Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 6 28876509 rs2269553 G A rs2269553 5.33E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_drug 6 28897633 rs1233508 G T rs1233508 7.27E-04 ALDOSTERONE BIOLOGICAL MARKERS|NATRIURETIC PEPTIDE, BRAIN|RENIN Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A nearGene-5 GWASdb_drug 6 28872446 rs209126 T C rs209126 2.44E-08 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 6 28876509 rs2269553 G A rs2269553 1.23E-06 Amyotrophic Lateral Sclerosis HPOID:0007354 DOID:332 G intron GWASdb_trait 6 28876509 rs2269553 G A rs2269553 5.33E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 G intron GWASdb_trait 6 28876509 rs2269553 G A rs2269553 3.66E-05 Coronary heart disease HPOID:0001677 DOID:3393 G intron GWASdb_trait 6 28881660 rs209121 T C rs209121 7.67E-04 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 6 28891839 rs3131102 G A rs3131102 1.97E-07 Multiple complex diseases HPOID:0000118 NA A nearGene-5 GWASdb_trait 6 28897633 rs1233508 G T rs1233508 7.27E-04 Blood pressure, CVD RF and other traits (body mass index (BMI), waist:hip ratio, renin activity in plasma, aldosterone concentration in plasma, BNP levels in plasma, alcohol consumption) HPOID:0011025 DOID:10763 A nearGene-5 GWASdb_trait 6 28897980 rs3135318 T C rs3135318 8.07E-06 Pulmonary function HPOID:0002795 DOID:2841|DOID:3083 A nearGene-5 GWASdb_trait