iUUCD 2.0 - integrated annotations for ubiquitin and ubiquitin-like conjugation database

PPI - IID
Symbol 1	Symbol 2	PMID	DBs	Evidence Type	Adipose Tissue	Adrenal Gland	Amygdala	Bone	Bone Marrow	Brain	Dorsal Root Ganglia	Eye	Heart	Hindgut	Hypothalamus	Kidney	Liver	Lung	Lymph Nodes	Mammary Gland	Midgut	Neurons	Ovary	Pancreas	Pituitary Gland	Placenta	Prostate	Salivary Gland	Skeletal Muscle	Small Intestine	Spleen	Stomach	Testes	Uterus
Grin1	Psen1	15066262	biogrid	exp			G			G	G	G			G							G		G	G
Psen1	Sec61a1	20541250	biogrid	exp	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Efnb1	16511561	mint,intact	exp	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Stt3b	20541250	biogrid,intact	exp	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Pemt	22892566	intact	exp	G			G	G				G				G							G									G
Grin2a	Psen1	15066262	biogrid	exp
Psen1	Pld1	16449386	dip	exp	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G		G	G	G	G	G		G
Psen1	Tmed2	16641999	intact	exp
Psen1	Atp6v0a1	20541250	biogrid,intact	exp	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Calr	Psen1	23585889	intact	exp	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Psen2	15474363	biogrid	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Erlin2	22771797	biogrid,intact	exp, ortho
Pik3r1	Psen1	15192701	biogrid	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Dock3		i2d	exp, ortho
Cdh1	Psen1	11953314	biogrid	exp, ortho	G			G	G		G	G		G		G	G	G		G	G	G	G	G	G	G	G	G	G	G		G		G
Psen1	Aph1a	15474363,15146195	biogrid,mint,intact	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Aph1b	15146195	biogrid	exp, ortho
Psen1	Arc	22036569	intact	exp, ortho			G			G												G			G								G
Psen1	Psen1	15474363,22036569	biogrid,i2d,intact	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Ctnnb1	16126725,16306047,11104755	innatedb,biogrid,intact	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
App	Psen1	22036569	intact	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Notch4	Psen1	11518718	biogrid	exp, ortho	G	G						G	G			G		G		G	G		G	G	G	G			G			G	G
Psen1	Psenen	16641999,16449386,15474363,22036569	biogrid,intact,dip	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Gsap	20811458	dip	exp, ortho				G	G								G	G	G				G	G				G			G			G
Psen1	Unk	25737280	biogrid	exp, ortho	G	G	G	G	G	G		G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G		G	G	G	G
Psen1	Icam5		i2d	exp, ortho			G			G					G							G		G									G
Psen1	Notch1	11518718	biogrid	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Notch2	Psen1	11518718	biogrid	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Dll1	12794186	biogrid,i2d	exp, ortho	G		G		G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Gsk3b	12805290,11104755	biogrid	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Ncstn	16641999,11943765,15474363,22036569	biogrid,intact	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Notch3	11518718	biogrid	exp, ortho	G	G	G	G	G	G	G	G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Clstn1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Ctnnd2	Psen1			ortho			G			G	G	G			G							G		G	G
Psen1	Tcf7l2			ortho	G	G		G		G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Casp6	Psen1			ortho	G	G		G	G			G	G	G	G	G	G	G	G	G	G		G	G	G	G	G	G		G	G	G	G	G
Psen1	Kcnip3			ortho			G			G	G				G							G			G		G
Psen1	Cxcr1			ortho
Apba1	Psen1			ortho
Psmb1	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Casp7			ortho	G	G		G	G			G	G	G		G	G	G	G	G	G		G	G	G	G	G	G	G	G	G	G		G
Psen1	Rnf32			ortho		G	G	G	G	G	G	G	G	G	G			G			G	G	G	G	G			G		G	G	G	G
Psen1	Kank2			ortho	G	G				G	G	G	G	G		G	G	G	G	G		G	G	G		G	G	G	G		G	G		G
Psen1	Ndufa9			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Ubc	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Mapt	Psen1			ortho		G	G			G	G	G	G		G	G		G		G		G		G	G			G	G
Prkaca	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Dhx9	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Rad23a			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Npr1	Psen1			ortho		G
Bcl2	Psen1			ortho	G			G	G	G	G	G			G				G	G		G	G	G							G	G		G
Psen1	Gcdh			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Flna			ortho	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Prdx2			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Prkcz			ortho			G			G	G	G		G	G	G	G	G	G		G	G	G	G	G	G	G	G		G		G	G	G
Psen1	Cib1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Apoe	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Ncln			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Pram1			ortho
Psen1	Stambpl1			ortho	G	G	G	G	G	G	G	G	G	G	G			G	G	G	G	G	G	G	G	G	G	G		G	G	G	G	G
Srpk1	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Bcap31			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Cfl1	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Gfap	Psen1			ortho			G			G			G		G							G		G
Tp63	Psen1			ortho	G							G								G						G	G	G				G
Psen1	Sh2b2			ortho	G	G									G				G	G						G
Psen1	Itsn2			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Mtch1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Plxdc2			ortho	G	G	G	G	G	G	G	G	G	G	G	G		G	G	G		G	G	G	G	G	G	G	G		G	G		G
Psen1	Etfa			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Stx5			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Ets2	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Dner			ortho		G	G			G	G	G			G							G		G	G		G
Psen1	Ngfr			ortho							G	G							G			G	G					G			G		G	G
Stx1a	Psen1			ortho		G	G			G	G	G	G	G	G			G	G	G	G	G	G	G	G			G		G	G	G	G	G
Psen1	Ap1m2			ortho	G							G		G		G		G	G	G	G		G	G	G	G	G	G		G		G		G
Cdk5	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Rmdn3			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Scn5a			ortho			G			G	G	G			G							G			G
Psen1	Herpud1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Tuba1b	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Rpl10			ortho
Psen1	St13			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Irak2			ortho
Psen1	Epb41l3			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Pdcd4			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Tgfbr1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Cyp2c55			ortho										G			G				G								G	G		G
Ctnna1	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Gdi1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Fbxw7			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Bace1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Dag1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Actn1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Dsp	Psen1			ortho	G		G	G	G	G		G	G	G		G	G	G		G	G	G	G	G	G	G	G	G	G	G		G		G
Psen1	Tdp2			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Hspa5	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Kcnip4			ortho			G			G	G	G			G							G		G
Psen1	Rab11a			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Casp8	Psen1			ortho	G	G		G	G			G	G	G		G	G	G	G	G	G		G	G	G	G	G	G	G	G	G	G		G
Psen1	Fbxl12			ortho	G	G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Dsg2	Psen1			ortho	G	G						G	G	G		G	G	G	G	G	G		G	G	G	G	G	G	G	G		G		G
Psen1	Tcf4			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Pkp4			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Psma5			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Nos3			ortho	G	G	G			G	G	G	G		G	G	G	G	G	G		G	G	G	G			G	G		G	G	G	G
Psen1	Ndufs8			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Jup			ortho	G	G	G			G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Flnb			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Oxct1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Yme1l1	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Fgf13			ortho	G	G	G	G		G	G	G	G	G	G				G	G	G	G	G	G	G		G		G	G	G
Psen1	Riok3			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Scaf11			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Ctnnd1	Psen1			ortho	G	G	G	G		G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Bard1	Psen1			ortho
Psen1	Htra2			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Rab3a			ortho	G	G	G			G	G	G	G	G	G			G		G		G	G	G	G		G	G	G		G	G
Psen1	Rheb			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Tp53	Psen1			ortho	G	G	G	G	G	G	G			G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Vasn			ortho	G	G		G		G	G	G	G		G	G	G	G	G	G		G	G	G	G	G	G	G	G		G	G	G	G
Umps	Psen1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G	G	G	G	G	G	G
Psen1	Casp4			ortho	G			G	G					G				G	G	G	G					G				G	G	G		G
Psen1	Casp3			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Elk1	Psen1			ortho			G			G			G		G							G
Casp1	Psen1			ortho	G			G	G		G		G	G				G	G	G	G							G	G	G	G	G		G
Psen1	Dtna			ortho	G		G			G	G	G	G		G			G		G		G			G	G	G	G	G			G	G
Psen1	Efnb2			ortho	G	G	G			G	G	G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Ubqln1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Ern1			ortho				G	G																G	G		G
Psen1	Efhd1			ortho	G	G	G			G	G	G	G		G	G				G		G	G	G		G	G		G		G		G	G
Psen1	Grb2			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Cd44	Psen1			ortho	G	G		G	G		G	G	G	G	G		G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G		G
Psen1	Traf6			ortho	G	G		G				G		G	G	G		G	G	G	G		G	G		G	G	G		G	G	G		G
Psen1	Cdc37			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Cdh15	Psen1			ortho			G	G		G	G				G					G		G		G					G
Etv1	Psen1			ortho
Psen1	Ensa			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Ecsit			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G
Psen1	Bcl2l1			ortho	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G	G

PPI - iRefIndex
UniProt A	UniProt B	Method	PMID	Interaction Type	Edge type	Num Participants
Q8CIQ7	P49769	-	10854253	-	X	2
	P49769	-	15146195	-	C	3
Q61483	P49769	-	12794186	-	X	2
P49769	P49769	-	9666482	-	X	2
P49769	P49769	-	9666482	-	X	2
	P49769	-	11719200	-	X	2
P35436	P49769	affinity chromatography technology	15066262	physical association	X	2
Q01705	P49769	affinity chromatography technology	11518718	physical association	X	2
P49769		affinity chromatography technology	15146195	physical association	X	2
P49769		affinity chromatography technology	15474363	physical association	X	2
P49769		affinity chromatography technology	15474363	physical association	X	2
P49769		affinity chromatography technology	11953314	physical association	X	2
P49769		affinity chromatography technology	19376115	physical association	X	2
P49769	Q02248	affinity chromatography technology	11104755	physical association	X	2
Q61144	P49769	affinity chromatography technology	15474363	physical association	X	2
	P49769	affinity chromatography technology	11518718	physical association	X	2
Q61483	P49769	affinity chromatography technology	12794186	physical association	X	2
Q61483	P49769	enzymatic study	12794186	direct interaction	X	2
Q61982	P49769	affinity chromatography technology	11518718	physical association	X	2
P49769	Q8C7N7	affinity chromatography technology	15146195	physical association	X	2
P49769	P49769	affinity chromatography technology	15474363	physical association	X	2
P49769	Q9CQR7	affinity chromatography technology	15474363	physical association	X	2
P49769	Q3TP23	affinity chromatography technology	15192701	physical association	X	2
P49769	Q3TP23	affinity chromatography technology	15192701	physical association	X	2
P49769	A2AI14	affinity chromatography technology	15066262	physical association	X	2
	P49769	affinity chromatography technology	11518718	physical association	X	2
Q9WV60	P49769	affinity chromatography technology	12805290	physical association	X	2
Q9WV60	P49769	enzymatic study	11104755	direct interaction	X	2
Q8BFZ9	P49769	fluorescent resonance energy transfer	22771797	direct interaction	X	2
P57716	P49769	affinity chromatography technology	15474363	physical association	X	2
P57716	P49769	biochemical	11943765	colocalization	X	2
P57716	P49769	biochemical	11943765	colocalization	X	2
	P49769	coimmunoprecipitation	16641999	association	C	5
	P49769	electrophoretic mobility shift assay	14717705	association	C	4
	P49769	coimmunoprecipitation	17911105	association	C	4
	P49769	mass spectrometry studies of complexes	15146195	association	C	3
	P49769	pull down	15146195	association	C	3
	P49769	coimmunoprecipitation	15146195	association	C	3
	P49769	anti bait coimmunoprecipitation	10635315	association	C	4
	P49769	cosedimentation through density gradient	10635315	association	C	4
	P49769	anti bait coimmunoprecipitation	10635315	association	C	4
Q13393	P49769	anti tag coimmunoprecipitation	16449386	physical association	X	2
	P49769	anti bait coimmunoprecipitation	16449386	-	C	3
	P49769	molecular sieving	20811458	physical association	C	4
	P49769	anti bait coimmunoprecipitation	20811458	physical association	C	4
Q9Z280	P49769	anti bait coimmunoprecipitation	16449386	physical association	X	2
Q9Z280	P49769	anti bait coimmunoprecipitation	16449386	physical association	X	2
P49769	Q9CQR7	anti bait coimmunoprecipitation	16449386	physical association	X	2
P49769	Q3TCV3	anti bait coimmunoprecipitation	20811458	physical association	X	2
	P49769	anti bait coimmunoprecipitation	22036569	association	C	3
	P49769	anti tag coimmunoprecipitation	19376115	association	C	4
	P49769	anti bait coimmunoprecipitation	16641999	association	C	3
	P49769	cosedimentation through density gradient	22892566	colocalization	C	3
	P49769	pull down	16306047	association	C	3
	P49769	cosedimentation through density gradient	22036569	physical association	C	11
	P49769	cosedimentation through density gradient	22036569	physical association	C	11
Q9Z1G4	P49769	anti bait coimmunoprecipitation	20541250	physical association	X	2
Q9Z1G4	P49769	anti bait coimmunoprecipitation	20541250	physical association	X	2
Q8BVF7	P49769	cross-linking study	15146195	physical association	X	2
Q3TDQ1	P49769	anti bait coimmunoprecipitation	20541250	physical association	X	2
P52795	P49769	anti bait coimmunoprecipitation	16511561	physical association	X	2
P52795	P49769	anti bait coimmunoprecipitation	16511561	physical association	X	2
Q9R0Q3	P49769	anti bait coimmunoprecipitation	16641999	physical association	X	2
P49769	Q02248	pull down	16306047	physical association	X	2
P49769	Q9WV31	anti bait coimmunoprecipitation	22036569	physical association	X	2
	P49769	pull down	16306047	association	C	3
	P49769	anti bait coimmunoprecipitation	22036569	physical association	C	3
	P49769	anti bait coimmunoprecipitation	22036569	physical association	C	3
	P49769	anti bait coimmunoprecipitation	22036569	association	C	4
	P49769	anti bait coimmunoprecipitation	22036569	association	C	4
	P49769	anti tag coimmunoprecipitation	19376115	association	C	4
P49769	P14923	pull down	16306047	physical association	X	2
Q8BFZ9	P49769	proximity ligation assay	22771797	physical association	X	2
Q8BFZ9	P49769	proximity ligation assay	22771797	physical association	X	2
P14211	P49769	anti bait coimmunoprecipitation	23585889	physical association	X	2
P14211	P49769	anti bait coimmunoprecipitation	23585889	physical association	X	2
P14211	P49769	confocal microscopy	23585889	colocalization	X	2
P49769	P49769	cross-linking study	9666482	-	X	2
P49769	P49769	coimmunoprecipitation	9666482	-	X	2

PPI - PINA
Gene A	Gene B	Method	Publications	Species A	Species B	Interaction Type	Source Database	Interaction Identidiers	Experimental Role(s) Interactor A	Experimental Role(s) Interactor B
Calr	Psen1	MI:0006(anti bait coimmunoprecipitation)\|MI:0006(anti bait coimmunoprecipitation)\|MI:0006(anti bait coimmunoprecipitation)	23585889	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0403(colocalization)\|MI:0915(physical association)	(intact)\|(intact)\|(intact)	UniProt_177049\|UniProt_177062\|UniProt_177050	prey\|neutral component\|bait	bait\|neutral component\|prey
Cdh1	Psen1	MI:0004(affinity chromatography technology)	11953314	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_324253	prey	bait
Psen1	Efnb1	MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)\|MI:0007(anti tag coimmunoprecipitation)	16511561	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)	(intact)\|(intact)\|MI:0471(mint)\|MI:0471(mint)	UniProt_167529\|UniProt_167530\|MINT_80994\|MINT_80997	prey\|bait\|bait\|prey	bait\|prey\|prey\|bait
Psen1	Aph1b	MI:0004(affinity chromatography technology)	15146195	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_323250	prey	bait
Psen1	Aph1a	MI:0004(affinity chromatography technology)\|MI:0030(cross-linking study)\|MI:0030(cross-linking study)\|MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	15146195,15474363	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)	(biogrid)\|MI:0471(mint)\|(intact)\|(biogrid)\|(biogrid)	BIOGRID_323973\|MINT_57932\|UniProt_165273\|BIOGRID_323979\|BIOGRID_323252	bait\|prey\|prey\|prey\|prey	prey\|bait\|bait\|bait\|bait
Psen1	Arc	MI:0071(molecular sieving)\|MI:0071(molecular sieving)\|MI:0071(molecular sieving)\|MI:0071(molecular sieving)\|MI:0071(molecular sieving)	22036569	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)\|MI:0914(association)\|MI:0915(physical association)\|MI:0915(physical association)	(intact)\|(intact)\|(intact)\|(intact)\|(intact)	UniProt_184533\|UniProt_174183\|UniProt_174187\|UniProt_174186\|UniProt_174185	null\|null\|null\|null\|null	neutral component\|neutral component\|bait\|prey\|bait
Psen1	Notch1	MI:0004(affinity chromatography technology)	11518718	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_325019	bait	prey
Psen1	Gsk3b	MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	11104755,12805290	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0407(direct interaction)	(biogrid)\|(biogrid)	BIOGRID_325716\|BIOGRID_319696	bait\|prey	prey\|bait
Notch2	Psen1	MI:0004(affinity chromatography technology)	11518718	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_325020	prey	bait
Psen1	Psenen	MI:0071(molecular sieving)\|MI:0006(anti bait coimmunoprecipitation)\|MI:0004(affinity chromatography technology)	15474363,16641999,22036569	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0914(association)\|MI:0914(association)\|MI:0915(physical association)	(intact)\|(intact)\|(biogrid)	UniProt_174188\|UniProt_166127\|BIOGRID_323972	null\|bait\|bait	prey\|prey\|prey
Psen1	Erlin2	MI:0096(pull down)\|MI:0096(pull down)	22771797	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)	(intact)\|(intact)	UniProt_174590\|UniProt_174591	neutral component\|neutral component	neutral component\|neutral component
Psen1	Notch3	MI:0004(affinity chromatography technology)	11518718	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_325021	bait	prey
Grin1	Psen1	MI:0004(affinity chromatography technology)	15066262	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_328526	prey	bait
Psen1	Atp6v0a1	MI:0416(fluorescence microscopy)\|MI:0416(fluorescence microscopy)	20541250	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)	(intact)\|(intact)	UniProt_170897\|UniProt_170898	prey\|bait	bait\|prey
Psen1	Tmed2	MI:0006(anti bait coimmunoprecipitation)	16641999	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(intact)	UniProt_166124	bait	prey
Psen1	Stt3b	MI:0416(fluorescence microscopy)	20541250	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(intact)	UniProt_170899	prey	bait
Psen1	Psen2	MI:0004(affinity chromatography technology)	15474363	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_323975	prey	bait
Notch4	Psen1	MI:0004(affinity chromatography technology)	11518718	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_325022	prey	bait
Psen1	Dll1	MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	12794186	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0407(direct interaction)	(biogrid)\|(biogrid)	BIOGRID_327825\|BIOGRID_327826	bait\|bait	prey\|prey
Pik3r1	Psen1	MI:0004(affinity chromatography technology)\|MI:0004(affinity chromatography technology)	15192701	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)	(biogrid)\|(biogrid)	BIOGRID_327911\|BIOGRID_327910	bait\|prey	prey\|bait
Psen1	Ctnnb1	MI:0004(affinity chromatography technology)\|MI:0006(anti bait coimmunoprecipitation)\|MI:0006(anti bait coimmunoprecipitation)	11104755,16306047	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)\|MI:0915(physical association)\|MI:0915(physical association)	(biogrid)\|(intact)\|(intact)	BIOGRID_315515\|UniProt_166557\|UniProt_82292	bait\|prey\|prey	prey\|bait\|bait
Psen1	Ncstn	MI:0071(molecular sieving)\|MI:0006(anti bait coimmunoprecipitation)\|MI:0004(affinity chromatography technology)\|MI:0401(biochemical)\|MI:0401(biochemical)\|MI:0071(molecular sieving)\|MI:0071(molecular sieving)	11943765,15474363,16641999,22036569	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0914(association)\|MI:0914(association)\|MI:0915(physical association)\|MI:0403(colocalization)\|MI:0403(colocalization)\|MI:0915(physical association)\|MI:0915(physical association)	(intact)\|(intact)\|(biogrid)\|(biogrid)\|(biogrid)\|(intact)\|(intact)	UniProt_174188\|UniProt_166127\|BIOGRID_323970\|BIOGRID_329530\|BIOGRID_329529\|UniProt_184533\|UniProt_174183	null\|bait\|bait\|prey\|bait\|null\|null	prey\|prey\|prey\|bait\|prey\|neutral component\|neutral component
Grin2a	Psen1	MI:0004(affinity chromatography technology)	15066262	taxid:10090(Mus musculus)	taxid:10090(Mus musculus)	MI:0915(physical association)	(biogrid)	BIOGRID_328527	prey	bait

PPI - HINT
Gene A	Gene B	PMID	Method	Quality
APP	PSEN1	22036569	0029	LC
SYT1	PSEN1	27036734,27036734,27036734	0055,0663,0006	LC
PSEN1	PSEN1	9666482,9666482	0019,0030	LC
PSEN1	NCSTN	11943765	0401	LC
PSEN1	PEMT	22892566	0029	LC
PSEN1	ERLIN2	22771797,22771797	0055,0813	LC
PSEN1	APH1A	15146195,15146195	0030,0004	LC
PSEN1	GSK3B	11104755	0415	LC
NOTCH2	PSEN1	11518718	0004	LC
SYN1	PSEN1	27036734	0663	LC
CDH1	PSEN1	11953314	0004	LC
CALR	PSEN1	23585889,23585889	0663,0006	LC
PIK3R1	PSEN1	15192701	0004	LC
NOTCH4	PSEN1	11518718	0004	LC
GRIN2A	PSEN1	15066262	0004	LC
GRIN1	PSEN1	15066262	0004	LC
SYT1	PSEN1	27036734,27036734,27036734	0055,0663,0006	LC
PSEN1	PSEN1	22036569,15474363	0006,0004	LC
PSEN1	EFNB1	16511561	0006	LC
PSEN1	NCSTN	11943765,22036569,15474363,16641999	0401,0006,0004,0006	LC
PSEN1	SEC61A1	20541250	0004	LC
PSEN1	NOTCH1	11518718	0004	LC
PSEN1	CTNNB1	16306047,11104755	0096,0004	LC
PSEN1	GSAP	20811458	0006	LC
PSEN1	STT3B	20541250,20541250	0004,0006	LC
PSEN1	PSEN2	15474363	0004	LC
PSEN1	DLL1	12794186	0004	LC
PSEN1	NOTCH3	11518718	0004	LC
PSEN1	ERLIN2	22771797,22771797	0055,0813	LC
PSEN1	APH1A	15146195,15474363,15146195	0030,0004,0004	LC
PSEN1	APH1B	15146195	0004	LC
PSEN1	PSENEN	22036569,15474363,16449386,16641999	0006,0004,0006,0006	LC
PSEN1	TMED2	16641999	0006	LC
PSEN1	ARC	22036569	0006	LC
PSEN1	GSK3B	12805290	0004	LC
PSEN1	ATP6V0A1	20541250,20541250	0004,0006	LC
PSEN1	PLD1	16449386	0006	LC

PPI - Mentha
Protein A	Protein B	Gene A	Gene B	Score	PMID
P57716	P49769	NCSTN	PSEN1	0.623	22036569,15474363,11943765,16641999
P61620	P49769	SEC61A1	PSEN1	0.21	20541250
Q61144	P49769	PSEN2	PSEN1	0.21	15474363
Q61907	P49769	PEMT	PSEN1	0.126	22892566
Q9NQB0	P49769	TCF7L2	PSEN1	0.21	16306047
Q9Z1G4	P49769	ATP6V0A1	PSEN1	0.507	20541250
Q8BL48	P49769	UNK	PSEN1	0.126	25737280
Q8C7N7	P49769	APH1B	PSEN1	0.126	15146195
P49769	P12023	PSEN1	APP	0.21	22036569
Q96BI3	P49769	APH1A	PSEN1	0.376	19376115
P49769	P46096	PSEN1	SYT1	0.463	27036734
Q02248	P49769	CTNNB1	PSEN1	0.376	11104755,16306047
P49769	P49769	PSEN1	PSEN1	0.554	22036569,15474363
Q9CQR7	P49769	PSENEN	PSEN1	0.507	22036569,16641999,15474363
P49769	P26450	PSEN1	PIK3R1	0.376	15192701
P49769	P49768	PSEN1	PSEN1	0.126	27036734
P49769	O35516	PSEN1	NOTCH2	0.21	11518718
P49769	O88935	PSEN1	SYN1	0.081	27036734
P49769	P09803	PSEN1	CDH1	0.21	11953314
P49769	P14211	PSEN1	CALR	0.309	23585889
P49769	P31695	PSEN1	NOTCH4	0.21	11518718
P49769	P35436	PSEN1	GRIN2A	0.21	15066262
P49769	P35438	PSEN1	GRIN1	0.21	15066262
Q01705	P49769	NOTCH1	PSEN1	0.21	11518718
Q3TDQ1	P49769	STT3B	PSEN1	0.376	20541250
Q61483	P49769	DLL1	PSEN1	0.21	12794186
Q61982	P49769	NOTCH3	PSEN1	0.21	11518718
Q8BFZ9	P49769	ERLIN2	PSEN1	0.454	22771797
Q8BVF7	P49769	APH1A	PSEN1	0.523	15146195,15474363
Q9R0Q3	P49769	TMED2	PSEN1	0.21	16641999
Q9WV31	P49769	ARC	PSEN1	0.376	22036569
Q9WV60	P49769	GSK3B	PSEN1	0.454	11104755,12805290
P49769	P14923	PSEN1	JUP	0.21	16306047
P52795	P49769	EFNB1	PSEN1	0.21	16511561