PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus HDAC1 KCTD11 20081843 biogrid exp GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP P G KCTD11 KCTD11 21237243 biogrid exp GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP P G CUL3 KCTD11 21237243,25974686,20081843 biogrid exp GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP P G KCTD11 KCNH3 16082366 pred GP GP G P GP G GP G GP G P GP P GP GP GP G P P P GP GP P P KCNJ13 KCTD11 16082366 pred P P P P P P P P P P GP P P P P P P P P P P P KCTD11 CAND1 25402006 pred G GP G G G G GP G GP GP G G G GP G GP G G G G GP P GP G G P G KLHL12 KCTD11 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G KCNJ6 KCTD11 16082366 pred P P G P GP P P G P P P P P GP P GP G P P P P P P P P KCTD11 KCND2 16082366 pred P P G P GP P G P P P P GP GP P G P P P P KCTD11 KCNG1 16082366 pred P P G P P P P P P P P P P P GP P P P P P P P G KCTD16 KCTD11 16082366 pred G GP G P G P P GP P GP P P P P CACNB4 KCTD11 16082366 pred P P G P GP G P P G P P P P P GP P P GP GP P P P P P KCTD11 KCNK17 16082366 pred G G G G G GP G G G G G G G GP G G G G G G G GP G GP P G KCTD11 KCTD6 16082366 pred G GP G P GP G GP GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP P G KCTD11 KCNH6 16082366 pred P P GP G GP GP G GP P P G P GP G GP G P GP GP P GP P P P KCTD11 KCNJ15 16082366 pred GP P P P P P GP P GP P GP P P GP GP GP GP P GP GP GP P KCTD11 KCNH4 16082366 pred G G G G G G G TNFAIP1 KCTD11 16082366 pred G G G G G G GP G GP G G G G GP G G GP G G G GP GP G GP G KCTD11 KCNN2 16082366 pred P GP G P GP G GP P G P GP P GP P GP GP G P GP P P P P P P KCTD11 KCNJ9 16082366 pred G G G G G G G GRIK1 KCTD11 16082366 pred P GP G P GP G P P G P P GP P GP GP P P P P P P P P P CNGA3 KCTD11 16082366 pred G KCNJ3 KCTD11 16082366 pred G G P GP G G P G GP G P GP GP G G G G P GP P G KCNA3 KCTD11 16082366 pred P G G P G GP KCNA10 KCTD11 16082366 pred P P P P P P P P P P P P P P P P P P P P P P DNTT KCTD11 25402006 pred GP G G G G G G GP P GP G G G G P G P P G GP KCTD11 KCNV1 16082366 pred G G G KCTD11 KCNG4 16082366 pred G GP GP G G G G GP G G P P G KCTD11 KCTD14 16082366 pred P P P P P P P P P P P P KCNT1 KCTD11 16082366 pred G P G P G P P P GRIA4 KCTD11 16082366 pred G G G G G G G G G KCTD11 KCNJ16 16082366 pred P P G GP G P P G GP P G P GP GP G GP GP P GP P GP P KCTD11 KCNK6 16082366 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP G GP P GP GP GP P G KCTD11 KCNS1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G KCNA5 KCTD11 16082366 pred P P P GP P G P P P P P P P P P P P P P P KCTD11 ABTB2 25402006 pred GP GP G P GP G GP G G GP G GP G G GP GP G GP G GP GP GP P GP P GP P G KCTD11 KCNH5 16082366 pred P P GP P P G P P GP G G P P P P CACNB3 KCTD11 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G KCTD11 KCNK16 16082366 pred P P P P GP GP G GP G P P GP P P GP G GP P P P GP G GP P G KCTD11 HCN2 16082366 pred G G G G G G KCTD11 CNGA4 16082366 pred G G G KCNJ2 KCTD11 16082366 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP P G KCNC1 KCTD11 16082366 pred G G GP G G G GP G G G G G KCTD11 KCNV2 16082366 pred P P P P P P P P P P P P P KCTD11 KCNK4 16082366 pred KCNK2 KCTD11 16082366 pred G P P P P P KCTD11 KCNK7 16082366 pred G KCNMA1 KCTD11 16082366 pred GP GP G P GP G G GP G GP GP GP G G GP GP GP G G GP GP GP GP GP G P G KCTD11 KCNK15 16082366 pred P P P P P P P P P KCNQ4 KCTD11 16082366 pred P G GP G GP GP G P P P P G GP GP G GP P G P G P G GRIA2 KCTD11 16082366 pred G GP G G GP G KCNA2 KCTD11 16082366 pred G G GP G G P G P P P P G GP GP P P G P P P P GP P KCNC4 KCTD11 16082366 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP P GP P GP GP GP P G KCNH1 KCTD11 16082366 pred P P P P P P P P P P P KCNK10 KCTD11 16082366 pred P G GP G GP GP G GP G GP GP GP GP G GP G GP P GP GP GP P G KCTD11 KCNF1 16082366 pred P P G P GP P P G P P P P P GP P GP P P P P GP P P P KCNC3 KCTD11 16082366 pred P G P GP G P G G GP GP G G P GP GP GP G P G P P P P P G KCNK1 KCTD11 16082366 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP P G KCNN4 KCTD11 16082366 pred GP G G P G G G G G G G G G G G P G G G G KCTD11 SHKBP1 16082366 pred GP GP P P G P GP G GP P GP GP G GP P GP GP G GP GP G GP GP GP P G KCNQ2 KCTD11 16082366 pred G G GP G G G GP G G P KCTD11 KCTD12 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G KCTD11 KCNN3 16082366 pred P P G GP P GP G P P P P GP P P P P P G GP P CNGA1 KCTD11 16082366 pred G G G G G G G G G G G G G G G G G G G KCTD11 CNGB3 16082366 pred G G G G G G G G G G G G G G G G G GRIA1 KCTD11 16082366 pred G P GP G P G P GP G P KCNA1 KCTD11 16082366 pred GP GP G P GP G GP GP G P GP P P G GP GP GP GP G GP P GP P GP P GP P G KCNJ5 KCTD11 16082366 pred P GP G GP G GP GP G GP GP P G G GP GP GP GP G GP P GP GP G GP P G KCTD11 KCNJ14 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G CNGA2 KCTD11 16082366 pred P P P P P P P P P P P P KCTD11 KCTD18 16082366 pred GP GP G GP G G GP G GP GP GP G G GP GP G GP G GP GP GP GP G GP P G KCNJ10 KCTD11 16082366 pred P P G GP G P P G GP P P GP P GP P P P P P P P P P P G KCTD11 KCNK9 16082366 pred G G G KCTD11 KCTD17 16082366 pred P G P GP G P P G P P P P GP P P G P P P P P CACNB1 KCTD11 16082366 pred P G G GP G G P G GP G G GP GP GP G GP G GP GP G P GP P P G KCNA6 KCTD11 16082366 pred P P G P GP G P P G P GP P P GP GP GP GP P P GP P P P GP P KCTD11 KCNH8 16082366 pred P G P GP G GP G P P GP P GP G G P GP GP P KCNJ8 KCTD11 16082366 pred GP GP P G G GP GP GP GP G G GP G GP G P GP P P GP G GP G KCTD11 kcnj12x 16082366 pred KCNH2 KCTD11 16082366 pred GP GP G P G G GP GP G GP GP GP GP G GP G G GP G GP GP GP P GP GP GP P G KCTD11 KCNG3 16082366 pred G G KCNJ4 KCTD11 16082366 pred P G P GP G P G P P P P P GP P G P P P P P P KCNA4 KCTD11 16082366 pred GP G P P G P P P P P P P P P P P P P P P P P KCNJ1 KCTD11 16082366 pred P P P P GP P P P P P P P KCTD11 KCNN1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G KCTD11 KCTD15 16082366 pred G G G G G GP G G G G G G G G G G G G G G G P G G G G KCTD11 KCNS2 16082366 pred GP P G P GP P GP G GP P P P P GP GP G P P P P GP P P G KCTD11 KCNQ5 16082366 pred P P G P GP G P P G P P P P GP P P G P P P KCNK3 KCTD11 16082366 pred G G G G G G G G G G G G G G G G G G G P G G G GRIK4 KCTD11 16082366 pred KCNQ1 KCTD11 16082366 pred P GP P GP GP GP P GP G G GP P GP G GP P GP G GP P KCTD11 KCNG2 16082366 pred P P P P P P P P P P P P P P P P P P P P HCN1 KCTD11 16082366 pred G GP G P G P P P P GP P P P P P KCNK5 KCTD11 16082366 pred G GP P GP G GP G GP G G GP G G GP G G G G G G G G GP G KCTD11 KCTD13 16082366 pred GP GP G GP G GP GP G GP GP GP G G GP GP GP GP G GP GP GP P GP G GP P G KCNB1 KCTD11 16082366 pred G G G GP G GP G G G G GP G G GP GP G G G GP GP G P GP G G G KCTD11 KCNS3 16082366 pred GP P G P GP G GP GP G GP GP GP P G GP GP P GP G GP GP GP P GP P GP P G KCTD11 KCNA7 16082366 pred KCNQ3 KCTD11 16082366 pred GP GP G P GP G GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP P G KCTD11 KCTD5 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G GRIA3 KCTD11 16082366 pred P GP G P GP P P G P P P P GP P P P P P P P P P P KCTD11 KCNB2 16082366 pred G G G G G G G G G G G G G G G G G KCTD11 KCNK12 16082366 pred G G G G G G KCNJ11 KCTD11 16082366 pred P P P P P P P G P P P CACNB2 KCTD11 16082366 pred GP G GP GP GP G GP GP P P G G GP GP GP G P G GP G P GP P G KCTD11 KCTD10 16082366 pred G GP G P GP G GP GP G GP G GP GP G GP GP GP GP G GP GP GP P GP GP GP P G KCTD11 KCTD7 16082366 pred P P P P P P P P P P P P P P KCTD11 KCNK13 16082366 pred P P P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q693B1 Q13547 enzymatic study 20081843 direct interaction X 2 Q693B1 Q13547 affinity chromatography technology 20081843 physical association X 2 Q693B1 A0A024R475 affinity chromatography technology 20081843 physical association X 2 Q693B1 A0A024R475 affinity chromatography technology 21237243 physical association X 2 Q693B1 Q693B1 affinity chromatography technology 21237243 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q693B1 Q13547 KCTD11 HDAC1 0.21 20081843 Q693B1 Q13618 KCTD11 CUL3 0.569 25974686,20081843,21237243 Q693B1 Q693B1 KCTD11 KCTD11 0.659 27152988,21237243