Disease associated variation - GWASdb Chr Pos SNP ID(dbSNP 142) Ref Alt Ori SNP ID P-value Drug Name Drug Anno GWAS Trait HPO ID DO ID AA Type Trait or Drug 2 53954681 rs6705712 C G rs6705712 5.69E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 G intron GWASdb_drug 2 53958136 rs10188142 C T rs10188142 5.54E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_drug 2 53965389 rs3821081 G A rs3821081 8.03E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_drug 2 53972693 rs3770393 G A rs3770393 7.49E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_drug 2 53974223 rs12613353 T G rs12613353 8.98E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_drug 2 54056188 rs805438 T A rs805438 3.41E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 A intron GWASdb_drug 2 54056270 rs2080721 C G rs2080721 4.84E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 G intron GWASdb_drug 2 54056574 rs805439 C T rs805439 2.15E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 C intron GWASdb_drug 2 54058082 rs12617599 G C,T rs12617599 7.37E-05 TAMSULOSIN ADRENERGIC ALPHA-1 RECEPTOR ANTAGONISTS|SULFONAMIDES Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 C intron GWASdb_drug 2 53898032 rs2287512 T C rs2287512 4.90E-05 Schizophrenia HPOID:0100753 DOID:5419 T intron GWASdb_trait 2 53901897 rs7557799 A T rs7557799 8.23E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 2 53906935 rs7556791 A G rs7556791 8.53E-04 Alzheimer's disease HPOID:0002511 DOID:10652 G intron GWASdb_trait 2 53931190 rs7583622 G A rs7583622 5.26E-05 Multiple sclerosis HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 DOID:2377 G intron GWASdb_trait 2 53954681 rs6705712 C G rs6705712 8.85E-04 Multiple complex diseases HPOID:0000118 NA G intron GWASdb_trait 2 53954681 rs6705712 C G rs6705712 0.0000569 Panic disorder HPOID:0100851 DOID:594 G intron GWASdb_trait 2 53954681 rs6705712 C G rs6705712 5.69E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 G intron GWASdb_trait 2 53956980 rs6714424 C A rs6714424 1.59E-05 Lymphocyte counts HPOID:0004332|HPOID:0002665 DOID:2841|DOID:1240|DOID:0060058|DOID:614|DOID:1287 C intron GWASdb_trait 2 53958136 rs10188142 C T rs10188142 7.50E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 2 53958136 rs10188142 C T rs10188142 0.0000554 Panic disorder HPOID:0100851 DOID:594 T intron GWASdb_trait 2 53958136 rs10188142 C T rs10188142 5.54E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_trait 2 53965389 rs3821081 G A rs3821081 2.67E-04 Multiple complex diseases HPOID:0000118 NA T intron GWASdb_trait 2 53965389 rs3821081 G A rs3821081 0.0000803 Panic disorder HPOID:0100851 DOID:594 T intron GWASdb_trait 2 53965389 rs3821081 G A rs3821081 8.03E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_trait 2 53972693 rs3770393 G A rs3770393 0.0000749 Panic disorder HPOID:0100851 DOID:594 T intron GWASdb_trait 2 53972693 rs3770393 G A rs3770393 7.49E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_trait 2 53974223 rs12613353 T G rs12613353 0.0000898 Panic disorder HPOID:0100851 DOID:594 T intron GWASdb_trait 2 53974223 rs12613353 T G rs12613353 8.98E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 T intron GWASdb_trait 2 54053872 rs698853 A G rs698853 7.37E-04 Parkinson's disease HPOID:0001300 DOID:14330 G intron GWASdb_trait 2 54053872 rs698853 A G rs698853 7.11E-06 Multiple sclerosis HPOID:0000096|HPOID:0001967|HPOID:0009741|HPOID:0008664|HPOID:0001150|HPOID:0005450|HPOID:0005652|HPOID:0005686|HPOID:0005789|HPOID:0100923|HPOID:0100925|HPOID:0006623|HPOID:0100861|HPOID:0002694|HPOID:0004979|HPOID:0003881|HPOID:0003991|HPOID:0003854|HPOID:0003933|HPOID:0004030|HPOID:0100899|HPOID:0002634 DOID:2377 G intron GWASdb_trait 2 54056188 rs805438 T A rs805438 7.39E-05 Multiple complex diseases HPOID:0000118 NA A intron GWASdb_trait 2 54056188 rs805438 T A rs805438 0.0000341 Panic disorder HPOID:0100851 DOID:594 A intron GWASdb_trait 2 54056188 rs805438 T A rs805438 3.41E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 A intron GWASdb_trait 2 54056270 rs2080721 C G rs2080721 0.0000484 Panic disorder HPOID:0100851 DOID:594 G intron GWASdb_trait 2 54056270 rs2080721 C G rs2080721 4.84E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 G intron GWASdb_trait 2 54056574 rs805439 C T rs805439 9.91E-05 Multiple complex diseases HPOID:0000118 NA C intron GWASdb_trait 2 54056574 rs805439 C T rs805439 0.0000215 Panic disorder HPOID:0100851 DOID:594 C intron GWASdb_trait 2 54056574 rs805439 C T rs805439 2.15E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 C intron GWASdb_trait 2 54058082 rs12617599 G C,T rs12617599 0.0000737 Panic disorder HPOID:0100851 DOID:594 C intron GWASdb_trait 2 54058082 rs12617599 G C,T rs12617599 7.37E-05 Serum tamsulosin hydrochloride concentration HPOID:0012220 DOID:11132 C intron GWASdb_trait

Disease associated variation - GWAS Central Study Name Source Marker Accession Chromosome Marker Start Marker Stop Alleles Gene Section P-value -log(p-value) GWAS of prostate cancer rs805439 2 54056574 54056574 intronic 0.780778 0.10747243229475699