PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus E2F4 RYBP 12411495 biogrid exp G G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP G G ATF7IP RYBP 26186194 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G HSPB1 RYBP 25277244 biogrid,intact exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G WDR5 RYBP 26186194,22325352 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PCGF3 RYBP 26186194,22325352 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CSNK2A2 RYBP 26186194,23455922,22325352 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NOS1AP RYBP 25814554 biogrid,intact exp G G G P G P P P E2F2 RYBP 12411495 hprd,biogrid,i2d exp GP G G G G G G G G P P G G G G GP G P G G G GP GP EED RYBP 24457600 innatedb,biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP G G GP GP G GP GP G RYBP AUTS2 26186194,25519132 biogrid exp G G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RYBP GABPB2 11953439 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM RYBP 17070805 mint,intact exp GP G G G G G G GP P G G P G P G P GP G P P G GP GP MAPK8IP2 RYBP 25814554 biogrid,intact exp G G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G HERC2 RYBP 26186194 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G BCORL1 RYBP 26186194,22325352 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP FBRSL1 26186194,22325352 biogrid exp G G G G G G G G G G GP G G G G GP G G G G G G G G GP G GP GP G RYBP ZFP42 21530438 biogrid exp P P P P P P P P P P P RYBP PCGF6 26186194,22325352 biogrid exp G G G G G G G G G G GP G G G G G G G G G G G G G G G G G G E2F3 RYBP 12411495 hprd,biogrid,i2d,bci exp G G G G G G G G G G G G G G G G G G G G G G G G SOCS2 RYBP 20543098 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP L3MBTL2 26186194,22325352 biogrid exp GP G G G G G G G G G G G G G G GP G G G G G GP G G GP G G G G PCGF5 RYBP 26186194,22325352 biogrid exp GP G G G G G G G G G GP G G G G GP G G G G G G G GP GP G GP GP G ELAVL1 RYBP 19322201 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G UBC RYBP 17070805 mint,intact exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP MORC4 26186194 biogrid exp GP G G G G G G G G G G G G G G G G G GP G G G G G G GP G RYBP FBRS 26186194,22325352 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CRK RYBP 25814554 biogrid,intact exp GP G G G G G G G G G GP G G G G GP G G GP G GP GP G GP GP G GP G G CBX3 RYBP 22325352 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G MGA RYBP 26186194,22325352 biogrid exp GP G G G G G G G G G GP G GP G G GP G G GP G GP G G GP GP G GP GP G PCGF2 RYBP 26186194,22325352, 25402006 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CSNK2A1 RYBP 26186194,22325352, 25402006 biogrid exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP USP7 26186194,22325352, 25402006 biogrid exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP CASP10 11395500, 25402006, 21836163 hprd,biogrid,bci exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G ABL1 RYBP 8943360, 25402006 biogrid exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G BMI1 RYBP 24457600,26186194,20601937,22325352, 25402006, 21836163 innatedb,biogrid,intact exp, pred P P P P P P P P P P P RYBP PCGF1 16943429,26186194,22325352, 21836163 biogrid,intact exp, pred P G G G G G G P GP G P G G GP G GP GP G GP GP GP GP G BCOR RYBP 16943429,26186194,22325352, 21836163 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G RING1 RYBP 25416956,16943429,10369680,16189514,26186194,22325352,17070805, 25402006 hprd,biogrid,mint,intact exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G TFCP2 RYBP 25402006 bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CBX2 RYBP 10369680, 25402006, 21836163 hprd,biogrid exp, pred P G P G P G P P GP G G TP53 RYBP 19098711, 25402006 biogrid,mint,intact exp, pred G G G G G G G G G G G G G G G GP G G G G GP G G G GP G G GP G YY1 RYBP 10369680,11953439, 25402006, 21836163 hprd,biogrid,bci exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G E2F6 RYBP 11171983,26186194,12411495,22325352, 25402006, 21836163 hprd,biogrid,mint,intact,bci exp, pred G G G G G G G G G G G G G G G G G G G G G G G TFDP1 RYBP 26186194,22325352, 25402006 biogrid exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G FADD RYBP 11395500, 21836163 hprd,biogrid,bci exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP G G GP GP G GP GP G SKP1 RYBP 22325352, 21836163 biogrid exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RYBP RNF2 24457600,26186194,20696397,10369680,16943429,26496610,17070805,22325352, 25402006, 21836163 innatedb,hprd,biogrid,intact,dip,bci exp, pred G P P P P P P P P P CASP8 RYBP 11395500, 25402006 hprd,bci exp, pred GP G G G G G GP G GP G G GP G P G GP GP G P GP G GP GP G CSNK2B RYBP 26186194,22325352, 25402006 biogrid exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G MDM2 RYBP 19098711, 25402006 biogrid,mint,intact exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G GABPB1 RYBP 11953439, 21836163 hprd,biogrid,bci exp, pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP KDM2B 26186194,23395003,22325352, 21836163 biogrid exp, pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G RYBP COPS5 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G POU5F1 RYBP 25402006 pred P P P P P P P P P P P ABCB1 RYBP 25402006 pred G G G G G G G G G G GP G G G G GP G G G G G G G G GP G G G G TERF1 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CDKN1A RYBP 25402006 pred GP G G G G G G G G G G G GP G G GP G G G G GP G G G GP G G GP G ARRB1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RYBP ZBTB10 21836163 pred GP G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP RB1CC1 25402006 pred G G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RAD51 RYBP 25402006 pred P G G G G P G P GP G G GP GP P P GP GP GP NFYA RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CSNK1D RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP GNL3 25402006 pred P G P P G GP GP GP GP P P P P TAF9 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G HDAC1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G IL33 RYBP 25402006 pred GP G G G G G G G G G G G G P G G G P G G GP G CBX4 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G CSNK1A1 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G GP G G G G G G G G G G RYBP EPC1 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2A RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G NFYB RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G MDM4 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP ZMIZ1 25402006 pred GP G G G G G G G G G GP G G G G G G G G G G G G G G G GP GP G PRKDC RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G MYBL2 RYBP 25402006 pred P G G P P G GP GP G P P P GP G GP GP FOXO4 RYBP 25402006 pred G G G G G G G G G G G G G GP G G GP G GP G G GP GP G G GP G RYBP JMY 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G E2F1 RYBP 25402006 pred P G G G G G G G G G GP G GP G GP G G GP G P P G P GP GP GP G SUMO1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP SIRT1 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G NUMB RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G ESR1 RYBP 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G UBE2I RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G ALPI RYBP 21836163 pred GP P GP CASP3 RYBP 25402006 pred GP G G G G G G G G G G GP G G GP G G GP G GP G G G GP G GP GP G CFLAR RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP MTBP 25402006 pred P P P P P P P P XPO1 RYBP 25402006, 16082366 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RRM2B RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G PPM1D RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP TP63 25402006 pred GP G G G G G G G G G G G G G G G G G G GP GP G G G G G ATM RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G EP300 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CTBP1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G BRCA1 RYBP 25402006 pred P G G P P GP P P P P P P GP PIAS1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G TNFRSF10A RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G G G GP G G G GP G GP GP G UBE2K RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RPL23 RYBP 25402006 pred P P P P P P P P P P P S100A1 RYBP 25402006 pred GP G G G G G G G GP GP G G GP G G GP G GP G G GP GP GP GP G RYBP DAXX 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RB1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP WASF1 25402006 pred GP G G G G G G G G G GP G P G G GP G G P G GP GP G P GP G GP GP G RYBP ING4 25402006 pred GP G G G G G G G G G GP G GP G G GP G G P G GP GP G GP GP G GP GP G RYBP AATF 25402006, 21836163 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TFDP2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP HIPK2 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G THRB RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G UBE2N RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G PIAS4 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G RYBP CREBBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP YTHDC1 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP SIN3A 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G UBE2D2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G G G G GP G GP GP G GP G G GP GP G ELL RYBP 25402006 pred GP G G G P P P G G G GP G G P P GP G RYBP KAT8 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TBP RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G PTK2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP ING1 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G TP73 RYBP 25402006 pred G G G G G NCL RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G SMAD2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G SET RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G SP1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CBX7 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G PSME3 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G MTA1 RYBP 25402006 pred G G G G G G G G G G GP G GP G G GP G G GP G GP G G G GP G GP GP G RYBP TSG101 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G NR4A1 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TP53BP2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP FBXW11 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G GTF2H1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G NPM1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G ERCC6 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G TNFSF10 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP P G CDK1 RYBP 25402006 pred GP G G G G P P GP G GP G GP P GP G GP GP RYBP HDAC2 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CHEK2 RYBP 25402006 pred GP G G G G G P P GP G GP G P G P GP GP G HIPK1 RYBP 25402006 pred G G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G S100B RYBP 25402006 pred G G G G G G P GP G G G G P G GP G P G GP P SOS2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G IRF2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G HIF1A RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP G G G GP G GP GP G POU5F1B RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G RYBP CBX8 25402006 pred P P P P P P P P P P P TFE3 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G E4F1 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G PARP1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP SMARCC1 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G HIST2H2AC RYBP 25402006 pred P P P P P P P P P P P YWHAZ RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G S100A4 RYBP 25402006 pred G G G G G G G G G G G G GP G G G G G G G GP G G G G G G G G S100A2 RYBP 25402006 pred GP G G G G G GP G G G G G G G G G PHB RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G BTK RYBP 25402006 pred G G G G G GP G G G G G NR3C1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G EZH2 RYBP 25402006 pred GP G G G P G G GP G P P GP G GP GP ERCC3 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G AR RYBP 25402006 pred GP G G G G G G G G G G G G G G G G G G G G G G G GP G ABL2 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CTCF RYBP 16082366 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CEBPB RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G BID RYBP 25402006 pred G G G G G G G G G G G GP G G GP G G GP G G GP G GP GP G GP PML RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G JUN RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G G G GP G G G GP G GP G G PPP1CC RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G PSMD10 RYBP 25402006 pred GP G G G G G G G G G G G GP G G GP G G GP G GP GP G G GP G GP GP G PIAS2 RYBP 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G G CTNNB1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RYBP KAT2B 25402006 pred G G G G G G G G G G G G G G G G G G G G G G G G G G G G ABI1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CREB1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G FAS RYBP 25402006 pred GP G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RYBP KAT5 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G PLK1 RYBP 25402006 pred P G G G G G G P P G GP G G GP G GP P G GP GP P GP CHD3 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G CDK7 RYBP 25402006 pred GP G G G G G G G G G GP GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP TOPORS 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G RYBP IFT57 21836163 pred GP G G G G G G G G G GP GP G G GP G G GP G GP GP G GP GP G GP GP G CDK3 RYBP 25402006 pred P P P P P P P P P P BRD2 RYBP 25402006 pred G G G G G G G G G G GP G GP G G GP G G GP G GP G G GP GP G GP GP G CDK9 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G SMARCA4 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G ATF3 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G G GP G GP GP G RYBP RCHY1 25402006 pred G G G G G G G G G G GP G GP G G GP G G GP G G G G G GP G GP G G FHL1 RYBP 25402006 pred G G G G G G G G G G GP G GP G G G G G GP G GP G G GP G G G G G RPL11 RYBP 25402006 pred GP G G G G G G G G G G G GP G G GP G G GP G GP GP G GP GP G GP GP G MED1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G GP G G GP G GP GP G GP GP G GP GP G UBE2D1 RYBP 25402006 pred GP G G G G G G G G G GP G GP G G G G G GP G GP GP G GP G G GP GP G SFN RYBP 25402006 pred GP G G G G G G G G G G G GP G G G G G G G G GP G G G G G G G HTT RYBP 25402006 pred GP G G G G G G G G G P G P G G GP G G P G GP GP G G GP G GP GP

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8N488 affinity chromatography technology 10369680 physical association X 2 Q8N488 pull down 10369680 direct interaction X 2 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8N488 A0A024R1V6 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q86SE9 affinity chromatography technology 22325352 physical association X 2 Q8N488 A0A024R1V6 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q86SE9 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q6W2J9-4 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q8NHM5 affinity chromatography technology 22325352 physical association X 2 Q8N488 A0A024R1V6 affinity chromatography technology 22325352 physical association X 2 Q8N488 unspecified method 20467438 direct interaction X 2 Q8N488 Q8NHM5 affinity chromatography technology 23395003 physical association X 2 Q8N488 E9PJK2 affinity chromatography technology 24457600 physical association X 2 Q8N488 Q59FK4 two hybrid 8943360 direct interaction X 2 Q8N488 Q59FK4 far western blotting 8943360 direct interaction X 2 Q8N488 Q59FK4 pull down 8943360 direct interaction X 2 Q8N488 Q6W2J9-4 affinity chromatography technology 16943429 physical association X 2 N0E4C7 Q8N488 affinity chromatography technology 22325352 physical association X 2 A0A024RDY4 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8N488 affinity chromatography technology 22325352 physical association X 2 P68400-2 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q00987 Q8N488 affinity chromatography technology 19098711 physical association X 2 Q00987 Q8N488 affinity chromatography technology 19098711 physical association X 2 Q00987 Q8N488 pull down 19098711 direct interaction X 2 Q00987 Q8N488 pull down 19098711 direct interaction X 2 Q14209 Q8N488 two hybrid 12411495 direct interaction X 2 Q14209 Q8N488 affinity chromatography technology 12411495 physical association X 2 P19784 Q8N488 affinity chromatography technology 22325352 physical association X 2 P19784 Q8N488 affinity chromatography technology 23455922 physical association X 2 Q06587 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q06587 Q8N488 two hybrid 16189514 direct interaction X 2 Q06587 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q06587 Q8N488 two hybrid 25416956 direct interaction X 2 Q06587 Q8N488 two hybrid 10369680 direct interaction X 2 Q06587 Q8N488 affinity chromatography technology 10369680 physical association X 2 Q06587 Q8N488 affinity chromatography technology 10369680 physical association X 2 Q06587 Q8N488 pull down 10369680 direct interaction X 2 Q06587 Q8N488 pull down 16943429 direct interaction X 2 Q16254 Q8N488 two hybrid 12411495 direct interaction X 2 Q9BYE7 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q9BYE7 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q9BYE7 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q99496 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q99496 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q99496 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q99496 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q99496 Q8N488 affinity chromatography technology 24457600 physical association X 2 Q99496 Q8N488 pull down 16943429 direct interaction X 2 P63208 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8N488 two hybrid 11953439 direct interaction X 2 Q8N488 pull down 11953439 direct interaction X 2 Q8N488 affinity chromatography technology 11953439 physical association X 2 Q93009 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q9HAH7 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q13158 Q8N488 affinity chromatography technology 11395500 physical association X 2 A4D177 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q9BSM1 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q9BSM1 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q9BSM1 affinity chromatography technology 22325352 physical association X 2 Q8N488 Q9BSM1 affinity chromatography technology 22325352 physical association X 2 Q8N488 O00716 two hybrid 12411495 direct interaction X 2 Q8N488 O00716 affinity chromatography technology 12411495 physical association X 2 Q8N488 Q92851-7 affinity chromatography technology 11395500 physical association X 2 Q8N488 Q92851-7 affinity chromatography technology 11395500 physical association X 2 Q8N488 P04637-7 affinity chromatography technology 19098711 physical association X 2 Q8N488 Q9BSM1 affinity chromatography technology 16943429 physical association X 2 Q8N488 A0A024RBD2 two hybrid 20543098 direct interaction X 2 Q96MM3 Q8N488 two hybrid 21530438 direct interaction X 2 Q969R5 Q8N488 affinity chromatography technology 22325352 physical association X 2 P0CG48 Q8N488 affinity chromatography technology 21963094 physical association X 2 P0CG48 Q8N488 affinity chromatography technology 23000965 physical association X 2 P0CG48 Q8N488 affinity chromatography technology 21139048 physical association X 2 P0CG48 Q8N488 affinity chromatography technology 21890473 physical association X 2 P0CG48 Q8N488 affinity chromatography technology 21906983 physical association X 2 Q3KNV8 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q3KNV8 Q8N488 affinity chromatography technology 22325352 physical association X 2 O75461 Q8N488 affinity chromatography technology 22325352 physical association X 2 Q8TAK5 Q8N488 two hybrid 11953439 direct interaction X 2 Q8TAK5 Q8N488 pull down 11953439 direct interaction X 2 O75461 Q8N488 two hybrid 11171983 direct interaction X 2 O75461 Q8N488 pull down 11171983 direct interaction X 2 O75461 Q8N488 pull down 11171983 direct interaction X 2 O75461 Q8N488 affinity chromatography technology 11171983 physical association X 2 O75461 Q8N488 affinity chromatography technology 11171983 physical association X 2 O75461 Q8N488 affinity chromatography technology 12411495 physical association X 2 P25490 Q8N488 two hybrid 11953439 direct interaction X 2 P25490 Q8N488 affinity chromatography technology 11953439 physical association X 2 P25490 Q8N488 affinity chromatography technology 10369680 physical association X 2 P25490 Q8N488 pull down 10369680 direct interaction X 2 P61964 Q8N488 affinity chromatography technology 22325352 physical association X 2 P35226 Q8N488 affinity chromatography technology 22325352 physical association X 2 P35226 Q8N488 affinity chromatography technology 22325352 physical association X 2 P35226 Q8N488 affinity chromatography technology 22325352 physical association X 2 P35226 Q8N488 affinity chromatography technology 22325352 physical association X 2 P35226 Q8N488 affinity chromatography technology 24457600 physical association X 2 Q8N488 coimmunoprecipitation 16943429 association C 8 Q99496 Q8N488 nuclear magnetic resonance 20696397 direct interaction X 2 Q99496 Q8N488 pull down 20696397 direct interaction X 2 Q99496 Q8N488 surface plasmon resonance 20696397 direct interaction X 2 Q99496 Q8N488 ion exchange chromatography 20696397 direct interaction X 2 Q99496 Q8N488 cosedimentation in solution 20696397 direct interaction X 2 Q99496 Q8N488 pull down 20696397 direct interaction X 2 Q99496 Q8N488 x-ray crystallography 20696397 direct interaction X 2 Q14790-5 Q8N488 in vitro 11395500 - X 2 Q14790-5 Q8N488 in vitro 11395500 - X 2 A0A024R5R5 Q8N488 in vivo 11953439 - X 2 A0A024R5R5 Q8N488 in vitro 11953439 - X 2 A0A024R5R5 Q8N488 two hybrid 11953439 - X 2 A0A024R5R5 Q8N488 in vitro 11953439 - X 2 A0A024R5R5 Q8N488 two hybrid 11953439 - X 2 A0A024R5R5 Q8N488 in vivo 11953439 - X 2 Q14781-2 Q8N488 in vivo 10369680 - X 2 Q14781-2 Q8N488 in vitro 10369680 - X 2 Q14781-2 Q8N488 in vitro 10369680 - X 2 Q14781-2 Q8N488 in vivo 10369680 - X 2 Q8N488 in vivo 12411495 - X 2 Q8N488 two hybrid 12411495 - X 2 Q8N488 in vitro 12411495 - X 2 Q8N488 in vitro 12411495 - X 2 Q8N488 in vivo 12411495 - X 2 Q8N488 two hybrid 12411495 - X 2 Q06587 Q8N488 in vivo 10369680 - X 2 Q06587 Q8N488 in vivo 10369680 - X 2 Q99496 Q8N488 in vivo 10369680,17070805 - X 2 Q99496 Q8N488 in vivo 10369680,17070805 - X 2 Q6Q9Z5 Q8N488 in vivo 11171983 - X 2 Q6Q9Z5 Q8N488 two hybrid 11171983 - X 2 Q6Q9Z5 Q8N488 in vitro 11171983 - X 2 Q6Q9Z5 Q8N488 two hybrid 11171983 - X 2 Q6Q9Z5 Q8N488 in vitro 11171983 - X 2 Q6Q9Z5 Q8N488 in vivo 11171983 - X 2 Q92851-3 Q8N488 in vitro 11395500 - X 2 Q92851-3 Q8N488 in vitro 11395500 - X 2 Q13158 Q8N488 in vivo 11395500 - X 2 Q13158 Q8N488 in vivo 11395500 - X 2 Q8N488 O00716 in vitro 12411495 - X 2 Q8N488 O00716 in vivo 12411495 - X 2 Q8N488 O00716 two hybrid 12411495 - X 2 Q8N488 O00716 in vivo 12411495 - X 2 Q8N488 O00716 in vitro 12411495 - X 2 Q8N488 O00716 two hybrid 12411495 - X 2 P25490 Q8N488 in vivo 10369680 - X 2 P25490 Q8N488 in vitro 10369680 - X 2 P25490 Q8N488 in vitro 10369680 - X 2 P25490 Q8N488 in vivo 10369680 - X 2 K7PPA8 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 K7PPA8 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q8N488 P04792 reverse ras recruitment system 25277244 physical association X 2 Q00987 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q00987 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q00987 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q00987 Q8N488 pull down 19098711 physical association X 2 Q00987 Q8N488 pull down 19098711 physical association X 2 Q00987 Q8N488 two hybrid 19098711 physical association X 2 Q00987 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q00987 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q00987 Q8N488 anti tag coimmunoprecipitation 19098711 physical association X 2 Q06587-2 Q8N488 imaging technique 17070805 colocalization X 2 Q06587-2 Q8N488 anti tag coimmunoprecipitation 17070805 physical association X 2 Q06587 Q8N488 two hybrid pooling approach 16189514 physical association X 2 Q06587 Q8N488 pull down 16943429 physical association X 2 Q06587 Q8N488 anti tag coimmunoprecipitation 17070805 physical association X 2 Q06587 Q8N488 mammalian protein protein interaction trap 25416956 physical association X 2 Q06587 Q8N488 two hybrid prey pooling approach 25416956 physical association X 2 Q06587 Q8N488 two hybrid prey pooling approach 25416956 physical association X 2 Q06587 Q8N488 two hybrid array 25416956 physical association X 2 Q06587 Q8N488 two hybrid array 25416956 physical association X 2 Q06587 Q8N488 validated two hybrid 25416956 physical association X 2 Q99496 Q8N488 pull down 16943429 physical association X 2 Q8N488 pull down 16943429 association C 8 Q8N488 tandem affinity purification 23455922 association C 63 Q8N488 anti bait coimmunoprecipitation 19098711 association C 3 Q8N488 anti bait coimmunoprecipitation 19098711 association C 3 Q8N488 tandem affinity purification 20601937 association C 16 P0CG48 Q8N488 anti tag coimmunoprecipitation 17070805 physical association X 2 P0CG48 Q8N488 pull down 17070805 physical association X 2 P0CG48 Q8N488 isothermal titration calorimetry 17070805 direct interaction X 2 O75461 Q8N488 two hybrid 11171983 physical association X 2 A4FTV9 Q8N488 pull down 17070805 physical association X 2 A4FTV9 Q8N488 imaging technique 17070805 colocalization X 2 P31016 Q8N488 peptide array 20467438 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B E2F2 RYBP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 12411495 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_99967|BIOGRID_99954|HPRD_6961 bait|bait|- prey|prey|- MDM2 RYBP MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 19098711 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) MINT_40801|MINT_40799|MINT_40798|MINT_70350|MINT_70351|MINT_70352|MINT_40792|MINT_40791|MINT_40790|UniProt_100168|UniProt_100169|MINT_70347|UniProt_100166|MINT_70349|UniProt_100167|UniProt_100182|MINT_40787|MINT_40789|MINT_70361|MINT_70360|BIOGRID_116220|UniProt_100177|BIOGRID_116223|BIOGRID_116222|BIOGRID_116221|MINT_40800|UniProt_100170|UniProt_100171|MINT_70358|UniProt_100176|MINT_70359|MINT_70348|UniProt_100178|UniProt_100179|MINT_40793|MINT_40788|MINT_70353 bait|prey|prey|bait|bait|prey|prey|bait|bait|prey|prey|prey|prey|bait|bait|bait|prey|bait|bait|prey|bait|bait|bait|prey|prey|prey|prey|bait|prey|prey|prey|bait|bait|prey|prey|bait|prey prey|bait|bait|prey|prey|bait|bait|prey|prey|bait|bait|bait|bait|prey|prey|prey|bait|prey|prey|bait|prey|prey|prey|bait|bait|bait|bait|prey|bait|bait|bait|prey|prey|bait|bait|prey|bait BCOR RYBP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16943429,22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_122927|BIOGRID_191991 bait|prey prey|bait HIST1H2AG RYBP MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry) 17070805 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization) MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint) MINT_51953|UniProt_89222|UniProt_89227|MINT_84414|MINT_51955|MINT_84412 neutral component|prey|neutral component|prey|prey|neutral component neutral component|bait|neutral component|bait|bait|neutral component RYBP KDM2B MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22325352,23395003 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_191993|BIOGRID_280477 bait|prey prey|bait CSNK2B RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191999 prey bait MGA RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191989 prey bait CBX3 RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191985 prey bait TFDP1 RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191987 prey bait SOCS2 RYBP MI:0018(two hybrid) 20543098 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_153778 bait prey RYBP RNF2 MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0493(in vivo)|MI:0004(affinity chromatography technology) 10369680,16943429,22325352,24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0915(physical association) (biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_191975|UniProt_85394|BIOGRID_306573|BIOGRID_191874|BIOGRID_122941|BIOGRID_192027|HPRD_14568|BIOGRID_192024 bait|bait|prey|prey|bait|bait|-|prey prey|prey|bait|bait|prey|prey|-|bait ABL1 RYBP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 8943360 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_112894|BIOGRID_112895|BIOGRID_112896 bait|prey|prey prey|bait|bait CBX2 RYBP MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid) 10369680 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid) HPRD_15333|BIOGRID_92790|BIOGRID_92791 -|prey|prey -|bait|bait E2F4 RYBP MI:0018(two hybrid) 12411495 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_99965 bait prey WDR5 RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191988 prey bait EED RYBP MI:0004(affinity chromatography technology) 24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_306118 bait prey ELAVL1 RYBP MI:0096(pull down) 19322201 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_186436 bait prey UBC RYBP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0004(affinity chromatography technology)|MI:0065(isothermal titration calorimetry)|MI:0004(affinity chromatography technology)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0004(affinity chromatography technology)|MI:0065(isothermal titration calorimetry) 17070805,21139048,21890473,21906983,21963094,23000965 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|MI:0471(mint)|(intact)|(intact)|(biogrid)|MI:0471(mint)|(biogrid)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|MI:0471(mint) BIOGRID_264631|BIOGRID_176866|UniProt_89220|MINT_51949|UniProt_89223|UniProt_89224|BIOGRID_174355|MINT_51947|BIOGRID_167407|MINT_84408|MINT_84406|MINT_84409|BIOGRID_268329|MINT_51950 bait|bait|prey|prey|prey|prey|bait|prey|bait|prey|prey|prey|bait|prey prey|prey|bait|bait|bait|bait|prey|bait|prey|bait|bait|bait|prey|bait RYBP CASP10 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0492(in vitro) 11395500 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_103122|BIOGRID_103121|HPRD_9771 bait|prey|- prey|bait|- RYBP PCGF1 MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16943429,22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) UniProt_85388|BIOGRID_191793|BIOGRID_192029|BIOGRID_122934|BIOGRID_191976|BIOGRID_192035 prey|prey|bait|prey|bait|prey bait|bait|prey|bait|prey|bait RYBP PCGF6 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_191981|BIOGRID_191856|BIOGRID_192041 bait|prey|prey prey|bait|bait SKP1 RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191990 prey bait CASP8 RYBP MI:0492(in vitro) 11395500 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) - MI:0468(hprd) HPRD_9800 - - RYBP USP7 MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191994 bait prey YY1 RYBP MI:0493(in vivo)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 10369680,11953439 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) -|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) MI:0468(hprd)|(biogrid)|(biogrid)|(biogrid)|(biogrid) HPRD_6046|BIOGRID_273847|BIOGRID_273852|BIOGRID_92792|BIOGRID_92793 -|bait|prey|prey|prey -|prey|bait|bait|bait GABPB1 RYBP MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 11953439 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|(biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_273845|BIOGRID_273853|HPRD_15334|BIOGRID_273849 bait|prey|-|bait prey|bait|-|prey RING1 RYBP MI:0018(two hybrid)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0065(isothermal titration calorimetry)|MI:0018(two hybrid)|MI:0096(pull down)|MI:0493(in vivo) 10369680,16189514,16943429,17070805,22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|- (biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(biogrid)|MI:0471(mint)|(biogrid)|(biogrid)|(intact)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0468(hprd) BIOGRID_81237|UniProt_85393|BIOGRID_122940|BIOGRID_192049|BIOGRID_191982|MINT_84411|MINT_84410|BIOGRID_92786|BIOGRID_92785|MINT_69682|BIOGRID_92788|BIOGRID_92787|UniProt_89228|MINT_84413|UniProt_89225|UniProt_89226|MINT_51951|MINT_51952|MINT_51954|MINT_40309|UniProt_154059|HPRD_10234 bait|prey|prey|bait|prey|null|null|bait|bait|bait|prey|prey|null|null|null|null|null|null|null|bait|unspecified role|- prey|bait|bait|prey|bait|bait|bait|prey|prey|prey|bait|bait|neutral component|neutral component|bait|bait|bait|bait|neutral component|prey|unspecified role|- E2F3 RYBP MI:0018(two hybrid)|MI:0492(in vitro)|MI:0018(two hybrid) 12411495 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|-|MI:0407(direct interaction) (biogrid)|MI:0468(hprd)|(biogrid) BIOGRID_99966|HPRD_6964|BIOGRID_99960 bait|-|bait prey|-|prey BCORL1 RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191992 prey bait BMI1 RYBP MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 10,20601937,22325352,24457600 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint) UniProt_109369|BIOGRID_192031|BIOGRID_307434|BIOGRID_192028|BIOGRID_191832|BIOGRID_191979|MINT_79351|MINT_47488 bait|bait|bait|prey|bait|prey|bait|bait prey|prey|prey|bait|prey|bait|prey|prey FADD RYBP MI:0004(affinity chromatography technology)|MI:0492(in vitro) 11395500 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|- (biogrid)|MI:0468(hprd) BIOGRID_103123|HPRD_10877 prey|- bait|- PCGF3 RYBP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_191978|BIOGRID_191816 prey|bait bait|prey PCGF2 RYBP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_192038|BIOGRID_191803|BIOGRID_191977 bait|bait|prey prey|prey|bait RYBP FBRS MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191995 bait prey RYBP FBRSL1 MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191996 bait prey RYBP GABPB2 MI:0018(two hybrid)|MI:0018(two hybrid) 11953439 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_273846|BIOGRID_273850 prey|prey bait|bait PCGF5 RYBP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_191980|BIOGRID_191845 prey|bait bait|prey CSNK2A1 RYBP MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191997 prey bait RYBP L3MBTL2 MI:0004(affinity chromatography technology) 22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association) (biogrid) BIOGRID_191984 bait prey p53 RYBP MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 19098711 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|(intact) MINT_70363|MINT_40802|MINT_70362|MINT_40803|BIOGRID_116225|UniProt_100172|UniProt_100173 bait|prey|prey|bait|prey|prey|bait prey|bait|bait|prey|bait|bait|prey RYBP ZFP42 MI:0018(two hybrid) 21530438 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0407(direct interaction) (biogrid) BIOGRID_166873 prey bait CSNK2A2 RYBP MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification) 22325352,23455922 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (biogrid)|(biogrid)|(intact) BIOGRID_191998|BIOGRID_276363|UniProt_127595 prey|bait|bait bait|prey|prey E2F6 RYBP MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0018(two hybrid)|MI:0019(coimmunoprecipitation)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0492(in vitro) 11171983,12411495,22325352 taxid:9606(Homo sapiens) taxid:9606(Homo sapiens) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|- (biogrid)|(biogrid)|(biogrid)|MI:0471(mint)|MI:0471(mint)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0468(hprd) BIOGRID_92644|BIOGRID_191986|BIOGRID_92641|MINT_80775|MINT_48992|BIOGRID_92643|UniProt_68646|BIOGRID_92642|BIOGRID_99968|BIOGRID_77901|HPRD_11799 bait|prey|bait|bait|bait|prey|bait|prey|bait|bait|- prey|bait|prey|prey|prey|bait|prey|bait|prey|prey|-

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8N488 P61964 RYBP WDR5 0.332 27705803,26186194,22325352 Q8N488 O95714 RYBP HERC2 0.126 26186194 Q8N488 P04792 RYBP HSPB1 0.286 25277244 Q8N488 P0C0S8 RYBP HIST1H2AM 0.309 17070805 Q8N488 P0CG48 RYBP UBC 0.569 17070805 Q8N488 P31016 RYBP DLG4 0.183 20467438 Q8N488 P46108 RYBP CRK 0.376 25814554 Q8N488 P61244 RYBP MAX 0.126 27705803 Q8N488 P61962 RYBP DCAF7 0.126 27705803 Q8N488 Q06547 RYBP GABPB1 0.623 11953439 Q8N488 Q13158 RYBP FADD 0.21 11395500 Q8N488 Q6VMQ6 RYBP ATF7IP 0.126 26186194 Q8TE76 Q8N488 MORC4 RYBP 0.126 26186194 Q8N488 P25490 RYBP YY1 0.702 10369680,11953439 Q8NHM5 Q8N488 KDM2B RYBP 0.472 27705803,26186194,22325352,23395003 Q8TC84 Q8N488 FANK1 RYBP 0.702 27060496 Q8N488 O75530 RYBP EED 0.126 24457600 Q8N488 P04637 RYBP TP53 0.692 19098711 Q8N488 P00519 RYBP ABL1 0.671 8943360 Q8N488 P19784 RYBP CSNK2A2 0.49 27705803,26186194,22325352,23455922 Q8N488 P63208 RYBP SKP1 0.236 22325352,27705803 Q8N488 Q14781 RYBP CBX2 0.454 10369680 Q8N488 Q86SE9 RYBP PCGF5 0.416 27705803,26186194,22325352 Q93009 Q8N488 USP7 RYBP 0.236 22325352,26186194 Q8WXX7 Q8N488 AUTS2 RYBP 0.472 25519132,27705803,26186194 Q8R023 Q8N488 PCGF1 RYBP 0.236 26496610 Q8TAK5 Q8N488 GABPB2 RYBP 0.523 11953439 Q8N488 Q14209 RYBP E2F2 0.454 12411495 Q9BYE7 Q8N488 PCGF6 RYBP 0.49 27705803,26186194,22325352 Q8N488 Q13387 RYBP MAPK8IP2 0.286 25814554 Q8N488 P35227 RYBP PCGF2 0.49 27705803,26186194,22325352 Q8N488 O00716 RYBP E2F3 0.454 12411495 Q8N488 O75052 RYBP NOS1AP 0.286 25814554 Q8N488 O35730 RYBP RING1 0.236 26496610 Q8N488 Q6W2J9 RYBP BCOR 0.597 27505670,27705803,26687479,22325352,16943429,26186194 Q8N488 P67870 RYBP CSNK2B 0.332 27705803,26186194,22325352 Q8N488 P35226 RYBP BMI1 0.61 27705803,26186194,22325352,24457600,20601937 Q8N488 Q5H9F3 RYBP BCORL1 0.332 27705803,26186194,22325352 Q8N488 Q14186 RYBP TFDP1 0.332 27705803,26186194,22325352 Q969R5 Q8N488 L3MBTL2 RYBP 0.332 27705803,26186194,22325352 Q8N488 Q8IWI9 RYBP MGA 0.332 27705803,26186194,22325352 Q9BSM1 Q8N488 PCGF1 RYBP 0.692 27505670,27705803,26687479,22325352,16943429,26186194 Q9HAH7 Q8N488 FBRS RYBP 0.332 27705803,26186194,22325352 Q9HCM7 Q8N488 FBRSL1 RYBP 0.332 27705803,26186194,22325352 Q923J1 Q8N488 TRPM7 RYBP 0.343 24855944 Q99496 Q8N488 RNF2 RYBP 0.794 27705803,22325352,26496610,16943429,26186194,unassigned1304 Q8N488 O75461 RYBP E2F6 0.925 27705803,26186194,22325352,11171983,12411495 Q8N488 Q00987 RYBP MDM2 0.973 19098711 Q8N488 Q06587 RYBP RING1 0.984 25416956,27705803,16189514,22325352,16943429,26186194,unassigned1304,10369680,17070805 Q92851 Q8N488 CASP10 RYBP 0.376 11395500 Q96MM3 Q8N488 ZFP42 RYBP 0.309 21530438 Q8N488 P83916 RYBP CBX1 0.236 27705803 Q8N488 P68400 RYBP CSNK2A1 0.416 27705803,26186194,22325352 Q8N488 Q15717 RYBP ELAVL1 0.126 19322201 Q8N488 Q13185 RYBP CBX3 0.332 22325352,27705803 Q8N488 Q16254 RYBP E2F4 0.309 12411495 Q8N488 Q3KNV8 RYBP PCGF3 0.416 27705803,26186194,22325352 Q8N488 O14508 RYBP SOCS2 0.309 20543098