PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Rnf5 Ube2e3 19256485 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Tnfaip3 ortho G G G G G Rnf5 Ube2g2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Jkamp ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Tomm40 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Rnf185 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Tmem173 ortho G G G G G G G G G G G G G G G G G G G G G Rnf5 Slc38a2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ubc ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Tgfbr1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2k ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Rnf5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2z ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Derl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2d2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Bcap31 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Dnajc7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2d1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Xrcc3 ortho Rnf5 Yipf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Cftr ortho G G G G G G G G Rnf5 Tuba1c ortho Rnf5 Ube2d2b ortho G Rnf5 Ddx58 ortho Rnf5 Mavs ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2e1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Amfr ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Mpdz ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Cyb561a3 ortho Rnf5 Slc1a2 ortho G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2v1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2u Rnf5 ortho Rnf5 Ube2e2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Sec22a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Adrb2 ortho G G G G G G G G G Rnf5 Abhd16a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Insig2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Atl3 ortho G G G G G G G G G G G G G G G G G Rnf5 Pxn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Cyb561 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Tmem242 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2d3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2n ortho Rnf5 Ube2w ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ube2j1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf5 Ptgdr2 ortho Rnf5 Slc1a1 ortho G G G G G G G G G G G G G G G G G Rnf5 Slc38a7 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P52483 O35445 two hybrid 19256485 direct interaction X 2 O35445 P36897 anti tag coimmunoprecipitation 15761153 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Rnf5 Ube2e3 MI:0096(pull down) 19256485 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_322691 prey bait

PPI - HINT Gene A Gene B PMID Method Quality RNF5 UBE2E3 19256485 0018 LC