PTM - CPLM Gene Name UniProt ID Type Position Code CD2AP Q9Y5K6 Ubiquitination 520 K CD2AP Q9Y5K6 Ubiquitination 436 K CD2AP Q9Y5K6 Ubiquitination 102 K

PTM - dbPAF Gene Name UniProt ID Position Type Species CD2AP Q9Y5K6 119 Y Homo sapiens(Human) CD2AP Q9Y5K6 159 S Homo sapiens(Human) CD2AP Q9Y5K6 180 S Homo sapiens(Human) CD2AP Q9Y5K6 188 T Homo sapiens(Human) CD2AP Q9Y5K6 189 S Homo sapiens(Human) CD2AP Q9Y5K6 224 S Homo sapiens(Human) CD2AP Q9Y5K6 229 T Homo sapiens(Human) CD2AP Q9Y5K6 231 T Homo sapiens(Human) CD2AP Q9Y5K6 232 S Homo sapiens(Human) CD2AP Q9Y5K6 233 S Homo sapiens(Human) CD2AP Q9Y5K6 234 S Homo sapiens(Human) CD2AP Q9Y5K6 236 T Homo sapiens(Human) CD2AP Q9Y5K6 256 S Homo sapiens(Human) CD2AP Q9Y5K6 260 T Homo sapiens(Human) CD2AP Q9Y5K6 262 T Homo sapiens(Human) CD2AP Q9Y5K6 264 T Homo sapiens(Human) CD2AP Q9Y5K6 361 Y Homo sapiens(Human) CD2AP Q9Y5K6 363 S Homo sapiens(Human) CD2AP Q9Y5K6 380 S Homo sapiens(Human) CD2AP Q9Y5K6 393 T Homo sapiens(Human) CD2AP Q9Y5K6 396 T Homo sapiens(Human) CD2AP Q9Y5K6 404 S Homo sapiens(Human) CD2AP Q9Y5K6 405 S Homo sapiens(Human) CD2AP Q9Y5K6 407 T Homo sapiens(Human) CD2AP Q9Y5K6 409 Y Homo sapiens(Human) CD2AP Q9Y5K6 439 T Homo sapiens(Human) CD2AP Q9Y5K6 458 S Homo sapiens(Human) CD2AP Q9Y5K6 463 S Homo sapiens(Human) CD2AP Q9Y5K6 465 T Homo sapiens(Human) CD2AP Q9Y5K6 468 T Homo sapiens(Human) CD2AP Q9Y5K6 469 S Homo sapiens(Human) CD2AP Q9Y5K6 510 S Homo sapiens(Human) CD2AP Q9Y5K6 512 T Homo sapiens(Human) CD2AP Q9Y5K6 514 S Homo sapiens(Human) CD2AP Q9Y5K6 539 T Homo sapiens(Human) CD2AP Q9Y5K6 541 Y Homo sapiens(Human) CD2AP Q9Y5K6 542 S Homo sapiens(Human) CD2AP Q9Y5K6 546 S Homo sapiens(Human) CD2AP Q9Y5K6 548 Y Homo sapiens(Human) CD2AP Q9Y5K6 550 S Homo sapiens(Human) CD2AP Q9Y5K6 551 T Homo sapiens(Human) CD2AP Q9Y5K6 553 S Homo sapiens(Human) CD2AP Q9Y5K6 554 S Homo sapiens(Human) CD2AP Q9Y5K6 556 S Homo sapiens(Human) CD2AP Q9Y5K6 561 T Homo sapiens(Human) CD2AP Q9Y5K6 565 T Homo sapiens(Human) CD2AP Q9Y5K6 582 S Homo sapiens(Human) CD2AP Q9Y5K6 67 S Homo sapiens(Human) CD2AP Q9Y5K6 80 S Homo sapiens(Human) CD2AP Q9Y5K6 86 S Homo sapiens(Human) CD2AP Q9Y5K6 87 T Homo sapiens(Human) CD2AP Q9Y5K6 88 Y Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9Y5K6 K55-ac Acetylation MFPDNFVkEIkRETE Q9Y5K6 K359-ac Acetylation PELIAAEkkyFsLKP Q9Y5K6 K360-ac Acetylation ELIAAEkkyFsLKPE Q9Y5K6 K425-ac Acetylation PPPPPIAkINGEVSS Q9Y5K6 K397-m1 Methylation KKPtPPtkASNLLRS Q9Y5K6 K495-m1 Methylation HLTANRPkMPGRRLP Q9Y5K6 S67-p Phosphorylation ETEFKDDsLPIKRER Q9Y5K6 S80-p Phosphorylation ERHGNVAsLVQRIst Q9Y5K6 S86-p Phosphorylation AsLVQRIstyGLPAG Q9Y5K6 T87-p Phosphorylation sLVQRIstyGLPAGG Q9Y5K6 Y88-p Phosphorylation LVQRIstyGLPAGGI Q9Y5K6 S180-p Phosphorylation THEAQDDsETVLAGP Q9Y5K6 S189-p Phosphorylation TVLAGPTsPIPSLGN Q9Y5K6 S224-p Phosphorylation GDIFKEGsVKLRtRt Q9Y5K6 T229-p Phosphorylation EGsVKLRtRtsssEt Q9Y5K6 T231-p Phosphorylation sVKLRtRtsssEtEE Q9Y5K6 S232-p Phosphorylation VKLRtRtsssEtEEK Q9Y5K6 S233-p Phosphorylation KLRtRtsssEtEEKK Q9Y5K6 S234-p Phosphorylation LRtRtsssEtEEKKP Q9Y5K6 T236-p Phosphorylation tRtsssEtEEKKPEK Q9Y5K6 T254-p Phosphorylation LQSLGPKtQsVEITK Q9Y5K6 S256-p Phosphorylation SLGPKtQsVEITKTD Q9Y5K6 Y361-p Phosphorylation LIAAEkkyFsLKPEE Q9Y5K6 S363-p Phosphorylation AAEkkyFsLKPEEKD Q9Y5K6 S380-p Phosphorylation STLEQKPsKPAAPQV Q9Y5K6 T393-p Phosphorylation QVPPKKPtPPtkASN Q9Y5K6 T396-p Phosphorylation PKKPtPPtkASNLLR Q9Y5K6 Y409-p Phosphorylation LRSSGTVyPKRPEKP Q9Y5K6 S458-p Phosphorylation QLPLRPKsVDFDsLt Q9Y5K6 S463-p Phosphorylation PKsVDFDsLtVRTSK Q9Y5K6 T465-p Phosphorylation sVDFDsLtVRTSKET Q9Y5K6 S510-p Phosphorylation GRFNGGHsPtHsPEK Q9Y5K6 T512-p Phosphorylation FNGGHsPtHsPEKIL Q9Y5K6 S514-p Phosphorylation GGHsPtHsPEKILKL Q9Y5K6 T539-p Phosphorylation PSELKKDtCysPKPs Q9Y5K6 Y541-p Phosphorylation ELKKDtCysPKPsVy Q9Y5K6 S542-p Phosphorylation LKKDtCysPKPsVyL Q9Y5K6 S546-p Phosphorylation tCysPKPsVyLstPs Q9Y5K6 Y548-p Phosphorylation ysPKPsVyLstPssA Q9Y5K6 S550-p Phosphorylation PKPsVyLstPssAsK Q9Y5K6 T551-p Phosphorylation KPsVyLstPssAsKA Q9Y5K6 S553-p Phosphorylation sVyLstPssAsKANT Q9Y5K6 S554-p Phosphorylation VyLstPssAsKANTT Q9Y5K6 S556-p Phosphorylation LstPssAsKANTTAF Q9Y5K6 T565-p Phosphorylation ANTTAFLtPLEIKAK Q9Y5K6 S582-p Phosphorylation TDDVKKNsLDELRAQ Q9Y5K6 K58-sm Sumoylation DNFVkEIkRETEFKD

PTM - dbPTM UniProt ID Position Code Type Resources References Q9Y5K6 88 Y Phosphorylation Swiss-Prot 1010711 15592455 Q9Y5K6 224 S Phosphorylation Swiss-Prot 1010711 18669648 Q9Y5K6 458 S Phosphorylation Swiss-Prot 1010711 18088087;18220336;18669648;19690332 Q9Y5K6 510 S Phosphorylation Swiss-Prot 1010711 17081983 Q9Y5K6 224 S Phosphorylation PhosphoELM.10011 18669648 Q9Y5K6 233 S Phosphorylation PhosphoELM.10011 18669648 Q9Y5K6 458 S Phosphorylation PhosphoELM.10011 18669648;18220336;18088087 Q9Y5K6 510 S Phosphorylation PhosphoELM.10011 17081983 Q9Y5K6 542 S Phosphorylation PhosphoELM.10011 18669648 Q9Y5K6 553 S Phosphorylation PhosphoELM.10011 18669648 Q9Y5K6 554 S Phosphorylation PhosphoELM.10011 18669648 Q9Y5K6 551 T Phosphorylation PhosphoELM.10011 18669648 Q9Y5K6 565 T Phosphorylation PhosphoELM.10011 22067460 Q9Y5K6 88 Y Phosphorylation PhosphoELM.10011 15592455 Q9Y5K6 548 Y Phosphorylation PhosphoELM.10011 16497976 Q9Y5K6 224 S Phosphorylation Phosphositeplus.1010730 18669648;20166139;21406692;22115753 Q9Y5K6 232 S Phosphorylation Phosphositeplus.1010730 19276368;20736484 Q9Y5K6 233 S Phosphorylation Phosphositeplus.1010730 19276368;20736484;20815410;21406692;22067460 Q9Y5K6 234 S Phosphorylation Phosphositeplus.1010730 20736484 Q9Y5K6 256 S Phosphorylation Phosphositeplus.1010730 20164059 Q9Y5K6 458 S Phosphorylation Phosphositeplus.1010730 18088087;18220336;18669648;19415658;19664994;19664995;19690332;20058876;20068231;20164059;20363803;21406692;21659604;22067460;22115753 Q9Y5K6 510 S Phosphorylation Phosphositeplus.1010730 17446864;19664995;20068231;20164059;20363803;20815410;21406692;22067460;22115753 Q9Y5K6 514 S Phosphorylation Phosphositeplus.1010730 17446864;20164059;20363803;21406692;22067460;22115753 Q9Y5K6 542 S Phosphorylation Phosphositeplus.1010730 18669648;19276368 Q9Y5K6 553 S Phosphorylation Phosphositeplus.1010730 19276368 Q9Y5K6 554 S Phosphorylation Phosphositeplus.1010730 19276368;20363803 Q9Y5K6 556 S Phosphorylation Phosphositeplus.1010730 20068231 Q9Y5K6 582 S Phosphorylation Phosphositeplus.1010730 20068231;20164059;20363803 Q9Y5K6 229 T Phosphorylation Phosphositeplus.1010730 20736484 Q9Y5K6 231 T Phosphorylation Phosphositeplus.1010730 20736484 Q9Y5K6 236 T Phosphorylation Phosphositeplus.1010730 19276368;20736484 Q9Y5K6 393 T Phosphorylation Phosphositeplus.1010730 22067460 Q9Y5K6 551 T Phosphorylation Phosphositeplus.1010730 22115753 Q9Y5K6 565 T Phosphorylation Phosphositeplus.1010730 19664995;22067460 Q9Y5K6 361 Y Phosphorylation Phosphositeplus.1010730 17016520;18707149;20736484 Q9Y5K6 548 Y Phosphorylation Phosphositeplus.1010730 16497976;18083107;18180459;21394647;21403953 Q9Y5K6 88 Y Phosphorylation Phosphositeplus.1010730 15592455;16497976;18083107;18180459;20007894;20090780;20736484;21403953;21447384 Q9Y5K6 189 S Phosphorylation HPRD 9.0 18452278 Q9Y5K6 224 S Phosphorylation HPRD 9.0 18669648,20166139 Q9Y5K6 233 S Phosphorylation HPRD 9.0 18669648 Q9Y5K6 363 S Phosphorylation HPRD 9.0 18212344 Q9Y5K6 458 S Phosphorylation HPRD 9.0 18669648,18088087,19664995,18212344,19651622,19664994,18452278,20068231,20058876 Q9Y5K6 510 S Phosphorylation HPRD 9.0 17322306,19664995,19651622,20068231 Q9Y5K6 514 S Phosphorylation HPRD 9.0 19651622,20068231 Q9Y5K6 542 S Phosphorylation HPRD 9.0 18669648 Q9Y5K6 553 S Phosphorylation HPRD 9.0 18669648,20068231 Q9Y5K6 554 S Phosphorylation HPRD 9.0 18669648,19651622,20068231 Q9Y5K6 556 S Phosphorylation HPRD 9.0 20068231 Q9Y5K6 582 S Phosphorylation HPRD 9.0 20068231 Q9Y5K6 231 T Phosphorylation HPRD 9.0 20068231 Q9Y5K6 260 T Phosphorylation HPRD 9.0 18767875 Q9Y5K6 262 T Phosphorylation HPRD 9.0 18767875 Q9Y5K6 264 T Phosphorylation HPRD 9.0 18767875 Q9Y5K6 512 T Phosphorylation HPRD 9.0 19651622,20068231 Q9Y5K6 551 T Phosphorylation HPRD 9.0 18669648,19651622,20068231 Q9Y5K6 565 T Phosphorylation HPRD 9.0 19664995 Q9Y5K6 88 Y Phosphorylation HPRD 9.0 15592455,16497976 Q9Y5K6 361 Y Phosphorylation HPRD 9.0 17016520,18707149 Q9Y5K6 541 Y Phosphorylation HPRD 9.0 16497976 Q9Y5K6 548 Y Phosphorylation HPRD 9.0 16497976 Q9Y5K6 224 S Phosphorylation SysPTM 1.1 18669648 Q9Y5K6 363 S Phosphorylation SysPTM 1.1 18212344 Q9Y5K6 458 S Phosphorylation SysPTM 1.1 18669648;18212344;18088087 Q9Y5K6 510 S Phosphorylation SysPTM 1.1 17081983 Q9Y5K6 361 Y Phosphorylation SysPTM 1.1 18707149

PTM - HPRD Symbol Position Code Type References CD2AP 189 S Phosphorylation 18452278 CD2AP 224 S Phosphorylation 18669648,20166139 CD2AP 231 T Phosphorylation 20068231 CD2AP 233 S Phosphorylation 18669648 CD2AP 260 T Phosphorylation 18767875 CD2AP 262 T Phosphorylation 18767875 CD2AP 264 T Phosphorylation 18767875 CD2AP 361 Y Phosphorylation 17016520,18707149 CD2AP 363 S Phosphorylation 18212344 CD2AP 458 S Phosphorylation 18669648,18088087,19664995,18212344,19651622,19664994,18452278,20068231,20058876 CD2AP 510 S Phosphorylation 17322306,19664995,19651622,20068231 CD2AP 512 T Phosphorylation 19651622,20068231 CD2AP 514 S Phosphorylation 19651622,20068231 CD2AP 541 Y Phosphorylation 16497976 CD2AP 542 S Phosphorylation 18669648 CD2AP 548 Y Phosphorylation 16497976 CD2AP 551 T Phosphorylation 18669648,19651622,20068231 CD2AP 553 S Phosphorylation 18669648,20068231 CD2AP 554 S Phosphorylation 18669648,19651622,20068231 CD2AP 556 S Phosphorylation 20068231 CD2AP 565 T Phosphorylation 19664995 CD2AP 582 S Phosphorylation 20068231 CD2AP 88 Y Phosphorylation 15592455,16497976

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9Y5K6 224 S 18669648 HTP Phosphorylation Q9Y5K6 548 Y 16497976 HTP Phosphorylation Q9Y5K6 551 T 18669648 HTP Phosphorylation Q9Y5K6 233 S 18669648 HTP Phosphorylation Q9Y5K6 458 S 18669648 HTP Phosphorylation Q9Y5K6 458 S 18220336 HTP Phosphorylation Q9Y5K6 458 S 18088087 HTP Phosphorylation Q9Y5K6 542 S 18669648 HTP Phosphorylation Q9Y5K6 553 S 18669648 HTP Phosphorylation Q9Y5K6 88 Y 15592455 HTP Phosphorylation Q9Y5K6 554 S 18669648 HTP Phosphorylation Q9Y5K6 510 S 17081983 HTP Phosphorylation Q9Y5K6 565 T 22067460 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9Y5K6 67 Phosphoserine 23186163 Q9Y5K6 80 Phosphoserine 23186163 Q9Y5K6 86 Phosphoserine 23186163 Q9Y5K6 224 Phosphoserine 21406692;23186163 Q9Y5K6 458 Phosphoserine 18088087;18220336;18669648;19690332;20068231;21406692;23186163;24275569 Q9Y5K6 463 Phosphoserine 23186163;24275569 Q9Y5K6 510 Phosphoserine 20068231;21406692;23186163 Q9Y5K6 514 Phosphoserine 21406692;23186163 Q9Y5K6 565 Phosphothreonine 23186163 Q9Y5K6 582 Phosphoserine 23186163

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type CD2AP IPI00412771 S 458 LPLRPKpSVDFDSL phosphorylation CD2AP IPI00412771 S 510 RFNGGHpSPTHSPE phosphorylation CD2AP IPI00412771 S 514 GHSPTHpSPEKILK phosphorylation CD2AP IPI00412771 S 554 YLSTPSpSASKANT phosphorylation CD2AP IPI00412771 S 556 STPSSApSKANTTA phosphorylation CD2AP IPI00412771 S 582 DDVKKNpSLDELRA phosphorylation CD2AP IPI00412771 T 439 ISSKFEpTEPVSKL phosphorylation CD2AP IPI00412771 T 512 NGGHSPpTHSPEKI phosphorylation CD2AP IPI00412771 Y 119 CKVLFEpYIPQNED phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 23607 117140 - K Ubiquitination 21890473 23607 117140 - K Ubiquitination 21963094 23607 117140 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID CD2AP Homo sapiens (Human) 520 "520,SPEKILKLPKEED" 520:21890473