PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Irf1 Ube2i 18955028 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pou5f1 Ube2i 17097055 biogrid exp Ube2i Mthfs 22303332 biogrid exp P Rel Ube2i 9223278 innatedb exp G G G G Myd88 Ube2i 15102471 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Irf2 Ube2i 18955028 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Smap2 18413247 innatedb exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Ube2i 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gata1 Ube2i 15173587 biogrid exp G G G G G G G Nfatc2ip Ube2i 20077568 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sox2 Ube2i 17097055 biogrid exp G G G G G G G G G G G Ube2i Nr2c1 17187077 dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Irf8 Ube2i 18955028 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G Lmna Ube2i 21327095 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ikzf1 15767674 intact exp, ortho P G G G G G Jun Ube2i i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Dach1 i2d exp, ortho G G G G G G G G G G G Fas Ube2i 11034606,9257699 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G Ube2i Hif1a 17981124 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Casp8ap2 23673342 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tcf3 Ube2i 12200424,9409784,22354994 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctbp2 Ube2i 16940173 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ube2i 20077568 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikzf3 Ube2i 15767674 intact exp, ortho Ube2i Uimc1 17698038 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sumo3 20077568 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pias3 Ube2i 12387893 innatedb,biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ncor1 16421255 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rangap1 Ube2i 11792325,15094046 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ppm1j i2d exp, ortho Egr2 Ube2i 21836637,doi:10.1038/embor.2011.152 mint,intact exp, ortho G G G G G G G G G Ube2i Nfkbia 9223278 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mdm2 Ube2i 21183956 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rpf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ikbke ortho G G G G G G G G G G G G G Ube2i Taf10 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rbbp5 ortho Ube2i Rbms1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Traf6 ortho G G G G G G G G G G G G G G G G G G G G Ube2i Upf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rorb ortho G G G G G G G G Ube2i Arl13b ortho Ep300 Ube2i ortho P Ube2i Tatdn1 ortho Ube2i Rad54b ortho Ube2i Akap9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Ube2i Xiap ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zac1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sox6 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ddx1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ddx5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Traf4 ortho G G G G G G G G G G G G G G G G G G Ube2i Hgs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mta1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Znf24 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bhlhe40 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bmi1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tsg101 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rcbtb2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Eif1b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arnt Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Atxn1 Ube2i ortho Crem Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rrs1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tcf4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xbp1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cbx4 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Park7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsf2 Ube2i ortho Ube2i Bcl11a ortho G G G G G G G G G G G G G G G G G G G G Rc3h2 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nvl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Taf1 ortho Cdh4 Ube2i ortho G G G G G G G G G Ube2i Whsc1l1 ortho Sept2 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Nup153 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Suz12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zeb2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hnrnpll ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Srebf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sae1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ptch1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Kat2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atf2 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Flnc ortho GP G G G G G G G G G G Ube2i Rnf10 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Lnx2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Camsap2 ortho Ube2i Nop58 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tsr1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hira ortho G G G G G G G G G G G G G G G G G G G G G G Sumo2 Ube2i ortho P Cops5 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Shfm1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Gfi1 ortho G G G G G G Zbtb7a Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hnrnpm ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nsf Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rad54l2 ortho G G G G G G G G G G G G G G Ube2i Rnf40 ortho P Slc2a4 Ube2i ortho G G G G G G G G G G G G G G G G G G G G Ube2i Sh3glb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnmt3a Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tmem209 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crebbp Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Bcam ortho GP G G G G G G G G G G G G G G G G G G G G G G Parp1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Wnk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nup85 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hspa4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Noc2l ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Uncharacterized protein C18orf25 homolog ortho Dnmt3b Ube2i ortho G G G G G G G G G G G Setx Ube2i ortho Krt19 Ube2i ortho GP G G G G G G G G G G G G G Dhx9 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctbp1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Capn2 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp63 Ube2i ortho G G G G G G G Ube2i Kcnip3 ortho G G G G G G G Drg1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Chmp1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mkl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Glul Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rnf185 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Abce1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Fhl3 ortho G Ube2i Slx4 ortho Ube2i Arfgap2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl8 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nfatc1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G Ube2i Mvk ortho GP G G G G G G G G G G G G G G G G G Hnf4a Ube2i ortho G G G G G G G G G G G Lmo2 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl7 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cul2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Dnm1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Taf5 ortho Ube2i Myh9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Agtrap ortho GP G G G G G G G G G G G G G G G G Ube2i Rfc5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Protein Golgb1 Ube2i ortho P Ube2i Carm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf1a Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Prkra ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pa2g4 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hdac4 ortho Ube2i Snd1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Seh1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Sept1 Ube2i ortho P G G G G G G G G Ube2e1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trps1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mecom ortho G Ube2i Krit1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Atf3 ortho G G G G G G G G G G G G G G G G G Ube2i Habp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Egf Ube2i ortho GP G G G G G G G G G G G G G Ube2i Nup35 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Psmd13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Kcnb1 ortho G G G G G G G G G G G G G Ube2i Rnf111 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tp73 ortho G Ube2i Hipk3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cog1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Kpnb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ran Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map3k1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Siah2 ortho G G G G G G G G G G G G G G G G G G G G G Ube2i Mitf ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G MCG21756, isoform CRA_b, Nup205 protein, Protein Nup205 Ube2i ortho P Ube2i Trim54 ortho G G G G G G G Ube2i Sart1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rad52 Ube2i ortho G G G G G G G G G G G G G G G G G G Ube2i Psmd9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rps6ka6 ortho P Ube2i Chuk ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sp3 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nol6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Etv1 Ube2i ortho Ube2i Kctd5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sarnp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myb Ube2i ortho G G G G G G G G G G G G G G G Pten Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nop56 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkar1b Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G Ctnna1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rcc1 ortho P G G G G G G G G G G G G G G G G Ube2i Csnk2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Xpo7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wee1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Topors ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stmn2 Ube2i ortho P G G G G G G G G G G G G G Ube2i Puf60 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Camk2d ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Uap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Xpa ortho G G G G G G G G G G G G G G G G G G G G G G G Ube2i Edf1 ortho P Nr3c1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cftr Ube2i ortho G G G G G G G G Ube2i Mef2c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zmym2 ortho P Ube2i Asf1b ortho G G G G G G G G G G G G G G G G Ube2i Unc119 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tsc22d3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fos Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Grb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ripk2 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G Pnn Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nr1h2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ddx52 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbp Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Pdzk1 ortho G G G G G G G G Ube2i Ranbp9 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ndufa7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cd2ap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Xpo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ddx19a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cebpe ortho Ube2i Mul1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hnrnpc ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcna Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc3 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nin ortho G G G G G G G G G G G G G G G G G G G G G Ube2i Nono ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Peli1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tfap2a Ube2i ortho G G G G G G Ube2i Ddx54 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nr1i2 Ube2i ortho G G G G G Ube2i Rwdd3 ortho G G G Ube2i Kctd1 ortho G G G G G G G G G G G G G G G G G G G G G G Ube2i Bend5 ortho Ube2i Cdkn2a ortho Ube2i Cdk2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Cdk1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G Ube2i Sfpq ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnm1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G Gmeb2 Ube2i ortho Eif3a Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ski ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rbm14 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Jmjd6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Apex1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Specc1l ortho Pias1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Fancm ortho G G Nr5a2 Ube2i ortho G G G G G G G Calu Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Chek1 Ube2i ortho G G G G G G G G G G G G G G G Rb1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Thrb Ube2i ortho G G G G G G Esr1 Ube2i ortho G G G G G Grik2 Ube2i ortho G G G G Ube2i Kat5 ortho Ube2i Tdp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hipk1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Aurka ortho G G G G G G G G G G G G G G Ube2i Arntl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Chek2 ortho G G G G G G G G G G G G G G G G G G G G Ube2i Ipo13 ortho Ube2i Smarca2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Echs1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cdca8 ortho Ube2i Nup93 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Socs6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Pak4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Dtx3l ortho P Protein Chd3 Ube2i ortho P Ruvbl1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Bop1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Traf3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sept4 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Skil ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 Ube2i ortho P G G G G G G G G G G G G G G Ube2i Ndufa2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ddx18 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pex10 Ube2i ortho Ube2i Taf12 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sugp1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aaas Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Crabp2 Ube2i ortho G G G G G G G Ube2i Prkaa2 ortho P Zcchc7 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Znf451 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ssrp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Chmp4b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Blmh ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tp53bp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fasn Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tab2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cebpd ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sympk ortho P Xrcc5 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nop2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mrm1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Chd4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Gmeb1 ortho G G G G G G G G G G G G G G G G G G G G G G Ube2i Pdlim7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Atf7ip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Clk2 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Slc2a1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Srsf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim27 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Daxx Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nsdhl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nup98 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wt1 Ube2i ortho G G G G G Ube2i Cltc ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Snrnp200 ortho P Ube2i Tfap2b ortho G G G G Ube2i Rnf115 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hnrnpu ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Smad4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Supt7l ortho Ube2i Pias2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ttn Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G Ube2i Znf668 ortho Ube2i Mrpl53 ortho P Ppara Ube2i ortho G G G G G G G G G G G G G G Ube2i Uba1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ykt6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sall1 ortho G G Ube2i Setbp1 ortho Ube2i Mre11a ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Gcm1 ortho G Polr1c Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zbtb8a ortho G G G G G G G G G G G G G G G G G G Ube2i Eif3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Prpf8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i MCG14257, Protein Hsf2bp ortho Ube2i Tshz2 ortho P G G G G G G G G G G G Ube2i Trim29 ortho P G G G G G G G G G Ube2i Nup210 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mgrn1 ortho Maf Ube2i ortho G Ube2i Rnf128 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hip1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Ube2i ortho G G G G G G G G G G G G G Tkt Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brd7 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd4 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i MCG144734, isoform CRA_a, Protein Zfp420, Zfp420 protein ortho Ube2i Sox10 ortho G G G G G G G G G G G G G G Pcgf2 Ube2i ortho G G G G G Ube2i Coro2a ortho G G G G G G G G G G G G G G G G G G G G G G Ube2i Trip13 ortho G G G G G G G G G G G G G G Ube2i Top2a ortho G G G G G G G G G G G G G G G G G G G G G G Ube2i Srebf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Gtpbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mapk1ip1l ortho Ube2i Kif1b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Phactr4 ortho P Ube2i Eif2ak4 ortho GP G G G G G G G G G G G G G G G G G G G Ube2i Sept5 ortho P Ube2i Pml ortho GP G G G G G G G G G G G G G G G G G G G G Ube2i Ddx24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Uchl1 ortho P G G G G G G G G G G G G G G G G G G Casp2 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zyx ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Arid3a ortho G G G G G G G G G G G G G G G G G G G G G G G G G Blm Ube2i ortho G G G G G G Ube2i Nup155 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Prkdc ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Exosc9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hdac7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nmi Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sox9 ortho G G G G G G G G G G G G G G G G G G Fli1 Ube2i ortho G G G G G G G G G G G G G G G G G Ube2i Naa11 ortho P G Ube2b Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rbbp6 ortho G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Srf ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Pias4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ubxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim63 ortho Ube2i Iqgap1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sucla2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspb1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Phc1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sept6 ortho P G G G G G G G G G G G G G G G G G Ube2i Cblc ortho G G G G G G G G G G G G G G Rxra Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hnrnpk Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Uba2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tcerg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hspb2 ortho G G G G G G G G G G G G G G Ube2i Nr3c2 ortho Ube2i Hipk2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mapre1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rad51 ortho G G G G G G G G G G G G G Ube2i Rnf4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sh3kbp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Atxn7 ortho G G G G G G G G G G G G Ube2i Smad3 ortho G G G G G G G G G G G G G G G Tp53 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Anxa1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ets1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zmynd11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zhx1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Med7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Top2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Pes1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map2k1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Snip1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Gtf2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zbtb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nup214 ortho P Ube2i Stra13 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cacybp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim33 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sept3 ortho P G G G G G G G G G G G G G G G G Ube2i Cdc37 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Cdc42bpa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ofd1 ortho G G G G G G G G G G G G G G G G Snrpd2 Ube2i ortho P Sema6a Ube2i ortho G G G G G G G G Ube2k Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Add3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sept7 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Bag3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxl2 Ube2i ortho Birc3 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Adar ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nr1d2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cldn2 Ube2i ortho G G G G G G G G G G G G Ube2i Tollip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sirt1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Sept9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim41 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hdac5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cox5a Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hnrnpd ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Csde1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Kdm1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Chfr ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G App Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim72 ortho Ube2i Prkar1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim21 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Matr3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i March5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Klf5 ortho G G G G G G G G G G G G G G G G G G G G G G G G Tsc22d1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mkrn3 ortho Ube2i Ndc1 ortho GP G G G G G G G G G G G G G G G G G G G Ube2i Rnf133 ortho Ppargc1a Ube2i ortho G G G G G G G G G G G G G G G G G G G G G Ube2i Tax1bp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Zmym5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Uhrf2 ortho Ube2i Sox4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxm1 Ube2i ortho G G G G G G G G Ube2i Protein Zbtb26, Zinc finger and BTB domain containing 26, Zinc finger and BTB domain containing 26, isoform CRA_b ortho Ube2i Dzip3 ortho Setdb1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Isy1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tsnax ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Ddx21 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Txn Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mtap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tfap2c ortho G G G G G Ube2i Kctd15 ortho P Ube2i Mef2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsf1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Wnk2 ortho GP G G G G G G G G G G G G G G G G G G G G Nr5a1 Ube2i ortho G G G G G G Ube2i Ncor2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tcf7l2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nat10 ortho P Ube2i Sf3b4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Birc7 Ube2i ortho Ube2i Znrd1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Thy1 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G MCG19772, Protein Trim55 Ube2i ortho Ube2i Polr1b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Etv6 ortho P G G G G G G G G G G G G G G G G Ube2i Setd8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Top1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fhit Ube2i ortho GP G G G G G G G G G G G G G G G G G G Ube2i Golga2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Protein Trim38 ortho Ube2i Nup107 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rad18 ortho G G G G G G G Elk1 Ube2i ortho G G G G G Ube2i Creb1 ortho GP G G G G G G G G G G G G G G G G G G G G G Ube2i Ppp2r5c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fmr1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Prpf40a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Grm8 Ube2i ortho G G G G G Usp25 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Edaradd ortho G G G G G Thra Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kcnk1 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G Ube2i Phf19 ortho G G G G G G G G G G G Ube2i Grip1 ortho G G G G G G G G G G G Ube2i Dtl ortho G G G G G G G G G G G Ube2i Scnn1a ortho G G G G G G G G G G G G G G G G G G Ube2i Usp8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Mybbp1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Znf106 Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Slc9a1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim28 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Klhl12 ortho Ube2i Nip7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Hic1 ortho G G G G G G G G G G G G G G G G G G G G G G Siah1a Ube2i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Xrcc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Nudcd3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Tnrc6a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif6 Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2i Rnf144b ortho G Aurkb Ube2i ortho G G G G G G G G G G G G G Ube2i Satb1 ortho G G G G G G G G G G G G G G G G G G G G G G G Ube2i Trim23 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Csn2 Ube2i ortho G G G G G G Des Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G Ube2i Xrn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Pparg Ube2i ortho G G G G G G G G G G G G G G G Ube2i Kcna5 ortho G G G G G G G G G G G G Ar Ube2i ortho G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q06609 P63280 - 10666456 - X 2 Q06609 P63280 - 10666456 - X 2 P63280 - 12633878 - X 2 P63280 O75030-2 - 10694430 - X 2 P63280 P63166 - 10666456 - X 2 P63280 O75030-2 - 10694430 - X 2 P19357 P63280 - 10655495 - X 2 P19357 P63280 - 10655495 - X 2 P43351 P63280 - 10666456 - X 2 P63280 P05627 - 10788439 - X 2 Q9QYB2 P63280 - 11025202 - X 2 P11167 P63280 - 10655495 - X 2 O09130 P63280 pull down 20077568 direct interaction X 2 P49792 P63280 pull down 11792325 direct interaction X 2 P63280 E9PVV2 affinity chromatography technology 22354994 physical association X 2 P63280 P63166 enzymatic study 15094046 direct interaction X 2 P63280 E9PVV2 two hybrid 12200424 direct interaction X 2 P63280 Q96BH3 two hybrid 9409784 direct interaction X 2 P63280 A0A024R3Z2 two hybrid 20543865 direct interaction X 2 P63280 Q9Y692 pull down 11812797 direct interaction X 2 P63280 Q9UKD1 pull down 11812797 direct interaction X 2 P63280 P06536 pull down 11812797 direct interaction X 2 P63280 two hybrid 16940173 direct interaction X 2 P63280 pull down 16940173 direct interaction X 2 P63280 Q08211 two hybrid 15312759 direct interaction X 2 P63280 P48432 enzymatic study 17097055 direct interaction X 2 P63280 P48678 affinity chromatography technology 21327095 physical association X 2 P63280 two hybrid 17698038 direct interaction X 2 P63280 affinity chromatography technology 17698038 physical association X 2 P63280 pull down 17698038 direct interaction X 2 P23906 P63280 two hybrid 18955028 direct interaction X 2 P63280 enzymatic study 17097055 direct interaction X 2 P63280 Q3U5M1 two hybrid 18955028 direct interaction X 2 P63280 P23611 two hybrid 18955028 direct interaction X 2 P63280 Q3U5M1 pull down 18955028 direct interaction X 2 P63280 Q3U5M1 enzymatic study 18955028 direct interaction X 2 P63280 P25445-6 two hybrid 10068040 direct interaction X 2 P63280 X6REB3 two hybrid 9409784 direct interaction X 2 P63280 two hybrid 16421255 direct interaction X 2 P63280 P25446 two hybrid 9257699 direct interaction X 2 P63280 Q9H2X6-2 pull down 10535925 direct interaction X 2 P63280 Q9H2X6-2 two hybrid 10535925 direct interaction X 2 P63280 P23497-7 pull down 11792325 direct interaction X 2 P63280 P23804 enzymatic study 21183956 direct interaction X 2 P11166 P63280 pull down 10655495 direct interaction X 2 P14672 P63280 pull down 10655495 direct interaction X 2 P63280 Q505F1 anti bait coimmunoprecipitation 17187077 direct interaction X 2 P63280 Q505F1 two hybrid 17187077 direct interaction X 2 P63280 Q505F1 pull down 17187077 direct interaction X 2 P63280 cosedimentation 16615898 colocalization C 1216 P22366 P63280 two hybrid 15102471 physical association X 2 P15923 P63280 two hybrid 9409784 physical association X 2 P15923 P63280 two hybrid 9409784 physical association X 2 O08900 P63280 two hybrid 15767674 physical association X 2 P63280 P25446 two hybrid 11034606 physical association X 2 P63280 Q03267 two hybrid 15767674 physical association X 2 P63280 P08152 two hybrid 21836637 physical association X 2 P63280 P08152 pull down 21836637 direct interaction X 2 P63280 P15806-2 two hybrid 9409784 physical association X 2 P15923-2 P63280 pull down 9409784 physical association X 2 P19357 P63280 two hybrid 10655495 - X 2 P19357 P63280 coimmunoprecipitation 10655495 - X 2 P19357 P63280 coimmunoprecipitation 10655495 - X 2 P19357 P63280 coimmunoprecipitation 10655495 - X 2 P11167 P63280 coimmunoprecipitation 10655495 - X 2 P11167 P63280 coimmunoprecipitation 10655495 - X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ube2i Ncor1 MI:0096(pull down) 16421255 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_329465 prey bait Ctbp2 Ube2i MI:0027(cosedimentation)|MI:0018(two hybrid)|MI:0018(two hybrid) 16615898,16940173 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(biogrid)|(biogrid) UniProt_167137|BIOGRID_313882|BIOGRID_313884 neutral component|bait|bait neutral component|prey|prey Ube2i Irf8 MI:0018(two hybrid) 18955028 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_322305 prey bait Sox2 Ube2i MI:0415(enzymatic study) 17097055 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_315809 prey bait Ube2i Nr2c1 MI:0006(anti bait coimmunoprecipitation) 17187077 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) MI:0465(dip) DIP_352 - - Tcf3 Ube2i MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0018(two hybrid) 12200424,22354994,9409784 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact)|(intact) BIOGRID_325630|BIOGRID_320657|UniProt_177225|UniProt_135072 bait|bait|null|null prey|prey|bait|bait Irf2 Ube2i MI:0027(cosedimentation)|MI:0018(two hybrid) 16615898,18955028 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_167133|BIOGRID_322303 neutral component|bait neutral component|prey Nfatc2ip Ube2i MI:0096(pull down) 20077568 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_322019 bait prey Egr2 Ube2i MI:0416(fluorescence microscopy)|MI:0416(fluorescence microscopy) 21836637 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact) UniProt_173122|UniProt_173124 bait|prey prey|bait Irf1 Ube2i MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 18955028 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (biogrid)|(biogrid)|(biogrid) BIOGRID_322308|BIOGRID_322304|BIOGRID_322310 prey|bait|prey bait|prey|bait Ube2i Ikzf1 MI:0006(anti bait coimmunoprecipitation) 15767674 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_163993 prey bait Ikzf3 Ube2i MI:0006(anti bait coimmunoprecipitation) 15767674 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_163992 bait prey Fas Ube2i MI:0018(two hybrid)|MI:0004(affinity chromatography technology) 11034606,9257699 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction) (intact)|(biogrid) UniProt_160398|BIOGRID_311718 bait|prey prey|bait Ube2i Uimc1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0027(cosedimentation) 16615898,17698038 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid)|(biogrid)|(intact) BIOGRID_322141|BIOGRID_322139|BIOGRID_322140|UniProt_167133 bait|prey|prey|neutral component prey|bait|bait|neutral component Mdm2 Ube2i MI:0004(affinity chromatography technology) 21183956 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_319562 prey bait Myd88 Ube2i MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_162896 bait prey Sumo1 Ube2i MI:0415(enzymatic study) 15094046 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_325352 bait prey Lmna Ube2i MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation) 16615898,21327095 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(biogrid)|(intact) UniProt_167137|UniProt_167117|UniProt_167133|UniProt_167125|BIOGRID_315861|UniProt_167129 neutral component|neutral component|neutral component|neutral component|bait|neutral component neutral component|neutral component|neutral component|neutral component|prey|neutral component Pou5f1 Ube2i MI:0415(enzymatic study) 17097055 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_315812 prey bait

PPI - HINT Gene A Gene B PMID Method Quality IKZF3 UBE2I 15767674 0018 LC NFATC2IP UBE2I 20077568,20077568 0096,0114 LC PIAS3 UBE2I 12387893 0018 LC FOXL2 UBE2I 22544055 0018 LC JUN UBE2I 10788439 0045 LC EGR2 UBE2I 21836637,21836637 0018,0096 LC REL UBE2I 9223278 0018 LC IRF1 UBE2I 18955028,18955028,18955028 0096,0018,0415 LC TCF3 UBE2I 12200424,9409784 0018,0018 LC GATA1 UBE2I 15173587 0415 LC POU5F1 UBE2I 17097055 0415 LC MYD88 UBE2I 15102471 0018 LC IRF8 UBE2I 18955028 0018 LC MDM2 UBE2I 21183956 0415 LC IRF2 UBE2I 18955028 0018 LC FAS UBE2I 11034606,9257699 0018,0018 LC RANGAP1 UBE2I 11792325,15094046 0415,0415 LC SOX2 UBE2I 17097055 0415 LC CTBP2 UBE2I 16940173,16940173 0018,0096 LC YWHAE UBE2I 16615898 0027 LC UBE2I IKZF1 15767674 0018 LC UBE2I NR2C1 17187077,17187077,17187077 0006,0096,0018 LC UBE2I UIMC1 17698038,17698038,17698038 0096,0004,0018 LC UBE2I NCOR1 16421255 0018 LC UBE2I HIF1A 17981124 0415 LC UBE2I SMAP2 18413247 0018 LC UBE2I MTHFS 22303332 0415 LC UBE2I DACH1 11025202,11025202,11025202 0004,0232,0018 LC UBE2I CASP8AP2 23673342 0415 LC UBE2I SUMO3 20077568 0415 LC UBE2I NFKBIA 9223278 0059 LC NFATC2IP UBE2I 20077568,20077568 0096,0114 LC EGR2 UBE2I 21836637,21836637 0018,0096 LC IRF1 UBE2I 18955028,18955028,18955028 0096,0018,0415 LC TCF3 UBE2I 22354994 0004 LC LMNA UBE2I 21327095 0004 LC CTBP2 UBE2I 16940173,16940173 0018,0096 LC UBE2I NR2C1 17187077,17187077,17187077 0006,0096,0018 LC UBE2I UIMC1 17698038,17698038,17698038 0096,0004,0018 LC UBE2I DACH1 11025202,11025202,11025202 0004,0232,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P63280 P15923 UBE2I TCF3 0.623 9409784 P63280 P23611 UBE2I IRF8 0.309 18955028 P63280 P23906 UBE2I IRF2 0.309 18955028 P63280 P62259 UBE2I YWHAE 0.081 16615898 P63280 O88470 UBE2I FOXL2 0.309 22544055 P63280 P08152 UBE2I EGR2 0.523 21836637 P63280 O09130 UBE2I NFATC2IP 0.523 20077568 P63280 P56546 UBE2I CTBP2 0.523 16940173 P63280 O14524 UBE2I TMEM194A 0.236 26496610 P63280 O14715 UBE2I RGPD8 0.236 26496610 P63280 O15504 UBE2I NUPL2 0.236 26496610 P63280 O95084 UBE2I PRSS23 0.236 26496610 P63280 P18754 UBE2I RCC1 0.236 26496610 P63280 P25446 UBE2I FAS 0.523 11034606,9257699 P63280 P35658 UBE2I NUP214 0.236 26496610 P63280 P46060 UBE2I RANGAP1 0.236 26496610 P63280 P46061 UBE2I RANGAP1 0.523 11792325,15094046 P63280 P49790 UBE2I NUP153 0.236 26496610 P63280 P52948 UBE2I NUP98 0.236 26496610 P63280 P55197 UBE2I MLLT10 0.236 26496610 P63280 P55735 UBE2I SEC13 0.236 26496610 P63280 P57740 UBE2I NUP107 0.236 26496610 P63280 P61956 UBE2I SUMO2 0.236 26496610 P63280 P62826 UBE2I RAN 0.236 26496610 P78406 P63280 RAE1 UBE2I 0.236 26496610 Q12769 P63280 NUP160 UBE2I 0.236 26496610 Q14974 P63280 KPNB1 UBE2I 0.236 26496610 Q53GS7 P63280 GLE1 UBE2I 0.236 26496610 Q5SRE5 P63280 NUP188 UBE2I 0.236 26496610 Q6NUQ4 P63280 TMEM214 UBE2I 0.236 26496610 Q8N1F7 P63280 NUP93 UBE2I 0.236 26496610 Q8NFH3 P63280 NUP43 UBE2I 0.236 26496610 Q8NFH4 P63280 NUP37 UBE2I 0.236 26496610 Q8NFH5 P63280 NUP35 UBE2I 0.236 26496610 Q8WUM0 P63280 NUP133 UBE2I 0.236 26496610 Q92621 P63280 NUP205 UBE2I 0.236 26496610 Q96EE3 P63280 SEH1L UBE2I 0.236 26496610 Q96IX5 P63280 USMG5 UBE2I 0.236 26496610 Q96SK2 P63280 TMEM209 UBE2I 0.236 26496610 Q99567 P63280 NUP88 UBE2I 0.236 26496610 Q9BTX1 P63280 NDC1 UBE2I 0.236 26496610 Q9BW27 P63280 NUP85 UBE2I 0.236 26496610 Q9BXS6 P63280 NUSAP1 UBE2I 0.236 26496610 Q9HC62 P63280 SENP2 UBE2I 0.236 26496610 Q9NRG9 P63280 AAAS UBE2I 0.236 26496610 Q9NXE4 P63280 SMPD4 UBE2I 0.236 26496610 Q9P0U3 P63280 SENP1 UBE2I 0.236 26496610 Q9P209 P63280 CEP72 UBE2I 0.236 26496610 Q9UBE0 P63280 SAE1 UBE2I 0.236 26496610 Q9UBT2 P63280 UBA2 UBE2I 0.236 26496610 Q9UBU9 P63280 NXF1 UBE2I 0.236 26496610 Q9UKX7 P63280 NUP50 UBE2I 0.236 26496610 Q505F1 P63280 NR2C1 UBE2I 0.623 17187077 P63280 P63165 UBE2I SUMO1 0.636 20543865,26496610,17491593 P63280 P49792 UBE2I RANBP2 0.636 26496610,11792325 P63280 P48678 UBE2I LMNA 0.21 21327095 P63280 O54714 UBE2I PIAS3 0.309 12387893 P63280 A8CG34 UBE2I POM121C 0.126 26496610 P63280 O08900 UBE2I IKZF3 0.309 15767674 P63280 E9PF10 UBE2I NUP155 {ECO:0000313|ENSEMBL:ENSP00000422019} 0.126 26496610 P63280 P48432 UBE2I SOX2 0.309 17097055 P63280 P17679 UBE2I GATA1 0.309 15173587 P63280 P06536 UBE2I NR3C1 0.309 11812797 P63280 O75694 UBE2I NUP155 0.126 26496610 P63280 P15806 UBE2I TCF3 0.583 12200424,9409784,22354994 P63280 P11166 UBE2I SLC2A1 0.309 10655495 P63280 P14672 UBE2I SLC2A4 0.309 10655495 P63280 P23497 UBE2I SP100 0.309 11792325 P63280 P20263 UBE2I POU5F1 0.309 17097055 P63280 P22366 UBE2I MYD88 0.183 15102471 P63280 P25445 UBE2I FAS 0.309 10068040 P63280 P23804 UBE2I MDM2 0.309 21183956 P63280 P63166 UBE2I SUMO1 0.309 20077568 Q5U5Q9 P63280 UIMC1 UBE2I 0.623 17698038 Q9D110 P63280 MTHFS UBE2I 0.309 22303332 Q96BH3 P63280 ELSPBP1 UBE2I 0.309 9409784 Q61221 P63280 HIF1A UBE2I 0.309 17981124 Q9H2X6 P63280 HIPK2 UBE2I 0.523 10535925 Q9UKD1 P63280 GMEB2 UBE2I 0.309 11812797 Q9Z172 P63280 SUMO3 UBE2I 0.309 20077568 Q9WUF3 P63280 CASP8AP2 UBE2I 0.309 23673342 Q9Y692 P63280 GMEB1 UBE2I 0.309 11812797 Q03267 P63280 IKZF1 UBE2I 0.309 15767674 P63280 P15314 UBE2I IRF1 0.671 18955028 Q08211 P63280 DHX9 UBE2I 0.309 15312759