PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Socs3 Crkl 15173187 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G Prdx1 Crkl 20697350 biogrid,intact exp P Crkl Ywhae 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Nckipsd 20697350 biogrid,intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Hspd1 20697350 biogrid,intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Cblb 12697763 biogrid exp, ortho Crkl Inpp5d 11031258 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G Crkl Bcar1 8978305 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Gab1 10871282 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Pxn 8978305 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Sos1 8978305 biogrid exp, ortho P G G G G G G G G G Zap70 Crkl 12697763 biogrid exp, ortho GP G G G G G G G G G G G G G Cbl Crkl 11804588,8978305,9067577,11031258,10391678,11069064 biogrid,i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Protein Rapgef1 8978305,12671687,15062102,12697763,16443220,11069064 biogrid,i2d exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Dab1 15062102 biogrid,i2d,mint,intact exp, ortho G G G G G G G G Abl1 Crkl 8978305 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pik3r1 Crkl 11031258 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Epor Crkl i2d exp, ortho G G G G G G G G G G G G G G G G G Crkl Trap1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Gabarapl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnm2 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fcgr1 Crkl ortho G G G G G G G G G G G G G Crkl Ubl5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Evl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Ogt ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Bcr ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Sos2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Cep170 ortho Crkl Yy1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Hnrnph2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Edc3 ortho P Crkl Prr3 ortho G G G G G G G G G G G G G G G G G G G Kit Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Itgb1 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dok2 Crkl ortho G G G G G G G G G G G G Crkl Hip1r ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Erbb2 ortho P G G G G G G G G G G G G Crkl Sgk223 ortho Crkl Grb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Rin3 ortho Crkl Dcp2 ortho Lck Crkl ortho G G G G G G G G G G G G G G Mov10 Crkl ortho G G G G G G G G G G G G G G G G G G G G Vav1 Crkl ortho G G G G G Crkl Arel1 ortho Ikbkb Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Map4k1 ortho P G G G G G G Crkl Bag3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl MCG12570, Protein Pnrc1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Tnik ortho P Gp6 Crkl ortho Socs1 Crkl ortho Crkl Elmo2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Insr Crkl ortho P G G Crkl Shc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat5a Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G Hck Crkl ortho G G G G G G G G G G G G G G G G G G G G Crkl Mapk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Impact Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyb Crkl ortho G G G G G G G G G G G G G G G G G G Crkl Lmna ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Mapk10 ortho P G G G G G G G G G G G G Dock5 Crkl ortho P G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Mink1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pik3r2 Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Igf1r ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Map4k5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Sephs1 ortho P Nedd9 Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G Protein Kidins220 Crkl ortho P Crkl Dusp10 ortho G G G G G G G G G G G G G G G G G G G Map2k4 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Grap ortho Grn Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdgfra Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Arhgef5 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G Ppfibp2 Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ifnar1 Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Dcbld2 ortho G G G G G G G G G G G G G G G G G Crkl Shank3 ortho G G G G G G G G G G G G G G G G G G G G G G G Crkl Msl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Wipf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Erbb3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Ltbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Was ortho G G G G G G G G G Bik Crkl ortho G G G G G G G G G G G G G Crkl Crk ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Dok1 ortho G G G G G G G G G G G G G G G G G G G G Crkl Lama5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Crkl Dcp1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Tmem168 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Pld1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Pten Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ephb6 Crkl ortho G G G G G G G G G G Apob Crkl ortho P G G G G G G G G Crkl Arhgef6 ortho Crkl Dual specificity phosphatase 9, Dual specificity phosphatase 9, isoform CRA_a, Dual-specificity MAP kinase phosphatase-4, Protein Dusp9 ortho G Crkl Dock2 ortho GP G G G G G G G G G Crkl Ksr1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Brd8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tyr Crkl ortho G G G Crkl Raf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Cd34 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Flt1 Crkl ortho G G G G G G G G G G G G G G G G G G Crkl Mapk8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat3 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map3k4 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Telo2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Erbb4 ortho P Crkl Wac ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdcd6 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Plekha1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptpn11 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Garem ortho Crkl Edc4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Plscr1 ortho G G G G G G G G G G G G G G G G G G G G G G G Eps15 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aox1 Crkl ortho GP G G G G G G G G G G G G G G G G G Ptk2 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Dock1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat5b Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Cul7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Clic4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Marf1 ortho P Vcam1 Crkl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Sash1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Tgfb1i1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Cdc42bpa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Khdrbs1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Polr1d ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Egfr ortho GP G G G G G G G G G G G G G G G G G Crkl Tns2 ortho G G G G G G G G G G G G G G G G G G G G G Protein Cnksr1 Crkl ortho Crkl Elavl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Notch2 Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Mpzl1 ortho Crkl Gorab ortho Crkl Arhgap32 ortho Crkl Megf6 ortho Crkl Map3k12 ortho G G G G G G G G G G G G G G Crkl Gab2 ortho G G G G G G Crkl Phc2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Syk ortho GP G G G G G G G G G G G G G G G G Lyn Crkl ortho P Pdgfrb Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Tyk2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Rpl31 ortho P Crkl Abi1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Grap2 Crkl ortho Crkl Mapk9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Ninl ortho Crkl Etv6 ortho P G G G G G G G G G G G G G G G G Crkl Ntrk1 ortho Crkl Ddx6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Usp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Blnk ortho G G G G G G G G G G G G G G G G G G G G G G G Odf2 Crkl ortho G G G G Crkl Pik3cg ortho G G G G G G G G G G G G Crkl Peak1 ortho G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P47941 - 7545163,9344843 - X 2 P47941 - 11443118 - X 2 P47941 P0CG50 affinity chromatography technology 12697763 physical association X 2 P47941 affinity chromatography technology 12697763 physical association X 2 P47941 pull down 8978305 direct interaction X 2 P47941 two hybrid 8978305 direct interaction X 2 P47941 affinity chromatography technology 8978305 physical association X 2 P47941 affinity chromatography technology 8978305 physical association X 2 P47941 P35700 affinity chromatography technology 20697350 physical association X 2 P47941 P97318-3 affinity chromatography technology 15062102 physical association X 2 P47941 P97318-3 affinity chromatography technology 15062102 physical association X 2 P47941 affinity chromatography technology 15062102 physical association X 2 P47941 affinity chromatography technology 11069064 physical association X 2 P47941 Q3TP23 pull down 11031258 direct interaction X 2 P47941 affinity chromatography technology 16443220 physical association X 2 P47941 affinity chromatography technology 12671687 physical association X 2 P43404 P47941 affinity chromatography technology 12697763 physical association X 2 Q8R4N0 P47941 affinity chromatography technology 11804588 physical association X 2 P22682 P47941 affinity chromatography technology 8978305 physical association X 2 P22682 P47941 affinity chromatography technology 10391678 physical association X 2 P22682 P47941 affinity chromatography technology 10391678 physical association X 2 P22682 P47941 affinity chromatography technology 9067577 physical association X 2 P22682 P47941 affinity chromatography technology 11069064 physical association X 2 P22682 P47941 pull down 11031258 direct interaction X 2 P63038 P47941 affinity chromatography technology 20697350 physical association X 2 Q62245 P47941 affinity chromatography technology 8978305 physical association X 2 P47941 Q8VI36 affinity chromatography technology 8978305 physical association X 2 P47941 Q61140-2 affinity chromatography technology 8978305 physical association X 2 P47941 Q9ES52-4 pull down 11031258 direct interaction X 2 P47941 Q9ES52-4 pull down 11031258 direct interaction X 2 P47941 Q9ES52-4 affinity chromatography technology 11031258 physical association X 2 P47941 Q9ES52-4 affinity chromatography technology 11031258 physical association X 2 B9EKI5 P47941 affinity chromatography technology 12697763 physical association X 2 B9EKI5 P47941 affinity chromatography technology 12697763 physical association X 2 Q9ESJ4 P47941 affinity chromatography technology 20697350 physical association X 2 P47941 anti bait coimmunoprecipitation 10608804 association C 3 P47941 cosedimentation 16615898 colocalization C 1216 P47941 pull down 20697350 association C 4 P97318 P47941 pull down 15062102 association X 2 P97318 P47941 pull down 15062102 association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Cbl Crkl MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 10391678,11031258,11069064,8978305,9067577 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_327705|BIOGRID_329254|BIOGRID_322763|BIOGRID_323352|BIOGRID_323350|BIOGRID_331234 prey|prey|prey|prey|bait|prey bait|bait|bait|bait|prey|bait Crkl Clybl MI:0004(affinity chromatography technology) 11804588 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322731 prey bait Crkl Inpp5d MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11031258 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_331237|BIOGRID_331238|BIOGRID_331236|BIOGRID_331233 bait|prey|prey|bait prey|bait|bait|prey Crkl Nckipsd MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0027(cosedimentation) 16615898,20697350 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0403(colocalization) (biogrid)|(intact)|(intact)|(intact)|(intact) BIOGRID_322835|UniProt_108791|UniProt_185041|UniProt_172900|UniProt_167114 bait|bait|bait|bait|neutral component prey|prey|prey|prey|neutral component Crkl Pxn MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology) 16615898,8978305 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid) UniProt_167131|UniProt_167130|UniProt_167114|BIOGRID_322762 neutral component|neutral component|neutral component|bait neutral component|neutral component|neutral component|prey Prdx1 Crkl MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation) 16615898,20697350 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_167131|UniProt_167130|UniProt_108791|UniProt_185041|UniProt_172900|BIOGRID_322833|UniProt_167114 neutral component|neutral component|prey|prey|prey|prey|neutral component neutral component|neutral component|bait|bait|bait|bait|neutral component Crkl Cblb MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12697763 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_321797|BIOGRID_321798 prey|bait bait|prey Ubc Crkl MI:0004(affinity chromatography technology) 12697763 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321799 prey bait Crkl Hspd1 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation) 16615898,20697350 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_167131|UniProt_167130|UniProt_108791|UniProt_185041|UniProt_172900|BIOGRID_322834|UniProt_167114 neutral component|neutral component|bait|bait|bait|bait|neutral component neutral component|neutral component|prey|prey|prey|prey|neutral component Zap70 Crkl MI:0004(affinity chromatography technology) 12697763 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321801 prey bait Pik3r1 Crkl MI:0004(affinity chromatography technology) 11031258 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_331235 prey bait Abl1 Crkl MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 8978305 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_322757|BIOGRID_322759|BIOGRID_322758 prey|prey|bait bait|bait|prey Crkl Dab1 MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 15062102 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association) (intact)|(biogrid)|(intact)|MI:0471(mint)|(biogrid)|MI:0471(mint) UniProt_163604|BIOGRID_325794|UniProt_163605|MINT_80126|BIOGRID_325792|MINT_79637 unspecified role|bait|unspecified role|unspecified role|prey|unspecified role unspecified role|prey|unspecified role|unspecified role|bait|unspecified role Crkl Rapgef1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 11069064,12671687,12697763,15062102,8978305 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_325795|BIOGRID_321800|BIOGRID_320068|BIOGRID_322760|BIOGRID_329253 bait|bait|bait|bait|bait prey|prey|prey|prey|prey Crkl Bcar1 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology) 16615898,8978305 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association) (intact)|(biogrid) UniProt_167130|BIOGRID_322764 neutral component|bait neutral component|prey Crkl Sos1 MI:0004(affinity chromatography technology) 8978305 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322761 bait prey

PPI - HINT Gene A Gene B PMID Method Quality ABL1 CRKL 8978305,8978305,8978305 0004,0018,0096 LC EPOR CRKL 11443118,11443118,11443118,11443118 0405,0019,0004,0047 LC CBL CRKL 9344843,9344843,7545163,7545163 0019,0045,0045,0019 LC CRKL YWHAE 16615898 0027 LC CRKL GAB1 10871282 0018 LC SOCS3 CRKL 15173187 0007 LC ABL1 CRKL 8978305,8978305,8978305 0004,0018,0096 LC UBC CRKL 12697763 0004 LC EPOR CRKL 11443118,11443118,11443118,11443118 0405,0019,0004,0047 LC CBL CRKL 8978305,10391678,11031258,11804588,9067577,11069064 0004,0004,0096,0004,0004,0004 LC PIK3R1 CRKL 11031258 0096 LC PRDX1 CRKL 20697350,20697350 0004,0096 LC ZAP70 CRKL 12697763 0004 LC CRKL HSPD1 20697350,20697350 0004,0096 LC CRKL DAB1 15062102,15062102 0004,0096 LC CRKL CBLB 12697763 0004 LC CRKL BCAR1 8978305 0004 LC CRKL SOS1 8978305 0004 LC CRKL PXN 8978305 0004 LC CRKL RAPGEF1 15062102,8978305,12697763,16443220,11069064,12671687 0004,0004,0004,0004,0004,0004 LC CRKL INPP5D 11031258,11031258 0096,0004 LC CRKL NCKIPSD 20697350,20697350 0004,0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P62259 P47941 YWHAE CRKL 0.081 16615898 P47941 P00520 CRKL ABL1 0.623 8978305 Q9ES52 P47941 INPP5D CRKL 0.702 11031258 Q3TTA7 P47941 CBLB CRKL 0.523 12697763,27474268 Q3U1F9 P47941 PAG1 CRKL 0.236 26512138 Q9ESJ4 P47941 NCKIPSD CRKL 0.332 20697350 P63038 P47941 HSPD1 CRKL 0.332 20697350 P47941 P22682 CRKL CBL 0.853 9067577,27474268,11069064,10391678,11031258,11804588,8978305 P47941 P35700 CRKL PRDX1 0.332 20697350 P47941 P13379 CRKL CD5 0.126 27474268 P47941 P26450 CRKL PIK3R1 0.309 11031258 P47941 P42337 CRKL PIK3CA 0.126 27474268 P47941 P43404 CRKL ZAP70 0.21 12697763 P97318 P47941 DAB1 CRKL 0.507 15062102 Q61140 P47941 BCAR1 CRKL 0.21 8978305 Q62245 P47941 SOS1 CRKL 0.21 8978305 Q8VI36 P47941 PXN CRKL 0.21 8978305