420 T Phosphorylation Phosphositeplus.1010730 17192257;22115753 P12931 72 T Phosphorylation Phosphositeplus.1010730 17192257 P12931 74 T Phosphorylation Phosphositeplus.1010730 18088087;19415658 P12931 187 Y Phosphorylation Phosphositeplus.1010730 18083107;18180459;21253578 P12931 216 Y Phosphorylation Phosphositeplus.1010730 11304462;12753909;14760089;15301956;21253578 P12931 338 Y Phosphorylation Phosphositeplus.1010730 7578094 P12931 419 Y Phosphorylation Phosphositeplus.1010730 10958798;11278940;11304462;11600431;11756413;11804588;11940607;11983694;12014987;12052863;12084011;12223349;12368297;12473651;12606547;12748308;12753909;12771140;12869650;12909616;12921535;14576154;14660586;14661060;14720123;14761895;14963038;15034138;15143062;15301956;15485877;15489898;15564375;15604220;15623525;15695828;15708852;15713897;15777801;15811957;15817476;15866871;15899872;15958584;15994317;16002410;16002577;16037379;16126727;16291744;16317717;16331263;16410281;16461772;16491114;16843263;16844778;16862179;16920701;16920985;16966330;17012367;17016520;17045208;17045821;17062641;17088251;17148760;17190831;17192257;17215324;17234774;17283152;17317726;17318191;17360941;17389395;17449913;17570831;17575268;17646646;17653080;17828307;17967179;18056483;18056643;18063582;18069897;18070987;18083107;18088087;18176934;18180459;18211905;18283331;18320059;18326860;18362147;18451158;18454177;18460189;18498747;18578522;18669648;18691976;18707149;18776048;18922892;18936167;19014372;19033444;19050761;19118003;19205871;19223540;19369195;19534553;19543320;19574224;19605366;19658100;19664994;19682241;19690332;19888469;19923279;20010870;20053726;20058876;20068231;20072652;20090780;20129247;20145126;20190765;20211239;20371672;20383201;20385765;20388777;20433855;20450893;20473329;20498373;20501847;20543098;20615878;20628053;20736484;20837138;20926745;21049007;21059620;21123455;21253578;21278788;2136766;21383697;21394647;21399647;21399663;21403953;21406692;21423210;21442427;21447384;21454698;21478903;21478906;21525036;21659604;21725358;21726627;21785464;21798346;21810913;21878628;21900501;21994943;22056988;22115753;22169477;22322096;7578094;9271228 P12931 439 Y Phosphorylation Phosphositeplus.1010730 18083107;18180459;19369195;19534553;19605366;20736484;21253578;21403953;21447384 P12931 522 Y Phosphorylation Phosphositeplus.1010730 22238675 P12931 530 Y Phosphorylation Phosphositeplus.1010730 11035005;11676480;11940607;12052863;12221082;12473651;12505989;12529448;12604776;12606547;12753909;12771140;12921535;14504278;14506284;14665621;15143062;15301956;15489898;15777801;15831486;15866871;15899872;16002410;16291744;16410281;16491114;16790421;17045208;17062641;17234774;17449913;17575268;17828307;17974954;18083107;18180459;18211905;18454177;18498747;18936167;19223540;19369195;19534553;20211239;20385765;20501847;20615878;20736484;21059620;21253578;2136766;21383697;21399647;21442427;21798346;22169477;22322096;7578094;9171348;9655255 P12931 419 Y Dephosphorylation HPRD 9.0 9261115,11007774 P12931 530 Y Dephosphorylation HPRD 9.0 12468645,8647855,9261115,11007774 P12931 419 Y Dephosphorylation HPRD 9.0 12554790,15588985 P12931 419 Y Dephosphorylation HPRD 9.0 15696169 P12931 338 Y Dephosphorylation HPRD 9.0 9261115 P12931 419 Y Dephosphorylation HPRD 9.0 9261115 P12931 530 Y Dephosphorylation HPRD 9.0 12468645,8647855,9261115 P12931 530 Y Dephosphorylation HPRD 9.0 12468645,8647855,9261115,10698938,10787408,7691597,15588985 P12931 530 Y Dephosphorylation HPRD 9.0 15845350,15522235 P12931 2 G Myristoylation HPRD 9.0 3917576,7527558 P12931 97 S Phosphorylation HPRD 9.0 1713455 P12931 306 S Phosphorylation HPRD 9.0 20068231 P12931 74 T Phosphorylation HPRD 9.0 19415658,18088087 P12931 216 Y Phosphorylation HPRD 9.0 12753909 P12931 75 S Phosphorylation (CDK5) HPRD 9.0 10544291,19415658,18691976 P12931 17 S Phosphorylation (PRKACA) HPRD 9.0 15546918,18088087,19651622,19664994,20166139 P12931 12 S Phosphorylation (PRKCA) HPRD 9.0 2996780 P12931 530 Y Phosphorylation (CSK) HPRD 9.0 12387813,7678701,9208935 P12931 530 Y Phosphorylation (CSK) HPRD 9.0 12468645,12387813,7678701,9208935 P12931 530 Y Phosphorylation (FGR) HPRD 9.0 12468645,12387813,7678701,9208935 P12931 419 Y Phosphorylation (SRC) HPRD 9.0 9988270,17389395,19664994,17016520 P12931 419 Y Phosphorylation (SRC) HPRD 9.0 9988270,14661060,15466214,17389395,19664994,17016520 P12931 17 S Phosphorylation SysPTM 1.1 18088087 P12931 39 S Phosphorylation SysPTM 1.1 17081983 P12931 75 S Phosphorylation SysPTM 1.1 18691976 P12931 525 S Phosphorylation SysPTM 1.1 17081983 P12931 37 T Phosphorylation SysPTM 1.1 17081983 P12931 74 T Phosphorylation SysPTM 1.1 18088087 P12931 419 Y Phosphorylation SysPTM 1.1 18088087

PTM - HPRD Symbol Position Code Type References SRC 12 S Phosphorylation 2996780 SRC 17 S Phosphorylation 15546918,18088087,19651622,19664994,20166139 SRC 2 G Myristoylation 3917576,7527558 SRC 216 Y Phosphorylation 12753909 SRC 306 S Phosphorylation 20068231 SRC 338 Y Dephosphorylation 9261115 SRC 419 Y Dephosphorylation 12554790,15588985 SRC 419 Y Dephosphorylation 15696169 SRC 419 Y Dephosphorylation 9261115 SRC 419 Y Dephosphorylation 9261115,11007774 SRC 419 Y Phosphorylation 9988270,14661060,15466214,17389395,19664994,17016520 SRC 419 Y Phosphorylation 9988270,17389395,19664994,17016520 SRC 530 Y Dephosphorylation 12468645,8647855,9261115 SRC 530 Y Dephosphorylation 12468645,8647855,9261115,10698938,10787408,7691597,15588985 SRC 530 Y Dephosphorylation 12468645,8647855,9261115,11007774 SRC 530 Y Dephosphorylation 15845350,15522235 SRC 530 Y Phosphorylation 12387813,7678701,9208935 SRC 530 Y Phosphorylation 12468645,12387813,7678701,9208935 SRC 74 T Phosphorylation 19415658,18088087 SRC 75 S Phosphorylation 10544291,19415658,18691976 SRC 97 S Phosphorylation 1713455

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type P12931 216 Y 12753909 SRC LTP Phosphorylation P12931 69 S 17192257 HTP Phosphorylation P12931 97 S 1713455 LTP Phosphorylation P12931 74 T 18088087 HTP Phosphorylation P12931 439 Y 18083107 HTP Phosphorylation P12931 75 S 17192257 HTP Phosphorylation P12931 75 S 10544291 CDK_group LTP Phosphorylation P12931 75 S 10544291 CDK5 LTP Phosphorylation P12931 338 Y 7578094 SRC LTP Phosphorylation P12931 12 S 2136766 LTP Phosphorylation P12931 419 Y 17192257 HTP Phosphorylation P12931 419 Y 17081983 HTP Phosphorylation P12931 419 Y 11278940 LTP Phosphorylation P12931 419 Y 6273838 LTP Phosphorylation P12931 419 Y 15489898 SRC LTP Phosphorylation P12931 419 Y 11804588 SRC LTP Phosphorylation P12931 419 Y 7578094 SRC LTP Phosphorylation P12931 17 S 18088087 HTP Phosphorylation P12931 17 S 17192257 HTP Phosphorylation P12931 17 S 17081983 HTP Phosphorylation P12931 17 S 11804588 PKA_group LTP Phosphorylation P12931 530 Y 12387813 LTP Phosphorylation P12931 530 Y 3103926 LTP Phosphorylation P12931 530 Y 12468645 Csk LTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs P12931 17 Phosphoserine 18088087;19369195;23186163;24275569 P12931 35 Phosphoserine 7929427 P12931 69 Phosphoserine 7929427 P12931 74 Phosphothreonine 7929427 P12931 75 Phosphoserine; by CDK5 23186163;21442427 P12931 419 Phosphotyrosine; by autocatalysis 14661060;18936167;26936507;6273838 P12931 439 Phosphotyrosine 7929427 P12931 511 Phosphothreonine 7929427 P12931 522 Phosphotyrosine 7929427 P12931 530 Phosphotyrosine; by CSK 19369195;26936507;7525268

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type SRC IPI00328867 S 17 ASQRRRpSLEPAEN phosphorylation SRC IPI00328867 S 69 LFGGFNpSSDTVTS phosphorylation SRC IPI00328867 S 75 SSDTVTpSPQRAGP phosphorylation SRC IPI00328867 Y 425 LIEDNEpYTARQGA phosphorylation SRC IPI00328867 Y 445 APEAALpYGRFTIK phosphorylation SRC IPI00328867 Y 536 TSTEPQpYQPGENL phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 6714 112592 - K Ubiquitination 21911421 6714 112592 - K Ubiquitination 20584982 6714 112592 - K Ubiquitination 21139048 6714 112592 - K Ubiquitination 22447928 6714 112592 - K Ubiquitination 17936276 6714 112592 - K Ubiquitination 21890473 6714 112592 - K Ubiquitination 14661060 6714 112592 - K Ubiquitination 25147182

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID SRC Homo sapiens (Human) 430 "430,GAKFPIKWTAPEA" 430:21890473 SRC Homo sapiens (Human) 430 "430,GAKFPIKWTAPEA" 430:21890473 SRC Homo sapiens (Human) 430 "430,GAKFPIKWTAPEA" 430:21890473 SRC Homo sapiens (Human) 436 "436,GAKFPIKWTAPEA" 436:21890473