PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Wsb1 Tceb2 9869640 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Tceb1 9869640 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Hipk2 18093972 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Csf3r 17001306 biogrid exp, ortho G G G G G G G Wsb1 Gsk3b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Dcun1d1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Cftr ortho G G G G G G G G Wsb1 Smad1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Tgfbr1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Rnf7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Dio2 ortho G G G G G G G G G G G G G G G Wsb1 Ube2d3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Cul5 ortho Wsb1 Cul4a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P62869 O54927 pull down 9869640 direct interaction X 2 Q15370-2 O54927 affinity chromatography technology 15601820 physical association X 2 O54927 Q9UBF6-2 affinity chromatography technology 15601820 physical association X 2 P83940 O54927 pull down 9869640 direct interaction X 2 P36897 O54927 affinity chromatography technology 15761153 physical association X 2 A0A024R730 O54927 affinity chromatography technology 17110338 physical association X 2 Q13617 O54927 pull down 11384984 direct interaction X 2 O54927 two hybrid 17001306 direct interaction X 2 Q15369-2 O54927 affinity chromatography technology 15601820 physical association X 2 Q93034 O54927 affinity chromatography technology 15601820 physical association X 2 Q93034 O54927 pull down 11384984 direct interaction X 2 O54927 anti tag coimmunoprecipitation 15601820 association C 5 O54927 anti tag coimmunoprecipitation 15601820 association C 5 Q9QZR5 O54927 two hybrid 18093972 physical association X 2 Q9QZR5 O54927 two hybrid 18093972 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Wsb1 Hipk2 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 18093972 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_168836|UniProt_168832 prey|prey bait|bait Wsb1 Tceb1 MI:0004(affinity chromatography technology) 9869640 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_315422 bait prey Wsb1 Tceb2 MI:0004(affinity chromatography technology) 9869640 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_315421 bait prey Wsb1 Csf3r MI:0004(affinity chromatography technology) 17001306 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_319778 prey bait

PPI - HINT Gene A Gene B PMID Method Quality WSB1 CSF3R 17001306 0018 LC WSB1 HIPK2 18093972 0018 LC WSB1 TCEB2 9869640 0096 LC WSB1 TCEB1 9869640 0096 LC