PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus SOCS7 STAT5A 15677474 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IRS4 12052866 hprd exp G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SEPT6 17803907 innatedb,biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 TUBA1A 12052866 hprd exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 TUBB4B 12052866 hprd exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PLCG1 9344857 hprd exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PIK3R2 SOCS7 12052866 hprd exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SORBS3 15242778 hprd,biogrid,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CUL5 21145461 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 EGFR 9344857, 25402006 hprd exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 INSR 16127460, 25402006, 23023127 innatedb exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NCK1 17803907,9344857, 23023127 innatedb,hprd,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IRS1 16127460, 23023127 innatedb exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GRB2 9344857, 23023127 hprd exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ABI1 20598684, 23023127 mint,intact exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 STAT3 15677474, 25402006 innatedb,biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IRS2 12052866, 23023127 hprd exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PIK3R1 12052866, 25402006, 23023127 hprd exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 LEPR 25402006 ortho, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ITCH 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 HDAC1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 C10orf35 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS7 SEPT2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 VAV1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ROBO2 23023127 pred G G G G G G G G G G SOCS7 VRK3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MAPK8IP2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RALGDS 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SNX27 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MUSK 23023127 pred G G G G G G G G G SOCS7 USP20 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SYNJ2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CHRD 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 JAK2 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ARHGEF9 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CSF3R 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 KLHL3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PRKCI 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 STXBP4 23023127 pred G G G G G G G G G G G G SOCS7 ARHGEF11 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DOCK3 25402006 pred G G G G G SOCS7 UBE2K 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 UBASH3A 23023127 pred G G SOCS7 TRIM32 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PIN1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DVL1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTPN3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SH2D5 23023127 pred G G G G G G G G G G G G G G SOCS7 FEZF2 23023127 pred G G G SOCS7 GAB1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RASGRP1 16082366 pred G G G G G G G G G G G G G G G G G G G SOCS7 RAPGEFL1 16082366 pred G G G G G G PSD SOCS7 23023127 pred G G G G G G G G G G G G G SOCS7 FGF12 23023127 pred G G G G G G G G G G G G G SOCS7 ID4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ABL1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 TSC2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 APPL1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 VPS13A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTK2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 STMN3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MAP3K9 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTK6 25402006 pred G G G G G G G G G G G G G G G G G SOCS7 MAP3K10 23023127 pred SOCS7 IL12RB2 23023127 pred G G G SOCS7 KCTD13 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IGF1R 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SLIT2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 BCAR1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CD3E 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FAM174A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WNT10B SOCS7 23023127 pred G G G G G G G G G G G G G G G G SOCS7 LNX1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CNTNAP1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IL7R 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 BRPF3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CYP4F2 25402006 pred G G G G G G G SOCS7 CRK 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RASGEF1B 16082366 pred G SOCS7 SHC3 23023127 pred G G G G G G G G G SOCS7 TEK 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CDH13 23023127 pred G G G G G G G G G G SOCS7 PTPN11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ACVR1B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SEPT12 25402006 pred G SOCS7 AKT2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SHROOM2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ECT2 25402006 pred G G G G G G G G G G SOCS7 KIT 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DGKQ 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RGS14 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SLA2 23023127 pred G G G G G G G G G G G G G G G G SOCS7 MTMR4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SPOCK1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SUV39H2 25402006 pred G G G G G G G G G G G G G G SOCS7 PPP1R3F 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NEDD9 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RASGRF2 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 VAV2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SCN2B 23023127 pred G G G G G G G G G G SOCS7 F7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FGFR1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PRKCQ 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PIK3CA 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DLG2 23023127 pred G G G G G G G G SOCS7 MAPK8IP1 23023127 pred G G G G G G G SOCS7 HGF 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GADD45GIP1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DLC1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DRD1 23023127 pred SOCS7 DOK4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PIK3R3 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 LCP2 23023127 pred G G G G G G G G G G G G G G G G G SOCS7 VTN 23023127 pred SOCS7 WDTC1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FGFR4 25402006 pred G G G G G G G G G G G G G SOCS7 VCPIP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FOXH1 25402006 pred G G G G G G G G G G G G G G G SOCS7 TNN 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CBFA2T3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DLX4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 TIAM1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 OBSCN 23023127 pred G G G G G G G G G G G G G SOCS7 IPCEF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G SOCS7 NGEF 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS7 RGL4 16082366 pred G G G G SOCS7 ALK 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CX3CL1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTPRU 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PDIA2 25402006 pred G G G G G G G G G G G G G G SOCS7 PIAS3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PAK2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RAPGEF3 16082366 pred G G G G G G G G G G G G G G G G G G G G G SOCS7 RCHY1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SH3GLB2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 AR 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MIA3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G WASL SOCS7 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 INSRR 25402006 pred G G G SOCS7 BAIAP2 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS7 AKAP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SRC 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTK2B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PAK3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 AHSG 23023127 pred G G SOCS7 PLEKHA1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DAXX 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NCKIPSD 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GHR 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SH2D3C 23023127, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ABL2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 KLK7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTPRF 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PRSS8 23023127 pred G G G G G G G G G G G G G G G G G G G SOCS7 TXK 25402006 pred G G G G G G G G SOCS7 IGFBP1 23023127 pred G G G G G G SOCS7 NOV 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ARHGEF7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SH2D1A 23023127 pred G G SOCS7 SOCS5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GLTSCR1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 BAZ2A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PSD3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 AMPH 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PLAT 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RGL2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MAPK1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CELSR3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PLCG2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ACVR2A 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 STAT4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DGKD 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CISH 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PTPRN 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 TNK2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 KHDRBS1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IRF1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PICK1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NLK 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 BRD4 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 STAT1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DLGAP3 25402006 pred G G G G G SOCS7 MATK 23023127 pred G G G G G G G G G G SOCS7 STAP1 23023127 pred G G G G G G G SH2B2 SOCS7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 APBA2 23023127 pred G G G G G G G G G SOCS7 RNF11 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 AP3S1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 EP300 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SPEN 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RUSC2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ZNF106 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CNKSR1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RAPGEF1 25402006, 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 F10 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS7 EPCAM 23023127 pred G G G G G G G G G G G G G G G G G G SOCS7 PDGFRB 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 EPHA7 23023127 pred G G G G G G G G G G G G G G G SOCS7 RUSC1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PHF20L1 SOCS7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RASGEF1C 16082366 pred G G G G G G SOCS7 EPHB6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RASGRP2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G APBB1 SOCS7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SOCS4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MINK1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PRSS2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 INPP5D 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 AHI1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SOS2 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SOS1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 KMT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FABP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ADRB1 23023127 pred G G G G G G G G G G G G G G G G SOCS7 GRB10 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DOK6 23023127 pred G G G G G G G G G G G SOCS7 BLNK 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 OVCH1 23023127 pred SOCS7 CBL 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CNKSR2 23023127 pred G G G G G G G G G G G G G G SOCS7 SOCS3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MLK4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 MYLK 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NELL2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TULP1 SOCS7 25402006 pred G G G G G G SOCS7 BMPER 23023127 pred G SOCS7 FOXO1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IGFBP7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PEBP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NCK2 25402006, 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RET 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GRAP 25402006 pred G G G G G G SOCS7 SAFB2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SYK 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DZIP3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 VAV3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NTRK1 23023127 pred G SOCS7 PRSS3 23023127 pred SOCS7 PRKCZ 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 BRMS1L 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 AKT1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ZAP70 23023127 pred G G G G G G G G G G G SOCS7 FYB 25402006 pred G G G G G G G G G G G G G G G G G G G G G G SOCS7 RIN3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 THY1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FARP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 APBA1 23023127 pred G G G G G G G G G G G G G G G G G G G G G SOCS7 KLK14 23023127 pred SOCS7 ERBB4 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 KLK6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GRB14 23023127 pred G G G G G G G G G G G G SOCS7 SOCS1 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS7 RGL1 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NPTN 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ACR 23023127 pred G G G G G G G G G G G G SOCS7 KLK5 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PIM1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SH2D6 23023127 pred G G G G G G G G G G G G G G SOCS7 PRKCG 23023127 pred G G G G G G G G G G G G G G G G G G G G G G SOCS7 ERBB2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS2 SOCS7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FRS3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 STAR 23023127 pred G G G G SOCS7 SHC4 23023127 pred G G G G G G G G G SOCS7 PRSS1 23023127 pred G G G G G G G G SOCS7 ARNT2 23023127 pred G G G G G G G G G G G G G G G G G G G G SOCS7 JAK3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 FLT3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G SOCS7 ABI2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GRAP2 25402006, 23023127 pred SOCS7 STAT2 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 IKZF1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 DLGAP2 25402006 pred G G G G G G G G G G G G G G G G SOCS7 SH3KBP1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SH3PXD2B SOCS7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SHC1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RALGPS2 16082366 pred G G G G G G G G G G G G G G G G G SOCS7 RELA 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PPP1R13B 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NDUFA13 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PDPK1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 JAK1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SORBS1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SEMA7A 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 PRKCD 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 RASA1 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ERBB3 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ACVR1C 23023127 pred G G G G G G G G G G G G G G G G G G G G G SOCS7 EPHA5 23023127 pred G G G G G G G G G G G G G G G G G G SOCS7 SOCS6 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 SHANK3 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 NTRK2 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G RNF103 SOCS7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 CREBBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 GRB7 23023127 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G SOCS7 ISLR2 23023127 pred G G G G G G G G G G SOCS7 BCAR3 16082366 pred G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P42229 O14512 affinity chromatography technology 15677474 physical association X 2 O14512 two hybrid 15242778 direct interaction X 2 O14512 Q93034 affinity chromatography technology 21145461 physical association X 2 O14512 two hybrid 15677474 direct interaction X 2 O14512 affinity chromatography technology 15677474 physical association X 2 O14512 affinity chromatography technology 17803907 physical association X 2 O14512 P16333 two hybrid 9344857 direct interaction X 2 O14512 P16333 pull down 9344857 direct interaction X 2 O14512 P62993-2 in vitro 9344857 - X 2 O14512 P00533 in vitro 9344857 - X 2 O14512 P27986 in vitro 12052866 - X 2 O14512 P19174 in vitro 9344857 - X 2 O14512 P19174 in vitro 9344857 - X 2 O14512 P00533 in vitro 9344857 - X 2 O14512 P62993-2 in vitro 9344857 - X 2 O14512 P27986 in vitro 12052866 - X 2 O60504-2 O14512 in vivo 15242778 - X 2 O60504-2 O14512 two hybrid 15242778 - X 2 O60504-2 O14512 two hybrid 15242778 - X 2 O60504-2 O14512 in vivo 15242778 - X 2 Q71U36 O14512 in vitro 12052866 - X 2 Q71U36 O14512 in vitro 12052866 - X 2 P68371 O14512 in vivo 12052866 - X 2 P68371 O14512 in vivo 12052866 - X 2 O14512 in vitro 12052866 - X 2 O14512 in vitro 12052866 - X 2 O14512 P16333 two hybrid 9344857 - X 2 O14512 P16333 in vitro 9344857 - X 2 O14512 in vitro 12052866 - X 2 O14512 O14654 in vitro 12052866 - X 2 O14512 O14654 in vivo 12052866 - X 2 O14512 O14654 in vivo 12052866 - X 2 O14512 O14654 in vitro 12052866 - X 2 O14512 P16333 in vitro 9344857 - X 2 O14512 P16333 two hybrid 9344857 - X 2 O14512 in vitro 12052866 - X 2 O14512 anti bait coimmunoprecipitation 17803907 association C 3 O14512 anti bait coimmunoprecipitation 17803907 association C 3 O14512 Q8IZP0 array technology 20598684 direct interaction X 2 O14512 Q8IZP0 array technology 20598684 direct interaction X 2 O14512 O60504 anti tag coimmunoprecipitation 15242778 physical association X 2 O14512 O60504 two hybrid 15242778 physical association X 2 O14512 O60504 fluorescence microscopy 15242778 colocalization X 2 O14512 Q14141 anti bait coimmunoprecipitation 17803907 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B SOCS7 ABI1 MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology)|MI:0008(array technology) 20598684 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint) UniProt_185980|UniProt_109601|UniProt_109626|UniProt_173628|MINT_77047|UniProt_173603|MINT_46317|UniProt_185955|MINT_77022|MINT_46342 prey|prey|prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait|bait|bait SOCS7 TUBB4B MI:0492(in vitro) 12052866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25634 - - SOCS7 TUBA1A MI:0492(in vitro) 12052866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25610 - - SOCS7 NCK1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 9344857 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_110384|BIOGRID_110385|HPRD_7150 prey|bait|- bait|prey|- PIK3R2 SOCS7 MI:0492(in vitro) 12052866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25675 - - SOCS7 IRS2 MI:0492(in vitro) 12052866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25414 - - SOCS7 GRB2 MI:0492(in vitro) 9344857 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_4682 - - SOCS7 SORBS3 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0007(anti tag coimmunoprecipitation)|MI:0493(in vivo) 15242778 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|- MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(biogrid)|(intact)|MI:0468(hprd) MINT_30917|MINT_59390|MINT_30924|MINT_59383|UniProt_79557|MINT_59388|UniProt_79556|MINT_30922|BIOGRID_211466|UniProt_79555|HPRD_30864 bait|unspecified role|unspecified role|bait|unspecified role|bait|bait|bait|bait|bait|- null|unspecified role|unspecified role|null|unspecified role|prey|null|prey|prey|prey|- SOCS7 PIK3R1 MI:0492(in vitro) 12052866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25006 - - SOCS7 STAT3 MI:0018(two hybrid)|MI:0018(two hybrid) 15677474 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_211739|BIOGRID_211737 bait|bait prey|prey SOCS7 PLCG1 MI:0492(in vitro) 9344857 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_901 - - SOCS7 CUL5 MI:0004(affinity chromatography technology) 21145461 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_203658 prey bait SOCS7 EGFR MI:0492(in vitro) 9344857 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_31355 - - SOCS7 SEPT6 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17803907 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid) UniProt_92991|UniProt_92988|UniProt_92990|BIOGRID_213625 null|prey|null|prey bait|bait|bait|bait SOCS7 IRS4 MI:0492(in vitro) 12052866 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_25702 - - SOCS7 STAT5A MI:0018(two hybrid) 15677474 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_211738 bait prey

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8IZP0 O14512 ABI1 SOCS7 0.309 20598684 Q9UJY1 O14512 HSPB8 SOCS7 0.236 unassigned1304 Q8NHY3 O14512 GAS2L2 SOCS7 0.236 unassigned1304 Q96PV6 O14512 LENG8 SOCS7 0.236 unassigned1304 Q96B26 O14512 EXOSC8 SOCS7 0.236 unassigned1304 Q99750 O14512 MDFI SOCS7 0.236 unassigned1304 O14512 B8A4K4 SOCS7 CYSRT1 {ECO:0000313|ENSEMBL:ENSP00000386453} 0.236 unassigned1304 Q63HR2 O14512 TENC1 SOCS7 0.236 unassigned1304 O14512 J3QRU1 SOCS7 YES1 {ECO:0000313|ENSEMBL:ENSP00000464380} 0.236 unassigned1304 Q6X4W1 O14512 NSMF SOCS7 0.236 unassigned1304 P40763 O14512 STAT3 SOCS7 0.454 15677474 O75553 O14512 DAB1 SOCS7 0.523 24210661 O43639 O14512 NCK2 SOCS7 0.236 unassigned1304 P62993 O14512 GRB2 SOCS7 0.236 unassigned1304 Q8IVT2 O14512 MISP SOCS7 0.236 unassigned1304 O94875 O14512 SORBS2 SOCS7 0.236 unassigned1304 O60504 O14512 SORBS3 SOCS7 0.748 15242778,unassigned1304 Q14141 O14512 SEPT6 SOCS7 0.507 17803907 Q93034 O14512 CUL5 SOCS7 0.309 24210661,21145461 P16333 O14512 NCK1 SOCS7 0.523 9344857 P42229 O14512 STAT5A SOCS7 0.21 15677474

PPI - InWeb_IM Gene A Gene B MI 1 Interaction 1 MI 2 Interaction 2 SOCS7 SORBS3 MI:0045 experimental interaction detection MI:0461 interaction database SOCS7 NCK1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS7 TAF1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS7 STAT3 MI:0045 experimental interaction detection MI:0461,MI:1106 interaction database,pathways database SOCS7 STAT5A MI:0045 experimental interaction detection MI:0461 interaction database SOCS7 LEPR MI:0362 inference MI:0461 interaction database SOCS7 SEPT6 MI:0045 experimental interaction detection MI:0461 interaction database SOCS7 SEPT2 MI:0362 inference MI:0461 interaction database SOCS7 TCEB1 MI:0362 inference MI:0461 interaction database SOCS7 TCEB2 MI:0362 inference MI:0461 interaction database SOCS7 ABI1 MI:0045 experimental interaction detection MI:0461 interaction database SOCS7 CUL5 MI:0045 experimental interaction detection MI:0461 interaction database