PTM - CPLM Gene Name UniProt ID Type Position Code PJA2; KIAA0438; RNF131 O43164 Acetylation 46 K PJA2; KIAA0438; RNF131 O43164 Ubiquitination 320 K PJA2; KIAA0438; RNF131 O43164 Ubiquitination 339 K PJA2; KIAA0438; RNF131 O43164 Ubiquitination 667 K PJA2; KIAA0438; RNF131 O43164 Ubiquitination 268 K PJA2; KIAA0438; RNF131 O43164 Ubiquitination 317 K

PTM - dbPAF Gene Name UniProt ID Position Type Species PJA2; KIAA0438; RNF131 O43164 134 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 167 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 168 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 193 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 196 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 212 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 216 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 235 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 241 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 242 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 246 T Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 253 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 28 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 282 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 30 T Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 308 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 309 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 323 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 324 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 325 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 342 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 355 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 357 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 367 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 380 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 381 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 385 T Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 389 T Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 396 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 4 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 42 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 428 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 429 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 432 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 44 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 452 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 453 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 454 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 457 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 460 T Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 494 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 576 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 596 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 63 Y Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 76 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 77 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 79 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 80 S Homo sapiens(Human) PJA2; KIAA0438; RNF131 O43164 88 S Homo sapiens(Human)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA O43164 K46-ac Acetylation RHAyVsFkPCMTRHE O43164 K46-m1 Methylation RHAyVsFkPCMTRHE O43164 Y4-p Phosphorylation ____MSQyTEKEPAA O43164 Y28-p Phosphorylation WPKPAGGyQtITGRR O43164 T30-p Phosphorylation KPAGGyQtITGRRYG O43164 Y42-p Phosphorylation RYGRRHAyVsFkPCM O43164 S44-p Phosphorylation GRRHAyVsFkPCMTR O43164 Y63-p Phosphorylation LGRAGDDyEVLELDD O43164 S76-p Phosphorylation DDVPKENsSGSsPLD O43164 S80-p Phosphorylation KENsSGSsPLDQVDS O43164 S134-p Phosphorylation EGRDTLGsSTNLHNH O43164 S167-p Phosphorylation IALVHTDsyDPDGKH O43164 Y168-p Phosphorylation ALVHTDsyDPDGKHG O43164 Y193-p Phosphorylation EVVEGSRyQEsLGNT O43164 S196-p Phosphorylation EGSRyQEsLGNTVFE O43164 Y212-p Phosphorylation ENREAEAyTGLsPPV O43164 S216-p Phosphorylation AEAyTGLsPPVPSFN O43164 S235-p Phosphorylation DEFEELDsVPLVKSS O43164 T246-p Phosphorylation VKSSAGDtEFVHQNs O43164 S253-p Phosphorylation tEFVHQNsQEIQRSS O43164 S282-p Phosphorylation QERQTEHsPEDAACG O43164 S308-p Phosphorylation DREKNHGssPEQVVR O43164 S309-p Phosphorylation REKNHGssPEQVVRP O43164 S323-p Phosphorylation PkVRkLIssSQVDQE O43164 S324-p Phosphorylation kVRkLIssSQVDQET O43164 S342-p Phosphorylation RHEAkQRsVQRWREA O43164 Y367-p Phosphorylation LLIKCEEyDGEHDCM O43164 Y380-p Phosphorylation CMFLDPPysRVItQR O43164 S381-p Phosphorylation MFLDPPysRVItQRE O43164 T385-p Phosphorylation PPysRVItQREtENN O43164 T389-p Phosphorylation RVItQREtENNQMTs O43164 S396-p Phosphorylation tENNQMTsESGATAG O43164 S428-p Phosphorylation LYDKDEDssECsDGE O43164 S429-p Phosphorylation YDKDEDssECsDGEW O43164 S432-p Phosphorylation DEDssECsDGEWSAS O43164 S452-p Phosphorylation SGTEKDQsssDEsWE O43164 S453-p Phosphorylation GTEKDQsssDEsWEt O43164 S454-p Phosphorylation TEKDQsssDEsWEtL O43164 S457-p Phosphorylation DQsssDEsWEtLPGK O43164 T460-p Phosphorylation ssDEsWEtLPGKDEN O43164 S596-p Phosphorylation TALAHLEsLAVDVEV O43164 K268-ub Ubiquitination QDEMVSTkQQNNTSQ O43164 K317-ub Ubiquitination PEQVVRPkVRkLIss O43164 K320-ub Ubiquitination VVRPkVRkLIssSQV O43164 K339-ub Ubiquitination GFNRHEAkQRsVQRW O43164 K667-ub Ubiquitination CVSIWLQkSGTCPVC

PTM - dbPTM UniProt ID Position Code Type Resources References O43164 323 S Phosphorylation Swiss-Prot 1010711 19690332 O43164 342 S Phosphorylation Swiss-Prot 1010711 21423175 O43164 380 Y Phosphorylation Swiss-Prot 1010711 17081983 O43164 381 S Phosphorylation Swiss-Prot 1010711 17081983 O43164 385 T Phosphorylation Swiss-Prot 1010711 17081983 O43164 389 T Phosphorylation Swiss-Prot 1010711 21423175 O43164 428 S Phosphorylation Swiss-Prot 1010711 17081983 O43164 429 S Phosphorylation Swiss-Prot 1010711 17081983 O43164 432 S Phosphorylation Swiss-Prot 1010711 17081983 O43164 2 S Acetylation Swiss-Prot 1010711 - O43164 323 S Phosphorylation PhosphoELM.10011 18669648 O43164 381 S Phosphorylation PhosphoELM.10011 17081983 O43164 428 S Phosphorylation PhosphoELM.10011 17081983 O43164 429 S Phosphorylation PhosphoELM.10011 17081983 O43164 432 S Phosphorylation PhosphoELM.10011 17081983 O43164 385 T Phosphorylation PhosphoELM.10011 17081983 O43164 380 Y Phosphorylation PhosphoELM.10011 17081983 O43164 268 K Ubiquitylation Phosphositeplus.1010730 20972266;21906983 O43164 320 K Ubiquitylation Phosphositeplus.1010730 21890473;21906983 O43164 339 K Ubiquitylation Phosphositeplus.1010730 21890473 O43164 667 K Ubiquitylation Phosphositeplus.1010730 21890473 O43164 235 S Phosphorylation Phosphositeplus.1010730 19664994 O43164 253 S Phosphorylation Phosphositeplus.1010730 21406692 O43164 309 S Phosphorylation Phosphositeplus.1010730 19276368;20815410;21406692 O43164 323 S Phosphorylation Phosphositeplus.1010730 18669648;19690332;21406692 O43164 342 S Phosphorylation Phosphositeplus.1010730 21423175 O43164 381 S Phosphorylation Phosphositeplus.1010730 17081983 O43164 452 S Phosphorylation Phosphositeplus.1010730 20363803 O43164 453 S Phosphorylation Phosphositeplus.1010730 20363803 O43164 454 S Phosphorylation Phosphositeplus.1010730 20363803 O43164 457 S Phosphorylation Phosphositeplus.1010730 20363803 O43164 385 T Phosphorylation Phosphositeplus.1010730 17081983 O43164 389 T Phosphorylation Phosphositeplus.1010730 21423175 O43164 380 Y Phosphorylation Phosphositeplus.1010730 17081983 O43164 63 Y Phosphorylation Phosphositeplus.1010730 20007894;20562096 O43164 79 S Phosphorylation HPRD 9.0 20068231 O43164 235 S Phosphorylation HPRD 9.0 19664994 O43164 309 S Phosphorylation HPRD 9.0 19651622,20068231 O43164 323 S Phosphorylation HPRD 9.0 18669648 O43164 4 Y Phosphorylation HPRD 9.0 20068231 O43164 308 S Phosphorylation SysPTM 1.1 17081983 O43164 381 S Phosphorylation SysPTM 1.1 17081983 O43164 428 S Phosphorylation SysPTM 1.1 17081983 O43164 429 S Phosphorylation SysPTM 1.1 17081983 O43164 432 S Phosphorylation SysPTM 1.1 17081983 O43164 385 T Phosphorylation SysPTM 1.1 17081983 O43164 380 Y Phosphorylation SysPTM 1.1 17081983

PTM - HPRD Symbol Position Code Type References PJA2 235 S Phosphorylation 19664994 PJA2 309 S Phosphorylation 19651622,20068231 PJA2 323 S Phosphorylation 18669648 PJA2 4 Y Phosphorylation 20068231 PJA2 79 S Phosphorylation 20068231

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type O43164 428 S 17081983 HTP Phosphorylation O43164 429 S 17081983 HTP Phosphorylation O43164 385 T 17081983 HTP Phosphorylation O43164 323 S 18669648 HTP Phosphorylation O43164 380 Y 17081983 HTP Phosphorylation O43164 432 S 17081983 HTP Phosphorylation O43164 381 S 17081983 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs O43164 196 Phosphoserine 23186163 O43164 246 Phosphothreonine 24275569 O43164 253 Phosphoserine 23186163 O43164 309 Phosphoserine 21406692;23186163 O43164 323 Phosphoserine 19690332 O43164 342 Phosphoserine; by PKA 21423175 O43164 389 Phosphothreonine; by PKA 21423175 O43164 432 Phosphoserine 17081983

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type PJA2 IPI00006557 S 309 EKNHGSpSPEQVVR phosphorylation PJA2 IPI00006557 S 381 FLDPPYpSRVITQR phosphorylation PJA2 IPI00006557 S 428 YDKDEDpSSECSDG phosphorylation PJA2 IPI00006557 S 429 DKDEDSpSECSDGE phosphorylation PJA2 IPI00006557 S 432 EDSSECpSDGEWSA phosphorylation PJA2 IPI00006557 T 385 PYSRVIpTQRETEN phosphorylation PJA2 IPI00006557 Y 380 MFLDPPpYSRVITQ phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 9867 115200 - K Ubiquitination 16196087 9867 115200 - K Ubiquitination 18781797 9867 115200 - K Ubiquitination 21987572 9867 115200 - K Ubiquitination 20972266 9867 115200 - K Ubiquitination 21139048 9867 115200 - K Ubiquitination 21890473 9867 115200 - K Ubiquitination 21906983 9867 115200 - K Ubiquitination 22505724 9867 115200 - K Ubiquitination 21963094 9867 115200 - K Ubiquitination 23000965 9867 115200 - K Ubiquitination 24816145

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID PJA2 Homo sapiens (Human) 268 "268,DEMVSTKQQNNTS" 268:20972266 PJA2 Homo sapiens (Human) 339; 320; 647 "339,FNRHEAKQRSVQR; 320,VRPKVRKLISSSQ; 647,VSIWLQKSGTCPV" 339:21890473; 320:21890473; 647:21890473 PJA2 Homo sapiens (Human) 339; 320; 647; 268 "339,FNRHEAKQRSVQR; 320,VRPKVRKLISSSQ; 647,VSIWLQKSGTCPV; 268,DEMVSTKQQNNTS" "339:21890473; 320:21890473,21906983; 647:21890473; 268:21906983" PJA2 Homo sapiens (Human) 339; 320; 667; 268 "339,FNRHEAKQRSVQR; 320,VRPKVRKLISSSQ; 667,VSIWLQKSGTCPV; 268,DEMVSTKQQNNTS" "339:21890473; 320:21890473,21906983; 667:21890473; 268:21906983"