Mutation - ICGC Project Code Chromosome Chromosome Start Chromosome End Mutation Type Mutated from Allele Mutated to Allele Consequence Type AA Mutation CDS Mutation BLCA-CN 14 24682722 24682722 single base substitution A C downstream_gene_variant BLCA-CN 14 24684759 24684759 single base substitution T G splice_region_variant BLCA-CN 14 24702539 24702539 single base substitution G A upstream_gene_variant BLCA-US 14 24687356 24687356 single base substitution G A exon_variant BLCA-US 14 24687356 24687356 single base substitution G A synonymous_variant I44I 132C>T BRCA-EU 14 24679428 24679428 single base substitution C G downstream_gene_variant BRCA-EU 14 24679601 24679601 single base substitution G A downstream_gene_variant BRCA-EU 14 24682178 24682178 single base substitution G C downstream_gene_variant BRCA-EU 14 24682619 24682619 single base substitution C T downstream_gene_variant BRCA-EU 14 24682832 24682832 single base substitution G T downstream_gene_variant BRCA-EU 14 24683221 24683221 single base substitution C T 3_prime_UTR_variant BRCA-EU 14 24683221 24683221 single base substitution C T downstream_gene_variant BRCA-EU 14 24685224 24685224 single base substitution G A intron_variant BRCA-EU 14 24685651 24685651 single base substitution G C intron_variant BRCA-EU 14 24685779 24685779 single base substitution G A intron_variant BRCA-EU 14 24687375 24687375 insertion of <=200bp - G exon_variant BRCA-EU 14 24687375 24687375 insertion of <=200bp - G frameshift_variant P38P? BRCA-EU 14 24688405 24688405 single base substitution C T intron_variant BRCA-EU 14 24692073 24692073 single base substitution C T intron_variant BRCA-EU 14 24692606 24692606 deletion of <=200bp A - intron_variant BRCA-EU 14 24693294 24693294 single base substitution C G intron_variant BRCA-EU 14 24694594 24694594 single base substitution G A intron_variant BRCA-EU 14 24697325 24697325 single base substitution C T intron_variant BRCA-EU 14 24697773 24697773 single base substitution T C intron_variant BRCA-EU 14 24698524 24698524 single base substitution C G intron_variant BRCA-EU 14 24699190 24699190 single base substitution C T intron_variant BRCA-EU 14 24700613 24700616 deletion of <=200bp AAAT - intron_variant BRCA-EU 14 24700871 24700871 deletion of <=200bp G - exon_variant BRCA-EU 14 24700871 24700871 deletion of <=200bp G - intron_variant BRCA-EU 14 24701267 24701267 single base substitution G A intron_variant BRCA-EU 14 24701605 24701605 single base substitution C T upstream_gene_variant BRCA-EU 14 24701752 24701752 single base substitution G C upstream_gene_variant BRCA-EU 14 24704359 24704359 single base substitution G A upstream_gene_variant BRCA-EU 14 24704799 24704799 single base substitution C G upstream_gene_variant BRCA-EU 14 24704846 24704846 single base substitution T G upstream_gene_variant BRCA-FR 14 24683221 24683221 single base substitution C T 3_prime_UTR_variant BRCA-FR 14 24683221 24683221 single base substitution C T downstream_gene_variant BRCA-FR 14 24683734 24683734 single base substitution T G 3_prime_UTR_variant BRCA-FR 14 24683734 24683734 single base substitution T G exon_variant BRCA-FR 14 24683734 24683734 single base substitution T G missense_variant E111A 332A>C BRCA-FR 14 24685224 24685224 single base substitution G A intron_variant BRCA-FR 14 24685779 24685779 single base substitution G A intron_variant BRCA-FR 14 24692073 24692073 single base substitution C T intron_variant BRCA-FR 14 24694594 24694594 single base substitution G A intron_variant BRCA-FR 14 24696851 24696851 single base substitution G A intron_variant BRCA-FR 14 24698524 24698524 single base substitution C G intron_variant BRCA-FR 14 24701267 24701267 single base substitution G A intron_variant BRCA-FR 14 24704359 24704359 single base substitution G A upstream_gene_variant BRCA-UK 14 24680901 24680901 single base substitution T C downstream_gene_variant BRCA-UK 14 24685135 24685135 single base substitution G A intron_variant BRCA-UK 14 24692511 24692511 single base substitution G A intron_variant BRCA-US 14 24680890 24680890 single base substitution C G downstream_gene_variant BRCA-US 14 24683340 24683340 single base substitution T C 3_prime_UTR_variant BRCA-US 14 24683340 24683340 single base substitution T C downstream_gene_variant BRCA-US 14 24683340 24683340 single base substitution T C missense_variant I158V 472A>G BRCA-US 14 24683764 24683764 single base substitution A C 3_prime_UTR_variant BRCA-US 14 24683764 24683764 single base substitution A C exon_variant BRCA-US 14 24683764 24683764 single base substitution A C missense_variant F101C 302T>G BRCA-US 14 24684867 24684867 single base substitution C T missense_variant D51N 151G>A BRCA-US 14 24684867 24684867 single base substitution C T splice_region_variant BRCA-US 14 24687410 24687410 single base substitution G C exon_variant BRCA-US 14 24687410 24687410 single base substitution G C missense_variant I26M 78C>G BRCA-US 14 24702445 24702445 single base substitution C T upstream_gene_variant BTCA-JP 14 24683427 24683433 deletion of <=200bp TGCCACC - downstream_gene_variant BTCA-JP 14 24683427 24683433 deletion of <=200bp TGCCACC - intron_variant BTCA-JP 14 24686450 24686450 deletion of <=200bp A - intron_variant BTCA-JP 14 24686510 24686510 single base substitution G T intron_variant BTCA-JP 14 24702832 24702832 single base substitution A G upstream_gene_variant CESC-US 14 24683549 24683549 single base substitution C G 3_prime_UTR_variant CESC-US 14 24683549 24683549 single base substitution C G downstream_gene_variant CESC-US 14 24683549 24683549 single base substitution C G missense_variant E141Q 421G>C CESC-US 14 24684984 24684984 single base substitution G A exon_variant CESC-US 14 24684984 24684984 single base substitution G A intron_variant CLLE-ES 14 24698088 24698088 single base substitution C G intron_variant COAD-US 14 24684996 24684996 single base substitution A C exon_variant COAD-US 14 24684996 24684996 single base substitution A C intron_variant COCA-CN 14 24680920 24680920 single base substitution T G downstream_gene_variant COCA-CN 14 24681054 24681054 single base substitution T C downstream_gene_variant COCA-CN 14 24685131 24685131 single base substitution C A intron_variant COCA-CN 14 24686420 24686420 single base substitution C A exon_variant COCA-CN 14 24686420 24686420 single base substitution C A intron_variant COCA-CN 14 24687604 24687604 single base substitution C G exon_variant COCA-CN 14 24687604 24687604 single base substitution C G missense_variant E18Q 52G>C COCA-CN 14 24702979 24702979 single base substitution C G upstream_gene_variant COCA-CN 14 24703270 24703270 single base substitution G T upstream_gene_variant COCA-CN 14 24705034 24705034 single base substitution T G upstream_gene_variant COCA-CN 14 24706174 24706174 single base substitution C A upstream_gene_variant COCA-CN 14 24706504 24706504 single base substitution G A upstream_gene_variant ESAD-UK 14 24682159 24682159 single base substitution G T downstream_gene_variant ESAD-UK 14 24682301 24682301 single base substitution C G downstream_gene_variant ESAD-UK 14 24682412 24682412 single base substitution G A downstream_gene_variant ESAD-UK 14 24688265 24688265 single base substitution A T intron_variant ESAD-UK 14 24691452 24691452 deletion of <=200bp A - intron_variant ESAD-UK 14 24691523 24691523 single base substitution T C intron_variant ESAD-UK 14 24693884 24693884 single base substitution A G intron_variant ESAD-UK 14 24694131 24694131 single base substitution G A intron_variant ESAD-UK 14 24694268 24694268 single base substitution G A intron_variant ESAD-UK 14 24696672 24696672 single base substitution C T intron_variant ESAD-UK 14 24700504 24700504 single base substitution T G intron_variant ESAD-UK 14 24700838 24700838 single base substitution C T intron_variant ESCA-CN 14 24686388 24686388 single base substitution C G intron_variant ESCA-CN 14 24686388 24686388 single base substitution C G splice_region_variant GBM-US 14 24683351 24683351 single base substitution G A 3_prime_UTR_variant GBM-US 14 24683351 24683351 single base substitution G A downstream_gene_variant GBM-US 14 24683351 24683351 single base substitution G A missense_variant T154I 461C>T LAML-KR 14 24683125 24683125 single base substitution A G downstream_gene_variant LAML-KR 14 24695231 24695231 single base substitution T G intron_variant LAML-KR 14 24705295 24705295 single base substitution T C upstream_gene_variant LICA-FR 14 24695652 24695653 deletion of <=200bp AA - intron_variant LINC-JP 14 24678825 24678840 deletion of <=200bp ATCTGCCCAGTTTTAT - downstream_gene_variant LINC-JP 14 24687512 24687512 single base substitution A G intron_variant LINC-JP 14 24702766 24702766 insertion of <=200bp - A upstream_gene_variant LINC-JP 14 24703372 24703372 single base substitution C G upstream_gene_variant LINC-JP 14 24703773 24703773 single base substitution A G upstream_gene_variant LINC-JP 14 24704355 24704355 single base substitution A C upstream_gene_variant LIRI-JP 14 24678904 24678904 single base substitution A C downstream_gene_variant LIRI-JP 14 24679414 24679414 single base substitution T C downstream_gene_variant LIRI-JP 14 24681294 24681294 single base substitution A G downstream_gene_variant LIRI-JP 14 24684073 24684073 single base substitution C G intron_variant LIRI-JP 14 24685213 24685213 single base substitution T C intron_variant LIRI-JP 14 24687873 24687873 single base substitution C A intron_variant LIRI-JP 14 24688990 24688990 single base substitution G A intron_variant LIRI-JP 14 24692189 24692189 single base substitution G T intron_variant LIRI-JP 14 24696078 24696078 single base substitution A C intron_variant LIRI-JP 14 24699008 24699008 single base substitution G A intron_variant LIRI-JP 14 24699149 24699149 single base substitution C T intron_variant LIRI-JP 14 24701871 24701871 single base substitution A T upstream_gene_variant LIRI-JP 14 24702401 24702401 single base substitution T G upstream_gene_variant LIRI-JP 14 24705931 24705931 single base substitution A G upstream_gene_variant LIRI-JP 14 24706001 24706001 single base substitution G A upstream_gene_variant LUSC-KR 14 24678885 24678885 single base substitution A C downstream_gene_variant LUSC-KR 14 24680005 24680005 single base substitution C T downstream_gene_variant LUSC-KR 14 24687771 24687771 single base substitution G A intron_variant LUSC-KR 14 24688023 24688023 single base substitution G A intron_variant LUSC-KR 14 24689246 24689246 single base substitution G A intron_variant LUSC-KR 14 24692945 24692945 single base substitution A T intron_variant LUSC-KR 14 24697059 24697059 single base substitution G T intron_variant LUSC-KR 14 24700194 24700194 single base substitution C T intron_variant LUSC-KR 14 24700712 24700712 single base substitution T G intron_variant LUSC-US 14 24684816 24684816 single base substitution C A 3_prime_UTR_variant LUSC-US 14 24684816 24684816 single base substitution C A exon_variant LUSC-US 14 24684816 24684816 single base substitution C A missense_variant V68L 202G>T MALY-DE 14 24681701 24681701 single base substitution T A downstream_gene_variant MALY-DE 14 24683695 24683695 single base substitution T C splice_region_variant MALY-DE 14 24684755 24684755 single base substitution T C splice_region_variant MALY-DE 14 24692872 24692872 single base substitution A C intron_variant MALY-DE 14 24696288 24696288 single base substitution A G intron_variant MALY-DE 14 24696311 24696311 single base substitution T G intron_variant MELA-AU 14 24679260 24679260 single base substitution C A downstream_gene_variant MELA-AU 14 24679720 24679720 single base substitution G A downstream_gene_variant MELA-AU 14 24680174 24680174 single base substitution G A downstream_gene_variant MELA-AU 14 24680316 24680316 single base substitution G A downstream_gene_variant MELA-AU 14 24680824 24680824 single base substitution C T downstream_gene_variant MELA-AU 14 24681051 24681051 single base substitution G A downstream_gene_variant MELA-AU 14 24682560 24682560 single base substitution C T downstream_gene_variant MELA-AU 14 24682731 24682731 single base substitution G A downstream_gene_variant MELA-AU 14 24683082 24683082 single base substitution C T downstream_gene_variant MELA-AU 14 24684988 24684989 multiple base substitution (>=2bp and <=200bp) GG TA exon_variant MELA-AU 14 24684988 24684989 multiple base substitution (>=2bp and <=200bp) GG TA intron_variant MELA-AU 14 24685776 24685776 single base substitution G A intron_variant MELA-AU 14 24686176 24686176 single base substitution G A intron_variant MELA-AU 14 24686435 24686435 single base substitution G A intron_variant MELA-AU 14 24686435 24686435 single base substitution G A splice_region_variant MELA-AU 14 24687380 24687380 single base substitution G A exon_variant MELA-AU 14 24687380 24687380 single base substitution G A synonymous_variant I36I 108C>T MELA-AU 14 24687477 24687477 single base substitution G A intron_variant MELA-AU 14 24687600 24687601 multiple base substitution (>=2bp and <=200bp) GG AA exon_variant MELA-AU 14 24687600 24687601 multiple base substitution (>=2bp and <=200bp) GG AA missense_variant P19F 55CC>TT MELA-AU 14 24687975 24687976 multiple base substitution (>=2bp and <=200bp) GG AA intron_variant MELA-AU 14 24688231 24688231 single base substitution G A intron_variant MELA-AU 14 24688374 24688374 single base substitution A G intron_variant MELA-AU 14 24688400 24688400 single base substitution G A intron_variant MELA-AU 14 24689597 24689597 single base substitution G A intron_variant MELA-AU 14 24690014 24690014 single base substitution G A intron_variant MELA-AU 14 24690128 24690128 single base substitution G A intron_variant MELA-AU 14 24690311 24690311 single base substitution G A intron_variant MELA-AU 14 24690628 24690628 single base substitution G A intron_variant MELA-AU 14 24690835 24690835 single base substitution C T intron_variant MELA-AU 14 24690965 24690965 single base substitution G A intron_variant MELA-AU 14 24691115 24691115 single base substitution G A intron_variant MELA-AU 14 24692476 24692476 single base substitution G A intron_variant MELA-AU 14 24692588 24692588 single base substitution G A intron_variant MELA-AU 14 24692590 24692590 single base substitution G A intron_variant MELA-AU 14 24692746 24692746 single base substitution T C intron_variant MELA-AU 14 24692984 24692984 single base substitution C T intron_variant MELA-AU 14 24693182 24693182 single base substitution G A intron_variant MELA-AU 14 24693761 24693761 single base substitution C T intron_variant MELA-AU 14 24694714 24694714 single base substitution G A intron_variant MELA-AU 14 24695161 24695161 single base substitution C A intron_variant MELA-AU 14 24695163 24695163 single base substitution T A intron_variant MELA-AU 14 24696116 24696116 single base substitution A C intron_variant MELA-AU 14 24696156 24696156 single base substitution G A intron_variant MELA-AU 14 24696529 24696529 single base substitution G A intron_variant MELA-AU 14 24696630 24696630 single base substitution G A intron_variant MELA-AU 14 24697993 24697993 single base substitution T C intron_variant MELA-AU 14 24698860 24698860 single base substitution G A intron_variant MELA-AU 14 24698871 24698871 single base substitution A G intron_variant MELA-AU 14 24699986 24699986 single base substitution G A intron_variant MELA-AU 14 24701578 24701578 single base substitution C T upstream_gene_variant MELA-AU 14 24704419 24704419 single base substitution G A upstream_gene_variant MELA-AU 14 24706169 24706170 multiple base substitution (>=2bp and <=200bp) CC TT upstream_gene_variant OV-AU 14 24680174 24680174 single base substitution G C downstream_gene_variant OV-AU 14 24680366 24680366 single base substitution G C downstream_gene_variant OV-AU 14 24681576 24681576 single base substitution C G downstream_gene_variant OV-AU 14 24684921 24684921 single base substitution G T intron_variant OV-AU 14 24685537 24685537 single base substitution T C intron_variant OV-AU 14 24694264 24694264 single base substitution C G intron_variant OV-AU 14 24695264 24695264 single base substitution A C intron_variant OV-AU 14 24703022 24703022 single base substitution T G upstream_gene_variant PACA-AU 14 24678724 24678726 deletion of <=200bp CCC - downstream_gene_variant PACA-AU 14 24681817 24681817 single base substitution T C downstream_gene_variant PACA-AU 14 24684475 24684475 single base substitution A G intron_variant PACA-AU 14 24694227 24694227 single base substitution T C intron_variant PACA-AU 14 24696698 24696698 single base substitution G A intron_variant PACA-AU 14 24699184 24699184 single base substitution G A intron_variant PACA-AU 14 24699522 24699522 single base substitution C T intron_variant PACA-CA 14 24678913 24678913 single base substitution T C downstream_gene_variant PACA-CA 14 24688410 24688410 single base substitution G A intron_variant PACA-CA 14 24692749 24692749 single base substitution A T intron_variant PACA-CA 14 24704861 24704861 single base substitution C G upstream_gene_variant PACA-CA 14 24704864 24704864 single base substitution A C upstream_gene_variant PACA-CA 14 24704937 24704937 single base substitution C G upstream_gene_variant PACA-CA 14 24705553 24705553 single base substitution T C upstream_gene_variant PAEN-AU 14 24695637 24695637 single base substitution G C intron_variant PBCA-DE 14 24687403 24687403 single base substitution G A exon_variant PBCA-DE 14 24687403 24687403 single base substitution G A missense_variant R29C 85C>T PBCA-DE 14 24696711 24696711 single base substitution G C intron_variant PRAD-CA 14 24693643 24693643 single base substitution C G intron_variant PRAD-UK 14 24680412 24680412 deletion of <=200bp A - downstream_gene_variant PRAD-UK 14 24686652 24686652 single base substitution C T intron_variant PRAD-US 14 24682652 24682652 single base substitution C G downstream_gene_variant PRAD-US 14 24702732 24702732 single base substitution C A upstream_gene_variant READ-US 14 24679894 24679894 single base substitution G T downstream_gene_variant READ-US 14 24680711 24680711 single base substitution C T downstream_gene_variant READ-US 14 24683287 24683287 single base substitution C T 3_prime_UTR_variant READ-US 14 24683287 24683287 single base substitution C T downstream_gene_variant READ-US 14 24683741 24683741 single base substitution G T 3_prime_UTR_variant READ-US 14 24683741 24683741 single base substitution G T exon_variant READ-US 14 24683741 24683741 single base substitution G T missense_variant H109N 325C>A READ-US 14 24706350 24706350 single base substitution T G upstream_gene_variant RECA-EU 14 24682705 24682705 single base substitution T A downstream_gene_variant RECA-EU 14 24685655 24685655 single base substitution G A intron_variant RECA-EU 14 24698109 24698109 single base substitution A T intron_variant SKCA-BR 14 24681486 24681486 single base substitution A C downstream_gene_variant SKCA-BR 14 24681755 24681755 single base substitution A C downstream_gene_variant SKCA-BR 14 24682636 24682636 single base substitution G C downstream_gene_variant SKCA-BR 14 24684638 24684638 single base substitution G A intron_variant SKCA-BR 14 24686436 24686436 single base substitution G A intron_variant SKCA-BR 14 24686436 24686436 single base substitution G A splice_region_variant SKCA-BR 14 24687457 24687457 single base substitution G A intron_variant SKCA-BR 14 24692932 24692932 insertion of <=200bp - GA intron_variant SKCA-BR 14 24693513 24693513 single base substitution A C intron_variant SKCA-BR 14 24694377 24694377 insertion of <=200bp - CA intron_variant SKCA-BR 14 24702453 24702453 single base substitution A G upstream_gene_variant SKCM-US 14 24680673 24680673 single base substitution G A downstream_gene_variant SKCM-US 14 24682669 24682669 single base substitution C A downstream_gene_variant SKCM-US 14 24682688 24682688 single base substitution G A downstream_gene_variant SKCM-US 14 24684863 24684863 single base substitution C T 3_prime_UTR_variant SKCM-US 14 24684863 24684863 single base substitution C T exon_variant SKCM-US 14 24684863 24684863 single base substitution C T missense_variant G52E 155G>A SKCM-US 14 24701578 24701578 single base substitution C T upstream_gene_variant SKCM-US 14 24706339 24706339 single base substitution C T upstream_gene_variant STAD-US 14 24679618 24679618 single base substitution G A downstream_gene_variant STAD-US 14 24705334 24705334 single base substitution G A upstream_gene_variant UCEC-US 14 24680896 24680896 single base substitution C A downstream_gene_variant UCEC-US 14 24683240 24683240 single base substitution A C 3_prime_UTR_variant UCEC-US 14 24683240 24683240 single base substitution A C downstream_gene_variant UCEC-US 14 24683257 24683257 single base substitution G A 3_prime_UTR_variant UCEC-US 14 24683257 24683257 single base substitution G A downstream_gene_variant UCEC-US 14 24683309 24683309 single base substitution C T 3_prime_UTR_variant UCEC-US 14 24683309 24683309 single base substitution C T downstream_gene_variant UCEC-US 14 24683309 24683309 single base substitution C T missense_variant S168N 503G>A UCEC-US 14 24686360 24686360 single base substitution C G intron_variant UCEC-US 14 24702774 24702774 single base substitution C T upstream_gene_variant UCEC-US 14 24704989 24704989 single base substitution G C upstream_gene_variant UCEC-US 14 24706542 24706542 single base substitution A T upstream_gene_variant

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer A C Missense p.F101C c.302T>G 14 24683764 BRCA C A Missense p.R58L c.173G>T 14 24684845 LUAD C T Missense p.R25Q c.74G>A 14 24687414 LUAD C T Missense p.V23M c.67G>A 14 24687421 LUAD G A Missense p.P37S c.109C>T 14 24687379 CM G A Missense p.P66S c.196C>T 14 24684822 CM G A Missense p.R29C c.85C>T 14 24687403 MB G A Missense p.T154I c.461C>T 14 24683351 GBM G C Missense p.I26M c.78C>G 14 24687410 BRCA G T Missense p.F104L c.312C>A 14 24683754 LUAD T C Missense p.I158V c.472A>G 14 24683340 BRCA