DNA & RNA Element - AREsite Gene Name Motif CDS Area ARE Area Evidence Klhl10 ATTTA 108-1934 1943-1947

DNA & RNA Element - microRNA Mirbase Acc miRNA Name Gene ID Gene Symbol miRNA Alignment Alignment Gene Alignment miRNA Start miRNA End Gene Start Gene End Genome Coordinates Conservation Align Score Seed Cat Energy mirSVR Score MIMAT0000137 mmu-miR-126-5p 66720 Klhl10 gcgcaugguuUUCAUUAUUac |: |||||| cucuucauuuAGCUAAUAAaa 3 12 3 23 [mm9:11:100318263-100318283:+] 0.6683 123 0 -3.78 -0.1523 MIMAT0000161 mmu-miR-151-3p 66720 Klhl10 ggaguuccucggagUCAGAUc |||||| uuuagcuaauaaaaAGUCUAa 2 8 10 30 [mm9:11:100318270-100318290:+] 0.6683 120 6 -7.60 -0.4715 MIMAT0004539 mmu-miR-183* 66720 Klhl10 aauaccgggaagccAUUAAGug |||||| uaagcaauaagaauUAAUUCuu 3 9 28 49 [mm9:11:100318288-100318309:+] 0.6683 120 0 -4.12 -0.3878 MIMAT0004542 mmu-miR-191* 66720 Klhl10 cccuugcUUUAGGUUCACGUCg |||| || ||||| uuuuuuuAAAU--AAAUGCAGu 2 16 48 67 [mm9:11:100318308-100318327:+] 0.6683 120 0 -8.93 -0.1118 MIMAT0004578 mmu-miR-300* 66720 Klhl10 uguuuccuauuggaGAGAAGUu ||||||| ------------gcCUCUUCAu 2 9 1 10 [mm9:11:100318261-100318270:+] 0.6683 140 7 -11.17 -0.9983 MIMAT0004627 mmu-miR-20a* 66720 Klhl10 gaaauucacgagcaUUACGUCa ||||||| ucuuuuuuuaaauaAAUGCAGu 2 9 46 67 [mm9:11:100318306-100318327:+] 0.6683 140 7 -11.26 -1.3217 MIMAT0000556 mmu-miR-324-3p 66720 Klhl10 ucgucguggacccCGUCACc |||||| uuuuuaaauaaauGCAGUGu 2 8 50 69 [mm9:11:100318310-100318329:+] 0.6683 120 6 -8.42 -0.3248 MIMAT0004640 mmu-miR-325 66720 Klhl10 aacuauccuccacgaGUUAUUu |||||| aauaaaaagucuaagCAAUAAg 2 8 17 38 [mm9:11:100318277-100318298:+] 0.6683 120 6 -5.55 -0.3513 MIMAT0002107 mmu-miR-466a-3p 66720 Klhl10 agaauacacacgcacAUACAUAu ||||||| --------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0003376 mmu-miR-302c 66720 Klhl10 ggUGACUUUGUACCUUCGUGAa | | ||| :| ||||| | cuAAUAAAAAGUCUAAGCAAUa 2 21 15 36 [mm9:11:100318275-100318296:+] 0.6683 124 0 -6.36 -0.1010 MIMAT0003464 mmu-miR-686 66720 Klhl10 agaaguggcagacccUUCGUUa |||||| gcuaauaaaaagucuAAGCAAu 2 8 14 35 [mm9:11:100318274-100318295:+] 0.6683 120 6 -10.30 -0.2283 MIMAT0004827 mmu-miR-297b-3p 66720 Klhl10 auacccauacacacAUACAUAu ||||||| -------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0004849 mmu-miR-883a-3p 66720 Klhl10 uaugacucucgacaACGUCAau |||||| uuuuuuuaaauaaaUGCAGUgu 3 9 48 69 [mm9:11:100318308-100318329:+] 0.6683 120 0 -6.81 -0.2715 MIMAT0004851 mmu-miR-883b-3p 66720 Klhl10 uaugacucucuacaACGUCAau |||||| uuuuuuuaaauaaaUGCAGUgu 3 9 48 69 [mm9:11:100318308-100318329:+] 0.6683 120 0 -6.81 -0.2691 MIMAT0004864 mmu-miR-297a* 66720 Klhl10 auacccauacacacAUACAUAu ||||||| -------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0004866 mmu-miR-297c* 66720 Klhl10 auacccauacacacAUACAUAu ||||||| -------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0004876 mmu-miR-466b-3p 66720 Klhl10 agaauacacacgcacAUACAUAu ||||||| --------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0005453 mmu-miR-466b-3-3p 66720 Klhl10 agaauacacacgcacAUACAUAa ||||||| --------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -5.04 -0.2372 MIMAT0004878 mmu-miR-466c-3p 66720 Klhl10 agaauacacacgcacAUACAUAu ||||||| --------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0004880 mmu-miR-466e-3p 66720 Klhl10 agaauacacacgcacAUACAUAu ||||||| --------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0004931 mmu-miR-466d-3p 66720 Klhl10 gauacacacgcacAUACAUAu ||||||| ------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0005849 mmu-miR-1191 66720 Klhl10 aucCCGAUGUAUCAUUCUGAc | ||| : | ||||| | aaaGUCUAAGCAAUAAGAAUu 2 19 22 42 [mm9:11:100318282-100318302:+] 0.6683 122 0 -5.23 -0.1147 MIMAT0005854 mmu-miR-467g 66720 Klhl10 uauauacacacacAUACAUAu ||||||| ------------aUAUGUAUc 2 9 1 9 [mm9:11:100307316-100307324:+] 0.4961 140 7 -4.78 -0.2372 MIMAT0009417 mmu-miR-1950 66720 Klhl10 acugguauaggaaucUACGUCu |||||| ucuuuuuuuaaauaaAUGCAGu 2 8 46 67 [mm9:11:100318306-100318327:+] 0.6683 120 6 -8.19 -0.4685 MIMAT0000128 mmu-miR-30a 66720 Klhl10 gaaggucagcuccUACAAAUgu :|||||| uuaaauaaaugcaGUGUUUAaa 3 10 53 74 [mm9:11:100318313-100318334:+] 0.6693 121 0 -5.41 -0.1113 MIMAT0000130 mmu-miR-30b 66720 Klhl10 ucgACUCACAUCCUACAAAUgu | | || || |||||| aaaUAAAUGCAG--UGUUUAaa 3 20 55 74 [mm9:11:100318315-100318334:+] 0.6693 128 0 -5.10 -0.1009 MIMAT0000149 mmu-miR-137 66720 Klhl10 gaugcgcaUAAGAAUUCGUUAUu | || ||||||||| uaauaaaaAGUC-UAAGCAAUAa 2 16 16 37 [mm9:11:100318276-100318297:+] 0.6683 153 7 -11.56 -1.1196 MIMAT0000149 mmu-miR-137 66720 Klhl10 gaugCGCAUAAG-AAUUCG-UUAUu || | ||| || ||| |||| ----GCCUCUUCAUUUAGCUAAUAa 2 20 1 21 [mm9:11:100318261-100318281:+] 0.6683 126 0 -6.09 -1.2414 MIMAT0000153 mmu-miR-141 66720 Klhl10 gguAGAAAUGGUCU--GUCACAAu |:|| | :| | ||||||| uuuUUUUAAAUAAAUGCAGUGUUu 2 20 48 71 [mm9:11:100318308-100318331:+] 0.6683 150 7 -10.58 -1.2788 MIMAT0000165 mmu-miR-155 66720 Klhl10 uggGGAUAGUGUUAAUCGUAAUu :||| :|||| || |||| aagUCUA-AGCAAUAAGAAUUAa 2 21 23 44 [mm9:11:100318283-100318304:+] 0.6683 130 0 -10.28 -0.1625 MIMAT0000215 mmu-miR-186 66720 Klhl10 ucggGUU-UUCCU-CUUAAGAAAc ||| ||| | |||||||| uaagCAAUAAGAAUUAAUUCUUUu 2 19 28 51 [mm9:11:100318288-100318311:+] 0.6683 156 7 -9.24 -1.3089 MIMAT0000248 mmu-miR-30e 66720 Klhl10 gaAGGUCAGUUCC--UACAAAUgu |: | | || | :|||||| uuUUAAAUAAAUGCAGUGUUUAaa 3 21 51 74 [mm9:11:100318311-100318334:+] 0.6693 127 0 -6.70 -0.1102 MIMAT0000514 mmu-miR-30c 66720 Klhl10 cgacucUCACAUCCUACAAAUgu | || || |||||| uaaauaAAUGCAG--UGUUUAaa 3 18 54 74 [mm9:11:100318314-100318334:+] 0.6693 126 0 -4.54 -0.1009 MIMAT0000515 mmu-miR-30d 66720 Klhl10 gaaggucagccccUACAAAUgu :|||||| uuaaauaaaugcaGUGUUUAaa 3 10 53 74 [mm9:11:100318313-100318334:+] 0.6693 121 0 -5.95 -0.1113 MIMAT0000519 mmu-miR-200a 66720 Klhl10 uguagcaauggUCUGUCACAAu | :||||||| uuuuuaaauaaAUGCAGUGUUu 2 12 50 71 [mm9:11:100318310-100318331:+] 0.6683 143 7 -9.75 -1.2788 MIMAT0000667 mmu-miR-33 66720 Klhl10 acguuacguugaugUUACGUg |||||| ucuuuuuuuaaauaAAUGCAg 2 8 46 66 [mm9:11:100318306-100318326:+] 0.6683 120 6 -6.08 -0.2902 MIMAT0000679 mmu-miR-217 66720 Klhl10 aggucagucaaggacUACGUCAu ||||||| ucuuuuuuuaaauaaAUGCAGUg 2 9 46 68 [mm9:11:100318306-100318328:+] 0.6683 140 7 -11.82 -1.3166 MIMAT0004745 mmu-miR-384-5p 66720 Klhl10 uguaacggaUCCUUAACAAAUgu | | | |||||| uuuaaauaaAUGCAGUGUUUAaa 3 15 52 74 [mm9:11:100318312-100318334:+] 0.6693 126 0 -4.94 -0.1124 MIMAT0004896 mmu-miR-590-3p 66720 Klhl10 ugaUCGAAUAUG-UAUU-UUAAu ||: || :| |||| |||| aaaAGUCUAAGCAAUAAGAAUUa 2 19 21 43 [mm9:11:100318281-100318303:+] 0.6683 121 0 -5.18 -1.3175

DNA & RNA Element - TRANSFAC Accession AS Description Species Entrez Pubmed Binding Info G066656 Klhl10 Mus musculus 66720

DNA & RNA Element - RepTar Gene Name miRNA Begin End Profile Klhl10 mmu-miR-20astar beg:57 end:68 pic:3' GAAATTCACGAGCATTACGTCA 5'& |||||||| &5' --------------AATGCAGT 3' Klhl10 mmu-miR-137 beg:23 end:38 pic:3' GATGCGCATAAGAATTCGTTATT 5'& || |||||||||| &5' ----------TC-TAAGCAATAA 3'

DNA & RNA Element - miRNAMap Gene Name Mature miRNA Target Start Target End miRNA 3-5 Alignment Target 5-3 Klhl10 mmu-miR-141 49 72 GGUAGAAAUGGUC---UGUCACAAU |:|||| :||||||| --UUUUUUAAAUAAAUGCAGUGUUU Klhl10 mmu-miR-186 22 52 -UUCGGGUUUUCC--UCU----UAAGAAAC |||:|:||: ||| ||||||| AAAGUCUAAGCAAUAAGAAUUAAUUCUUUU Klhl10 mmu-miR-200a 62 72 UGUAGCAAUGGUCUGUCACAAU :||||||| ------------UGCAGUGUUU Klhl10 mmu-miR-217 45 70 UAGGUCAGUCAAGGACUACGUCAU- ||: |||||||: UUCUUUUUUUAAAUAAAUGCAGUGU Klhl10 mmu-miR-141 64 71 ------------------GGUAGAAAUGGUC---UGUCACAAU |: |:|||| :||||||| AAGCAAUAAGAAUUAAUUCUUUUUUUAAAUAAAUGCAGUGUUU Klhl10 mmu-miR-186 44 51 --------------UUCGGGUU-----UUCCUC-UUAAGAAAC |||:|:|| ||| |||||||| AUUUAGCUAAUAAAAAGUCUAAGCAAUAAGAAUUAAUUCUUUU Klhl10 mmu-miR-200a 64 71 UGUAGCAAUGGUC---------------------UGUCACAAU :||||||| AAGCAAUAAGAAUUAAUUCUUUUUUUAAAUAAAUGCAGUGUUU Klhl10 mmu-miR-217 61 68 U-------------------AGGUCAGUCAAGGACUACGUCAU ||: |: |||||||: UCUAAGCAAUAAGAAUUAAUUCUUUUUUUAAAUAAAUGCAGUGU

DNA & RNA Element - RAID2 Gene Name RAID ID Interactor 1 Category 1 ID 1 Interactor 2 Category 2 ID 2 Methods Score Klhl10 RAID00140377 mmu-miR-30e-5p miRNA MIMAT0000248 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID00522317 mmu-miR-155-5p miRNA MIMAT0000165 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID01074024 mmu-miR-33-5p miRNA MIMAT0000667 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID01261337 mmu-miR-186-5p miRNA MIMAT0000215 Klhl10 mRNA 66720 Prediction 0.2202 Klhl10 RAID01367880 mmu-miR-384-5p miRNA MIMAT0004745 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID01920438 mmu-miR-30c-5p miRNA MIMAT0000514 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID01929602 mmu-miR-590-3p miRNA MIMAT0004896 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID02244659 mmu-miR-30b-5p miRNA MIMAT0000130 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID02271416 mmu-miR-141-3p miRNA MIMAT0000153 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID02553185 mmu-miR-30a-5p miRNA MIMAT0000128 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID02670426 mmu-miR-137-3p miRNA MIMAT0000149 Klhl10 mRNA 66720 Prediction 0.2381 Klhl10 RAID02791351 mmu-miR-217-5p miRNA MIMAT0000679 Klhl10 mRNA 66720 Prediction 0.2202 Klhl10 RAID03436320 mmu-miR-200a-3p miRNA MIMAT0000519 Klhl10 mRNA 66720 Prediction 0.1828 Klhl10 RAID03863451 mmu-miR-30d-5p miRNA MIMAT0000515 Klhl10 mRNA 66720 Prediction 0.1828