PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus RAB40C RAB40C 23638186 biogrid exp G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G TOE1 RAB40C 16169070 hprd,i2d,mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G PSD RAB40C 16169070 hprd,mint,intact exp G P G G G G P GP G G G G GP G G RAB40B RAB40C 26186194 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G RABGGTB RAB40C 26186194 biogrid exp G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G DCUN1D1 RAB40C 21145461 biogrid exp G G G GP G P P G P P P GP G GP G G G GP GP P GP G ANKRD27 RAB40C 25661869 biogrid exp, ortho G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G TCEB1 RAB40C 15601820, 25402006 innatedb,biogrid,intact exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CUL5 RAB40C 15601820,21145461, 25402006 innatedb,biogrid,intact exp, pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G RAB40C RNF7 15601820, 25402006 biogrid,intact exp, pred G G G G GP GP G G GP G GP G G G G GP GP G GP G G G G G GP G GP GP G TCEB2 RAB40C 15601820, 25402006 innatedb,biogrid,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RAD23B RAB40C ortho G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G CCDC64B RAB40C ortho G G G GP GP GP GP G GP G GP G G GP GP GP G G G GP GP GP P G RIN2 RAB40C 16082366 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP P G RASGEF1C RAB40C 16082366 pred G P GP P P G P P P GP GP P P P GP RAB40C RPH3A 16082366 pred G G G G G GP G G G G G G GP G G G GP G G G G G G G G G G LRR1 RAB40C 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G VHL RAB40C 25402006 pred G G G G G G G G G G GP G GP G G G G G P G G G G G G G G GP G BCAR3 RAB40C 16082366 pred G G G P GP G GP GP G GP G GP G G GP GP G P G G G G GP GP G GP GP G RAB40C RGL1 16082366 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G RAPGEF3 RAB40C 16082366 pred G G P GP G GP GP G GP GP G G P GP G GP G G G GP P G GP P G MED8 RAB40C 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G RAB40C IKBKG 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RASGRP1 RAB40C 16082366 pred G G G G G G G G G G G G G G G G G G G SOS2 RAB40C 16082366 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G SPSB1 RAB40C 25402006 pred G G G G GP GP G GP G G GP G GP G G G GP G GP G G G G GP G GP GP G SH2D3C RAB40C 16082366 pred G G G G GP G G GP G G GP G G G G G G G G G G G G G G GP GP G RIN1 RAB40C 16082366 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G SOCS2 RAB40C 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G SYTL4 RAB40C 16082366 pred G G G G GP GP G G GP G GP G GP G G P GP G GP G G G G GP G GP GP G RAB40C RAPGEFL1 16082366 pred G G GP P G P P GP GP P P P P SOCS3 RAB40C 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G RALGPS2 RAB40C 16082366 pred G G G GP P G P GP GP G P G G GP P G P G P GP G GP GP RAPGEF1 RAB40C 16082366 pred G G G G GP GP G G GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G SOCS5 RAB40C 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G SPSB4 RAB40C 25402006 pred G RASGRF2 RAB40C 16082366 pred G G G G GP GP G GP GP G GP GP G G GP GP G GP G G G GP GP G GP GP G RASGEF1B RAB40C 16082366 pred P P P G P P P P P P RALGDS RAB40C 16082366 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G RGL2 RAB40C 16082366 pred G G G G G GP G GP GP G GP G G G G GP GP G GP G G G G GP GP G GP GP G SOS1 RAB40C 16082366 pred G G G G GP G G GP GP G GP G GP G G GP G G GP G G G G GP GP G GP G G LRRC41 RAB40C 25402006 pred G G G G GP G G GP GP G GP G GP G G GP G G GP G G G G GP GP G GP GP G SOCS1 RAB40C 25402006 pred G G P P GP GP GP G GP G G GP P G GP G G G P GP G GP GP G ASB2 RAB40C 25402006 pred P P G GP P P G P P G G G G P G RGL4 RAB40C 16082366 pred G G P P P P G P P P P G P SOCS4 RAB40C 25402006 pred G G G G GP GP G G GP G GP G GP G G GP GP G G G G G G GP GP G GP GP G RASGRP2 RAB40C 16082366 pred G G G G GP GP GP GP G GP G GP G G GP GP P G G GP GP G GP P G RAB40C FEM1B 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G GP GP G GP GP G RAB40C SPSB2 25402006 pred G G G G G GP G G P G GP G GP G GP GP G GP G G G G GP G GP GP G RBX1 RAB40C 25402006 pred G G G G G GP G GP G G G G GP G G G GP G GP G G G G G G G G GP G CUL2 RAB40C 25402006 pred G G G G G GP G G GP G GP G GP G G G GP G GP G G G G G G G GP GP G COPS6 RAB40C 25402006 pred G G G G GP GP G GP GP G GP G GP G G GP GP G GP G G G G G GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A5PKW4 Q96S21 two hybrid pooling approach 16169070 physical association X 2 Q96S21 anti tag coimmunoprecipitation 15601820 association C 5 Q96S21 anti tag coimmunoprecipitation 15601820 direct interaction C 5 Q96S21 Q96GM8 two hybrid pooling approach 16169070 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B PSD RAB40C MI:0018(two hybrid)|MI:0018(two hybrid) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint) MINT_63408|MINT_34452 bait|bait prey|prey DCUN1D1 RAB40C MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_206033 bait prey RAB40C PSD MI:0007(anti tag coimmunoprecipitation)|MI:0492(in vitro) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (intact)|MI:0468(hprd) UniProt_157102|HPRD_29798 prey|- bait|- TCEB2 RAB40C MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 15601820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_164457|UniProt_80329|UniProt_164446|UniProt_80340|BIOGRID_250336 prey|prey|prey|prey|prey bait|bait|bait|bait|bait TCEB1 RAB40C MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 15601820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_164457|UniProt_80329|UniProt_164446|UniProt_80340|BIOGRID_250337 prey|prey|prey|prey|prey bait|bait|bait|bait|bait CUL5 RAB40C MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15601820,21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid)|(biogrid) UniProt_164457|UniProt_80329|UniProt_164446|UniProt_80340|BIOGRID_203566|BIOGRID_250334 prey|prey|prey|prey|bait|prey bait|bait|bait|bait|prey|bait TOE1 RAB40C MI:0492(in vitro)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation) 16169070 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0471(mint)|MI:0471(mint)|(intact) HPRD_29921|MINT_34795|MINT_63765|UniProt_157213 -|bait|bait|bait -|prey|prey|prey RAB40C RNF7 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 15601820 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0407(direct interaction)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_164457|UniProt_80329|UniProt_164446|UniProt_80340|BIOGRID_250335 bait|bait|bait|bait|bait prey|prey|prey|prey|prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q96S21 P53611 RAB40C RABGGTB 0.126 26186194 Q9UBF6 Q96S21 RNF7 RAB40C 0.376 15601820 Q96S21 Q15370 RAB40C TCEB2 0.376 15601820 Q96S21 Q15369 RAB40C TCEB1 0.376 15601820 Q96S21 Q93034 RAB40C CUL5 0.454 15601820,21145461 Q96S21 Q96GG9 RAB40C DCUN1D1 0.126 21145461 Q96S21 Q96NW4 RAB40C ANKRD27 0.309 25661869 Q96S21 A5PKW4 RAB40C PSD 0.126 16169070 Q9DBG5 Q96S21 PLIN3 RAB40C 0.309 23638186 Q96S21 Q8CHW5 RAB40C CCDC64B 0.126 20360680 Q96S21 Q96S21 RAB40C RAB40C 0.332 23638186 Q96S21 Q96GM8 RAB40C TOE1 0.126 16169070 Q96S21 Q12829 RAB40C RAB40B 0.126 26186194

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 CCDC64B RAB40C MI:0362 inference MI:0461 interaction database PSD RAB40C MI:0045 experimental interaction detection MI:0461 interaction database PLIN3 RAB40C MI:0362 inference MI:0461 interaction database LDHA RAB40C MI:0362 inference MI:0461 interaction database UBC RAB40C MI:0045 experimental interaction detection MI:0461 interaction database RABGGTB RAB40C MI:0045 experimental interaction detection MI:0461 interaction database RAD23B RAB40C MI:0362 inference MI:0461 interaction database POLR2F RAB40C MI:0362 inference MI:0461 interaction database GSTO1 RAB40C MI:0362 inference MI:0461 interaction database RAB40B RAB40C MI:0045 experimental interaction detection MI:0461 interaction database TCEB1 RAB40C MI:0045 experimental interaction detection MI:0461 interaction database TCEB2 RAB40C MI:0045 experimental interaction detection MI:0461 interaction database OSR2 RAB40C MI:0362 inference MI:0461 interaction database OSR1 RAB40C MI:0362 inference MI:0461 interaction database PREX1 RAB40C MI:0362 inference MI:0461 interaction database BICD2 RAB40C MI:0362 inference MI:0461 interaction database TTN RAB40C MI:0362 inference MI:0461 interaction database CUL5 RAB40C MI:0045 experimental interaction detection MI:0461 interaction database BICD1 RAB40C MI:0362 inference MI:0461 interaction database DCUN1D1 RAB40C MI:0045 experimental interaction detection MI:0461 interaction database TOE1 RAB40C MI:0045 experimental interaction detection MI:0461 interaction database ANKRD27 RAB40C MI:0045 experimental interaction detection MI:0461 interaction database RAB40C DPYSL5 MI:0362 inference MI:0461 interaction database RAB40C UBE2O MI:0362 inference MI:0461 interaction database RAB40C GSTO2 MI:0362 inference MI:0461 interaction database RAB40C RNF7 MI:0045 experimental interaction detection MI:0461 interaction database RAB40C DNAJB11 MI:0362 inference MI:0461 interaction database RAB40C INO80 MI:0362 inference MI:0461 interaction database