PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus PLCG2 KCTD17 25814554 biogrid,intact exp P G P GP G P P G P P P GP P G P P P P GP PLCG2 MED28 16964398 mint,intact exp G G G G G GP G G GP G G G GP G G G GP GP G G GP G G G G G GP GP G PLCG2 FCER1G 10469124 innatedb,hprd,bci exp G G G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G G HSPD1 PLCG2 25814554 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 ZKSCAN7 25814554 biogrid,intact exp GP P P GP GP P GP P P G G P G P P GP GP GP G PLCG2 ELK1 25814554 biogrid,intact exp G GP G G G GP G GP GP G GP G GP G G GP GP GP G G GP G G G GP GP GP GP G PLCG2 ZNF512B 15231748 biogrid,i2d,mint,intact exp G GP G G G GP G GP GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PSMD3 PLCG2 25814554 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 CD79B bci exp G G GP G G G G GP G G G G G G G GP G G NPM1 PLCG2 9819383 hprd,i2d,bci exp G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLXNB1 PLCG2 19805522 biogrid exp P G P GP G P GP G GP G GP P G GP GP GP G GP G GP GP P G MAPT PLCG2 18467332 innatedb exp G GP G G G GP G GP GP G GP G G GP G G GP G G G G G G GP G G GP GP G PLCG2 ISL1 25814554 biogrid,intact exp G P G G P G G P P G G GP G G GP G G G G GP G ESD PLCG2 25814554 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP G G GP GP G G G G G G G GP GP GP GP G FSBP PLCG2 25814554 intact exp P P P P P P P P P P P P P P P P PLCG2 GABPB2 25814554 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G PLCG2 LHX8 25814554 biogrid,intact exp PLCG2 EPYC 25814554 biogrid,intact exp P GP P PTTG1 PLCG2 25814554 biogrid,intact exp G G G G GP G G G GP G G G G GP G GP G G G G GP G G G GP GP G GP G PLCG2 SETD9 25814554 biogrid,intact exp G P P G G GP G GP G P G GP P G GP G G G GP P GP G PLCG2 KHDRBS1 10467411 hprd exp G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 TWIST2 25814554 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G PLCG2 LIME1 16249387 hprd exp P P P P P P P P P P P P P P P PLCG2 ASB9 25814554 biogrid,intact exp G G G G G GP G G G G G G G G G G GP G PLCG2 BOP 25814554 biogrid,intact exp G GP G G G GP G P GP G GP G GP GP G G GP GP G G P G G GP G G GP GP G PLCG2 JAK1 14978237 innatedb,hprd,bci exp G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP G GP GP G AR PLCG2 24728074 intact exp G G G G G G G G G G G G G G G G G G G G G G G G GP G PLCG2 RALBP1 25814554 biogrid,intact exp G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 RAD54B 25814554 biogrid exp, ortho G GP P G GP P P P G P P GP G P P P GP P PLCG2 PLCG2 10469124,9819383, 23023127 innatedb,hprd,i2d exp, ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 TEC 15184383, 25402006, 23023127 hprd,bci exp, ortho, pred P P P P P P P P P P P P P P P P LYN PLCG2 10469124,10981967,15144186,12181444,8395016,7682059, 25402006, 23023127 innatedb,hprd,biogrid,bci exp, ortho, pred G G G G GP GP G G GP G G G GP GP G GP GP G G G GP G G GP GP GP G G FYN PLCG2 15144186,12181444,7682059,8395016, 25402006, 23023127, 21836163 hprd,biogrid,bci exp, ortho, pred G GP G G GP GP G G GP G GP G G GP G G GP G G G G G G G G GP G G G PLCG2 EPOR 15953601,15644415, 25402006 hprd,intact,bci exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G EGFR PLCG2 24658140,25241761,16273093,25402006, 25402006 biogrid,i2d,mint,intact exp, ortho, pred G GP G GP G G GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G PLCG2 BLNK 11274146,21822214, 25402006, 23023127, 21836163 hprd,biogrid,intact,bci exp, ortho, pred G P G G GP GP G P GP G GP G G GP G GP GP GP G G GP G G GP GP GP P G PLCG2 BLK 8395016, 25402006, 21836163 hprd,biogrid,bci exp, ortho, pred G P P P P P P GP P P P GP P P PLCG2 BTK 10981967,17290227,12093870,11507089, 25402006, 23023127, 21836163 hprd,biogrid,bci exp, ortho, pred G G GP G G GP GP G G GP G MET PLCG2 24728074, 25402006 intact exp, ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 SYK 10469124,16449524,10981967,12470302,10933389,12771181, 25402006, 23023127, 21836163 innatedb,hprd,biogrid,bci exp, ortho, pred G G G G GP GP G GP G GP G GP GP G GP GP G G G G G G GP GP GP GP G PLCG2 ITK 15184383, 25402006, 23023127 hprd,bci exp, ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 CTTN 10469124, 23023127 innatedb exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 PLD1 16923831, 23023127 biogrid,bci exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G P G G P GP GP GP GP G ERBB2 PLCG2 25241761,16273093, 25402006 biogrid,i2d,mint,intact exp, pred G G G G G G G G GP G GP G G G G GP G G G G GP G G G GP G G G G PLD2 PLCG2 25402006, 23023127 bci exp, pred G GP G G GP GP G GP GP G GP G GP G G GP GP GP G G GP G G G GP G GP GP G PLCG2 LAT2 12514734, 25402006 hprd,biogrid exp, pred G G G G GP G G G G G GP GP G G G G G G G G G G GP G G KIT PLCG2 24728074, 25402006 intact exp, pred G G G G GP GP G G G G G GP G G G GP GP G G G G G G G G G G PLCG2 PRKD1 8885868, 21836163 hprd,biogrid exp, pred G GP G P GP G GP GP G GP GP G G GP GP GP G G GP G G GP GP G GP GP G PLCG2 GRB2 10469124,17474147, 25402006, 23023127 innatedb,i2d,intact exp, pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G HCK PLCG2 15144186,12181444,7682059, 25402006, 23023127, 21836163 hprd,bci exp, pred G G G G GP GP G G G G P G GP G G GP GP GP G G GP G G GP GP GP GP P G PLCG2 DAPP1 10770799, 21836163 hprd exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 PRKCA 16923831, 21836163 biogrid exp, pred G GP G G GP GP G GP GP G GP G G GP G GP GP G G G GP G G GP GP G GP GP G PLCG2 PLCD1 21836163 bci exp, pred G GP G G G GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP G GP GP G PLCG2 CBLB 12093870, 23023127 hprd,biogrid,bci exp, pred G GP G G G GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 PLCG1 25241761, 23023127, 21836163 intact,bci exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G VAV1 PLCG2 10981967, 25402006, 23023127, 21836163 biogrid exp, pred G GP G GP GP G P P G P G GP GP G GP GP G G G GP G G P P GP GP GP G PLCG2 IRS1 22974441, 23023127 biogrid exp, pred G GP G P GP G G GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP P G PLCG2 PIK3R1 25241761,17474147, 23023127 i2d,mint,intact exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 SHC1 12135708,10623845, 25402006, 23023127, 21836163 hprd,biogrid,bci exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G LCK PLCG2 15144186,12181444,7682059, 25402006, 23023127, 21836163 hprd,bci exp, pred G G GP G G G G G G GP G G G G G GP G TP53 PLCG2 25814554, 23023127 biogrid,intact exp, pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G PLCG2 GAB2 12135708, 25402006, 23023127 hprd,biogrid,bci exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G JAK2 PLCG2 14978237, 25402006, 23023127 innatedb,hprd,bci exp, pred G GP G G GP GP G GP GP G GP GP GP G P GP GP P G G G GP GP GP GP PLCG2 PTPN11 12135708, 25402006 biogrid exp, pred G GP G G G GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 WAS 10590061, 23023127 innatedb exp, pred G GP G G GP GP G G GP G G G GP GP G G GP G G G GP G G GP G GP GP GP G LAT PLCG2 10469124, 25402006 hprd,bci exp, pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP G G G PLCG2 FLT1 9398617, 21836163 hprd,bci exp, pred G G G GP G GP GP G G G G G G G GP G G G GP G G GP G G G G G PLCG2 KDR 9398617, 23023127 hprd exp, pred G GP G G G G G G GP G GP G GP G G G G G G G G G G G G G G GP G PLCG2 SH3BP2 11390470, 25402006 hprd,mint,intact exp, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G CD19 PLCG2 10706702,15187135, 25402006 hprd,bci exp, pred G G G GP P GP G G GP GP G P P GP G G GP GP GP G PLCG2 LCP2 10469124, 23023127, 21836163 hprd,i2d,bci exp, pred G G G GP G G G GP GP G G G G G G GP G PLCG2 GAB1 24728074,11507676, 25402006 hprd,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 NCKIPSD ortho G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 TMED9 ortho G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 TMEM181 ortho G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 PHC2 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G GSN PLCG2 25402006, 21836163 ortho, pred G GP G G GP GP G G GP G GP G GP GP G G GP GP G G GP G G G G GP GP G G ZBTB7B PLCG2 25402006 ortho, pred G GP G GP P G GP G G G G GP G GP P G GP G G G GP G GP P PLCG2 REPS1 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 SH3KBP1 25402006, 23023127 ortho, pred G G G G GP GP G G G G G G G GP G G GP G G G GP G G G G GP G G G PLCG2 PDCD6IP 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP G G GP GP GP G G GP G G GP GP G GP GP G SPRY2 PLCG2 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP G GP GP G CRYAB PLCG2 25402006 ortho, pred G G G G G GP G GP GP G GP G G G G G GP G G G GP G G GP G G G G G PLCG2 UCK1 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G HAX1 PLCG2 25402006 ortho, pred G GP G G GP G G GP GP G GP G GP GP G GP G GP G G GP G G GP GP GP GP GP G PLCG2 CAP1 25402006 ortho, pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G FN1 PLCG2 25402006 ortho, pred G G G G GP GP G GP GP G GP G G G G G GP GP G G GP G G G G G G G G PLCG2 INPP5D 25402006, 23023127 ortho, pred G GP G G GP GP G GP G G GP G G GP G G GP GP G G G G G GP G GP G G G TOX4 PLCG2 25402006 ortho, pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 FHL2 25402006 ortho, pred G GP G G GP GP G GP GP GP G GP G G GP GP GP G G GP G G GP GP G GP GP G PLCG2 MERTK 25402006 ortho, pred G GP G G G GP G GP G G GP G GP G G G GP GP G G G G G G G G GP GP G PLCG2 FLNA 25402006 ortho, pred G G G G GP GP G G GP G GP G GP GP G G GP GP G G GP G G G G G GP GP G PLCG2 ERRFI1 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G PLCG2 SPTBN1 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 NBR1 25402006 ortho, pred G GP G G G GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP G GP GP G NDC80 PLCG2 25402006 ortho, pred G G G G G TRIM27 PLCG2 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G EPB41L2 PLCG2 25402006 ortho, pred G G G G GP GP G G GP G GP G GP GP G G GP GP G G G G G G G GP G GP G PLCG2 BACH2 25402006 ortho, pred G P G G GP GP G GP GP G GP G GP GP G GP GP GP G G P G G GP GP GP GP P G DVL2 PLCG2 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 SOS2 25402006 ortho, pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 MAP3K11 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G ITGAM PLCG2 23023127 pred G G G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G PLCG2 MICB 23023127 pred G G G G G G G G G G G G G G G G G G G G G PLCG2 CRK 23023127 pred G G G G G G G GP GP G GP G G G G GP G G G G GP G G GP GP G GP G G PLCG2 FRK 25402006, 23023127 pred P P P P P P P P P P P P P P SH3D21 PLCG2 23023127 pred GP G G GP P G GP GP G GP G P GP GP GP P G G GP G GP GP P P GP G PLCG2 SH2B1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PF4 PLCG2 23023127 pred G G G G GP G G G G G G G G G G G G G G G G G G G PLCG2 SH3RF2 23023127 pred P P GP P P P P P P P GP PLCG2 PIK3R3 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G G G GP G G G GP GP GP GP G PLCG2 RNF149 23023127 pred G GP G G G GP G GP GP G GP G GP G G GP GP GP G G G G G GP GP G GP GP G PLCG2 ARHGEF6 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G G G G G G G GP G GP G G PLCG2 EIF5AL1 23023127 pred PLCG2 XCL1 23023127 pred G G G P G GP GP G G G G PLCG2 ABI1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G EGF PLCG2 23023127 pred P P P GP P GP P P G P P G P G G GP GP P P P PLCG2 PIP4K2A 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 L3MBTL1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 SH2D5 23023127 pred P G G GP GP GP GP G P P G GP GP P G GP G P P P P GP PLCG2 MPP1 23023127 pred G GP G G GP GP G G GP G GP G GP G G GP GP G G G GP G G G GP G G GP G PLCG2 DGKE 23023127 pred G G G G GP GP G GP GP G G G GP GP G GP GP GP G P G G P GP GP GP GP G PLCG2 ITGAL 23023127 pred G G G GP G G G G G GP GP G G G G G G G G G G GP G G PLCG2 SH3YL1 23023127 pred G G G G G GP G G GP G GP G GP GP G GP GP G G G GP G G G GP G GP GP G MYO1F PLCG2 23023127 pred G G G G GP G G G G G G G GP G G G G G G G G G G GP G G G PLCG2 ITSN1 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP G GP GP G PLCG2 ISYNA1 23023127 pred G GP G G GP GP G G GP G GP G G G G G GP GP G G GP G G GP G G GP GP G PLCG2 NKX2-5 23023127 pred G G G G ITGB1 PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G SRGAP2 PLCG2 23023127 pred G G G G G G G G G G G G G G G G G G HGF PLCG2 23023127 pred G GP G G GP P G GP GP GP G GP GP G P GP GP G G GP G GP P GP GP P G CAT PLCG2 25402006 pred G GP G G GP G G G G G GP G GP G G GP G G G G G G G G GP G G G G PLCG2 MAP3K9 23023127 pred GP G P GP G GP G GP G P G G GP GP P G G GP G G GP GP GP GP GP G PLCG2 UBASH3A 23023127 pred P P G P P P G CD46 PLCG2 23023127 pred G GP G G G GP G G GP G GP G GP GP G GP GP G G G GP G G G GP GP GP GP G PLCG2 RUSC1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP G GP GP G KRT1 PLCG2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G C4BPA PLCG2 23023127 pred G G G G GP GP G G GP G G G G G G GP G G G G G G G G G G G PLCG2 AMPH 23023127 pred G G G G GP G G GP G G G G G GP G G G G G G G G G G G PLCG2 VAV3 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G PLCG2 EPAS1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 GP6 21836163 pred P G G GP GP G G GP G P G GP G GP GP GP G G GP G G G GP G GP GP G FFAR1 PLCG2 23023127 pred PLCG2 CORO1A 23023127 pred G G G GP GP G G G G G G GP G G GP G G G G G GP G G PLCG2 HERPUD2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PMM2 PLCG2 23023127 pred G GP G GP P G GP GP GP G GP GP G GP P G G G G G G P GP G GP P G PECAM1 PLCG2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GRAP2 PLCG2 25402006, 23023127 pred P P P P P P P P P P P P P P PLCG2 ELF1 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 PACSIN1 23023127 pred G GP G G P G P GP G PLCG2 PEX13 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 TMUB1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP G GP GP G SASH3 PLCG2 23023127 pred G G G G G GP G G GP G G G GP GP G G GP G G G GP G G G G GP GP GP G ITGA4 PLCG2 25402006, 23023127 pred G G G G FRS3 PLCG2 25402006 pred G G G G GP G G GP G G G G G G G G G G G G GP G G G G G GP G G RIMBP3C PLCG2 23023127 pred P P P P PLCG2 GRB14 23023127 pred GP P P G GP GP GP G P GP P P G G GP P GP P P GP PLCG2 SHC4 23023127 pred G G G G G G G G G PLCG2 GNA15 23023127 pred G P G G GP GP G GP GP P G GP G G P GP G G G G P GP G GP P G PLSCR1 PLCG2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G VWF PLCG2 23023127 pred G G G G GP GP G G GP G G G G G G GP G G G G G G G G G G G G PLCG2 PLA2G5 21836163 pred GP G G GP GP G GP P G GP G GP GP P GP G G G GP G G GP P P GP GP G PLCG2 ARHGAP4 23023127 pred G G G GP G GP GP G G G GP G PLCG2 SH3GL1 23023127 pred G GP G G GP GP G GP GP G GP G GP G G GP GP GP G G GP G G GP GP G GP GP G PLCG2 SUMO4 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G G GP GP G G GP G G GP G GP GP GP G PLCG2 MAPK8IP1 23023127 pred P G P GP G P P G P P P P GP G P P P P P GP SERPING1 PLCG2 23023127 pred G G G G G G G G GP G G G G G G G G G G G G G G G G G G G G A2M PLCG2 23023127 pred G G G G G GP G G GP G G G G G G G GP G G G GP G G G G G G G G PLA2G10 PLCG2 21836163 pred P P P P P P P P P P P P P P P P PLCG2 MAPK8IP2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G COL1A1 PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G G GP GP G G GP G G G G G GP GP G PLCG2 SHB 25402006, 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G INSR PLCG2 25402006, 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G IGF1R PLCG2 25402006 pred G GP G G G G G GP GP G GP G GP GP G GP G G G G GP G G G GP GP GP GP G PLCG2 NCF4 23023127 pred G G G GP G GP GP G G G G GP G PLCG2 NCF4 23023127 pred G G G GP G GP GP G G G G GP G ALOX5 PLCG2 25402006 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G GP G G P GP GP GP P G F2 PLCG2 23023127 pred P P P G P PLCG2 ADORA2A 23023127 pred PLCG2 MX2 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G G G GP G G G GP GP GP GP G PLCG2 RIPK1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PDGFRB PLCG2 25402006, 21836163 pred G G G G G GP G G G G GP G G G G G GP GP G G GP G G G G G GP GP G PLCG2 SLC8A1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP P G G G GP GP G GP P G PLCG2 PIK3CG 23023127 pred G G G G G G G G G G G G G G G G PLCG2 TXNDC5 23023127 pred P P P P P P P CIDEA PLCG2 23023127 pred G G G G G G G G PLCG2 CASS4 23023127 pred P P P P P P P P P P GP P P P CD79A PLCG2 25402006 pred G G G GP G G G G GP GP G G G G G G G G G G G GP G G G PLCG2 C1RL 23023127 pred G G G GP P G GP GP GP G G G G GP P G G G P G G GP GP GP P G ARHGEF9 PLCG2 23023127 pred G GP G P GP G GP GP G GP G G G G G GP G G G GP G G P G GP G P G CSF1R PLCG2 25402006 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 NFAM1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G GP GP GP GP GP G PLCG2 BMX 23023127 pred G P G GP P G GP GP P P G GP P G P P GP P P FCGR1A PLCG2 25402006 pred PLCG2 UBASH3B 23023127 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FAM109B 23023127 pred G G G G G GP G GP GP G G G G G G GP GP G G G GP G G GP GP G GP G G ZBTB7A PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G PLCG2 RASA1 23023127 pred G G G G GP GP G G G G G G G G G G GP G G G GP G G G G G GP G G PLCG2 FCHSD1 23023127 pred P P P P P P P GP P P P G P P P GP P P RBP4 PLCG2 23023127 pred G G G G G G G GP G G G G G G G G G G G G G P PLCG2 NOSTRIN 23023127 pred G GP G P GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G PLCG2 IL10RA 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 MYO15B 23023127 pred PLCG2 BCL6 23023127 pred G G G G GP G G G G G G G G GP G G G G G G GP G G G G GP G G G HSP90AA1 PLCG2 25402006 pred G GP G G G GP G G GP G G G G G G G GP G G G GP G G G G G G GP G BCAR3 PLCG2 25402006, 23023127 pred G GP G P GP G GP GP G GP G GP GP G GP GP G G GP G G GP GP G GP GP G PLCG2 SHANK2 25402006 pred G P GP G GP G GP G GP P G GP GP G G GP G G P GP GP GP P PLCG2 GPR183 23023127 pred G G G G P G GP GP P GP GP G GP P P G G P GP GP GP P GNAO1 PLCG2 23023127 pred GP G GP G G GP G G G G G GP G G G G G G G G G PLCG2 RAD23A 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 SCARF1 23023127 pred G GP G GP P GP GP GP G GP GP G GP P P GP G GP GP GP GP P G PLCG2 IL16 23023127 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP G G G LY75 PLCG2 23023127 pred G G G G G G G G G G G G G G G G G ITGB2 PLCG2 25402006 pred G GP G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G G PIK3R2 PLCG2 25402006, 23023127, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SELP PLCG2 23023127 pred G G G G GP G G G GP G G G G G G G G G G G G G G G G G G G G PLCG2 FLT3 23023127 pred G P G G GP GP G GP GP G GP G P GP P GP GP G G GP G GP GP P P GP G PLCG2 RRAS2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G SUPT5H PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G COL2A1 PLCG2 23023127 pred G G G P P G G P GP G G PLCG2 SP100 23023127 pred G GP G GP P G GP GP GP G GP GP G GP P GP G GP G G GP GP GP GP P G INPPL1 PLCG2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 CRKL 23023127 pred G G G G GP GP G G GP G G G GP GP G GP GP G G G GP G G G GP GP GP G G PLCG2 IL15 23023127 pred G GP P P G G GP GP GP GP G GP P G G GP G G G GP GP GP P G PLCG2 PLCB4 21836163 pred G G G G G G G G G G G G G G G G G G G G G G CFB PLCG2 23023127 pred G GP G G G G G G G G GP G G G G G G G G G G G G GP G PLCG2 PLCD3 21836163 pred G P G P GP G GP P G P P G GP GP GP GP G GP GP P GP G PLCG2 SRGAP1 23023127 pred G GP G GP G G GP G GP G G G G GP GP G G G G G GP G G GP G CTNND1 PLCG2 25402006 pred P P P P P P P P P P P P P P P P PLCG2 COMP 23023127 pred G G G G G PLCG2 LIPG 23023127 pred P GP G GP GP G G G P GP G G GP G G G G G G G P G G G PLCG2 CASP1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP G GP GP G ROS1 PLCG2 23023127 pred G G G P GP P G GP G G G G G GP G G CD48 PLCG2 25402006 pred G G G G G G G G G G G G G GP G G G G G G G G G G G G G G G NPHP1 PLCG2 25402006, 23023127 pred P P G P P GP P P P P G G G P G P P GP PLCG2 PACSIN3 23023127 pred G GP GP G GP P P G P G G GP GP GP G GP G G GP GP GP P G F7 PLCG2 23023127 pred GP G G GP GP G GP GP G GP G GP GP G P GP G G G GP G GP GP G GP GP G EPO PLCG2 25402006 pred GP P G G G G GP P G P G G G G G G P PLCG2 RASGRP4 23023127 pred P G G P P GP P P P G P P G P G GP GP P P C1R PLCG2 23023127 pred G G G G GP GP G G G G GP G GP GP G GP GP GP G G G G G G GP GP G GP G PLCG2 UBQLNL 23023127 pred P P P P P P G P P P GP PLCG2 CD86 23023127 pred G G G G GP GP G G P G G GP GP G GP GP G G GP G G P GP GP P PLCG2 ARHGEF7 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 ADORA1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SKI PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP G G GP GP GP G G GP G G GP GP GP GP GP G KALRN PLCG2 23023127 pred P G P GP G P P G P P P P GP P P P GP P P PLCG2 IL4R 23023127 pred G GP G G GP P G GP GP G GP G GP GP G GP GP GP G GP G G P GP GP GP GP G PLCG2 STK4 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 DRD3 23023127 pred PLCG2 STAM 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G G GP G GP GP G PLCG2 PLA2G2E 21836163 pred P P P P P G P BCR PLCG2 25402006 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP G GP GP G PLCG2 TGFBR2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DCLK1 PLCG2 23023127 pred G G G GP G G GP G GP G GP GP GP G G P G G G GP GP GP P G PLCG2 CCL8 23023127 pred G G G G G G G G G G G G G G G G G G G G G G PLCG2 GNMT 23023127 pred P G G P P G GP P G G G GP P DOK2 PLCG2 25402006 pred G G G GP G G G G GP GP G G G G G G G G GP G G PLCG2 ABL2 23023127 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KLHL6 23023127, 21836163 pred G P G GP P P GP P GP GP GP P P P GP GP GP P PLCG2 PIK3CA 23023127 pred G GP G P GP G GP GP G GP G GP GP G P GP GP G G P G G GP GP GP GP GP SP1 PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 CD2AP 23023127 pred G GP G GP P G G GP GP G GP GP G GP GP G G G GP G G G GP GP GP GP PLCG2 UBXN2A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 EGR1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G NCF1B PLCG2 23023127 pred CD2 PLCG2 25402006 pred G G G G G G G G G G G G G GP G G G G G G G G G G G GP G G G RIMBP3B PLCG2 23023127 pred PLCG2 HHEX 23023127 pred G G G G GP G G G GP G GP G G GP G G G G G G G G G GP G GP GP G PLCG2 UBTD1 23023127 pred G GP G G G GP G GP GP G GP G GP G G G GP GP G G P G GP G G G GP G PLCG2 SHD 25402006 pred G G GP G P G P G G P G P P PLCG2 SH2D2A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 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G GP P G GP GP GP G G G G GP P GP G G P G G G GP G GP P G DFFA PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 OBSCN 23023127 pred G P P P GP GP GP P GP G P P P G P G G GP GP GP GP P PLCG2 PLA2G3 21836163 pred P P P P P P P P P P P P GP P P P P PLCG2 TXK 23023127 pred G G G P G G G G P G PLCG2 BCL6B 23023127 pred G GP G G G G G GP GP G GP G G G G GP G G G G G G G G GP G GP GP G PLCG2 SSH1 23023127 pred G GP G G G GP G G GP G GP G GP GP G GP GP G G G GP G G G GP GP GP GP G PLCG2 PLCE1 23023127, 21836163 pred G P G P GP G GP GP G GP GP P G GP GP GP G G P G G GP GP GP GP P G PLCG2 PLA2G2D 21836163 pred P P P P P P G P P P P P P P PLCG2 SWAP70 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G C8A PLCG2 23023127 pred G PLCG2 CAMK2B 21836163 pred G G G G GP G GP G G G G G GP G G G G GP G G GP G PLCG2 TNFRSF14 23023127 pred G GP G G GP G G GP GP G GP G GP GP G GP G G G G G G G G GP GP GP GP G PLCG2 MYLIP 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 PSEN2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G FCGR3A PLCG2 25402006 pred P P P P P P P RIMBP2 PLCG2 23023127 pred P G P GP G P P G GP P G GP GP G G P GP P P GP P G PLCG2 SHF 25402006 pred GP G P GP G P G G P G P P GP G G G P P GP PLCG2 GRB10 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G IRS4 PLCG2 25402006 pred G GP G G G GP G GP GP G GP P GP G GP GP G G G GP G GP GP GP GP GP G ASAP2 PLCG2 25402006 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP P GP GP G TG PLCG2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 STAB1 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 ZNF175 23023127 pred G GP G G G G G GP GP G GP G GP G G G G GP G GP G G G G G GP G G MMP2 PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 IKZF1 23023127 pred G G G G GP G G G G G G G GP G G G G G G G G G G G GP G G G BIN1 PLCG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G FYB PLCG2 25402006, 23023127 pred G G G GP G G G G G G G GP G G G G G G G G GP G COL3A1 PLCG2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G KRAS PLCG2 23023127 pred G G G G GP GP G G GP G GP G G GP G GP GP G G G G G G GP GP G GP GP G PLCG2 HOMER1 23023127 pred G G GP G GP G G G G G GP G G G G G G G G G G G PLCG2 ASAP1 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 HLX 23023127 pred G GP G GP P G GP GP GP G GP GP G G P GP G G GP G GP G GP GP P G PLCG2 ABI2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 VEGFC 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 ITPR3 21836163 pred G GP P G G GP GP G GP GP G GP GP G G GP G G G GP G GP GP G PLCG2 DGCR8 23023127 pred P P P P P P P P P P P P P P P P P PLCG2 BAIAP2L1 23023127 pred GP P P G P GP GP G GP P G GP P P G G GP G G P GP P GP GP PLCG2 ARF6 23023127 pred G GP G G G GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 INPP1 21836163 pred G GP G G GP GP G G GP G G G GP G G GP GP G G G G G G G GP G G GP G SOCS3 PLCG2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G GP G G GP GP GP G G GP G G GP GP G GP GP G PLCG2 EPS8L3 23023127 pred G G G G GP GP G GP GP G P G GP G G GP GP GP G G G G GP GP G GP G PLCG2 KIF13B 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G G GP G GP GP G PLCG2 SLA 25402006, 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G EREG PLCG2 23023127 pred P G G P P P P P P P GP P P P P P P INHBA PLCG2 23023127 pred P G GP P GP P P G GP P P P GP G GP G P GP P P P G FCER2 PLCG2 25402006 pred P P GP PLCG2 SH3GLB2 23023127 pred G GP G G G GP G G GP G GP G GP G G GP G G G GP G G G G GP GP GP G PLCG2 ATP7B 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP P GP GP G B3GAT3 PLCG2 23023127 pred GP G GP G P G GP G G GP G P GP G G G G G G GP G GP P G PLCG2 TYRO3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 LIMS1 23023127 pred G GP G G G GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G NEBL PLCG2 25402006, 23023127 pred G GP G G G G G GP GP G GP G GP GP G GP G G G G G G G G GP P GP G G CDIPT PLCG2 21836163 pred G GP G G G GP G G GP G G G G GP G G GP G G G G G G G G G GP G G PLCG2 ARHGEF16 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 ZAP70 25402006, 23023127 pred G G GP G G G GP G G GP G RRAS PLCG2 23023127 pred G GP G P GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 DGKA 21836163 pred G G G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G TYROBP PLCG2 25402006 pred G G G G GP GP G G G G G G GP GP G G GP G G G G G G G G GP G G G C1S PLCG2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PLCG2 SH2B3 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 EIF5A 23023127 pred G GP G G G GP G GP GP G GP G GP G G GP GP G G G GP G G G GP G GP GP G PLCG2 ITPR2 21836163 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP G G G GP G G GP GP GP GP GP G IL2RB PLCG2 25402006 pred G G G G GP G G G G G G G G GP G G G G G G G G G G G GP G G G NTRK1 PLCG2 25402006, 23023127 pred P P G P P P P P P P P P P P PLCG2 JAG2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G SOCS1 PLCG2 25402006, 23023127 pred G GP P P GP GP GP G GP GP G GP P GP G G GP G P GP GP GP GP G SRC PLCG2 25402006, 23023127 pred G GP G GP GP G G GP G G G G GP GP G G G G G G GP GP GP GP G ARHGAP32 PLCG2 25402006 pred G GP G P GP G GP GP G GP G G G G GP GP G G G GP G G GP GP G GP GP G PLCG2 SND1 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G CD44 PLCG2 25402006 pred G G G G GP GP G G GP G G G GP GP G G GP GP G G G G G G G GP G G G FGR PLCG2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G P G G G GP GP GP P G PLCG2 ATP7A 23023127 pred G GP G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G SASH1 PLCG2 25402006, 23023127 pred G GP G G GP GP G GP GP G GP G GP G G G GP G G G GP G G GP G G GP GP G PLCG2 NKX2-3 23023127 pred P P GP P P P GP P P GP G G P PLCG2 STAT6 23023127 pred G GP G G GP GP G G GP G GP G GP GP G GP GP GP G G GP G G G GP GP GP GP G PLCG2 SUMO2 23023127 pred G GP G G GP GP G GP GP G GP G GP GP G GP GP GP G G GP G G GP GP GP GP GP G PLCG2 CACNA2D4 23023127 pred G P G GP GP G GP P GP P GP GP P G G GP G GP GP GP P P G PLCG2 DYNLT1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MASP2 PLCG2 23023127 pred P G G P P GP P G P P P P P P P P P TLR2 PLCG2 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G MUC1 PLCG2 25402006 pred G P GP GP GP P G GP G GP G G GP GP GP G PIK3CD PLCG2 21836163 pred G G G G G G G G G G G G G GP G G G G G G G G G G G GP GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P16885 Q8WV28-3 affinity chromatography technology 21822214 physical association X 2 P16885 Q8WV28-3 affinity chromatography technology 21822214 physical association X 2 P16885 A0A024R499 unspecified method 22974441 direct interaction X 2 P16885 affinity chromatography technology 16923831 physical association X 2 P16885 Q06124-2 affinity chromatography technology 12135708 physical association X 2 P16885 Q06124-2 affinity chromatography technology 12135708 physical association X 2 P16885 Q13191 affinity chromatography technology 12093870 physical association X 2 P16885 Q9GZY6 affinity chromatography technology 12514734 physical association X 2 P16885 P15498 affinity chromatography technology 10981967 physical association X 2 P16885 O43157 affinity chromatography technology 19805522 physical association X 2 P0CG48 P16885 affinity chromatography technology 24816145 physical association X 2 P0CG48 P16885 affinity chromatography technology 21906983 physical association X 2 P16885 Q13393-2 affinity chromatography technology 16923831 physical association X 2 P16885 P00533 unspecified method 16273093 direct interaction X 2 P16885 P04626-3 unspecified method 16273093 direct interaction X 2 P16885 Q96KM6 two hybrid 15231748 direct interaction X 2 P16885 P00533 two hybrid 25402006 direct interaction X 2 P16885 P29353-5 affinity chromatography technology 10623845 physical association X 2 P16885 A8K379 affinity chromatography technology 8395016 physical association X 2 P16885 A8K379 pull down 8395016 direct interaction X 2 P16885 P06241-3 pull down 8395016 direct interaction X 2 P16885 P51451 pull down 8395016 direct interaction X 2 P16885 Q9UQC2 affinity chromatography technology 12135708 physical association X 2 P16885 Q9UQC2 affinity chromatography technology 12135708 physical association X 2 P16885 P29353-5 affinity chromatography technology 12135708 physical association X 2 P16885 Q15139 affinity chromatography technology 8885868 physical association X 2 P16885 Q06187 affinity chromatography technology 12093870 physical association X 2 P16885 A0A024R244 affinity chromatography technology 10981967 physical association X 2 P16885 Q06187 affinity chromatography technology 10981967 physical association X 2 P16885 A8K379 affinity chromatography technology 10981967 physical association X 2 P16885 coimmunoprecipitation 10469124 association C 3 P16885 pull down 10469124 association C 4 P16885 anti bait coimmunoprecipitation 16923831 association C 3 P16885 Q13094 coimmunoprecipitation 10469124 association X 2 P16885 pull down 10469124 association C 4 P16885 A0A024QZD6 coimmunoprecipitation 10469124 association X 2 P16885 anti bait coimmunoprecipitation 21822214 association C 6 P10275 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P10275 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P10275 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P10275 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P10275 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P10275 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 P19235 mammalian protein protein interaction trap 15644415 physical association X 2 P16885 P19235 mammalian protein protein interaction trap 15644415 physical association X 2 P16885 P19235 mammalian protein protein interaction trap 15644415 physical association X 2 P16885 B0LPF3 peptide array 17474147 physical association X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 A0A024RDA0 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 Q13480 P16885 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P04626 P16885 protein array 16273093 direct interaction X 2 P04626 P16885 protein array 16273093 direct interaction X 2 P04626 P16885 proximity ligation assay 25241761 physical association X 2 Q9H204 P16885 peptide array 16964398 physical association X 2 P16885 P78314 pull down 11390470 association X 2 P16885 Q96KM6 two hybrid 15231748 physical association X 2 P16885 P00533 protein array 16273093 direct interaction X 2 P16885 P00533 protein array 16273093 direct interaction X 2 P16885 P27986 peptide array 17474147 physical association X 2 P16885 Q81N23 two hybrid pooling approach 20711500 physical association X 2 P16885 P00533 ubiquitin reconstruction 24658140 physical association X 2 P16885 P00533 luminescence based mammalian interactome mapping 24658140 physical association X 2 P16885 A0A024R759 fluorescence polarization spectroscopy 24728074 direct interaction X 2 P16885 P00533 proximity ligation assay 25241761 physical association X 2 P16885 P19174 proximity ligation assay 25241761 physical association X 2 P16885 P27986 proximity ligation assay 25241761 physical association X 2 P16885 P16885 coimmunoprecipitation 9819383 - X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B CD19 PLCG2 MI:0493(in vivo) 10706702 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_24400 - - PLCG2 ZNF512B MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231748 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(biogrid)|MI:0471(mint)|(intact) MINT_31364|BIOGRID_259290|MINT_60129|UniProt_78454 prey|prey|prey|prey bait|bait|bait|bait PLCG2 SH3BP2 MI:0493(in vivo)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 11390470 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0914(association)|MI:0914(association)|MI:0914(association) MI:0468(hprd)|(intact)|MI:0471(mint)|MI:0471(mint) HPRD_6561|UniProt_68905|MINT_79492|MINT_47605 -|unspecified role|unspecified role|unspecified role -|unspecified role|unspecified role|unspecified role PLCG2 PRKD1 MI:0493(in vivo)|MI:0004(affinity chromatography technology) 8885868 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_6568|BIOGRID_104227 -|bait -|prey PLCG2 MED28 MI:0081(peptide array)|MI:0081(peptide array)|MI:0081(peptide array)|MI:0081(peptide array) 16964398 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|(intact)|(intact) MINT_70579|MINT_40992|UniProt_167354|UniProt_88756 bait|bait|bait|bait prey|prey|prey|prey MET PLCG2 MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (intact) UniProt_133080 neutral component neutral component PLCG2 GRB2 MI:0096(pull down)|MI:0492(in vitro)|MI:0492(in vitro) 10469124,12514734,17474147 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|- (intact)|MI:0468(hprd)|MI:0468(hprd) UniProt_91661|HPRD_39225|HPRD_39520 bait|-|- prey|-|- PLCG2 LIME1 MI:0493(in vivo) 16249387 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25330 - - PLCG2 LAT2 MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 12514734 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|MI:0468(hprd) HPRD_6570|BIOGRID_106618|HPRD_39225 -|prey|- -|bait|- HCK PLCG2 MI:0492(in vitro) 12181444 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_35493 - - PLCG2 GAB2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 12135708 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_101651|BIOGRID_101647|HPRD_6569 prey|bait|- bait|prey|- KIT PLCG2 MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_132831|UniProt_132688|UniProt_132772|UniProt_132716|UniProt_132879|UniProt_132797|UniProt_132748|UniProt_132913 neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component JAK2 PLCG2 MI:0493(in vivo) 14978237 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_24175 - - PLCG2 DAPP1 MI:0493(in vivo) 10770799 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25329 - - PLCG2 FCER1G MI:0492(in vitro)|MI:0492(in vitro) 10469124 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|- MI:0468(hprd)|MI:0468(hprd) HPRD_26568|HPRD_39520 -|- -|- AR PLCG2 MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy) 24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_132163|UniProt_132299|UniProt_132233|UniProt_132284|UniProt_132320|UniProt_132272 neutral component|neutral component|neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component|neutral component|neutral component UBC PLCG2 MI:0004(affinity chromatography technology) 21906983 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_178534 bait prey FYN PLCG2 MI:0004(affinity chromatography technology)|MI:0493(in vivo) 8395016 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_100274|HPRD_34352 bait|- prey|- PLCG2 BLNK MI:0006(anti bait coimmunoprecipitation)|MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo) 11274146,12514734,21822214 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|-|MI:0915(physical association)|MI:0915(physical association)|- (intact)|MI:0468(hprd)|(biogrid)|(biogrid)|MI:0468(hprd) UniProt_116471|HPRD_39225|BIOGRID_191076|BIOGRID_191084|HPRD_6567 prey|-|prey|prey|- bait|-|bait|bait|- PLCG2 EPOR MI:0231(mammalian protein protein interaction trap)|MI:0231(mammalian protein protein interaction trap)|MI:0231(mammalian protein protein interaction trap)|MI:0493(in vivo)|MI:0231(mammalian protein protein interaction trap)|MI:0231(mammalian protein protein interaction trap) 15644415,15953601 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|MI:0468(hprd)|(intact)|(intact) UniProt_163962|UniProt_163969|UniProt_80005|HPRD_24512|UniProt_80012|UniProt_80013 prey|prey|prey|-|prey|prey bait|bait|bait|-|bait|bait PLCG2 LCP2 MI:0492(in vitro)|MI:0492(in vitro) 10469124 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|- MI:0468(hprd)|MI:0468(hprd) HPRD_6560|HPRD_39520 -|- -|- PLCG2 CBLB MI:0004(affinity chromatography technology)|MI:0492(in vitro) 12093870 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_105529|HPRD_6566 prey|- bait|- LYN PLCG2 MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 10469124,10981967,12181444,8395016 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) HPRD_39520|BIOGRID_100273|BIOGRID_109006|BIOGRID_100200|HPRD_229 -|bait|prey|prey|- -|prey|bait|bait|- PLCG2 PLD1 MI:0493(in vivo)|MI:0004(affinity chromatography technology) 16923831 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_39581|BIOGRID_247649 -|bait -|prey PLXNB1 PLCG2 MI:0004(affinity chromatography technology) 19805522 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_119145 bait prey PLCG2 GAB1 MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0493(in vivo)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy)|MI:0053(fluorescence polarization spectroscopy) 11507676,24728074 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|-|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|MI:0468(hprd)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_132629|UniProt_132513|UniProt_132648|UniProt_132676|UniProt_132605|UniProt_132427|HPRD_6565|UniProt_132409|UniProt_132471|UniProt_132441|UniProt_132568|UniProt_132539|UniProt_132538|UniProt_132389|UniProt_132654|UniProt_132466 neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|-|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|-|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component PLCG2 ITK MI:0492(in vitro) 15184383 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25149 - - PLCG2 JAK1 MI:0493(in vivo) 14978237 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_24173 - - PLCG2 PRKCA MI:0493(in vivo)|MI:0004(affinity chromatography technology) 16923831 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association) MI:0468(hprd)|(biogrid) HPRD_39581|BIOGRID_247648 -|bait -|prey PLCG2 FLT1 MI:0492(in vitro) 9398617 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_187 - - LAT PLCG2 MI:0492(in vitro)|MI:0492(in vitro) 10469124 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|- MI:0468(hprd)|MI:0468(hprd) HPRD_6562|HPRD_39520 -|- -|- PLCG2 KHDRBS1 MI:0492(in vitro) 10467411 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_6563 - - ERBB2 PLCG2 MI:0089(protein array)|MI:0089(protein array)|MI:0686(unspecified method)|MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array) 16273093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact) MINT_45289|MINT_45287|BIOGRID_258397|MINT_75741|MINT_75743|UniProt_83396|UniProt_83456 prey|prey|bait|prey|prey|prey|prey bait|bait|prey|bait|bait|bait|bait PLCG2 PTPN11 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12135708 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_101648|BIOGRID_101649 bait|prey prey|bait PLCG2 BTK MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10981967,11507089,12093870,17290227 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|-|MI:0915(physical association) MI:0468(hprd)|(biogrid)|MI:0468(hprd)|(biogrid) HPRD_5545|BIOGRID_109005|HPRD_31419|BIOGRID_105527 -|bait|-|prey -|prey|-|bait PLCG2 BLK MI:0493(in vivo)|MI:0004(affinity chromatography technology) 8395016 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_4657|BIOGRID_100275 -|prey -|bait PLCG2 IRS1 MI:0686(unspecified method) 22974441 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_245421 prey bait PLCG2 KDR MI:0492(in vitro) 9398617 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_4666 - - NPM1 PLCG2 MI:0492(in vitro) 9819383 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_18628 - - PLCG2 TEC MI:0492(in vitro) 15184383 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25328 - - LCK PLCG2 MI:0492(in vitro) 12181444 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_37245 - - PLCG2 PIK3R1 MI:0081(peptide array)|MI:0096(pull down)|MI:0081(peptide array) 17474147 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) MI:0471(mint)|(intact)|MI:0471(mint) MINT_43190|UniProt_92170|MINT_73233 bait|bait|bait prey|prey|prey PLCG2 SYK MI:0492(in vitro)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 10469124,10981967,12470302 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|- MI:0468(hprd)|(biogrid)|MI:0468(hprd) HPRD_25304|BIOGRID_109004|HPRD_39520 -|bait|- -|prey|- PLCG2 SHC1 MI:0493(in vivo)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10623845,12135708,8226808 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|-|MI:0915(physical association) MI:0468(hprd)|(biogrid)|MI:0468(hprd)|(biogrid) HPRD_40446|BIOGRID_97035|HPRD_6559|BIOGRID_101653 -|bait|-|prey -|prey|-|bait VAV1 PLCG2 MI:0004(affinity chromatography technology) 10981967 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_109003 prey bait EGFR PLCG2 MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array)|MI:0686(unspecified method)|MI:0089(protein array)|MI:0089(protein array)|MI:0089(protein array) 16273093 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|MI:0471(mint)|MI:0471(mint) UniProt_83381|MINT_45288|MINT_45286|BIOGRID_258396|UniProt_83517|MINT_75740|MINT_75742 prey|prey|prey|bait|prey|prey|prey bait|bait|bait|prey|bait|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality A8K379 PLCG2 10981967,8395016,8395016 0004,0004,0096 LC EGFR PLCG2 24658140,24658140,25241761,25241761,24658140,24658140 0090,0729,0813,0428,0112,0004 LC LYN PLCG2 10981967,8395016,8395016 0004,0004,0096 LC PLCG2 SHC1 10623845,12135708 0004,0004 LC PLCG2 SYK 10981967,16449524 0004,0007 LC PLCG2 BTK 10981967,12093870 0004,0004 LC A8K379 PLCG2 10981967,8395016,8395016 0004,0004,0096 LC EGFR PLCG2 24658140,24658140,25241761,25241761,24658140,24658140 0090,0729,0813,0428,0112,0004 LC LYN PLCG2 10981967,8395016,8395016 0004,0004,0096 LC PLCG2 SHC1 10623845,12135708 0004,0004 LC PLCG2 SYK 10981967,16449524 0004,0007 LC PLCG2 BTK 10981967,12093870 0004,0004 LC SH2D1B PLCG2 24642916,24642916 0107,0096 LC PSMD3 PLCG2 25814554,25814554,25814554,25814554 0729,0397,0018,0004 HT LAT PLCG2 24642916,10469124 0107,0019 LC FSBP PLCG2 25814554,25814554 0729,0397 HT PTTG1 PLCG2 25814554,25814554,25814554 0397,0018,1356 HT EGFR PLCG2 24658140,24658140,25402006,24658140,24658140,16273093 0090,0729,0018,0112,0004,0089 LC,HT ERBB2 PLCG2 16273093 0089 HT TP53 PLCG2 25814554,25814554 0397,1356 HT NPM1 PLCG2 9819383 0019 LC MET PLCG2 24728074 0053 HT AR PLCG2 24728074 0053 HT KIT PLCG2 24728074 0053 HT ESD PLCG2 25814554,25814554 0397,0018 HT HSPD1 PLCG2 25814554,25814554,25814554 0397,0018,1356 HT RAC2 PLCG2 19394299 0114 LC PLCG2 PLCG2 9819383 0019 LC PLCG2 EPOR 15644415 0231 LC PLCG2 ELK1 25814554,25814554 0397,1356 HT PLCG2 PIK3R1 17474147 0081 HT PLCG2 WAS 10590061 0059 LC PLCG2 SYK 10469124 0059 LC PLCG2 ISL1 25814554,25814554 0397,0018 HT PLCG2 GRB2 10469124,17474147 0059,0081 LC,HT PLCG2 LCP2 10469124,10469124 0045,0019 LC PLCG2 GAB1 24728074 0053 HT PLCG2 RALBP1 25814554,25814554 0397,0018 HT PLCG2 Q53GA5 25814554 0018 HT PLCG2 LHX8 25814554,25814554,25814554 0397,0018,1356 HT PLCG2 BOP 25814554,25814554 0397,0018 HT PLCG2 Q86SR6 25814554 0018 HT PLCG2 KCTD17 25814554,25814554 0397,0018 HT PLCG2 SETD9 25814554,25814554 0397,0018 HT PLCG2 GABPB2 25814554,25814554 0397,0018 HT PLCG2 TWIST2 25814554,25814554 0397,0018 HT PLCG2 ASB9 25814554,25814554 0397,0018 HT PLCG2 ZNF512B 15231748 0018 HT PLCG2 EPYC 25814554,25814554,25814554 0397,0018,1356 HT PLCG2 CD244 24642916 0107 LC PLCG2 MED28 16964398 0081 LC PLCG2 ZKSCAN7 25814554,25814554 0397,0018 HT PLCG2 RAD54B 25814554,25814554 0018,0004 HT

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9GZY6 P16885 LAT2 PLCG2 0.21 12514734 Q9H204 P16885 MED28 PLCG2 0.21 16964398 P16885 P07948 PLCG2 LYN 0.569 10981967,8395016 Q81N23 P16885 Q81N23 PLCG2 0.126 20711500 P16885 O43157 PLCG2 PLXNB1 0.21 19805522 P16885 P08581 PLCG2 MET 0.183 24728074 P16885 P06241 PLCG2 FYN 0.309 8395016 Q8WV28 P16885 BLNK PLCG2 0.376 21822214 P16885 P04626 PLCG2 ERBB2 0.463 16273093,25241761 Q96KM6 P16885 ZNF512B PLCG2 0.332 15231748 P16885 O95073 PLCG2 FSBP 0.454 25814554 P16885 P10768 PLCG2 ESD 0.286 25814554 Q7L3V2 P16885 BOP PLCG2 0.286 25814554 P19174 P16885 PLCG1 PLCG2 0.196 25241761 P27986 P16885 PIK3R1 PLCG2 0.386 17474147,25241761 Q8WVJ9 P16885 TWIST2 PLCG2 0.286 25814554 Q8NE22 P16885 SETD9 PLCG2 0.286 25814554 Q96DX5 P16885 ASB9 PLCG2 0.286 25814554 P41241 P16885 CSK PLCG2 0.236 26496610 P16885 P00533 PLCG2 EGFR 0.707 16273093,24658140,25241761 P16885 P04637 PLCG2 TP53 0.376 25814554 P16885 P10809 PLCG2 HSPD1 0.376 25814554 P29353 P16885 SHC1 PLCG2 0.376 10623845,12135708 P35568 P16885 IRS1 PLCG2 0.309 22974441 Q99645 P16885 EPYC PLCG2 0.376 25814554 Q9UQC2 P16885 GAB2 PLCG2 0.376 12135708 P78314 P16885 SH3BP2 PLCG2 0.21 11390470 P19235 P16885 EPOR PLCG2 0.376 15644415 P19419 P16885 ELK1 PLCG2 0.376 25814554 Q15311 P16885 RALBP1 PLCG2 0.286 25814554 P51451 P16885 BLK PLCG2 0.309 8395016 Q06124 P16885 PTPN11 PLCG2 0.376 12135708 Q06187 P16885 BTK PLCG2 0.376 12093870,10981967 Q13191 P16885 CBLB PLCG2 0.21 12093870 Q13480 P16885 GAB1 PLCG2 0.332 24728074 P16885 P10275 PLCG2 AR 0.332 24728074 Q8N5Z5 P16885 KCTD17 PLCG2 0.286 25814554 P16885 O95997 PLCG2 PTTG1 0.376 25814554 P16885 O43242 PLCG2 PSMD3 0.454 25814554 P16885 P15498 PLCG2 VAV1 0.21 10981967 P16885 P10721 PLCG2 KIT 0.332 24728074 P17252 P16885 PRKCA PLCG2 0.21 16923831 P62993 P16885 GRB2 PLCG2 0.126 17474147 P43405 P16885 SYK PLCG2 0.21 10981967 P61371 P16885 ISL1 PLCG2 0.286 25814554 Q68G74 P16885 LHX8 PLCG2 0.376 25814554 Q13393 P16885 PLD1 PLCG2 0.21 16923831 Q15139 P16885 PRKD1 PLCG2 0.21 8885868 Q9Y620 P16885 RAD54B PLCG2 0.286 25814554 Q8TAK5 P16885 GABPB2 PLCG2 0.286 25814554 Q9P0L1 P16885 ZKSCAN7 PLCG2 0.286 25814554

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 IGLC7 PLCG2 MI:0362 inference MI:1106 pathways database HAX1 PLCG2 MI:0362 inference MI:0461 interaction database DVL1 PLCG2 MI:0362 inference MI:0461 interaction database DVL2 PLCG2 MI:0362 inference MI:0461 interaction database NDC80 PLCG2 MI:0362 inference MI:0461 interaction database SH2D1B PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database SPTBN2 PLCG2 MI:0362 inference MI:0461 interaction database ZBTB7B PLCG2 MI:0362 inference MI:0461 interaction database PLXNB1 PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database PSMD3 PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database EPB41L2 PLCG2 MI:0362 inference MI:0461 interaction database WIPF1 PLCG2 MI:0362 inference MI:0461 interaction database LAT PLCG2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SPRY2 PLCG2 MI:0362 inference MI:0461 interaction database TYROBP PLCG2 MI:0362 inference MI:1106 pathways database DIAPH1 PLCG2 MI:0362 inference MI:0461 interaction database GRAP2 PLCG2 MI:0362 inference MI:1106 pathways database TOX4 PLCG2 MI:0362 inference MI:0461 interaction database FSBP PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database PTTG1 PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database EGFR PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database IGKV1D-16 PLCG2 MI:0362 inference MI:1106 pathways database IGKV1-5 PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database IGLV1-51 PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database IGHV3-23 PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database IGHV2-5 PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database IGKC PLCG2 MI:0362 inference MI:1106 pathways database IGHE PLCG2 MI:0362 inference MI:1106 pathways database IGHG1 PLCG2 MI:0362 inference MI:1106 pathways database IGHG2 PLCG2 MI:0362 inference MI:1106 pathways database IGHG3 PLCG2 MI:0362 inference MI:1106 pathways database IGHG4 PLCG2 MI:0362 inference MI:1106 pathways database IGHM PLCG2 MI:0362 inference MI:1106 pathways database IGHD PLCG2 MI:0362 inference MI:1106 pathways database CRYAB PLCG2 MI:0362 inference MI:0461 interaction database FN1 PLCG2 MI:0362 inference MI:0461 interaction database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database ERBB2 PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database TP53 PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database LCK PLCG2 MI:0362 inference MI:1106 pathways database FYN PLCG2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database IGKV4-1 PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database GSN PLCG2 MI:0362 inference MI:0461 interaction database NPM1 PLCG2 MI:0362 inference MI:0461 interaction database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database CSF1R PLCG2 MI:0362 inference MI:0461 interaction database PFN1 PLCG2 MI:0362 inference MI:0461 interaction database LYN PLCG2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database MET PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database FCGR3A PLCG2 MI:0362 inference MI:1106 pathways database CD3G PLCG2 MI:0362 inference MI:1106 pathways database IGLC6 PLCG2 MI:0362 inference MI:1106 pathways database IGLC1 PLCG2 MI:0362 inference MI:1106 pathways database IGLC2 PLCG2 MI:0362 inference MI:1106 pathways database IGLC3 PLCG2 MI:0362 inference MI:1106 pathways database UBC PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database AR PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database KIT PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database ESD PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database HSPD1 PLCG2 MI:0045 experimental interaction detection MI:0461 interaction database CD79A PLCG2 MI:0362 inference MI:1106 pathways database FCGR1A PLCG2 MI:0362 inference MI:1106 pathways database FCGR2A PLCG2 MI:0362 inference MI:1106 pathways database HLA-E PLCG2 MI:0362 inference MI:1106 pathways database TRIM27 PLCG2 MI:0362 inference MI:0461 interaction database RAC2 PLCG2 MI:0362 inference MI:0461 interaction database CD19 PLCG2 MI:0362 inference MI:1106 pathways database VAV1 PLCG2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NCK1 PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 PRKCA MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 PLCG1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 EPOR MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 ELK1 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 CD247 MI:0362 inference MI:1106 pathways database PLCG2 FLNA MI:0362 inference MI:0461 interaction database PLCG2 PAICS MI:0362 inference MI:0461 interaction database PLCG2 CBL MI:0362 inference MI:1106 pathways database PLCG2 IGHV1-2 MI:0362 inference MI:1106 pathways database PLCG2 CFL1 MI:0362 inference MI:0461 interaction database PLCG2 KLRC2 MI:0362 inference MI:1106 pathways database PLCG2 KLRK1 MI:0362 inference MI:1106 pathways database PLCG2 PIK3R1 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 SHC1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 FCER1G MI:0362 inference MI:1106 pathways database PLCG2 PFN2 MI:0362 inference MI:0461 interaction database PLCG2 IRS1 MI:0362 inference MI:0461 interaction database PLCG2 CAP2 MI:0362 inference MI:0461 interaction database PLCG2 CD79B MI:0362 inference MI:1106 pathways database PLCG2 CSK MI:0362 inference MI:0461 interaction database PLCG2 TEC MI:0362 inference MI:1106 pathways database PLCG2 WAS MI:0362 inference MI:0461 interaction database PLCG2 SYK MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 MAP2K4 MI:0362 inference MI:0461 interaction database PLCG2 VASP MI:0362 inference MI:0461 interaction database PLCG2 PLCD1 MI:0362 inference MI:1106 pathways database PLCG2 BLK MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 VAV2 MI:0362 inference MI:1106 pathways database PLCG2 ISL1 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 B2M MI:0362 inference MI:1106 pathways database PLCG2 GRB2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 RAC1 MI:0362 inference MI:1106 pathways database PLCG2 DYNLT1 MI:0362 inference MI:0461 interaction database PLCG2 SH3BP2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 MI:0362 inference MI:1106 pathways database PLCG2 SPTBN1 MI:0362 inference MI:0461 interaction database PLCG2 CAP1 MI:0362 inference MI:0461 interaction database PLCG2 PLCB3 MI:0362 inference MI:1106 pathways database PLCG2 PTPN11 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 BTK MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 SOS1 MI:0362 inference MI:1106 pathways database PLCG2 SOS2 MI:0362 inference MI:0461 interaction database PLCG2 ITK MI:0362 inference MI:1106 pathways database PLCG2 LCP2 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 PAK1 MI:0362 inference MI:1106 pathways database PLCG2 PAK2 MI:0362 inference MI:1106 pathways database PLCG2 CBLB MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 KLRD1 MI:0362 inference MI:1106 pathways database PLCG2 PLD1 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 GAB1 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 FHL2 MI:0362 inference MI:0461 interaction database PLCG2 NBR1 MI:0362 inference MI:0461 interaction database PLCG2 PRKD1 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 RALBP1 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 INF2 MI:0362 inference MI:0461 interaction database PLCG2 LHX8 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 CLEC6A MI:0362 inference MI:1106 pathways database PLCG2 BOP MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 DOK3 MI:0362 inference MI:0461 interaction database PLCG2 PHC2 MI:0362 inference MI:0461 interaction database PLCG2 KCTD17 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 SETD9 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 GABPB2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 PDCD6IP MI:0362 inference MI:0461 interaction database PLCG2 BLNK MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database PLCG2 TWIST2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 INPP5D MI:0362 inference MI:0461 interaction database PLCG2 DVL3 MI:0362 inference MI:0461 interaction database PLCG2 SH3KBP1 MI:0362 inference MI:0461,MI:1106 interaction database,pathways database PLCG2 REPS1 MI:0362 inference MI:0461 interaction database PLCG2 ASB9 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 ZNF512B MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 EPYC MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 CLEC7A MI:0362 inference MI:1106 pathways database PLCG2 BACH2 MI:0362 inference MI:0461 interaction database PLCG2 CD244 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 LAT2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 MED28 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 UCK1 MI:0362 inference MI:0461 interaction database PLCG2 TREM2 MI:0362 inference MI:1106 pathways database PLCG2 ZKSCAN7 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 EVL MI:0362 inference MI:0461 interaction database PLCG2 ERRFI1 MI:0362 inference MI:0461 interaction database PLCG2 VAV3 MI:0362 inference MI:1106 pathways database PLCG2 CLEC4E MI:0362 inference MI:1106 pathways database PLCG2 DAPP1 MI:0362 inference MI:1106 pathways database PLCG2 GAB2 MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 CD2AP MI:0362 inference MI:0461 interaction database PLCG2 RAD54B MI:0045 experimental interaction detection MI:0461 interaction database PLCG2 SCIN MI:0362 inference MI:0461 interaction database