PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus AP1G2 ATXN1L 16713569 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 EGFR 23956138 biogrid exp GP GP G GP G GP G GP GP G G G GP GP G G G GP GP G P GP G GP GP G AP1G2 IST1 26344197 biogrid exp GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 UBE2Z 19549727 intact exp GP GP G G GP GP G GP G GP GP GP GP G GP GP G GP G GP GP GP P GP GP GP GP G AP1G2 AAGAB 26186194 biogrid exp GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 SYNE4 26186194 biogrid exp P GP P GP GP GP G GP GP GP P G GP GP P GP G GP GP GP P GP P GP P G AP1G2 AFTPH 14665628 hprd exp GP GP G G GP GP GP GP G GP G GP GP G GP GP G GP G GP GP GP P GP G GP GP G AP1G2 LRRK2 24725412 intact exp G G G G G GP GP G G GP GP GP G G G GP G GP G G G P G G GP P G AP1G2 CENPK 25416956 biogrid,intact exp G G G G G G G G AP1G2 XRN1 15231747 hprd,biogrid,i2d,intact exp GP GP G G GP GP GP GP G GP GP GP G G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 PRMT6 23455924 biogrid,intact exp GP GP G G GP GP G GP G GP G GP G G GP GP GP GP G GP GP GP GP G GP GP G KDM1A AP1G2 23455924 biogrid,intact exp GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP G GP P GP GP GP GP G XPO1 AP1G2 26673895 biogrid exp, ortho GP GP G G GP GP GP GP G GP G GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 AP1G2 16713569 mint exp, ortho GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 AP1S2 26496610,9733768, 25402006, 21836163, 16082366 hprd,biogrid,intact exp, ortho, pred G GP G G G GP GP GP G GP GP G G G GP GP G GP G GP G G P GP G GP GP G AP1G2 AP2M1 26186194, 25402006, 23023127 biogrid exp, pred GP GP G G G GP GP GP G GP GP GP GP G GP GP G GP G GP G G GP G GP GP G AP1G2 SYNRG 10477754,10814529, 25402006, 16082366 hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 NEDD4 18772139, 25402006 biogrid exp, pred GP GP G GP P GP GP GP G GP GP G GP GP GP GP G GP GP GP P GP GP GP P G AP1G2 AP1M2 26186194, 25402006, 23023127, 21836163 biogrid exp, pred G G G G G G G G G G G G G G G G G AP1G2 RABEP1 12505986,14665628, 25402006, 21836163 hprd,biogrid,intact,bci exp, pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 AP1S1 9733768, 25402006, 21836163, 16082366 hprd,biogrid exp, pred GP GP G G GP GP G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 UBE2G2 ortho GP GP G G GP GP G GP G GP GP GP GP G GP GP G GP G GP GP G GP GP GP GP G AP1G2 DUSP12 ortho GP G G G GP GP G GP G GP GP GP G G GP GP G GP G GP GP GP P GP G GP G G AP1G2 HSPA4 ortho GP GP G G GP GP G GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 GMPPB ortho P P P P P P P P P P P P P P P P P P P P P AP1G2 MAD2L1 ortho P G G P P GP P P P GP G GP P G P P GP P GP GP GP GP AP1G2 ATP6V1B2 ortho G GP G G GP GP G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP G AP1G2 TUBA1C ortho GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 NHP2L1 ortho GP GP G G G GP GP GP G GP GP G G G GP GP G GP G GP GP GP GP G GP GP G AP1G2 UBE2V2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 GPI ortho GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 DNAJB1 ortho GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 DDX55 ortho GP GP G G GP GP GP GP G GP G GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 UPF2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G DKC1 AP1G2 ortho P P P P P P P P P P P P P P P P P P P P P P AP1G2 PRKACB ortho GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 NOP58 ortho GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 H3F3C ortho P P P P P P P P P P P P P P P P P P P P P P AP1G2 WDR76 ortho G GP GP P GP G P GP GP G G GP G G P G GP G AP1G2 CCT2 ortho GP GP G G GP GP GP GP G G GP GP GP G GP GP G GP G GP GP G GP GP GP GP G AP1G2 ATP8A2 ortho G G GP GP G P P P P GP P G P P P P GP NOP56 AP1G2 ortho P P P P P AP1G2 TUBB4B ortho GP G G G G GP G GP G G G G GP G GP GP G GP G GP GP GP GP GP GP GP G AP1G2 PKM ortho GP GP G G GP GP G GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP G AP1G2 VAC14 21836163 ortho, pred GP G GP P P G GP GP GP GP G GP GP GP P G P GP GP GP G GP GP AP1G2 AP1M1 25402006 ortho, pred GP GP G G GP GP GP GP G GP GP GP G G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 CLTC 21836163 ortho, pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP G AP1G2 GULP1 16082366 pred GP GP G P GP GP GP G GP P G G G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 STAMBPL1 21836163 pred G GP G G GP GP GP GP G GP G GP GP G GP GP G GP G P GP GP P GP GP GP GP AP1G2 ANKRD27 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 PRKCQ 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G COPE AP1G2 21836163 pred GP GP G G GP GP G GP G GP GP GP G G GP GP G GP G GP GP GP GP GP GP GP G AP1G2 GGA1 25402006, 23023127 pred GP GP G G GP GP GP GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 SSRP1 21836163 pred G GP G G G GP G GP G G G GP GP G G GP GP GP G GP G G G G GP GP G AP1G2 AP2A2 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 SCNN1A 25402006 pred GP GP P P P GP GP P GP GP G GP P P GP G P GP GP P GP P GP GP G AP1G2 GCC1 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 ITCH 25402006, 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 ARCN1 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 AP1B1 25402006, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 AP2S1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 AP2A1 23023127 pred GP GP G G GP GP G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G1 AP1G2 25402006, 23023127, 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 AP4B1 25402006 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 AP3M1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 PMEPA1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G AP1G2 COPZ1 23023127 pred GP GP G G G GP GP GP G GP G GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 GGA3 25402006, 23023127, 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP G GP P GP GP GP GP G AP1G2 CHID1 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP G AP1G2 AP3S1 23023127 pred GP G G G G GP GP G G GP G GP G G G GP G G G G G GP G G G GP G AP1G2 DCTN4 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G SCAMP3 AP1G2 25402006 pred G G G G G GP GP G G GP G GP GP G G GP G GP G G G G P G G GP GP G AP1G2 ARHGAP22 21836163 pred P P G GP P P G P P G GP P P P P P P P P P AP1G2 RABGEF1 25402006 pred P P P P P GP G GP P P P GP P P GP G P P GP P P GP P P AP1G2 RABGEF1 25402006 pred P P P P P GP G GP P P P GP P P GP G P P GP P P GP P P AP1G2 ITSN1 16082366 pred G GP G G G GP GP GP G GP GP GP GP G GP GP G G G GP G GP P GP G GP GP G AP1G2 PRKCI 23023127 pred GP GP G G G GP G GP G GP G GP G G GP GP G GP G GP GP G GP G GP GP G AP1G2 PACSIN1 23023127 pred G GP G P G P GP G SCAMP1 AP1G2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 CHMP5 21836163 pred G GP G G G GP GP GP G GP G G G G GP GP G GP G GP GP G GP G GP GP G MYO1G AP1G2 21836163 pred G GP G G GP GP G GP G GP G GP GP G G GP G G G GP G G G GP GP GP G AP1G2 WWP1 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 WDFY1 21836163 pred GP GP G G G GP GP GP G GP GP GP GP G GP GP G GP G GP GP GP P GP GP GP GP G AP1G2 AP4S1 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 AMOTL1 25402006 pred G G G G G GP GP GP G G G G G G G GP G G G GP G G G G G GP G AP1G2 TTYH3 25402006 pred G GP G G G GP GP GP G GP GP G G G GP GP GP G G G GP GP GP G G GP G AP1G2 SLC24A5 21836163 pred CLTCL1 AP1G2 21836163 pred AP1G2 EHD1 21836163 pred G G G G G GP GP GP G GP G GP GP G G GP GP G G GP G G G GP G GP G AP1G2 GGA2 25402006, 23023127, 21836163 pred GP GP G G G GP G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 M6PR 16082366 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 EHD3 21836163 pred G G G G G GP GP GP G GP G GP GP G G GP GP G GP G G GP G P G AP1G2 AP1S3 25402006, 23023127 pred G TGOLN2 AP1G2 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 G3BP2 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 SRGAP1 21836163 pred G GP G GP G GP G GP GP G G G GP GP G GP G G G GP G G GP G AP1G2 PRKCSH 16082366 pred GP GP G G GP GP G GP G GP GP GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 RIMS1 23023127 pred P P G G G GP GP G P P P GP GP P G P GP GP P GP GP GP G AP1G2 ISG15 25402006 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 NDFIP1 25402006 pred GP GP G G GP GP G GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 RANBP2 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 RAB11FIP2 23023127 pred GP GP G G G GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 ITSN2 16082366 pred G G G G G GP G GP G GP GP G G G GP GP G GP G GP GP G GP G GP GP G AP1G2 WBP2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 AP3M2 23023127 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 IGF2R 16082366 pred GP GP G G G GP GP GP G GP GP GP GP G GP GP G GP G GP GP GP GP GP GP GP G AP1G2 GCC2 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 NECAP2 25402006 pred G GP G G GP GP G GP G GP G GP GP G GP GP GP G G GP G G GP G GP GP G AP1G2 ARFIP1 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 NECAP1 25402006 pred G GP G G G G G GP G GP GP GP G G GP G G G G GP G GP P GP G G GP G AP1G2 KIF1A 23023127 pred P G G P GP GP P G P P P GP GP GP G GP G P GP P P GP P GP P G AP1G2 AP2B1 25402006, 21836163 pred G GP G G GP GP G GP G GP G GP GP G GP GP GP GP G GP GP GP GP GP GP GP G AP1G2 DNAJC5B 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 SNX4 21836163 pred G GP G G GP GP G GP G GP GP GP G G GP GP G GP G GP G G GP GP GP GP G AP1G2 LAPTM5 25402006 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP G GP G G GP GP GP GP GP GP G AP1G2 RUFY1 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP G GP G GP GP GP P GP GP GP GP G AP1G2 SCAMP5 21836163 pred G GP G G G GP GP GP G GP G GP G G G GP G GP G G GP G P G G GP GP G AP1G2 B4GALT6 21836163 pred GP GP G G GP GP GP GP G GP P P G G GP GP G P G P GP GP GP G GP GP AP1G2 EHD4 21836163 pred G G G G G GP GP GP G GP G GP GP G G GP GP G G GP G G G GP G GP G AP1G2 SNX30 23023127 pred GP GP G G GP GP P GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G HGS AP1G2 25402006 pred GP GP G G GP GP GP GP G GP G GP G G GP GP GP GP G GP GP GP P GP G GP GP G AP1G2 SLC9A7 21836163 pred P P P P P P P P P P P P P P P P P AP1G2 EHBP1 21836163 pred GP GP G G GP GP GP GP G GP GP GP GP G GP GP GP GP G GP GP GP P GP GP GP GP G AP1G2 NDFIP2 25402006 pred GP G G G GP GP G GP G GP G GP GP G GP GP G GP G G G GP P GP GP GP GP G AP1G2 SCNN1G 25402006 pred G G G G G AP1G2 COPZ2 23023127 pred GP GP G GP GP GP GP GP GP G G GP G GP GP G GP GP GP GP GP GP G AP1G2 RIN2 21836163 pred GP GP G G GP GP GP GP G GP GP GP G G GP GP G GP G GP GP GP P GP GP GP P G AP1G2 WDFY2 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 RC3H2 21836163 pred GP G G G G GP GP GP G GP GP G G G GP GP G GP G G G GP GP G GP GP G AP1G2 RAB4A 25402006, 21836163 pred P P P P P P P P P P P P P P P P P P P P P P AP1G2 TTYH2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G AP1G2 UNC13A 23023127 pred P P G P GP P G P P GP P G P P P P P P AP1G2 NEDD4L 23023127 pred GP GP G GP GP GP G GP G GP P G GP GP GP GP G GP GP G GP G GP G AP1G2 RAB3B 23023127 pred P G G GP G GP G GP G GP GP GP P AP1G2 HMHA1 21836163 pred G G G GP P G P G G GP G G P GP G GP G AP1G2 MLANA 25402006 pred G G AP4M1 AP1G2 25402006 pred G G G G G G G G AP1G2 SEC31B 21836163 pred P GP G GP GP G GP G GP GP P GP GP GP P P G P P P P G GP GP AP1G2 PDCD6IP 25402006, 23023127 pred G GP G G GP GP GP GP G GP GP GP G G GP GP GP GP G GP GP GP P GP G GP GP G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O75843 - 15231747 - X 2 O75843 - 11333915 - X 2 A0A024QYT6 O75843 two hybrid 9733768 direct interaction X 2 A0A024R2K1 O75843 two hybrid 14665628 direct interaction X 2 O75843 two hybrid 15231747 direct interaction X 2 O75843 O60341 two hybrid 23455924 direct interaction X 2 O75843 A0A024R3Z2 affinity chromatography technology 24654937 physical association X 2 P00533 O75843 affinity chromatography technology 23956138 physical association X 2 P46934-4 O75843 affinity chromatography technology 18772139 physical association X 2 P46934-4 O75843 affinity chromatography technology 18772139 physical association X 2 P46934-4 O75843 enzymatic study 18772139 direct interaction X 2 Q96LA8 O75843 two hybrid 23455924 direct interaction X 2 Q9BS16 O75843 two hybrid 25416956 direct interaction X 2 P0CG48 O75843 affinity chromatography technology 22505724 physical association X 2 P0CG48 O75843 affinity chromatography technology 23000965 physical association X 2 P0CG48 O75843 affinity chromatography technology 21139048 physical association X 2 P0CG48 O75843 affinity chromatography technology 21890473 physical association X 2 P0CG48 O75843 affinity chromatography technology 21906983 physical association X 2 P56377 O75843 two hybrid 9733768 direct interaction X 2 O75843 two hybrid 10814529 direct interaction X 2 P0C7T5 O75843 two hybrid 16713569 direct interaction X 2 O75843 two hybrid 15775984 association C 9 O75843 coimmunoprecipitation 15775984 association C 9 O75843 two hybrid 9733768 association C 8 P61966-2 O75843 two hybrid 9733768 - X 2 P61966-2 O75843 two hybrid 9733768 - X 2 O75843 two hybrid 15231747 - X 2 O75843 two hybrid 15231747 - X 2 Q15276-2 O75843 in vitro 12505986 - X 2 Q15276-2 O75843 in vitro 12505986 - X 2 O75843 in vivo 12505986 - C 3 O75843 in vivo 12505986 - C 3 O75843 in vivo 12505986 - C 3 Q9UMZ2-4 O75843 in vitro 10477754 - X 2 Q9UMZ2-4 O75843 in vitro 10477754 - X 2 P56377 O75843 two hybrid 9733768 - X 2 P56377 O75843 two hybrid 9733768 - X 2 O75843 Q6ULP2-5 two hybrid 14665628 - X 2 O75843 Q6ULP2-5 two hybrid 14665628 - X 2 O75843 tandem affinity purification 24725412 association C 161 Q9H832 O75843 two hybrid 19549727 physical association X 2 Q8IZH2 O75843 two hybrid 15231747 physical association X 2 Q5NI89 O75843 two hybrid pooling approach 20711500 physical association X 2 O75843 Q9ZC68 two hybrid pooling approach 20711500 physical association X 2 O75843 O60341 two hybrid 23455924 physical association X 2 O18973 O75843 pull down 12505986 physical association X 2 Q81Q32 O75843 two hybrid pooling approach 20711500 physical association X 2 Q96LA8 O75843 two hybrid 23455924 physical association X 2 P61967 O75843 two hybrid 9733768 physical association X 2 Q15276 O75843 two hybrid 12505986 physical association X 2 Q15276 O75843 affinity chromatography technology 12505986 physical association X 2 Q9DB50 O75843 two hybrid 9733768 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B AP1G2 SYNRG MI:0018(two hybrid)|MI:0018(two hybrid) 10477754,10814529 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_12480|BIOGRID_102082 -|bait -|prey AP1G2 ATXN1L MI:0018(two hybrid) 16713569 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_215726 prey bait AP1G2 UBC MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21139048,21890473,21906983,22505724,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_179838|BIOGRID_170606|BIOGRID_225424|BIOGRID_270118|BIOGRID_173723 prey|prey|prey|prey|prey bait|bait|bait|bait|bait AP1G2 AFTPH MI:0018(two hybrid) 14665628 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_12482 - - KDM1A AP1G2 MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 23455924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_297308|UniProt_129286 prey|bait bait|prey AP1G2 AP1S2 MI:0018(two hybrid)|MI:0018(two hybrid) 9733768 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|- (biogrid)|MI:0468(hprd) BIOGRID_77933|HPRD_12470 prey|- bait|- AP1G2 NRF1 MI:0428(imaging technique) 24250222 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization) (biogrid) BIOGRID_296486 prey bait AP1G2 NEDD4 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 18772139 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_116452|BIOGRID_116451|BIOGRID_116450 prey|prey|bait bait|bait|prey AP1G2 EGFR MI:0004(affinity chromatography technology) 23956138 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_284965 prey bait AP1G2 RABEP1 MI:0492(in vitro)|MI:0096(pull down)|MI:0096(pull down)|MI:0492(in vitro) 12505986 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0915(physical association)|- MI:0468(hprd)|(intact)|(intact)|MI:0468(hprd) HPRD_12479|UniProt_72162|UniProt_72164|HPRD_39212 -|bait|prey|- -|prey|bait|- AP1G2 AP1S1 MI:0018(two hybrid)|MI:0018(two hybrid) 9733768 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction) MI:0468(hprd)|(biogrid) HPRD_12466|BIOGRID_77930 -|prey -|bait AP1G2 PRMT6 MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 23455924 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_297309|UniProt_129288 bait|prey prey|bait AP1G2 XRN1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231747 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association) MI:0468(hprd)|(biogrid)|(intact) HPRD_12481|BIOGRID_77934|UniProt_76876 -|prey|prey -|bait|bait AP1G2 RAB5A MI:0004(affinity chromatography technology) 14665628 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_87281 prey bait AP1G2 UBE2Z MI:0018(two hybrid) 19549727 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (intact) UniProt_100946 prey bait

PPI - HINT Gene A Gene B PMID Method Quality AP1G2 AP1S2 26496610 0007 HT AP1G2 AP1S2 26496610 0007 HT B4E2K3 AP1G2 15231747 0018 HT KDM1A AP1G2 23455924 0018 HT AP1G2 RAB5A 14665628 0018 LC AP1G2 NEDD4 18772139,18772139 0415,0004 LC AP1G2 AP1S2 9733768 0018 LC AP1G2 AP1S1 9733768 0018 LC AP1G2 RABEP1 12505986,12505986 0018,0004 LC AP1G2 AFTPH 14665628 0018 LC AP1G2 XRN1 15231747 0018 HT AP1G2 PRMT6 23455924 0018 HT AP1G2 UBE2Z 19549727 0018 HT AP1G2 SYNRG 10814529 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5NI89 O75843 LYSU AP1G2 0.126 20711500 Q5S007 O75843 LRRK2 AP1G2 0.126 24725412 P61966 O75843 AP1S1 AP1G2 0.309 9733768 P61967 O75843 AP1S1 AP1G2 0.309 9733768 Q8IZH2 O75843 XRN1 AP1G2 0.332 15231747 Q8N205 O75843 SYNE4 AP1G2 0.126 26186194 Q9H832 O75843 UBE2Z AP1G2 0.183 19549727 O75843 O60341 AP1G2 KDM1A 0.332 23455924 O75843 O18973 AP1G2 RABGEF1 0.21 12505986 Q9Y6Q5 O75843 AP1M2 AP1G2 0.126 26186194 P46934 O75843 NEDD4 AP1G2 0.569 18772139 Q15276 O75843 RABEP1 AP1G2 0.623 14665628,12505986 Q9BS16 O75843 CENPK AP1G2 0.183 25416956 Q9UMZ2 O75843 SYNRG AP1G2 0.309 10814529 Q9ZC68 O75843 ASTD AP1G2 0.126 20711500 P0C7T5 O75843 ATXN1L AP1G2 0.183 16713569 Q6PD74 O75843 AAGAB AP1G2 0.126 26186194 Q6P5F9 O75843 XPO1 AP1G2 0.126 26673895 P00533 O75843 EGFR AP1G2 0.126 23956138 P56377 O75843 AP1S2 AP1G2 0.472 26496610,9733768 Q96CW1 O75843 AP2M1 AP1G2 0.126 26186194 Q96LA8 O75843 PRMT6 AP1G2 0.332 23455924 Q9DB50 O75843 AP1S2 AP1G2 0.309 9733768 P53990 O75843 IST1 AP1G2 0.081 26344197 O75843 A0A0F7RBN8 AP1G2 LIP1 {ECO:0000313|EMBL:BAR76676.1} 0.126 20711500

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 TUBAL3 AP1G2 MI:0362 inference MI:0461 interaction database HGS AP1G2 MI:0362 inference MI:1106 pathways database XPO1 AP1G2 MI:0045 experimental interaction detection MI:0461 interaction database CHMP2A AP1G2 MI:0362 inference MI:1106 pathways database IDH3B AP1G2 MI:0362 inference MI:0461 interaction database KDM1A AP1G2 MI:0045 experimental interaction detection MI:0461 interaction database DNAJA2 AP1G2 MI:0362 inference MI:0461 interaction database AP1G2 DNAJB5 MI:0362 inference MI:0461 interaction database AP1G2 GFPT2 MI:0362 inference MI:0461 interaction database AP1G2 HSPA4L MI:0362 inference MI:0461 interaction database AP1G2 EGFR MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 TUBB4A MI:0362 inference MI:0461 interaction database AP1G2 GAPDH MI:0362 inference MI:0461 interaction database AP1G2 GPI MI:0362 inference MI:0461 interaction database AP1G2 TUBB MI:0362 inference MI:0461 interaction database AP1G2 HSP90AA1 MI:0362 inference MI:0461 interaction database AP1G2 GALT MI:0362 inference MI:0461 interaction database AP1G2 HSP90AB1 MI:0362 inference MI:0461 interaction database AP1G2 ATXN1L MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 UBC MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 HSPA1A MI:0362 inference MI:0461 interaction database AP1G2 HSPA1B MI:0362 inference MI:0461 interaction database AP1G2 HSPA5 MI:0362 inference MI:0461 interaction database AP1G2 HSPA8 MI:0362 inference MI:0461 interaction database AP1G2 MTHFD1 MI:0362 inference MI:0461 interaction database AP1G2 PABPC1 MI:0362 inference MI:0461 interaction database AP1G2 PKM MI:0362 inference MI:0461 interaction database AP1G2 ATP6V1B1 MI:0362 inference MI:0461 interaction database AP1G2 HSPA6 MI:0362 inference MI:0461 interaction database AP1G2 PRKACA MI:0362 inference MI:0461 interaction database AP1G2 CTPS1 MI:0362 inference MI:0461 interaction database AP1G2 RCC1 MI:0362 inference MI:0461 interaction database AP1G2 RAB5A MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 ATP6V1B2 MI:0362 inference MI:0461 interaction database AP1G2 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 GART MI:0362 inference MI:0461 interaction database AP1G2 PRKACG MI:0362 inference MI:0461 interaction database AP1G2 PRKACB MI:0362 inference MI:0461 interaction database AP1G2 DNAJB1 MI:0362 inference MI:0461 interaction database AP1G2 PKLR MI:0362 inference MI:0461 interaction database AP1G2 MAT2A MI:0362 inference MI:0461 interaction database AP1G2 DNAJA1 MI:0362 inference MI:0461 interaction database AP1G2 HSPA1L MI:0362 inference MI:0461 interaction database AP1G2 HSPA4 MI:0362 inference MI:0461 interaction database AP1G2 RPL4 MI:0362 inference MI:0461 interaction database AP1G2 HSPA9 MI:0362 inference MI:0461 interaction database AP1G2 NEDD4 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 TUFM MI:0362 inference MI:0461 interaction database AP1G2 IDH3G MI:0362 inference MI:0461 interaction database AP1G2 PRKX MI:0362 inference MI:0461 interaction database AP1G2 CLTCL1 MI:0362 inference MI:0461 interaction database AP1G2 AP2S1 MI:0362 inference MI:0461 interaction database AP1G2 PRKAA2 MI:0362 inference MI:0461 interaction database AP1G2 HSPA2 MI:0362 inference MI:0461 interaction database AP1G2 AP1S2 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 EIF6 MI:0362 inference MI:0461 interaction database AP1G2 DNAJB13 MI:0362 inference MI:0461 interaction database AP1G2 UBE2G2 MI:0362 inference MI:0461 interaction database AP1G2 AP1S1 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 YWHAE MI:0362 inference MI:0461 interaction database AP1G2 AP2B1 MI:0362 inference MI:0461 interaction database AP1G2 SUMO1 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 EEF1A1 MI:0362 inference MI:0461 interaction database AP1G2 TUBA1B MI:0362 inference MI:0461 interaction database AP1G2 TUBA4A MI:0362 inference MI:0461 interaction database AP1G2 TUBB4B MI:0362 inference MI:0461 interaction database AP1G2 HIST1H3A MI:0362 inference MI:0461 interaction database AP1G2 CCT2 MI:0362 inference MI:0461 interaction database AP1G2 H3F3A MI:0362 inference MI:0461 interaction database AP1G2 MAT1A MI:0362 inference MI:0461 interaction database AP1G2 CLTC MI:0362 inference MI:0461 interaction database AP1G2 EEF1A2 MI:0362 inference MI:0461 interaction database AP1G2 GFPT1 MI:0362 inference MI:0461 interaction database AP1G2 VAC14 MI:0362 inference MI:0461 interaction database AP1G2 AP1B1 MI:0362 inference MI:0461 interaction database AP1G2 PSMD2 MI:0362 inference MI:0461 interaction database AP1G2 MAD2L1 MI:0362 inference MI:0461 interaction database AP1G2 PABPC4 MI:0362 inference MI:0461 interaction database AP1G2 TUBB3 MI:0362 inference MI:0461 interaction database AP1G2 KRR1 MI:0362 inference MI:0461 interaction database AP1G2 PWP1 MI:0362 inference MI:0461 interaction database AP1G2 TUBA3C MI:0362 inference MI:0461 interaction database AP1G2 TUBB2A MI:0362 inference MI:0461 interaction database AP1G2 TRIP12 MI:0362 inference MI:0461 interaction database AP1G2 RABEP1 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 HIST3H3 MI:0362 inference MI:0461 interaction database AP1G2 TUBB8 MI:0362 inference MI:0461 interaction database AP1G2 PABPC1L MI:0362 inference MI:0461 interaction database AP1G2 PABPC1L2A MI:0362 inference MI:0461 interaction database AP1G2 LRRK2 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 H3F3C MI:0362 inference MI:0461 interaction database AP1G2 AAGAB MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 TUBA3E MI:0362 inference MI:0461 interaction database AP1G2 HIST2H3A MI:0362 inference MI:0461 interaction database AP1G2 TUBA1A MI:0362 inference MI:0461 interaction database AP1G2 XRN1 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 SYNE4 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 KRI1 MI:0362 inference MI:0461 interaction database AP1G2 DDX55 MI:0362 inference MI:0461 interaction database AP1G2 BRIX1 MI:0362 inference MI:0461 interaction database AP1G2 IPO4 MI:0362 inference MI:0461 interaction database AP1G2 DNAJA4 MI:0362 inference MI:0461 interaction database AP1G2 HSPH1 MI:0362 inference MI:0461 interaction database AP1G2 AP2M1 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 PABPC5 MI:0362 inference MI:0461 interaction database AP1G2 PRMT6 MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 AP1S3 MI:0362 inference MI:0461 interaction database AP1G2 NMNAT3 MI:0362 inference MI:0461 interaction database AP1G2 CENPK MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 TUBB6 MI:0362 inference MI:0461 interaction database AP1G2 TUBB2B MI:0362 inference MI:0461 interaction database AP1G2 AP1M1 MI:0362 inference MI:0461 interaction database AP1G2 GTPBP4 MI:0362 inference MI:0461 interaction database AP1G2 NMNAT2 MI:0362 inference MI:0461 interaction database AP1G2 NAT10 MI:0362 inference MI:0461 interaction database AP1G2 PABPC3 MI:0362 inference MI:0461 interaction database AP1G2 TUBB1 MI:0362 inference MI:0461 interaction database AP1G2 UBE2Z MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 WDR76 MI:0362 inference MI:0461 interaction database AP1G2 POLR1B MI:0362 inference MI:0461 interaction database AP1G2 NMNAT1 MI:0362 inference MI:0461 interaction database AP1G2 UPF2 MI:0362 inference MI:0461 interaction database AP1G2 UTP3 MI:0362 inference MI:0461 interaction database AP1G2 CTPS2 MI:0362 inference MI:0461 interaction database AP1G2 RBM28 MI:0362 inference MI:0461 interaction database AP1G2 TUBA8 MI:0362 inference MI:0461 interaction database AP1G2 DNAJB4 MI:0362 inference MI:0461 interaction database AP1G2 RABGEF1 MI:0362 inference MI:0461 interaction database AP1G2 SYNRG MI:0045 experimental interaction detection MI:0461 interaction database AP1G2 DUSP12 MI:0362 inference MI:0461 interaction database AP1G2 RCL1 MI:0362 inference MI:0461 interaction database AP1G2 GMPPB MI:0362 inference MI:0461 interaction database AP1G2 AP1M2 MI:0045 experimental interaction detection MI:0461 interaction database