Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 6 33283358 33283358 + Missense_Mutation SNP C C A TCGA-OR-A5KB-01A-11D-A30A-10 TCGA-OR-A5KB-11A-11D-A30A-10 g.chr6:33283358C>A c.1336G>T c.(1336-1338)Ggg>Tgg p.G446W ACC 6 33283545 33283545 + Missense_Mutation SNP G G T TCGA-PK-A5HB-01A-11D-A29I-10 TCGA-PK-A5HB-11A-11D-A29L-10 g.chr6:33283545G>T c.1149C>A c.(1147-1149)gaC>gaA p.D383E BLCA 6 33282841 33282841 + Missense_Mutation SNP G G C TCGA-FD-A6TB-01A-12D-A339-08 TCGA-FD-A6TB-10A-21D-A339-08 g.chr6:33282841G>C c.1853C>G c.(1852-1854)cCc>cGc p.P618R BLCA 6 33282940 33282940 + Missense_Mutation SNP G G A TCGA-XF-A9SY-01A-21D-A42E-08 TCGA-XF-A9SY-10A-01D-A42H-08 g.chr6:33282940G>A c.1754C>T c.(1753-1755)tCc>tTc p.S585F BLCA 6 33283128 33283128 + Missense_Mutation SNP G G C TCGA-E5-A4U1-01A-11D-A31L-08 TCGA-E5-A4U1-10B-01D-A31J-08 g.chr6:33283128G>C c.1566C>G c.(1564-1566)ttC>ttG p.F522L BLCA 6 33283235 33283235 + Silent SNP G G A TCGA-DK-A1A3-01A-11D-A13W-08 TCGA-DK-A1A3-10A-01D-A13W-08 g.chr6:33283235G>A c.1459C>T c.(1459-1461)Ctg>Ttg p.L487L BLCA 6 33283239 33283239 + Missense_Mutation SNP G G C TCGA-DK-AA75-01A-11D-A391-08 TCGA-DK-AA75-10A-01D-A394-08 g.chr6:33283239G>C c.1455C>G c.(1453-1455)atC>atG p.I485M BLCA 6 33283453 33283453 + Missense_Mutation SNP C C G TCGA-FD-A5C1-01A-11D-A289-08 TCGA-FD-A5C1-10A-01D-A289-08 g.chr6:33283453C>G c.1241G>C c.(1240-1242)cGa>cCa p.R414P BLCA 6 33283454 33283454 + Missense_Mutation SNP G G C TCGA-S5-A6DX-01A-11D-A31L-08 TCGA-S5-A6DX-10A-01D-A31J-08 g.chr6:33283454G>C c.1240C>G c.(1240-1242)Cga>Gga p.R414G BLCA 6 33283569 33283569 + Silent SNP G G A TCGA-GD-A2C5-01A-12D-A17V-08 TCGA-GD-A2C5-10A-01D-A17V-08 g.chr6:33283569G>A c.1125C>T c.(1123-1125)gtC>gtT p.V375V BLCA 6 33283569 33283569 + Silent SNP G G C TCGA-XF-AAMF-01A-21D-A42E-08 TCGA-XF-AAMF-10A-01D-A42H-08 g.chr6:33283569G>C c.1125C>G c.(1123-1125)gtC>gtG p.V375V BLCA 6 33283600 33283600 + Missense_Mutation SNP C C T TCGA-E7-A6ME-01A-22D-A32B-08 TCGA-E7-A6ME-10B-01D-A329-08 g.chr6:33283600C>T c.1094G>A c.(1093-1095)aGt>aAt p.S365N BLCA 6 33283928 33283928 + Missense_Mutation SNP T T C TCGA-UY-A8OB-01A-12D-A42E-08 TCGA-UY-A8OB-11A-12D-A42H-08 g.chr6:33283928T>C c.766A>G c.(766-768)Aag>Gag p.K256E BLCA 6 33284043 33284043 + Missense_Mutation SNP G G C TCGA-UY-A9PB-01A-11D-A38G-08 TCGA-UY-A9PB-10A-01D-A38J-08 g.chr6:33284043G>C c.651C>G c.(649-651)ttC>ttG p.F217L BLCA 6 33284067 33284067 + Silent SNP G G A TCGA-FD-A3SS-01A-12D-A22Z-08 TCGA-FD-A3SS-10A-01D-A22Z-08 g.chr6:33284067G>A c.627C>T c.(625-627)ttC>ttT p.F209F BLCA 6 33284074 33284074 + Missense_Mutation SNP T T C TCGA-BT-A2LB-01A-11D-A18F-08 TCGA-BT-A2LB-10A-01D-A18F-08 g.chr6:33284074T>C c.620A>G c.(619-621)aAc>aGc p.N207S BLCA 6 33284271 33284271 + Missense_Mutation SNP G G C TCGA-XF-A9SM-01A-11D-A42E-08 TCGA-XF-A9SM-10A-01D-A42H-08 g.chr6:33284271G>C c.423C>G c.(421-423)gaC>gaG p.D141E BLCA 6 33284343 33284343 + Silent SNP G G A TCGA-XF-A9T5-01A-11D-A42E-08 TCGA-XF-A9T5-10A-01D-A42H-08 g.chr6:33284343G>A c.351C>T c.(349-351)ctC>ctT p.L117L BLCA 6 33284382 33284382 + Silent SNP G G A TCGA-CU-A0YR-01A-12D-A10S-08 TCGA-CU-A0YR-10A-01D-A10S-08 g.chr6:33284382G>A c.312C>T c.(310-312)gcC>gcT p.A104A BLCA 6 33284430 33284430 + Silent SNP G G C TCGA-DK-A1A3-01A-11D-A13W-08 TCGA-DK-A1A3-10A-01D-A13W-08 g.chr6:33284430G>C c.264C>G c.(262-264)ctC>ctG p.L88L BLCA 6 33284441 33284441 + Missense_Mutation SNP G G C TCGA-E5-A4U1-01A-11D-A31L-08 TCGA-E5-A4U1-10B-01D-A31J-08 g.chr6:33284441G>C c.253C>G c.(253-255)Cag>Gag p.Q85E BLCA 6 33284496 33284496 + Silent SNP C C T TCGA-FD-A3SR-01A-11D-A22Z-08 TCGA-FD-A3SR-10A-01D-A22Z-08 g.chr6:33284496C>T c.198G>A c.(196-198)cgG>cgA p.R66R BRCA 6 33282945 33282945 + Frame_Shift_Del DEL C C - TCGA-BH-A0AV-01A-31D-A10Y-09 TCGA-BH-A0AV-10A-01D-A110-09 g.chr6:33282945delC c.1749delG c.(1747-1749)gggfs p.G583fs BRCA 6 33283446 33283446 + Silent SNP G G C TCGA-BH-A0B6-01A-11D-A19Y-09 TCGA-BH-A0B6-10A-01D-A19Y-09 g.chr6:33283446G>C c.1248C>G c.(1246-1248)ctC>ctG p.L416L BRCA 6 33283626 33283626 + Silent SNP G G A TCGA-E2-A1IN-01A-11D-A13L-09 TCGA-E2-A1IN-10A-01D-A188-09 g.chr6:33283626G>A c.1068C>T c.(1066-1068)ctC>ctT p.L356L BRCA 6 33284027 33284027 + Missense_Mutation SNP C C T TCGA-BH-A0E1-01A-11W-A071-09 TCGA-BH-A0E1-10A-01W-A071-09 g.chr6:33284027C>T c.667G>A c.(667-669)Gag>Aag p.E223K BRCA 6 33284490 33284490 + Silent SNP G G A TCGA-BH-A0B6-01A-11D-A19Y-09 TCGA-BH-A0B6-10A-01D-A19Y-09 g.chr6:33284490G>A c.204C>T c.(202-204)ttC>ttT p.F68F BRCA 6 33284663 33284663 + Frame_Shift_Del DEL C C - TCGA-A2-A0EU-01A-22W-A071-09 TCGA-A2-A0EU-10A-01W-A071-09 g.chr6:33284663delC c.31delG c.(31-33)gcafs p.A12fs CESC 6 33283917 33283917 + Silent SNP C C T TCGA-FU-A3YQ-01A-11D-A22X-09 TCGA-FU-A3YQ-10A-01D-A22X-09 g.chr6:33283917C>T c.777G>A c.(775-777)ctG>ctA p.L259L CESC 6 33284082 33284082 + Silent SNP G G A TCGA-EK-A2RJ-01A-11D-A18J-09 TCGA-EK-A2RJ-10A-01D-A18J-09 g.chr6:33284082G>A c.612C>T c.(610-612)agC>agT p.S204S COAD 6 33283201 33283201 + Missense_Mutation SNP C C T TCGA-AA-3984-01A-02W-0995-10 TCGA-AA-3984-10A-01W-0999-10 g.chr6:33283201C>T c.1493G>A c.(1492-1494)aGc>aAc p.S498N COAD 6 33283467 33283467 + Frame_Shift_Del DEL G G - TCGA-F4-6856-01A-11D-1924-10 TCGA-F4-6856-10A-01D-1924-10 g.chr6:33283467delG c.1227delC c.(1225-1227)cccfs p.P409fs COAD 6 33283645 33283645 + Frame_Shift_Del DEL C C - TCGA-AD-6889-01A-11D-1924-10 TCGA-AD-6889-10A-01D-1924-10 g.chr6:33283645delC c.1049delG c.(1048-1050)ggafs p.G351fs COAD 6 33283914 33283914 + Missense_Mutation SNP C C A TCGA-AA-3713-01A-21D-1719-10 TCGA-AA-3713-11A-01D-1719-10 g.chr6:33283914C>A c.780G>T c.(778-780)gaG>gaT p.E260D COAD 6 33284128 33284128 + Missense_Mutation SNP G G A TCGA-CK-5916-01A-11D-1650-10 TCGA-CK-5916-10A-01D-1650-10 g.chr6:33284128G>A c.566C>T c.(565-567)gCg>gTg p.A189V COAD 6 33284168 33284168 + Missense_Mutation SNP C C T TCGA-AA-3492-01A-01D-1408-10 TCGA-AA-3492-11A-01D-1408-10 g.chr6:33284168C>T c.526G>A c.(526-528)Ggg>Agg p.G176R COAD 6 33284506 33284506 + Missense_Mutation SNP A A G TCGA-CK-6746-01A-11D-1835-10 TCGA-CK-6746-10A-01D-1835-10 g.chr6:33284506A>G c.188T>C c.(187-189)gTg>gCg p.V63A COAD 6 33284545 33284545 + Missense_Mutation SNP T T C TCGA-AY-6386-01A-21D-1719-10 TCGA-AY-6386-10A-01D-1719-10 g.chr6:33284545T>C c.149A>G c.(148-150)cAg>cGg p.Q50R COAD 6 33284546 33284546 + Missense_Mutation SNP G G T TCGA-CK-4950-01A-01D-1719-10 TCGA-CK-4950-10A-01D-1719-10 g.chr6:33284546G>T c.148C>A c.(148-150)Cag>Aag p.Q50K COADREAD 6 33283201 33283201 + Missense_Mutation SNP C C T TCGA-AA-3984-01A-02W-0995-10 TCGA-AA-3984-10A-01W-0999-10 g.chr6:33283201C>T c.1493G>A c.(1492-1494)aGc>aAc p.S498N COADREAD 6 33283467 33283467 + Frame_Shift_Del DEL G G - TCGA-F4-6856-01A-11D-1924-10 TCGA-F4-6856-10A-01D-1924-10 g.chr6:33283467delG c.1227delC c.(1225-1227)cccfs p.P409fs COADREAD 6 33283645 33283645 + Frame_Shift_Del DEL C C - TCGA-AD-6889-01A-11D-1924-10 TCGA-AD-6889-10A-01D-1924-10 g.chr6:33283645delC c.1049delG c.(1048-1050)ggafs p.G351fs COADREAD 6 33283914 33283914 + Missense_Mutation SNP C C A TCGA-AA-3713-01A-21D-1719-10 TCGA-AA-3713-11A-01D-1719-10 g.chr6:33283914C>A c.780G>T c.(778-780)gaG>gaT p.E260D COADREAD 6 33284128 33284128 + Missense_Mutation SNP G G A TCGA-CK-5916-01A-11D-1650-10 TCGA-CK-5916-10A-01D-1650-10 g.chr6:33284128G>A c.566C>T c.(565-567)gCg>gTg p.A189V COADREAD 6 33284168 33284168 + Missense_Mutation SNP C C T TCGA-AA-3492-01A-01D-1408-10 TCGA-AA-3492-11A-01D-1408-10 g.chr6:33284168C>T c.526G>A c.(526-528)Ggg>Agg p.G176R COADREAD 6 33284506 33284506 + Missense_Mutation SNP A A G TCGA-CK-6746-01A-11D-1835-10 TCGA-CK-6746-10A-01D-1835-10 g.chr6:33284506A>G c.188T>C c.(187-189)gTg>gCg p.V63A COADREAD 6 33284545 33284545 + Missense_Mutation SNP T T C TCGA-AY-6386-01A-21D-1719-10 TCGA-AY-6386-10A-01D-1719-10 g.chr6:33284545T>C c.149A>G c.(148-150)cAg>cGg p.Q50R COADREAD 6 33284546 33284546 + Missense_Mutation SNP G G T TCGA-CK-4950-01A-01D-1719-10 TCGA-CK-4950-10A-01D-1719-10 g.chr6:33284546G>T c.148C>A c.(148-150)Cag>Aag p.Q50K DLBC 6 33283277 33283277 + Missense_Mutation SNP C C G TCGA-FF-8043-01A-11D-2210-10 TCGA-FF-8043-10A-01D-2210-10 g.chr6:33283277C>G c.1417G>C c.(1417-1419)Gtc>Ctc p.V473L DLBC 6 33283945 33283945 + Missense_Mutation SNP C C G TCGA-G8-6324-01A-11D-2210-10 TCGA-G8-6324-10A-01D-2210-10 g.chr6:33283945C>G c.749G>C c.(748-750)gGa>gCa p.G250A ESCA 6 33283128 33283128 + Silent SNP G G A TCGA-LN-A9FP-01A-31D-A387-09 TCGA-LN-A9FP-10A-01D-A38A-09 g.chr6:33283128G>A c.1566C>T c.(1564-1566)ttC>ttT p.F522F ESCA 6 33283669 33283669 + Frame_Shift_Del DEL C C - TCGA-L5-A4OI-01A-11D-A27G-09 TCGA-L5-A4OI-11A-11D-A27G-09 g.chr6:33283669delC c.1025delG c.(1024-1026)ggtfs p.G342fs ESCA 6 33284415 33284415 + Silent SNP G G A TCGA-LN-A4A5-01A-21D-A27G-09 TCGA-LN-A4A5-10A-01D-A27G-09 g.chr6:33284415G>A c.279C>T c.(277-279)tcC>tcT p.S93S ESCA 6 33284640 33284640 + Silent SNP C C A TCGA-R6-A8WC-01A-11D-A37C-09 TCGA-R6-A8WC-10A-01D-A37F-09 g.chr6:33284640C>A c.54G>T c.(52-54)tcG>tcT p.S18S HNSC 6 33282955 33282955 + Missense_Mutation SNP G G A TCGA-IQ-A61K-01A-11D-A30E-08 TCGA-IQ-A61K-10A-01D-A30H-08 g.chr6:33282955G>A c.1739C>T c.(1738-1740)aCt>aTt p.T580I HNSC 6 33283004 33283005 + Frame_Shift_Del DEL CA CA - TCGA-CN-5369-01A-01D-1434-08 TCGA-CN-5369-10A-01D-1434-08 g.chr6:33283004_33283005delCA c.1689_1690delTG c.(1687-1692)tgtgagfs p.CE563fs HNSC 6 33283037 33283037 + Frame_Shift_Del DEL G G - TCGA-CQ-A4CG-01A-11D-A25Y-08 TCGA-CQ-A4CG-10A-01D-A25Y-08 g.chr6:33283037delG c.1657delC c.(1657-1659)cgafs p.R553fs HNSC 6 33283298 33283298 + Missense_Mutation SNP C C A TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr6:33283298C>A c.1396G>T c.(1396-1398)Gtg>Ttg p.V466L HNSC 6 33283438 33283442 + Frame_Shift_Del DEL AAGGG AAGGG - TCGA-CQ-5334-01A-01D-1683-08 TCGA-CQ-5334-10A-01D-1683-08 g.chr6:33283438_33283442delAAGGG c.1252_1256delCCCTT c.(1252-1257)cccttgfs p.PL418fs HNSC 6 33283441 33283441 + Missense_Mutation SNP G G A TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr6:33283441G>A c.1253C>T c.(1252-1254)cCc>cTc p.P418L HNSC 6 33283442 33283442 + Missense_Mutation SNP G G T TCGA-TN-A7HL-01A-11D-A34J-08 TCGA-TN-A7HL-10A-01D-A34M-08 g.chr6:33283442G>T c.1252C>A c.(1252-1254)Ccc>Acc p.P418T HNSC 6 33283477 33283477 + Missense_Mutation SNP G G A TCGA-CN-6022-01A-21D-1683-08 TCGA-CN-6022-10A-01D-1683-08 g.chr6:33283477G>A c.1217C>T c.(1216-1218)tCc>tTc p.S406F HNSC 6 33283609 33283609 + Missense_Mutation SNP C C T TCGA-QK-A6IH-01A-11D-A31L-08 TCGA-QK-A6IH-10A-01D-A31J-08 g.chr6:33283609C>T c.1085G>A c.(1084-1086)cGt>cAt p.R362H HNSC 6 33283712 33283712 + Missense_Mutation SNP G G C TCGA-CR-7374-01A-11D-2012-08 TCGA-CR-7374-10A-01D-2013-08 g.chr6:33283712G>C c.982C>G c.(982-984)Ctg>Gtg p.L328V HNSC 6 33283758 33283758 + Silent SNP C C A TCGA-BA-4078-01A-01D-1434-08 TCGA-BA-4078-10A-01D-1434-08 g.chr6:33283758C>A c.936G>T c.(934-936)ctG>ctT p.L312L HNSC 6 33283873 33283873 + Missense_Mutation SNP G G A TCGA-CV-6933-01A-11D-1912-08 TCGA-CV-6933-10A-01D-1912-08 g.chr6:33283873G>A c.821C>T c.(820-822)gCa>gTa p.A274V HNSC 6 33284041 33284041 + Missense_Mutation SNP G G A TCGA-CV-7427-01A-11D-2078-08 TCGA-CV-7427-10A-01D-2078-08 g.chr6:33284041G>A c.653C>T c.(652-654)tCa>tTa p.S218L HNSC 6 33284113 33284113 + Missense_Mutation SNP G G T TCGA-CV-7433-01A-11D-2129-08 TCGA-CV-7433-10A-01D-2129-08 g.chr6:33284113G>T c.581C>A c.(580-582)tCc>tAc p.S194Y HNSC 6 33284361 33284361 + Silent SNP G G A TCGA-D6-6516-01A-11D-1870-08 TCGA-D6-6516-10A-01D-1870-08 g.chr6:33284361G>A c.333C>T c.(331-333)tcC>tcT p.S111S HNSC 6 33284458 33284458 + Missense_Mutation SNP G G A TCGA-CN-A6UY-01A-12D-A34J-08 TCGA-CN-A6UY-10B-01D-A34M-08 g.chr6:33284458G>A c.236C>T c.(235-237)tCc>tTc p.S79F KIPAN 6 33283498 33283498 + Nonsense_Mutation SNP G G T TCGA-2Z-A9JT-01A-11D-A42J-10 TCGA-2Z-A9JT-10A-01D-A42M-10 g.chr6:33283498G>T c.1196C>A c.(1195-1197)tCa>tAa p.S399* KIPAN 6 33284668 33284668 + Missense_Mutation SNP C C T TCGA-DZ-6132-01A-11D-1961-08 TCGA-DZ-6132-11A-01D-1961-08 g.chr6:33284668C>T c.26G>A c.(25-27)aGt>aAt p.S9N KIRP 6 33283498 33283498 + Nonsense_Mutation SNP G G T TCGA-2Z-A9JT-01A-11D-A42J-10 TCGA-2Z-A9JT-10A-01D-A42M-10 g.chr6:33283498G>T c.1196C>A c.(1195-1197)tCa>tAa p.S399* KIRP 6 33284668 33284668 + Missense_Mutation SNP C C T TCGA-DZ-6132-01A-11D-1961-08 TCGA-DZ-6132-11A-01D-1961-08 g.chr6:33284668C>T c.26G>A c.(25-27)aGt>aAt p.S9N LIHC 6 33283384 33283384 + Missense_Mutation SNP G G A TCGA-2Y-A9H1-01A-11D-A382-10 TCGA-2Y-A9H1-10A-01D-A385-10 g.chr6:33283384G>A c.1310C>T c.(1309-1311)tCc>tTc p.S437F LUAD 6 33282863 33282863 + Missense_Mutation SNP T T C TCGA-86-A456-01A-11D-A24D-08 TCGA-86-A456-10A-01D-A24F-08 g.chr6:33282863T>C c.1831A>G c.(1831-1833)Agc>Ggc p.S611G LUAD 6 33282996 33282996 + Silent SNP C C A TCGA-05-4397-01A-01D-1265-08 TCGA-05-4397-10A-01D-1265-08 g.chr6:33282996C>A c.1698G>T c.(1696-1698)cgG>cgT p.R566R LUAD 6 33283128 33283128 + Missense_Mutation SNP G G C TCGA-55-A4DF-01A-11D-A24D-08 TCGA-55-A4DF-10A-01D-A24F-08 g.chr6:33283128G>C c.1566C>G c.(1564-1566)ttC>ttG p.F522L LUAD 6 33283189 33283189 + Missense_Mutation SNP C C G TCGA-50-5049-01A-01D-1625-08 TCGA-50-5049-10A-01D-1625-08 g.chr6:33283189C>G c.1505G>C c.(1504-1506)cGg>cCg p.R502P LUAD 6 33283774 33283774 + Missense_Mutation SNP G G A TCGA-44-7667-01A-31D-2063-08 TCGA-44-7667-10A-01D-2063-08 g.chr6:33283774G>A c.920C>T c.(919-921)cCa>cTa p.P307L LUAD 6 33284169 33284169 + Silent SNP G G A TCGA-MP-A4T4-01A-11D-A25L-08 TCGA-MP-A4T4-10A-01D-A25L-08 g.chr6:33284169G>A c.525C>T c.(523-525)tcC>tcT p.S175S LUAD 6 33284436 33284436 + Silent SNP G G C TCGA-55-A4DF-01A-11D-A24D-08 TCGA-55-A4DF-10A-01D-A24F-08 g.chr6:33284436G>C c.258C>G c.(256-258)gtC>gtG p.V86V LUSC 6 33284035 33284035 + Missense_Mutation SNP G G T TCGA-46-3769-01A-01D-0983-08 TCGA-46-3769-10A-01D-0983-08 g.chr6:33284035G>T c.659C>A c.(658-660)tCc>tAc p.S220Y OV 6 33282987 33282987 + Silent SNP C C T TCGA-23-2641-01A-01D-1526-09 TCGA-23-2641-10A-01D-1526-09 g.chr6:33282987C>T c.1707G>A c.(1705-1707)ctG>ctA p.L569L OV 6 33284546 33284546 + Nonsense_Mutation SNP G G A TCGA-04-1343-01A-01W-0488-09 TCGA-04-1343-10A-01W-0489-09 g.chr6:33284546G>A c.148C>T c.(148-150)Cag>Tag p.Q50* PAAD 6 33283321 33283321 + Frame_Shift_Del DEL C C - TCGA-3A-A9IO-01A-11D-A38G-08 TCGA-3A-A9IO-10A-01D-A38J-08 g.chr6:33283321delC c.1373delG c.(1372-1374)ggcfs p.G458fs PAAD 6 33284326 33284326 + Missense_Mutation SNP T T C TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr6:33284326T>C c.368A>G c.(367-369)gAc>gGc p.D123G PAAD 6 33284660 33284660 + Missense_Mutation SNP C C A TCGA-IB-7651-01A-11D-2154-08 TCGA-IB-7651-10A-01D-2154-08 g.chr6:33284660C>A c.34G>T c.(34-36)Gca>Tca p.A12S PRAD 6 33283001 33283001 + Missense_Mutation SNP G G A TCGA-KK-A5A1-01A-11D-A29Q-08 TCGA-KK-A5A1-11A-12D-A29Q-08 g.chr6:33283001G>A c.1693C>T c.(1693-1695)Cgc>Tgc p.R565C PRAD 6 33284252 33284252 + Nonsense_Mutation SNP G G A TCGA-EJ-A65G-01A-21D-A29Q-08 TCGA-EJ-A65G-10A-01D-A29Q-08 g.chr6:33284252G>A c.442C>T c.(442-444)Cga>Tga p.R148* SARC 6 33283754 33283754 + Missense_Mutation SNP G G A TCGA-QC-A7B5-01A-11D-A33E-09 TCGA-QC-A7B5-11A-11D-A33H-09 g.chr6:33283754G>A c.940C>T c.(940-942)Ccc>Tcc p.P314S SARC 6 33284329 33284329 + Missense_Mutation SNP G G A TCGA-DX-A8BP-01A-11D-A37C-09 TCGA-DX-A8BP-10A-01D-A37F-09 g.chr6:33284329G>A c.365C>T c.(364-366)gCt>gTt p.A122V SKCM 6 33283159 33283159 + Missense_Mutation SNP G G A TCGA-EE-A3J4-06A-11D-A20D-08 TCGA-EE-A3J4-10A-01D-A20D-08 g.chr6:33283159G>A c.1535C>T c.(1534-1536)cCg>cTg p.P512L SKCM 6 33283250 33283250 + Missense_Mutation SNP C C T TCGA-EE-A182-06A-11D-A196-08 TCGA-EE-A182-10A-01D-A198-08 g.chr6:33283250C>T c.1444G>A c.(1444-1446)Ggg>Agg p.G482R SKCM 6 33283416 33283416 + Silent SNP G G A TCGA-D9-A6EC-06A-11D-A30X-08 TCGA-D9-A6EC-10A-01D-A30X-08 g.chr6:33283416G>A c.1278C>T c.(1276-1278)atC>atT p.I426I SKCM 6 33283441 33283441 + Missense_Mutation SNP G G A TCGA-EE-A29D-06A-11D-A197-08 TCGA-EE-A29D-10A-01D-A199-08 g.chr6:33283441G>A c.1253C>T c.(1252-1254)cCc>cTc p.P418L SKCM 6 33283465 33283465 + Missense_Mutation SNP G G C TCGA-EE-A2GJ-06A-11D-A196-08 TCGA-EE-A2GJ-10A-01D-A198-08 g.chr6:33283465G>C c.1229C>G c.(1228-1230)tCc>tGc p.S410C SKCM 6 33283498 33283498 + Missense_Mutation SNP G G A TCGA-EE-A3J7-06A-11D-A20D-08 TCGA-EE-A3J7-10A-01D-A20D-08 g.chr6:33283498G>A c.1196C>T c.(1195-1197)tCa>tTa p.S399L SKCM 6 33283663 33283663 + Missense_Mutation SNP G G A TCGA-ER-A42L-06A-11D-A24R-08 TCGA-ER-A42L-10A-01D-A24R-08 g.chr6:33283663G>A c.1031C>T c.(1030-1032)tCc>tTc p.S344F SKCM 6 33283839 33283839 + Silent SNP G G A TCGA-EE-A182-06A-11D-A196-08 TCGA-EE-A182-10A-01D-A198-08 g.chr6:33283839G>A c.855C>T c.(853-855)acC>acT p.T285T SKCM 6 33283840 33283840 + Missense_Mutation SNP G G A TCGA-EE-A182-06A-11D-A196-08 TCGA-EE-A182-10A-01D-A198-08 g.chr6:33283840G>A c.854C>T c.(853-855)aCc>aTc p.T285I SKCM 6 33284312 33284312 + Missense_Mutation SNP G G A TCGA-ER-A19C-06A-11D-A196-08 TCGA-ER-A19C-10A-01D-A198-08 g.chr6:33284312G>A c.382C>T c.(382-384)Ctt>Ttt p.L128F SKCM 6 33284313 33284313 + Silent SNP G G A TCGA-GF-A6C9-06A-11D-A30X-08 TCGA-GF-A6C9-10A-01D-A30X-08 g.chr6:33284313G>A c.381C>T c.(379-381)ttC>ttT p.F127F SKCM 6 33284382 33284382 + Silent SNP G G A TCGA-DA-A3F8-06A-11D-A20D-08 TCGA-DA-A3F8-10A-01D-A20D-08 g.chr6:33284382G>A c.312C>T c.(310-312)gcC>gcT p.A104A SKCM 6 33284485 33284485 + Missense_Mutation SNP G G A TCGA-ER-A19A-06A-21D-A197-08 TCGA-ER-A19A-10A-01D-A199-08 g.chr6:33284485G>A c.209C>T c.(208-210)gCt>gTt p.A70V SKCM 6 33284653 33284653 + Missense_Mutation SNP G G A TCGA-GF-A3OT-06A-23D-A23B-08 TCGA-GF-A3OT-10A-01D-A23B-08 g.chr6:33284653G>A c.41C>T c.(40-42)cCc>cTc p.P14L

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand PTC-14C COSM4161066 c.1846T>G p.S616A Substitution - Missense 6:33315071-33315071 - Pat_08_B COSM5870386 c.1172delG p.G391fs*64 Deletion - Frameshift 6:33315745-33315745 - CHC1708T COSM4952329 c.1453A>T p.I485F Substitution - Missense 6:33315464-33315464 - PD4266a COSM5784927 c.1541A>G p.D514G Substitution - Missense 6:33315376-33315376 - sysucc-880T COSM5463550 c.215G>A p.R72Q Substitution - Missense 6:33316702-33316702 - ESCC_62 COSM5633182 c.601C>G p.Q201E Substitution - Missense 6:33316316-33316316 - PR-02-1899 COSM248407 c.1498C>T p.R500W Substitution - Missense 6:33315419-33315419 - TCGA-GF-A6C9-06 COSM4901327 c.381C>T p.F127F Substitution - coding silent 6:33316536-33316536 - Pat_70_A COSM5870384 c.1440_1441delGG p.D481fs*3 Deletion - Frameshift 6:33315476-33315477 - TCGA-EE-A3J7-06 COSM3921524 c.1196C>T p.S399L Substitution - Missense 6:33315721-33315721 - MO_1012 COSM5571560 c.1550T>C p.V517A Substitution - Missense 6:33315367-33315367 - TCGA-AD-6889-01 COSM1443775 c.1049delG p.G350fs*9 Deletion - Frameshift 6:33315868-33315868 - TCGA-EM-A3FP-01 COSM3374250 c.836C>A p.A279D Substitution - Missense 6:33316081-33316081 - TCGA-BH-A0B6-01 COSM3830257 c.204C>T p.F68F Substitution - coding silent 6:33316713-33316713 - Pat_28_B COSM5870385 c.1267G>A p.G423S Substitution - Missense 6:33315650-33315650 - TCGA-BH-A0B6-01 COSM3830256 c.1248C>G p.L416L Substitution - coding silent 6:33315669-33315669 - PD4006a COSM5795069 c.1488C>G p.H496Q Substitution - Missense 6:33315429-33315429 - TCGA-04-1343-01 COSM79319 c.148C>T p.Q50* Substitution - Nonsense 6:33316769-33316769 - TCGA-D9-A6EC-06 COSM4405005 c.1278C>T p.I426I Substitution - coding silent 6:33315639-33315639 - 8012207 COSM1169076 c.1466_1467insCC p.C490fs*16 Insertion - Frameshift 6:33315450-33315451 - TCGA-AA-3713-01 COSM1443776 c.780G>T p.E260D Substitution - Missense 6:33316137-33316137 - S01728 COSM316640 c.1807delG p.A603fs*>32 Deletion - Frameshift 6:33315110-33315110 - TCGA-EE-A2GJ-06 COSM3625702 c.1229C>G p.S410C Substitution - Missense 6:33315688-33315688 - TCGA-BH-A0AV-01 COSM5214577 c.1749delG p.P584fs*>51 Deletion - Frameshift 6:33315168-33315168 - LIM1215 COSM4354629 c.628A>C p.S210R Substitution - Missense 6:33316289-33316289 - OV207 COSM252925 c.205C>T p.R69W Substitution - Missense 6:33316712-33316712 - HCC2998 COSM3349748 c.1559A>C p.K520T Substitution - Missense 6:33315358-33315358 - TCGA-AP-A0LM-01 COSM1078010 c.1577A>G p.H526R Substitution - Missense 6:33315340-33315340 - TCGA-P4-A5E7-01 COSM3994879 c.427T>C p.C143R Substitution - Missense 6:33316490-33316490 - DLD1 COSM4625773 c.1814C>T p.A605V Substitution - Missense 6:33315103-33315103 - TCGA-EK-A2RJ-01 COSM4831842 c.612C>T p.S204S Substitution - coding silent 6:33316305-33316305 - sysucc-1050T COSM3761994 c.928A>G p.T310A Substitution - Missense 6:33315989-33315989 - TCGA-DK-A1A3-01 COSM421365 c.264C>G p.L88L Substitution - coding silent 6:33316653-33316653 - TCGA-BT-A2LB-01 COSM3777567 c.620A>G p.N207S Substitution - Missense 6:33316297-33316297 - TCGA-EE-A2MI-06 COSM3625703 c.1217C>T p.S406F Substitution - Missense 6:33315700-33315700 - TCGA-A3-3374-01 COSM1496344 c.1188T>C p.L396L Substitution - coding silent 6:33315729-33315729 - T2932 COSM4742110 c.1728T>C p.P576P Substitution - coding silent 6:33315189-33315189 - RK119_C01 COSM3745191 c.1136A>G p.E379G Substitution - Missense 6:33315781-33315781 - CSCC-31-T COSM4558043 c.752G>A p.G251E Substitution - Missense 6:33316165-33316165 - TCGA-B5-A11Y-01 COSM400036 c.310G>A p.A104T Substitution - Missense 6:33316607-33316607 - TCGA-BR-6802-01 COSM3873163 c.1073T>C p.I358T Substitution - Missense 6:33315844-33315844 - PTC-46C COSM4161067 c.1185T>G p.G395G Substitution - coding silent 6:33315732-33315732 - HCC159T COSM5806653 c.63G>T p.P21P Substitution - coding silent 6:33316854-33316854 - CHC892T COSM4960282 c.1046G>A p.G349E Substitution - Missense 6:33315871-33315871 - TCGA-A5-A0G9-01 COSM1078013 c.1238C>A p.P413H Substitution - Missense 6:33315679-33315679 - 19 COSM5746563 c.866delC p.P289fs*12 Deletion - Frameshift 6:33316051-33316051 - PD13607a COSM5780132 c.380T>G p.F127C Substitution - Missense 6:33316537-33316537 - 8013222 COSM1158596 c.402C>A p.L134L Substitution - coding silent 6:33316515-33316515 - TCGA-AM-5820-01 COSM3349759 c.1100C>T p.P367L Substitution - Missense 6:33315817-33315817 - HCC098T COSM5806653 c.63G>T p.P21P Substitution - coding silent 6:33316854-33316854 - LUAD-S01478 COSM400036 c.310G>A p.A104T Substitution - Missense 6:33316607-33316607 - Patient5_Tu COSM1235708 c.1772A>G p.E591G Substitution - Missense 6:33315145-33315145 - TCGA-CU-A0YR-01 COSM421366 c.312C>T p.A104A Substitution - coding silent 6:33316605-33316605 - 169 COSM3729341 c.196C>T p.R66W Substitution - Missense 6:33316721-33316721 - TCGA-CK-5916-01 COSM1443777 c.566C>T p.A189V Substitution - Missense 6:33316351-33316351 - BN23T COSM1621517 c.1738A>G p.T580A Substitution - Missense 6:33315179-33315179 - sysucc-825T COSM5485296 c.567G>A p.A189A Substitution - coding silent 6:33316350-33316350 - TCGA-D1-A167-01 COSM1078011 c.1504C>T p.R502W Substitution - Missense 6:33315413-33315413 - SW403 COSM4655383 c.1569G>T p.K523N Substitution - Missense 6:33315348-33315348 - LUAD-CHTN-MAD06-00668 COSM360167 c.1740T>A p.T580T Substitution - coding silent 6:33315177-33315177 - DN13027 COSM5780132 c.380T>G p.F127C Substitution - Missense 6:33316537-33316537 - ESO-1059 COSM1270705 c.1083C>A p.V361V Substitution - coding silent 6:33315834-33315834 - MD-328 COSM303591 c.1672C>T p.R558C Substitution - Missense 6:33315245-33315245 - TCGA-FD-A3SR-01 COSM3777568 c.198G>A p.R66R Substitution - coding silent 6:33316719-33316719 - 3206A7_009_T COSM5043033 c.362C>A p.A121D Substitution - Missense 6:33316555-33316555 - ESCC-D10 COSM5045206 c.581C>T p.S194F Substitution - Missense 6:33316336-33316336 - RKO COSM4614969 c.820delG p.A274fs*27 Deletion - Frameshift 6:33316097-33316097 - PTC-7C COSM3761994 c.928A>G p.T310A Substitution - Missense 6:33315989-33315989 - TCGA-BR-A453-01 COSM303591 c.1672C>T p.R558C Substitution - Missense 6:33315245-33315245 - TCGA-DK-A1A3-01 COSM421367 c.1459C>T p.L487L Substitution - coding silent 6:33315458-33315458 - CHC892T COSM4960282 c.1046G>A p.G349E Substitution - Missense 6:33315871-33315871 - S01728 COSM316640 c.1807delG p.A603fs*>32 Deletion - Frameshift 6:33315110-33315110 - TCGA-G4-6320-01 COSM3697789 c.568C>T p.R190C Substitution - Missense 6:33316349-33316349 - TCGA-HU-A4G8-01 COSM3873164 c.897C>T p.Y299Y Substitution - coding silent 6:33316020-33316020 - ESO-2143 COSM1270706 c.1240C>T p.R414* Substitution - Nonsense 6:33315677-33315677 - MO_1012 COSM1443777 c.566C>T p.A189V Substitution - Missense 6:33316351-33316351 - ICGC_0002 COSM1158596 c.402C>A p.L134L Substitution - coding silent 6:33316515-33316515 - Pat_16_B COSM5870383 c.1679G>A p.R560Q Substitution - Missense 6:33315238-33315238 - LUAD_E01047 COSM390281 c.911G>T p.G304V Substitution - Missense 6:33316006-33316006 - LUAD-NYU947 COSM377074 c.1820C>T p.T607M Substitution - Missense 6:33315097-33315097 - C089 COSM5543624 c.1252C>T p.P418S Substitution - Missense 6:33315665-33315665 - T3262 COSM4742112 c.197G>A p.R66Q Substitution - Missense 6:33316720-33316720 - TCGA-FK-A3SD-01 COSM3374248 c.1099C>T p.P367S Substitution - Missense 6:33315818-33315818 - pfg008T COSM1643028 c.1400C>T p.P467L Substitution - Missense 6:33315517-33315517 - TCGA-E2-A1IN-01 COSM1487660 c.1068C>T p.L356L Substitution - coding silent 6:33315849-33315849 - TCGA-EI-6882-01 COSM3430543 c.224T>C p.L75P Substitution - Missense 6:33316693-33316693 - CSCC-16-T COSM4532257 c.1869G>A p.V623V Substitution - coding silent 6:33315048-33315048 - TCGA-FU-A3YQ-01 COSM4823488 c.777G>A p.L259L Substitution - coding silent 6:33316140-33316140 - CSCC-16-T COSM4527557 c.1473G>A p.G491G Substitution - coding silent 6:33315444-33315444 - TCGA-AM-5820-01 COSM5134604 c.1025delG p.G342fs*17 Deletion - Frameshift 6:33315892-33315892 - TCGA-AP-A0LJ-01 COSM1078012 c.1377G>A p.T459T Substitution - coding silent 6:33315540-33315540 - TCGA-46-3769-01 COSM742337 c.659C>A p.S220Y Substitution - Missense 6:33316258-33316258 - TCGA-EL-A3H5-01 COSM3374247 c.1710C>T p.G570G Substitution - coding silent 6:33315207-33315207 - TCGA-EE-A29D-06 COSM3625701 c.1253C>T p.P418L Substitution - Missense 6:33315664-33315664 - TCGA-GF-A3OT-06 COSM3625705 c.41C>T p.P14L Substitution - Missense 6:33316876-33316876 - TCGA-AA-3492-01 COSM1443778 c.526G>A p.G176R Substitution - Missense 6:33316391-33316391 - TCGA-ER-A19C-06 COSM3921525 c.382C>T p.L128F Substitution - Missense 6:33316535-33316535 - TCGA-EE-A182-06 COSM3625700 c.1444G>A p.G482R Substitution - Missense 6:33315473-33315473 - TCGA-DA-A3F8-06 COSM421366 c.312C>T p.A104A Substitution - coding silent 6:33316605-33316605 - LUAD-S01357 COSM387644 c.1281G>C p.L427L Substitution - coding silent 6:33315636-33315636 - LC_S11 COSM1187008 c.715G>T p.G239C Substitution - Missense 6:33316202-33316202 - T3080 COSM1443775 c.1049delG p.G350fs*9 Deletion - Frameshift 6:33315868-33315868 - TCGA-AP-A0LE-01 COSM1078012 c.1377G>A p.T459T Substitution - coding silent 6:33315540-33315540 - TCGA-DZ-6132-01 COSM3994880 c.26G>A p.S9N Substitution - Missense 6:33316891-33316891 - T3182 COSM4742111 c.1373delG p.G458fs*47 Deletion - Frameshift 6:33315544-33315544 - TCGA-AX-A0J1-01 COSM1078014 c.347G>A p.R116H Substitution - Missense 6:33316570-33316570 - TCGA-BH-A0E1-01 COSM451303 c.667G>A p.E223K Substitution - Missense 6:33316250-33316250 - HCC138T COSM3349742 c.1747G>T p.G583W Substitution - Missense 6:33315170-33315170 - PDA_102 COSM5003604 c.584G>T p.S195I Substitution - Missense 6:33316333-33316333 - TCGA-EM-A2OV-01 COSM3374249 c.1085G>A p.R362H Substitution - Missense 6:33315832-33315832 - CSCC-54-T COSM4504229 c.659C>T p.S220F Substitution - Missense 6:33316258-33316258 - TCGA-FD-A3SS-01 COSM3777566 c.627C>T p.F209F Substitution - coding silent 6:33316290-33316290 - TCGA-EJ-A65G-01 COSM4879423 c.442C>T p.R148* Substitution - Nonsense 6:33316475-33316475 - CHC1708T COSM4952329 c.1453A>T p.I485F Substitution - Missense 6:33315464-33315464 - TCGA-23-2641-01 COSM1329757 c.1707G>A p.L569L Substitution - coding silent 6:33315210-33315210 - CSCC-20-T COSM4510173 c.829C>A p.P277T Substitution - Missense 6:33316088-33316088 - TCGA-EE-A3J4-06 COSM3921523 c.1535C>T p.P512L Substitution - Missense 6:33315382-33315382 - TCGA-A2-A0EU-01 COSM5194684 c.31delG p.A11fs*29 Deletion - Frameshift 6:33316886-33316886 - TCGA-AA-3492-01 COSM3697790 c.268G>T p.G90C Substitution - Missense 6:33316649-33316649 - TCGA-ER-A19A-06 COSM3625704 c.209C>T p.A70V Substitution - Missense 6:33316708-33316708 - TCGA-B2-4101-01 COSM3366466 c.1160A>T p.Y387F Substitution - Missense 6:33315757-33315757 - TCGA-GD-A2C5-01 COSM1312081 c.1125C>T p.V375V Substitution - coding silent 6:33315792-33315792 - TCGA-AM-5821-01 COSM3761994 c.928A>G p.T310A Substitution - Missense 6:33315989-33315989 - TCGA-KK-A5A1-01 COSM4392008 c.1693C>T p.R565C Substitution - Missense 6:33315224-33315224 - TCGA-F4-6856-01 COSM1443774 c.1227delC p.S410fs*45 Deletion - Frameshift 6:33315690-33315690 - PD4127a COSM165653 c.1301C>T p.S434L Substitution - Missense 6:33315616-33315616 - CSCC-27-T COSM4513342 c.934C>T p.L312L Substitution - coding silent 6:33315983-33315983 -

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.205952;Hs.206112;Hs.206770 6p21.3 611439 2419328|CGAP|BC018541|C/T|non-coding||2489|Validated

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer AAGGG - Frameshift p.P418Gfs*50 c.1252_1256delCCCTT 6 33283438 HNSC A G Missense p.I358T c.1073T>C 6 33283621 STAD CA - Frameshift p.C563*fs*1 c.1689_1690delTG 6 33283004 HNSC C A Synonymous p.L312L c.936G>T 6 33283758 HNSC C A Synonymous p.R566R c.1698G>T 6 33282996 LUAD C - Frameshift p.A603Rfs*86 c.1807delG 6 33282887 SCLC C G Missense p.R502P c.1505G>C 6 33283189 LUAD C T Missense p.A104T c.310G>A 6 33284384 UCEC C T Missense p.E223K c.667G>A 6 33284027 BRCA C T Missense p.E2K c.4G>A 6 33284690 CM C T Missense p.G482R c.1444G>A 6 33283250 CM C T Missense p.R116H c.347G>A 6 33284347 BRCA C T Missense p.R362H c.1085G>A 6 33283609 THCA C T Synonymous p.T459T c.1377G>A 6 33283317 UCEC G A Missense p.A274V c.821C>T 6 33283873 HNSC G A Missense p.A70V c.209C>T 6 33284485 CM G A Missense p.L128F c.382C>T 6 33284312 CM G A Missense p.P14S c.40C>T 6 33284654 CM G A Missense p.P277S c.829C>T 6 33283865 CM G A Missense p.P367S c.1099C>T 6 33283595 THCA G A Missense p.P467L c.1400C>T 6 33283294 STAD G A Missense p.P512L c.1535C>T 6 33283159 CM G A Missense p.R500W c.1498C>T 6 33283196 THCA G A Missense p.R565C c.1693C>T 6 33283001 PRAD G A Missense p.S218L c.653C>T 6 33284041 HNSC G A Missense p.S399L c.1196C>T 6 33283498 CM G A Missense p.S406F c.1217C>T 6 33283477 CM G A Missense p.S406F c.1217C>T 6 33283477 HNSC G A Missense p.S434L c.1301C>T 6 33283393 BRCA G A Nonsense p.Q50* c.148C>T 6 33284546 OV G A Nonsense p.R148* c.442C>T 6 33284252 PRAD G A Nonsense p.R414* c.1240C>T 6 33283454 ESCA G A Synonymous p.A104A c.312C>T 6 33284382 BLCA G A Synonymous p.A104A c.312C>T 6 33284382 CM G A Synonymous p.G570G c.1710C>T 6 33282984 THCA G A Synonymous p.L356L c.1068C>T 6 33283626 BRCA G A Synonymous p.L487L c.1459C>T 6 33283235 BLCA G A Synonymous p.L6L c.16C>T 6 33284678 CM G A Synonymous p.V375V c.1125C>T 6 33283569 BLCA G C Missense p.L328V c.982C>G 6 33283712 HNSC G C Missense p.S410C c.1229C>G 6 33283465 CM G C Synonymous p.L88L c.264C>G 6 33284430 BLCA GG AA Missense p.T285I c.854_855delinsTT 6 33283839 CM G T Missense p.A279D c.836C>A 6 33283858 THCA G T Missense p.S220Y c.659C>A 6 33284035 LUSC G T Synonymous p.L134L c.402C>A 6 33284292 PAAD G T Synonymous p.V361V c.1083C>A 6 33283611 ESCA T A Missense p.Y387F c.1160A>T 6 33283534 RCCC T C Missense p.N207S c.620A>G 6 33284074 BLCA