PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus ASB12 SRRT 24337577 biogrid exp P P P P P P P G GP P P FGG ASB12 24337577 biogrid exp P G P ASB12 DHX38 24337577 biogrid exp P P P P P P P G GP P P GLO1 ASB12 24337577 biogrid exp P P P P P P G GP P P RBM6 ASB12 24337577 biogrid exp P P P P P P P G GP P P ASB12 CUL5 16325183 biogrid,mint,intact exp P P P P P P P G GP P P ASB12 DHX36 24337577 biogrid exp P P P P P P P G GP P P KRT8 ASB12 24337577 biogrid exp P P P P P P P G GP P SFPQ ASB12 24337577 biogrid exp P P P P P P P G GP P P CADPS2 ASB12 24337577 biogrid exp G G TUFM ASB12 24337577 biogrid exp P P P P P P P G GP P P NUDT21 ASB12 24337577 biogrid exp P P P P P P P G GP P P RBM10 ASB12 24337577 biogrid exp P P P P P P P GP P P ACTB ASB12 24337577 biogrid exp P P P P P P P G GP P P LZTR1 ASB12 20211142 biogrid exp G G PFKFB3 ASB12 24337577 biogrid exp P P P P P P P G GP P P RPL38 ASB12 24337577 biogrid exp P P P P P P G GP P P PFN2 ASB12 24337577 biogrid exp P P P P P P G GP P P AIFM1 ASB12 24337577 biogrid exp P P P P P P P G GP P P MYH10 ASB12 24337577 biogrid exp P P P P P P G GP P P RCN2 ASB12 24337577 biogrid exp P G G P P TCEB1 ASB12 24337577 biogrid exp G G PFN1 ASB12 24337577 biogrid exp P P P P P P P G GP P P TCEB2 ASB12 24337577 biogrid exp G G CKB ASB12 24337577 biogrid exp P G G P ASB12 RNF7 16325183 biogrid,mint,intact exp P P P P P P G GP P P PRDX6 ASB12 24337577 biogrid exp P P P P P P P G GP P P MTHFD1L ASB12 24337577 biogrid exp P P P P P P P P P P NFE2 ASB12 ortho P P P P P P P P P P HOXA2 ASB12 ortho P P P P MYOCD ASB12 ortho P P P P P P P GP P P ANKDD1A ASB12 23023127 pred P P G P P ADRBK1 ASB12 23023127 pred P P P P P P P G GP P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8WXK4 cosedimentation in solution 16325183 association C 5 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 in vivo 16325183 - C 7 Q8WXK4 Q93034 anti tag coimmunoprecipitation 16325183 physical association X 2 Q9UBF6 Q8WXK4 anti tag coimmunoprecipitation 16325183 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B ACTB ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309879 prey bait PFN2 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309878 prey bait MYH10 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309884 prey bait RCN2 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309899 prey bait CADPS2 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309891 prey bait KRT8 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309898 prey bait ASB12 SRRT MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309888 bait prey RPL38 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309885 prey bait SFPQ ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309883 prey bait CKB ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309893 prey bait DHX38 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309882 prey bait ASB12 RNF7 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo)|MI:0493(in vivo) 16325183 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|-|- (intact)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0468(hprd)|MI:0468(hprd) UniProt_82818|BIOGRID_124955|MINT_76437|MINT_45871|HPRD_39813|HPRD_39817 bait|bait|bait|bait|-|- prey|prey|prey|prey|-|- AIFM1 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309900 prey bait PFKFB3 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309895 prey bait MTHFD1L ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309889 prey bait RBM6 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309890 prey bait TCEB1 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309880 prey bait CUL5 ASB12 MI:0493(in vivo)|MI:0493(in vivo)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 16325183 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|-|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0468(hprd)|MI:0468(hprd)|(intact)|(biogrid)|MI:0471(mint)|MI:0471(mint) HPRD_39813|HPRD_39817|UniProt_82819|BIOGRID_124954|MINT_76438|MINT_45872 -|-|prey|prey|prey|prey -|-|bait|bait|bait|bait TCEB2 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309881 prey bait LZTR1 ASB12 MI:0018(two hybrid) 20211142 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_128783 bait prey NUDT21 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309896 prey bait RBM10 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309886 prey bait PRDX6 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309887 prey bait TUFM ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309892 prey bait PFN1 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309877 prey bait GLO1 ASB12 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309901 prey bait ASB12 DHX36 MI:0004(affinity chromatography technology) 24337577 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_309894 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8WXK4 Q8N653 ASB12 LZTR1 0.183 20211142 Q93034 Q8WXK4 CUL5 ASB12 0.376 16325183 Q9UBF6 Q8WXK4 RNF7 ASB12 0.376 16325183 Q8WXK4 O43809 ASB12 NUDT21 0.126 24337577 Q8WXK4 P35080 ASB12 PFN2 0.126 24337577 Q8WXK4 P05787 ASB12 KRT8 0.126 24337577 Q8WXK4 O95831 ASB12 AIFM1 0.126 24337577 Q8WXK4 P02679 ASB12 FGG 0.126 24337577 Q8WXK4 P23246 ASB12 SFPQ 0.126 24337577 Q8WXK4 P12277 ASB12 CKB 0.126 24337577 Q8WXK4 P07737 ASB12 PFN1 0.126 24337577 Q8WXK4 Q15369 ASB12 TCEB1 0.126 24337577 Q8WXK4 P30041 ASB12 PRDX6 0.126 24337577 Q8WXK4 Q14257 ASB12 RCN2 0.126 24337577 Q8WXK4 P63173 ASB12 RPL38 0.126 24337577 Q8WXK4 P60709 ASB12 ACTB 0.126 24337577 Q8WXK4 P35580 ASB12 MYH10 0.126 24337577 Q8WXK4 P49411 ASB12 TUFM 0.126 24337577 Q8WXK4 P78332 ASB12 RBM6 0.126 24337577 Q8WXK4 Q04760 ASB12 GLO1 0.126 24337577 Q8WXK4 P98175 ASB12 RBM10 0.126 24337577 Q9H2U1 Q8WXK4 DHX36 ASB12 0.126 24337577 Q8WXK4 Q6UB35 ASB12 MTHFD1L 0.126 24337577 Q8WXK4 Q15370 ASB12 TCEB2 0.126 24337577 Q8WXK4 Q16875 ASB12 PFKFB3 0.126 24337577 Q9BXP5 Q8WXK4 SRRT ASB12 0.126 24337577 Q8WXK4 Q86UW7 ASB12 CADPS2 0.126 24337577 Q92620 Q8WXK4 DHX38 ASB12 0.126 24337577

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 HOXA2 ASB12 MI:0362 inference MI:0461 interaction database NUDT21 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database AIFM1 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database FGG ASB12 MI:0045 experimental interaction detection MI:0461 interaction database KRT8 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database PFN1 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database CKB ASB12 MI:0045 experimental interaction detection MI:0461 interaction database HOXB2 ASB12 MI:0362 inference MI:0461 interaction database SFPQ ASB12 MI:0045 experimental interaction detection MI:0461 interaction database PRDX6 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database PFN2 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database MYH10 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database TUFM ASB12 MI:0045 experimental interaction detection MI:0461 interaction database ACTB ASB12 MI:0045 experimental interaction detection MI:0461 interaction database RPL38 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database RBM6 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database RBM10 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database GLO1 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database RCN2 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database TCEB1 ASB12 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database TCEB2 ASB12 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database NFE2 ASB12 MI:0362 inference MI:0461 interaction database PFKFB3 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database MTHFD1L ASB12 MI:0045 experimental interaction detection MI:0461 interaction database CADPS2 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database MYOCD ASB12 MI:0362 inference MI:0461 interaction database LZTR1 ASB12 MI:0045 experimental interaction detection MI:0461 interaction database ASB12 DHX38 MI:0045 experimental interaction detection MI:0461 interaction database ASB12 CUL5 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database ASB12 SRRT MI:0045 experimental interaction detection MI:0461 interaction database ASB12 DHX36 MI:0045 experimental interaction detection MI:0461 interaction database ASB12 RNF7 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database