Mutation - TCGA Type Chromosome Start Position End Position Strand Variant Classification Variant Type Reference Allele Tumor_seq Allele 1 Tumor_seq Allele 2 Tumor Sample Barcode Matched Norm Sample Barcode Genome Change cDNA Change Codon Change Protein Change ACC 14 94510351 94510353 + In_Frame_Del DEL CTT CTT - TCGA-P6-A5OH-01A-11D-A30A-10 TCGA-P6-A5OH-11A-01D-A30A-10 g.chr14:94510351_94510353delCTT c.253_255delCTT c.(253-255)cttdel p.L86del BLCA 14 94512231 94512231 + Missense_Mutation SNP C C T TCGA-DK-A1AC-01A-11D-A13W-08 TCGA-DK-A1AC-10A-01D-A13W-08 g.chr14:94512231C>T c.668C>T c.(667-669)tCc>tTc p.S223F BRCA 14 94505335 94505335 + Silent SNP C C T TCGA-AO-A03M-01B-11D-A10M-09 TCGA-AO-A03M-10A-01D-A10M-09 g.chr14:94505335C>T c.126C>T c.(124-126)atC>atT p.I42I COAD 14 94511022 94511022 + Missense_Mutation SNP G G A TCGA-D5-6930-01A-11D-1924-10 TCGA-D5-6930-10A-01D-1924-10 g.chr14:94511022G>A c.394G>A c.(394-396)Gtg>Atg p.V132M COAD 14 94512078 94512078 + Missense_Mutation SNP C C T TCGA-D5-6930-01A-11D-1924-10 TCGA-D5-6930-10A-01D-1924-10 g.chr14:94512078C>T c.515C>T c.(514-516)gCc>gTc p.A172V COADREAD 14 94505427 94505427 + Splice_Site SNP A A C TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr14:94505427A>C c.218A>C c.(217-219)aAg>aCg p.K73T COADREAD 14 94511022 94511022 + Missense_Mutation SNP G G A TCGA-D5-6930-01A-11D-1924-10 TCGA-D5-6930-10A-01D-1924-10 g.chr14:94511022G>A c.394G>A c.(394-396)Gtg>Atg p.V132M COADREAD 14 94512078 94512078 + Missense_Mutation SNP C C T TCGA-D5-6930-01A-11D-1924-10 TCGA-D5-6930-10A-01D-1924-10 g.chr14:94512078C>T c.515C>T c.(514-516)gCc>gTc p.A172V ESCA 14 94503806 94503806 + Nonsense_Mutation SNP C C A TCGA-L5-A8NV-01A-11D-A37C-09 TCGA-L5-A8NV-11A-11D-A37F-09 g.chr14:94503806C>A c.84C>A c.(82-84)taC>taA p.Y28* GBMLGG 14 94503790 94503790 + Missense_Mutation SNP C C T TCGA-TM-A84H-01A-11D-A36O-08 TCGA-TM-A84H-10A-01D-A367-08 g.chr14:94503790C>T c.68C>T c.(67-69)cCt>cTt p.P23L HNSC 14 94510931 94510931 + Splice_Site SNP G G A TCGA-CN-6024-01A-11D-1683-08 TCGA-CN-6024-10A-01D-1683-08 g.chr14:94510931G>A c.e5-1 HNSC 14 94511037 94511037 + Missense_Mutation SNP C C G TCGA-CR-6484-01A-11D-1870-08 TCGA-CR-6484-10A-01D-1870-08 g.chr14:94511037C>G c.409C>G c.(409-411)Ctg>Gtg p.L137V HNSC 14 94511065 94511065 + Missense_Mutation SNP G G A TCGA-CV-7102-01A-11D-2012-08 TCGA-CV-7102-10A-01D-2013-08 g.chr14:94511065G>A c.437G>A c.(436-438)cGa>cAa p.R146Q KIPAN 14 94511094 94511094 + Missense_Mutation SNP G G A TCGA-B0-5713-01A-11D-1669-08 TCGA-B0-5713-11A-01D-1669-08 g.chr14:94511094G>A c.466G>A c.(466-468)Gag>Aag p.E156K KIRC 14 94511094 94511094 + Missense_Mutation SNP G G A TCGA-B0-5713-01A-11D-1669-08 TCGA-B0-5713-11A-01D-1669-08 g.chr14:94511094G>A c.466G>A c.(466-468)Gag>Aag p.E156K LGG 14 94503790 94503790 + Missense_Mutation SNP C C T TCGA-TM-A84H-01A-11D-A36O-08 TCGA-TM-A84H-10A-01D-A367-08 g.chr14:94503790C>T c.68C>T c.(67-69)cCt>cTt p.P23L LUAD 14 94510400 94510400 + Splice_Site SNP C C T TCGA-64-5778-01A-01D-1625-08 TCGA-64-5778-10A-01D-1625-08 g.chr14:94510400C>T c.302C>T c.(301-303)gCt>gTt p.A101V OV 14 94511024 94511024 + Silent SNP G G T TCGA-24-1426-01A-01W-0549-09 TCGA-24-1426-10A-01W-0549-09 g.chr14:94511024G>T c.396G>T c.(394-396)gtG>gtT p.V132V READ 14 94505427 94505427 + Splice_Site SNP A A C TCGA-AG-A002-01A-01W-A00K-09 TCGA-AG-A002-10A-01W-A00K-09 g.chr14:94505427A>C c.218A>C c.(217-219)aAg>aCg p.K73T SKCM 14 94510998 94510998 + Missense_Mutation SNP G G A TCGA-FW-A3R5-06A-11D-A23B-08 TCGA-FW-A3R5-10A-01D-A23B-08 g.chr14:94510998G>A c.370G>A c.(370-372)Gac>Aac p.D124N

Mutation - COSMIC Sample Name Mutation ID Mutation CDS Mutation AA Mutation Description Mutation Genome Position Mutation Strand SH-1537 COSM5018536 c.218+10G>A p.? Unknown 14:94039091-94039091 + TCGA-AG-A002-01 COSM262699 c.218A>C p.K73T Substitution - Missense 14:94039081-94039081 + 587220 COSM1218997 c.197G>T p.G66V Substitution - Missense 14:94039060-94039060 + TCGA-B0-5713-01 COSM470374 c.466G>A p.E156K Substitution - Missense 14:94044748-94044748 + YUROL COSM5382926 c.180C>T p.Y60Y Substitution - coding silent 14:94039043-94039043 + TCGA-DK-A1AC-01 COSM1300923 c.668C>T p.S223F Substitution - Missense 14:94045885-94045885 + TCGA-G4-6297-01 COSM3690261 c.38G>A p.C13Y Substitution - Missense 14:94037414-94037414 + S01733 COSM4386794 c.20A>G p.N7S Substitution - Missense 14:94037396-94037396 + T2197 COSM4710564 c.418T>A p.S140T Substitution - Missense 14:94044700-94044700 + TCGA-BR-4201-01 COSM4053199 c.343G>A p.V115M Substitution - Missense 14:94044625-94044625 + TCGA-AO-A03M-01 COSM3815586 c.126C>T p.I42I Substitution - coding silent 14:94038989-94038989 + TCGA-HU-A4H8-01 COSM4053198 c.231C>T p.R77R Substitution - coding silent 14:94043983-94043983 + Pat_53_B COSM5848778 c.229C>T p.R77C Substitution - Missense 14:94043981-94043981 + BD119T COSM5520910 c.451C>T p.R151W Substitution - Missense 14:94044733-94044733 + SNUH_G10_S1 COSM3678008 c.659A>G p.Y220C Substitution - Missense 14:94045876-94045876 + TCGA-BS-A0UV-01 COSM959100 c.624C>A p.F208L Substitution - Missense 14:94045841-94045841 + SJHGG009_A COSM4969058 c.646G>T p.V216F Substitution - Missense 14:94045863-94045863 + PT35 COSM5913603 c.89G>A p.R30K Substitution - Missense 14:94037465-94037465 + TCGA-EJ-7125-01 COSM3671989 c.120C>A p.T40T Substitution - coding silent 14:94038983-94038983 + TCGA-D5-6930-01 COSM1371744 c.515C>T p.A172V Substitution - Missense 14:94045732-94045732 + TCGA-24-1426-01 COSM118877 c.396G>T p.V132V Substitution - coding silent 14:94044678-94044678 + S0029 COSM5882541 c.100G>A p.E34K Substitution - Missense 14:94038963-94038963 + TCGA-FW-A3R5-06 COSM3886580 c.370G>A p.D124N Substitution - Missense 14:94044652-94044652 + PT48 COSM5933307 c.176C>T p.S59F Substitution - Missense 14:94039039-94039039 + CHEWS029 COSM4578077 c.405G>A p.L135L Substitution - coding silent 14:94044687-94044687 + GB23 COSM1744015 c.636C>T p.A212A Substitution - coding silent 14:94045853-94045853 + BK0004 COSM4185534 c.463G>A p.D155N Substitution - Missense 14:94044745-94044745 + 1115244 COSM5567403 c.420G>A p.S140S Substitution - coding silent 14:94044702-94044702 + TCGA-AP-A051-01 COSM959099 c.281A>G p.K94R Substitution - Missense 14:94044033-94044033 + Pat_26_A COSM5848777 c.86G>A p.R29Q Substitution - Missense 14:94037462-94037462 +

Mutation - CGAP UNIGENE CYTOBAND OMIM SNP Hs.278815 14q32.12 608338

Mutation - IntOGen Mutated from(ref) Mutated to(alt) Consequence Type AA Mutation CDS Mutation Chr Pos Cancer C A 3-UTRSNV . c.702+803C>A 14 94513068 HC C G Missense p.L137V c.409C>G 14 94511037 HNSC C T Missense p.A101V c.302C>T 14 94510400 LUAD G A Missense p.E156K c.466G>A 14 94511094 RCCC G A Missense p.R146Q c.437G>A 14 94511065 HNSC G A Missense p.R43H c.128G>A 14 94505337 CM G A Missense p.V115M c.343G>A 14 94510971 STAD G A SpliceAcceptorSNV . c.304-1G>A 14 94510931 HNSC G T Synonymous p.V132V c.396G>T 14 94511024 OV T C 3-UTRSNV . c.702+1216T>C 14 94513481 HC