PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Znf106 Fyn 9507006 biogrid,i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Raver1 15102471 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G Diaph1 Fyn 18194650 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rbfox2 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ptpn18 11158295 mint exp G G G G G G G G G G G G G G G G G G G G G G G Csf1r Fyn 15297464 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dynlt1 15102471 i2d,mint,intact exp Fyn Hcls1 10713104 intact exp G G G G G G G G Protein Rasa1 Fyn 8395016 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ywhae 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Uck2 15102471 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf9 Fyn 24036998 innatedb exp G G G G G G G G G Klrk1 Fyn 24036998 innatedb exp G G G G G G G Fyn Clnk 12681493 mint,intact exp Fyn Ywhab 16635246 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Fmn1 8605874 biogrid exp G Fyn Enah 8861907 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eno1 Fyn 18854310 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Son i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd247 Fyn i2d exp Fyn Sh2d1c 16425036 biogrid exp Fyn Sh3bp1 i2d exp G G G G G G G G G G G G Fyn Fyn i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mapt Fyn i2d exp, ortho G G G G G G G G G G G G G G G Fyn Slamf1 12545173,16847311,11477403 mint,intact exp, ortho G G G G G G Pik3r1 Fyn 24036998,9115297,8395016 innatedb,biogrid,i2d,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Nphs1 i2d exp, ortho G G G G G Fyn Bcar1 15102471 i2d,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Fyn 19966925 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Add2 16765915 mint,intact exp, ortho G G G G G G G G G Fyn Sphk2 16316995 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdgfrb Fyn 7730365 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptprf Fyn 18854310 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctla4 Fyn 9712716 i2d,mint,intact exp, ortho G G Ptk2 Fyn 15102471 i2d,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Khdrbs1 10844001,7799925,15102471 biogrid,mint,intact,dip exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Il7r Fyn i2d exp, ortho G G G G G G G G G Fyn Arhgap33 16777849 intact exp, ortho Fyn Plcg2 8395016 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Grb2 7499280 innatedb exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Efs i2d exp, ortho G G G G G G G G G G G G G G G G G G G G Cbl Fyn 9210408,19734451,8551236,9890970,8635998 biogrid,i2d,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sh2d1a Fyn 12545173,16847311 mint,intact exp, ortho G G Vav1 Fyn i2d exp, ortho G G G G G Fyn Tom1l1 i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G Fyb Fyn 12681493 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G Fyn Dcc i2d exp, ortho G G G G Fyn Syk 7797565 innatedb exp, ortho G G G G G G G G G G G G G G G G G Fyn Hnrnpk i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cdk5 12372285 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Epha4 8622893 i2d,dip exp, ortho G G G G G G G G Fyn Jak2 7499280 innatedb exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptpra Fyn 9535845,18948260 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Med28 16899217 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Grin2b i2d exp, ortho G G G G G Fyn Ptk2b 15102471 i2d,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Skap2 12681493 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sos1 i2d exp, ortho G G G G G G G G G Fyn Pxn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dok4 ortho G G G G G G G G G G G G G G Fyn Skap1 ortho Fyn Psmc4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gpr63 ortho Cd2 Fyn ortho G G G G G G Fyn Casp3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rras Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Stk17b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plaur Fyn ortho G G G G G G G G G G G G G G G G G G G Fyn Myo18a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Tulp4 ortho Fyn Mybbp1a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Hras ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncam1 Fyn ortho G G G G G G G G G G G G G G G G G Birc6 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nedd9 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G Fyn Plcg1 ortho Xrcc6 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Casp8 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G Fyn Prickle3 ortho Fyn Cacna1f ortho G G G G Fyn Yes1 ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Anln ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Grap ortho Fyn Kcna4 ortho G G G G G Fyn Flot2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Shroom2 Fyn ortho Ctnnd1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Galr3 Fyn ortho Fgr Fyn ortho G G G G G G G G G G G G G Protein Nckap5 Fyn ortho Fyn Frk ortho G G G G G G G G G G G G G G G G Fyn Dnase1l2 ortho G G G G G G G Fyn Aire ortho Fyn Gcfc2 ortho Hist1h2bm Fyn ortho Tec Fyn ortho G G G G G G G G G G G G G G G G G G G G G Irs1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltbp2 Fyn ortho G G G G G G G G G G G Fyn Jup ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sec61a1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cyp4f3 ortho G G G G G G G G Itpr1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sp1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cd244 ortho G G G Fyn Limk1 ortho G G G G G G G G G G G G G G Fyn Slc25a41 ortho Cxcl13 Fyn ortho G G G G G G G G G G G G G Fyn Dok3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Cenpa Fyn ortho G G G G G G G G G G G G G G G G G G G Itgb4 Fyn ortho G G G G G G G G G G Tnk2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Protein Arhgef11, Rho guanine nucleotide exchange factor (GEF) 11 ortho Tsks Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Shank3 ortho G G G G G G G G G G G G G G G G G G G G G G G Fyn Cnn3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Npvf ortho G Fyn Vav2 ortho G Fyn Rps6ka4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dlgap2 ortho Grin1 Fyn ortho G G G G G G G G Kit Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Lck Fyn ortho G G G G G G G G G G G G G G Cntn1 Fyn ortho G G G G G G G G G G G G Nr5a1 Fyn ortho G G G G G G Ptprz1 Fyn ortho G G G G G G G G G G G G G G G G G Lyn Fyn ortho Ptpn11 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Srpk1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Stip1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ltbr ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sema5a ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Znfx1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gnb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fgfr2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gucy2e ortho Fyn Ddx41 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Txk ortho G G Fyn Was ortho G G G G G G G G G Fyn Mcam ortho G G G G G G G G G G G G G G G G G G G G Fyn Psmd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rps6ka2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sf3b4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sdc3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prdx6 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tuba1b Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dok1 ortho G G G G G G G G G G G G G G G G G G G G Protein Mki67 Fyn ortho G G G G G G G G G G G G G G G G G G G G G Ikbkg Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkch Fyn ortho G G G G G G G G G G G G G G G G G Rpl35a Fyn ortho Fyn Uhrf2 ortho Fyn Atp5b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Arhgap32 ortho Fyn E2f7 ortho Fyn Vps13a ortho Fyn Cct7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Asap2 ortho Il3ra Fyn ortho G G G Fyn Akap6 ortho Fyn Suv39h2 ortho G G G G Fyn Runx3 ortho Adam15 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Stk4 ortho G G G G G G G Flot1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pkd1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Pdip Fyn ortho Fyn Dnm3 ortho G G G G G G G G G G G G G G G Fyn Trpc6 ortho Snx3 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prx Fyn ortho G G G G G G G G Fyn Cd36 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Map2 Fyn ortho Fyn Mapk11 ortho G G G G G G G G Fyn Brd8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Slc16a1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gns ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ythdc1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Map4k5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Synj2 ortho G G G G G G G G G G G G G G G G G G G Fyn Gstz1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Tuba4a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Hcrtr2 ortho Fyn Ccr10 ortho Fyn Bcl3 ortho G G G G G G G G G G G G G G G G G G Fyn Ptpre ortho G G G G G G G G G G G G G G G G G G G G G G Lat Fyn ortho G G G G G G G G G Fyn Ccnl2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Wasf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cct5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cd2ap ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Asap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sit1 ortho G G G Cdh1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Snx17 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Bcr ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rps15a ortho Fyn Baz2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Jak1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Extl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Slc25a5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Crk ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gab3 ortho G G G G Spn Fyn ortho G G G G G Fyn Pms2 ortho G G G G G G G G G G G G G G G G G G G G G G G Fyn Shc1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cse1l ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf1a Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dlgap1 ortho Hsp90ab1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cdcp1 ortho G G G G G G G G G G G G G G G G G G Fyn Rpp38 ortho Fyn Dock3 ortho Flt1 Fyn ortho G G G G G G G G G G G G G G G G G G Fyn Prlr ortho G G G G G G G G G G G G G G G G G G Cd4 Fyn ortho G G Fyn Tyro3 ortho G G G G G G G G G G G G G Fyn Csk ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Abce1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nr3c1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rin3 ortho Tnnt1 Fyn ortho G G G G G G G G G Fyn Atad3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sh3bp5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dlg4 ortho G G G G G G G G G G Fyn Protein Slc24a1, Solute carrier family 24 (Sodium/potassium/calcium exchanger), member 1 ortho G Fyn Ctnnb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rims1 ortho Fyn Cav1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cd226 ortho Fyn Scarf2 ortho Tmem185a Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Htr6 ortho Fcgr2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Orc1 ortho G G G G Hcn2 Fyn ortho G G G G G G G G G Fyn Pdss2 ortho F2rl2 Fyn ortho G G G G G G G G G Fyn Map4k4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Nfs1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd5 Fyn ortho G G G Fyn Oxsr1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Tsnax ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Met Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Erbb2 ortho G G G G G G G G G G G G Hoxb5 Fyn ortho G G G G G G G Fyn Rps27a ortho Fyn Brca2 ortho G G G G G G G G G G G G G G G G G G G G G Fyn Ptp4a3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Xrcc1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd8a Fyn ortho G G G G G G Fyn Rpl18a ortho Fyn Pax7 ortho G Fyn Nbea ortho G G G G G G G G G G G G G G G G G G G G G G G G Srpk2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Blk Fyn ortho G G G G G Fyn Tmem132a ortho G G G G G G G G G G G G G G G G G G G G G G G Fyn Lcp2 ortho G G G G G G G G G G G G G G Dnm1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Tulp1 ortho G G G Ankyrin repeat domain 12, isoform CRA_a, Protein Ankrd12 Fyn ortho Cntnap1 Fyn ortho Suv39h1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sh2b2 ortho G G G G G G Fyn Nfasc ortho Fyn Wnk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Prpsap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sh3kbp1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Isg20l2 ortho Fyn Stat3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Raf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Trpv4 ortho G G G Fyn Pak2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nmt1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dag1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Pold1 ortho G G G G G G G G G G G G G G G G G G G G G Fyn Tyk2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Protein Rapgef1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snca Fyn ortho G G G G G G G G G G G G G G G G Cma1 Fyn ortho G G G G G G Btk Fyn ortho G G G G G Fyn Nck1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Hdac6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Abl1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Eif2s3x ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ms4a1 Fyn ortho G G G G G G G G G G Fyn Lrba ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Traip ortho G G G G G G G G Tcap Fyn ortho G G G G G G G G G G G Mos Fyn ortho Fyn Abi1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cckbr ortho G G G G Fyn Sdhb ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Map4k1 ortho G G G G G G Bromodomain and PHD finger containing, 3, Protein Brpf3 Fyn ortho Fyn Cblc ortho G G G G G G G G G G G G G G Fyn Trat1 ortho G G Fyn Abl2 ortho G G G G G G G G G G G G Cd44 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Kcna2 ortho G G G G G Fyn G3bp1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Heterogeneous nuclear ribonucleoprotein R, Protein Hnrnpr ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Xpo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Itk ortho G G G Prkce Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gcn1l1 ortho Fyn Nkx2-1 ortho G Xrcc5 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rpl10 ortho Hexa Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ddx1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd3g Fyn ortho G G G G G G G G G Fyn Erh ortho Fyn Flnc ortho G G G G G G G G G G G Fyn Ubr5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Flna ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Wbp11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ifitm3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dlgap4 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cd300lb ortho Fyn UPF0488 protein C8orf33 homolog ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd79b Fyn ortho G G G G G G G G G G Fcgr3 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Pik3r3 ortho Fyn Pld2 ortho G G G G G G G G G G G G G G G G G G G G G G G Fyn Wnk2 ortho G G G G G G G G G G G G G G G G G G G G G Fyn Cast ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Osteoregulin, Protein Mepe ortho G Fyn Mapre1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fn1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Kdm1a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctnnd2 Fyn ortho G G G G G G G G Epha8 Fyn ortho Fyn Tnik ortho Cd48 Fyn ortho G G G G G G G G G G G G G G Fyn Dcbld2 ortho G G G G G G G G G G G G G G G G G Fyn Tek ortho G G G G G G G G G G G G G G G G G G G G G G G G Fyn Grb10 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Evl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Unc119 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Socs1 Fyn ortho Fyn Pecam1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Stat1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cdkl5 ortho Fyn Ick ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd19 Fyn ortho G G G G G Fyn Fanca ortho G G G G G G G G G G G G G G G G G G G G Mag Fyn ortho G G G G G G G G Fyn Wipf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sh3bp2 ortho G G G G G G G G G G G G G G Fyn Crkl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cct3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Itch ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hcn4 Fyn ortho Tnf Fyn ortho Fyn Ephb3 ortho G G G G G G G G G G Fyn Tdrd1 ortho G Fyn Dlx4 ortho G Fyn Gad1 ortho G G G G G G G G Foxf2 Fyn ortho G G G Fyn Ptpn4 ortho G G Fyn Snrpd1 ortho Fyn Sfxn4 ortho G G G G G G G G G G Pax3 Fyn ortho G G G G Cd3d Fyn ortho G G G G G G G G G Dhx9 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Asb16 ortho G G Fyn Complement component 6, Protein C6 ortho G G G G G Fyn Atxn1 ortho Fyn Havcr2 ortho G G G Fyn Ppp1r12a ortho Fyn UPF0415 protein C7orf25 homolog ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Pink1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G Fyn Gng2 ortho G G G G G G G G G G G G G G Fyn Prpf8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Prkcz ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Prkdc ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cntfr Fyn ortho G G G G G G G G G G Pik3r2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccdc8 Fyn ortho Fyn Zap70 ortho G G G G G G G G G G G G G G Fyn Nckipsd ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fasn Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ephb2 ortho G G G G G G G G G G G G Pde4a Fyn ortho G G G G G G G G G G G G G G Fyn Pag1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Eps15 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc27 Fyn ortho G G G G G G Fyn Rps20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Snx8 ortho Fyn Rps6ka5 ortho Fyn Celsr3 ortho G G G G G G G G Fyn Sos2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dapk2 ortho G G G G G G G G G G G G G G G G G G G G G G Fyn Snrpd3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fcer2 Fyn ortho G G G G G G G Fyn Slc25a3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Sema7a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Myh9 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dock1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Mapk13 ortho G G G G G G G G G G G G G G G G G Fyn Slc25a11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Fnbp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snx12 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rps11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rp1l1 ortho Fyn Kcna5 ortho G G G G G G G G G G G G Fyn Dusp15 ortho G G Fyn Prkcq ortho G G G G G G G G G G G G G G G G Kmt2b Fyn ortho Fyn Rims2 ortho G G G G G G G G G G Gp6 Fyn ortho Fyn Gtf3a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cdc37 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tcp1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ptprd ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Nek8 ortho G G G G G Fyn Traf6 ortho G G G G G G G G G G G G G G G G G G G G Fyn Dlgap3 ortho Cd79a Fyn ortho G G G G G G G G G G Hoxc8 Fyn ortho G G G G G G G G G G Fyn Cblb ortho Il2rb Fyn ortho G G G G G G Fyn Dnaja1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cckar Fyn ortho G G G G G Fyn Kctd5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Rtn4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Cltc ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gpr45 ortho G Fyn Cenpv ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsp90aa1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ppp1r12b ortho Fyn Prmt6 ortho G G G G G G G G G Fyn Cnn1 ortho G G G G G G G G G G G G G Fyn Cnr1 ortho G G G G G Fas Fyn ortho G G G G G G G G G G G G G G G G G Fyn Mink1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Faslg ortho G Fyn Dab2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Pdcd6ip ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Src Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ckap5 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Il1b Fyn ortho G G G G G G G G G G Mknk1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Wasf1 ortho G G G G G G G G G G G G G G G G G Fyn Stk38 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Fam110a ortho G G G G G G G G G G Fyn Ndfip2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Chaf1a ortho Fyn Gabbr1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Nelfb ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkcd Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Acp1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Dkkl1 ortho G G G Med14 Fyn ortho G G G G G Hck Fyn ortho G G G G G G G G G G G G G G G G G G G G Thy1 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Itgb2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G Fyn Trim39 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Epb41l3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rdx Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk2 Fyn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd247 Fyn ortho G G G Fyn Kpnb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Ptpn5 ortho G G G G G Fyn Chrna7 ortho G Fyn Sphk1 ortho G G G G G G G G G G G G G G Fyn Atp1a1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Map3k12 ortho G G G G G G G G G G G G G G Grin2a Fyn ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P39688 anti tag coimmunoprecipitation 11477403 association C 3 P39688 coimmunoprecipitation 15539156 association C 3 P39688 Q9JLQ0 coimmunoprecipitation 16628251 association X 2 P39688 cosedimentation through density gradient 16635246 colocalization C 608 P39688 anti bait coimmunoprecipitation 16847311 association C 3 P39688 pull down 16847311 association C 3 P39688 pull down 16847311 association C 3 P18052 P39688 cosedimentation through density gradient 18948260 colocalization X 2 P18052 P39688 anti bait coimmunoprecipitation 9535845 physical association X 2 P34152 P39688 two hybrid 15102471 physical association X 2 Q99PM9 P39688 two hybrid 15102471 physical association X 2 P22682 P39688 anti bait coimmunoprecipitation 9890970 physical association X 2 P39688 P49615 anti tag coimmunoprecipitation 12372285 physical association X 2 P39688 Q61140 two hybrid 15102471 physical association X 2 P39688 Q9QYB8 pull down 16765915 association X 2 P39688 P07333 pull down 7730365 association X 2 P39688 Q8CIH5 pull down 8395016 physical association X 2 P39688 P35570 pull down 8631859 association X 2 P39688 P35570 pull down 8631859 association X 2 P39688 P35570 anti bait coimmunoprecipitation 8631859 association X 2 P39688 P35570 anti bait coimmunoprecipitation 8631859 association X 2 P39688 P18433 anti tag coimmunoprecipitation 9535845 physical association X 2 P39688 P18433 anti bait coimmunoprecipitation 9535845 physical association X 2 P39688 anti tag coimmunoprecipitation 12372285 association C 3 P39688 anti tag coimmunoprecipitation 12372285 association C 3 P26450 P39688 pull down 8395016 physical association X 2 Q9H204 P39688 pull down 16899217 physical association X 2 P49446 P39688 genetic interference 14980517 genetic interaction X 2 O35601 P39688 pull down 12681493 physical association X 2 O14522 P39688 anti bait coimmunoprecipitation 19816407 physical association X 2 Q9QZE2 P39688 anti bait coimmunoprecipitation 12681493 physical association X 2 P39688 P49710 anti bait coimmunoprecipitation 10713104 physical association X 2 P39688 Q9NZA1 pull down 10930415 association X 2 P39688 Q9QUM4 pull down 11477403 association X 2 P39688 Q9QUM4 anti bait coimmunoprecipitation 11477403 physical association X 2 P39688 Q9QUM4 anti bait coimmunoprecipitation 11477403 physical association X 2 P39688 Q9QUM4 pull down 11477403 direct interaction X 2 P39688 Q9QUM4 pull down 11477403 direct interaction X 2 P39688 Q9QUM4 pull down 11477403 association X 2 P39688 O75051 anti tag coimmunoprecipitation 12372285 physical association X 2 P39688 Q9QUM4 pull down 12545173 physical association X 2 P39688 O88890 pull down 12545173 physical association X 2 P39688 Q9QUM4 anti bait coimmunoprecipitation 12545173 physical association X 2 P39688 Q9QUM4 anti bait coimmunoprecipitation 12545173 physical association X 2 P39688 Q9QUM4 anti tag coimmunoprecipitation 12545173 physical association X 2 P39688 Q9QUM4 pull down 12545173 physical association X 2 P39688 O88890 pull down 12545173 physical association X 2 P39688 P51807 two hybrid 15102471 physical association X 2 P39688 Q8C2G0 two hybrid 15102471 physical association X 2 P39688 P51807 two hybrid 15102471 physical association X 2 P39688 P51807 two hybrid 15102471 physical association X 2 P39688 Q80YF9 anti bait coimmunoprecipitation 16777849 physical association X 2 P39688 Q9QUM4 pull down 16847311 physical association X 2 P39688 Q920D3 anti bait coimmunoprecipitation 16899217 physical association X 2 P39688 A0A024R9Y1 pull down 21692989 physical association X 2 P39688 P05622 pull down 7730365 association X 2 P39688 P05622 pull down 7730365 association X 2 P39688 P05622 pull down 7730365 association X 2 P39688 P09793 coimmunoprecipitation 9712716 association X 2 P39688 P09793 coimmunoprecipitation 9712716 association X 2 P39688 P22681 far western blotting 9890970 direct interaction X 2 P39688 P22681 pull down 9890970 association X 2 P39688 P22681 pull down 9890970 physical association X 2 Q3UND0 P39688 pull down 12681493 physical association X 2 Q91YX7 P39688 pull down 8395016 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q60749 P39688 two hybrid 15102471 physical association X 2 Q9CW46 P39688 two hybrid 15102471 physical association X 2 Q9JIA7 P39688 anti bait coimmunoprecipitation 16316995 direct interaction X 2 Q9JIA7 P39688 anti bait coimmunoprecipitation 16316995 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Fyn Raver1 MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_164980 bait prey Pik3r1 Fyn MI:0401(biochemical)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 8395016,9115297 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact) BIOGRID_322547|MINT_71824|UniProt_177301 prey|prey|prey bait|bait|bait Fyn Ptpre MI:0007(anti tag coimmunoprecipitation) 14980517 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0208(genetic interaction) (intact) UniProt_163700 neutral component neutral component Diaph1 Fyn MI:0027(cosedimentation)|MI:0004(affinity chromatography technology) 16615898,18194650 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association) (intact)|(biogrid) UniProt_167131|BIOGRID_323149 neutral component|prey neutral component|bait Fyn Dynlt1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_165024|UniProt_164994|UniProt_165023 bait|bait|bait prey|prey|prey Fyn Sphk2 MI:0027(cosedimentation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 16316995,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0407(direct interaction) (intact)|(intact)|(intact) UniProt_167131|UniProt_166117|UniProt_166116 neutral component|bait|bait neutral component|prey|prey Ptk2 Fyn MI:0027(cosedimentation)|MI:0018(two hybrid) 15102471,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact) UniProt_167131|UniProt_164995 neutral component|prey neutral component|bait Fyb Fyn MI:0019(coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 12681493 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_163515|MINT_59903 prey|prey bait|bait Fyn Hcls1 MI:0018(two hybrid) 10713104 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_160791 bait prey Fyn Cdk5 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 12372285 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_162024|UniProt_69860 bait|bait prey|prey Fyn Plcg2 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 8395016 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_177303|MINT_71826 bait|bait prey|prey Ptpra Fyn MI:0027(cosedimentation)|MI:0029(cosedimentation through density gradient)|MI:0007(anti tag coimmunoprecipitation) 16615898,18948260,9535845 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_167131|UniProt_169185|UniProt_177783 neutral component|unspecified role|prey neutral component|unspecified role|bait Fyn Ptprf MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0029(cosedimentation through density gradient) 16635246,18854310 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid)|(intact) BIOGRID_320182|BIOGRID_320181|UniProt_166352 prey|prey|neutral component bait|bait|neutral component Fyn Rasa1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 8395016 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_177302|MINT_71825 bait|bait prey|prey Zfp106 Fyn MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 9507006 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_324542|BIOGRID_324541 prey|bait bait|prey Fyn Bcar1 MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_164972 bait prey Ubc Fyn MI:0004(affinity chromatography technology) 19966925 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_316165 prey bait Fyn Khdrbs1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0415(enzymatic study)|MI:0019(coimmunoprecipitation)|MI:0018(two hybrid) 10844001,15102471,7799925 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|MI:0465(dip)|(intact) UniProt_164968|UniProt_164969|UniProt_164987|UniProt_164988|UniProt_164989|UniProt_164964|UniProt_164977|UniProt_164965|UniProt_164966|UniProt_164967|UniProt_164976|UniProt_165021|BIOGRID_322112|DIP_175|UniProt_164990 bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|bait|-|bait prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|prey|-|prey Eno1 Fyn MI:0027(cosedimentation)|MI:0029(cosedimentation through density gradient)|MI:0415(enzymatic study) 16615898,16635246,18854310 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0407(direct interaction) (intact)|(intact)|(biogrid) UniProt_167131|UniProt_166352|BIOGRID_320180 neutral component|neutral component|prey neutral component|neutral component|bait Fyn Fmn1 MI:0096(pull down) 8605874 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_329114 prey bait Fyn Med28 MI:0018(two hybrid) 16899217 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_166329 prey bait Fyn Epha4 MI:0401(biochemical) 8622893 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) MI:0465(dip) DIP_129 - - Fyn Enah MI:0096(pull down) 8861907 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_328987 prey bait Fyn Ptk2b MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_164971 bait prey Fyn Skap2 MI:0019(coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 12681493 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_163516|MINT_59904 bait|bait prey|prey Sh2d1a Fyn MI:0096(pull down)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 12545173,16847311 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association) (intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact) UniProt_163582|UniProt_163581|MINT_59695|MINT_59697|UniProt_167010 prey|bait|bait|prey|prey bait|prey|prey|bait|bait Pdgfrb Fyn MI:0027(cosedimentation)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down) 16615898,7730365 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) (intact)|MI:0471(mint)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|(intact) UniProt_167131|MINT_79699|UniProt_133741|UniProt_133740|UniProt_133742|MINT_80253|MINT_79782|UniProt_177370|UniProt_177369|UniProt_177368 neutral component|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role neutral component|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role|unspecified role Fyn Clnk MI:0019(coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 12681493 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|MI:0471(mint) UniProt_163519|MINT_59900 prey|prey bait|bait Csf1r Fyn MI:0004(affinity chromatography technology) 15297464 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322527 bait prey Fyn Add2 MI:0029(cosedimentation through density gradient)|MI:0096(pull down)|MI:0096(pull down) 16635246,16765915 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0914(association)|MI:0914(association) (intact)|MI:0471(mint)|(intact) UniProt_166352|MINT_80021|UniProt_167217 neutral component|unspecified role|unspecified role neutral component|unspecified role|unspecified role Fyn Arhgap33 MI:0018(two hybrid) 16777849 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_166611 prey bait Fyn Slamf1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation)|MI:0096(pull down)|MI:0096(pull down)|MI:0019(coimmunoprecipitation)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0096(pull down)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 10,11477403,12545173,16847311 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|(intact)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|MI:0471(mint)|(intact) MINT_59691|MINT_59690|MINT_59893|MINT_59894|UniProt_167011|UniProt_161817|MINT_79833|UniProt_163584|UniProt_161816|UniProt_163583|UniProt_163577|MINT_79530|UniProt_163585|MINT_59698|UniProt_161821|MINT_59890|MINT_70997|UniProt_161820|MINT_59891|MINT_59694|UniProt_161823|MINT_59696|UniProt_163580|UniProt_161824|UniProt_167010|UniProt_167009|MINT_70998|MINT_70995|MINT_70996|UniProt_167012 bait|prey|prey|prey|bait|prey|unspecified role|bait|prey|prey|bait|unspecified role|prey|prey|prey|prey|bait|prey|prey|bait|unspecified role|bait|bait|unspecified role|bait|prey|bait|prey|bait|bait prey|bait|bait|bait|prey|bait|unspecified role|prey|bait|bait|prey|unspecified role|bait|bait|bait|bait|prey|bait|bait|prey|unspecified role|prey|prey|unspecified role|prey|bait|prey|bait|prey|prey Ctla4 Fyn MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation)|MI:0019(coimmunoprecipitation) 9712716 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0914(association) MI:0471(mint)|MI:0471(mint)|(intact)|(intact) MINT_80060|MINT_79605|UniProt_177622|UniProt_177621 unspecified role|unspecified role|unspecified role|unspecified role unspecified role|unspecified role|unspecified role|unspecified role Cbl Fyn MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0096(pull down) 19734451,8551236,8635998,9210408,9890970 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid)|(intact)|(biogrid)|(biogrid)|(biogrid)|MI:0471(mint) BIOGRID_321267|BIOGRID_328556|BIOGRID_322369|BIOGRID_321269|UniProt_177582|BIOGRID_329489|BIOGRID_318849|BIOGRID_322370|MINT_71838 prey|prey|bait|bait|bait|prey|bait|prey|bait bait|bait|prey|prey|prey|bait|prey|bait|prey Fyn Uck2 MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_164996 bait prey Fyn Sh2d1b2 MI:0004(affinity chromatography technology) 16425036 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_329026 bait prey

PPI - HINT Gene A Gene B PMID Method Quality GPATCH8 FYN 9185665 0018 LC PTPRF FYN 18854310,18854310 0004,0415 LC ZNF106 FYN 9507006,9507006 0415,0004 LC CTLA4 FYN 9712716 0019 LC ENO1 FYN 18854310 0415 LC PTPRA FYN 18948260 0029 LC CBL FYN 9890970,9890970,8995358,9890970,8995358,9890970 0019,0006,0004,0004,0019,0045 LC VAV1 FYN 9822663 0019 LC CD247 FYN 1454062,1448076 0019,0019 LC PTK2 FYN 15494732,15102471 0019,0018 LC FYN FYN 15735648 0045 LC FYN ZAP70 8568236,8568236 0004,0019 LC FYN SYK 7797565 0059 LC FYN DYNLT1 15102471,9185665 0018,0018 LC FYN HNRNPK 9185665 0018 LC FYN YWHAE 16615898 0027 LC FYN DCC 15494734 0019 LC FYN GRIN2B 11024032 0045 LC FYN EPHA4 8622893,8622893,8622893 0401,0004,0107 LC FYN KHDRBS1 7799925,10844001,7799925,15102471,7799925 0004,0415,0018,0018,0019 LC FYN BCAR1 10739664,15102471 0018,0018 LC FYN EFS 8570184,8570184,8570184 0045,0019,0004 LC FYN UCK2 15102471 0018 LC FYN YWHAB 16635246 0029 LC FYN RAVER1 15102471 0018 LC FYN CD2AP 16628251 0019 LC FYN PTK2B 9774338,15102471 0019,0018 LC FYN SON 9185665 0018 LC FYN NPHS1 15634346,15634346 0045,0004 LC PTPRF FYN 18854310,18854310 0004,0415 LC RASA1 FYN 8395016 0096 LC DIAPH1 FYN 18194650 0004 LC FYB FYN 12681493 0096 LC ZNF106 FYN 9507006,9507006 0415,0004 LC SH2D1A FYN 12545173,16847311 0096,0096 LC PDGFRB FYN 7730365 0096 LC CSF1R FYN 15297464 0004 LC UBC FYN 19966925 0004 LC PTPRA FYN 9535845 0006 LC CBL FYN 9890970,9890970,8995358,8635998,9890970,8551236,8995358,7782294,9890970,19734451,9210408 0019,0006,0004,0004,0004,0004,0019,0004,0045,0004,0004 LC PIK3R1 FYN 9115297,8395016,8128248 0004,0096,0004 LC KDR FYN 16966330 0004 LC FYN ZAP70 8568236,8568236 0004,0019 LC FYN CDK5 12372285 0007 LC FYN HCLS1 10713104 0006 LC FYN SH3BP1 8402898 0004 LC FYN EPHA4 8622893,8622893,8622893 0401,0004,0107 LC FYN ENAH 8861907 0096 LC FYN FMN1 8605874 0096 LC FYN SKAP2 12681493 0096 LC FYN SH2D1B2 16425036 0004 LC FYN GRB2 7499280 0007 LC FYN KHDRBS1 7799925,7799925,7799925,10077576 0004,0018,0019,0096 LC FYN SOS1 8402898 0004 LC FYN EFS 8570184,8570184,8570184 0045,0019,0004 LC FYN ARHGAP33 16777849 0006 LC FYN PLCG2 8395016 0096 LC FYN MED28 16899217 0006 LC FYN NCK1 16966330 0004 LC FYN SPHK2 16316995 0006 LC FYN TMEM47 21881001,21881001 0006,0663 LC FYN SLAMF1 16847311,11477403,12545173,16847311,11477403,12545173,12545173 0006,0096,0096,0096,0006,0007,0006 LC FYN ADD2 16765915 0096 LC FYN CLNK 12681493 0006 LC FYN NPHS1 15634346,15634346 0045,0004 LC FYN KHDRBS2 10077576 0096 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q60787 P39688 LCP2 FYN 0.126 24584089 Q61140 P39688 BCAR1 FYN 0.183 15102471 Q05860 P39688 FMN1 FYN 0.309 8605874 P62259 P39688 YWHAE FYN 0.081 16615898 Q8CIH5 P39688 PLCG2 FYN 0.21 8395016 P39688 O54957 FYN LAT 0.126 24584089 Q9H204 P39688 MED28 FYN 0.21 16899217 Q9NZA1 P39688 CLIC5 FYN 0.21 10930415 P39688 P09793 FYN CTLA4 0.21 9712716 P39688 O35601 FYN FYB 0.21 12681493 Q8C2G0 P39688 PTK2B FYN 0.183 15102471 P39688 P09581 FYN CSF1R 0.21 15297464 P39688 P07333 FYN CSF1R 0.21 7730365 P39688 P18052 FYN PTPRA 0.309 18948260,9535845 Q3U1F9 P39688 PAG1 FYN 0.236 26512138 P39688 A2A8L5 FYN PTPRF 0.454 18854310 Q14332 P39688 FZD2 FYN 0.454 25417160 Q03137 P39688 EPHA4 FYN 0.332 8622893 P39688 P26450 FYN PIK3R1 0.376 9115297,8395016 P39688 P22681 FYN CBL 0.569 9890970 P39688 P22682 FYN CBL 0.867 8635998,27474268,9210408,8551236,9890970,19734451 Q91YX7 P39688 RASA1 FYN 0.21 8395016 Q920D3 P39688 MED28 FYN 0.21 16899217 Q99PM9 P39688 UCK2 FYN 0.183 15102471 Q9CQV8 P39688 YWHAB FYN 0.081 16635246 Q9CW46 P39688 RAVER1 FYN 0.183 15102471 P39688 O08808 FYN DIAPH1 0.21 18194650 P39688 O88466 FYN ZNF106 0.454 9507006 P39688 O88890 FYN SH2D1A 0.376 16847311,12545173 P39688 P05622 FYN PDGFRB 0.376 7730365 P39688 P0CG50 FYN UBC 0.21 19966925 P39688 P10636 FYN MAPT 0.21 21692989 P39688 P17182 FYN ENO1 0.309 18854310 P39688 P18433 FYN PTPRA 0.376 9535845 P39688 P35570 FYN IRS1 0.507 8631859 P40763 P39688 STAT3 FYN 0.21 25417160 P49710 P39688 HCLS1 FYN 0.21 10713104 Q03405 P39688 PLAUR FYN 0.033 9417082 Q45HK4 P39688 SH2D1B2 FYN 0.21 16425036 Q60749 P39688 KHDRBS1 FYN 0.49 15102471,7799925,10844001 Q80YF9 P39688 ARHGAP33 FYN 0.21 16777849 Q99M51 P39688 NCK1 FYN 0.21 16966330 Q9JIA7 P39688 SPHK2 FYN 0.454 16316995 Q9QUM4 P39688 SLAMF1 FYN 0.895 12545173,16847311,11477403 Q9QYB8 P39688 ADD2 FYN 0.21 16765915 P39688 P34152 FYN PTK2 0.183 15102471 Q9QZE2 P39688 CLNK FYN 0.21 12681493 P51807 P39688 DYNLT1 FYN 0.183 15102471 Q03173 P39688 ENAH FYN 0.309 8861907 Q3UND0 P39688 SKAP2 FYN 0.21 12681493 P39688 O14522 FYN PTPRT 0.21 19816407