PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhab Tbk1 16635246 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptpn11 Tbk1 17954568 innatedb exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dok3 Tbk1 24929003 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx41 Tbk1 21892174 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G Rnf41 Tbk1 19483718 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rab8b Tbk1 22921120 innatedb exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Irf1 Tbk1 17468758 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eed Tbk1 24457600 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Zbp1 Tbk1 18375758,17618271 innatedb,dip exp G G G G G G G G G G G G G G Tmem173 Tbk1 23028052,22728658,23142775,22000020 innatedb,intact,dip exp, ortho G G G G G G G G G G G G G G G G G G G G G Tlr3 Tbk1 21911421 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G Irf3 Tbk1 21862579 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf2 Tbk1 10581243 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G Tbk1 Tbk1 23746807 biogrid,dip exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx58 Tbk1 18977754,23950712 innatedb,biogrid exp, ortho P Mib1 Tbk1 21903422 biogrid,intact exp, ortho P G G G G G G G G G Chuk Tbk1 21949249 innatedb exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat6 Tbk1 22000020 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ticam1 Tbk1 21441935,17327220,20100929,22454496 innatedb,intact,dip exp, ortho Ubc Tbk1 21903422,19483718 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Azi2 Tbk1 21903422,17568778,18583960 innatedb,biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Optn Tbk1 20174559,21862579 innatedb,biogrid exp, ortho Tank Tbk1 10581243,17568778,17327220,18583960,23746807,21949249 innatedb,mint,intact,dip exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx3x Tbk1 18583960 innatedb,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tlr4 Tbk1 21911421 innatedb exp, ortho G G G G G G G G G G G G G G G G G Traip Tbk1 22945920 biogrid exp, ortho G G G G G G G G Traf3 Tbk1 17823124,17327220,20100929 innatedb exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Traf3ip2, TRAF3 interacting protein 2, Traf3 interacting protein 2, cDNA fis, clone TRACH2006870,moderately similar to Homo sapiens adaptor protein CIKS mRNA Tbk1 22851696 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G Syk Tbk1 23962979 biogrid exp, ortho GP G G G G G G G G G G G G G G G G Tbkbp1 Tbk1 17568778,18583960 innatedb,mint,intact exp, ortho Ikbkg Tbk1 21949249 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikbkb Tbk1 21949249 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Akt1 Tbk1 21106850 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map3k14 Tbk1 23023393 intact exp, ortho G G G G G G G G G Stx11 Tbk1 ortho Stx19 Tbk1 ortho G G Mbp Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G Mib2 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ruvbl2 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep44 Tbk1 ortho Tubb5 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp5 Tbk1 ortho Mavs Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Nck1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp5a1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl11 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sike1 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rel Tbk1 ortho G G G G Fmr1 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbk1 Fxr2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep152 Tbk1 ortho G G G G G Cntrob Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stil Tbk1 ortho G G G Cdc42bpg Tbk1 ortho P Socs3 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Casp8 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Src Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Txlng Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ssx2ip Tbk1 ortho G G G G G G G G G G G G G G G G G G G G Cct8 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim10 Tbk1 ortho G G G G G Cep128 Tbk1 ortho Sass6 Tbk1 ortho G G G G G G G G G G G G G Irf5 Tbk1 ortho G G G G G G G G G G G G G G G G G G G Nono Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tax1bp1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rara Tbk1 ortho G G Nfkb2 Tbk1 ortho P G G G G G G G G G G G G G Hspa9 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf11 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Txlna Tbk1 ortho P Mtpap Tbk1 ortho Prkar2a Tbk1 ortho GP G G G G G G G G G G G G G G G G G G Riok3 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct2 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nfkb1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp5c Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct7 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncoa2 Tbk1 ortho G G G G G Hnrnpm Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tlr9 Tbk1 ortho G G Cct3 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sclt1 Tbk1 ortho G G G G Dtx4 Tbk1 ortho Tcp1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G 9030611K07Rik Tbk1 ortho Tomm70a Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rela Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Tbk1 ortho Ago2 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G App Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp2 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Egfr Tbk1 ortho GP G G G G G G G G G G G G G G G G G Btrc Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct5 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xiap Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Irf7 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Sqstm1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Skp1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg9a Tbk1 ortho Ankrd28 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim14 Tbk1 ortho Map1lc3b Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa8 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Herc2 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa5 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnf Tbk1 ortho Cep63 Tbk1 ortho Rb1cc1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Apba3 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim27 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccdc8 Tbk1 ortho Cct4 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med4 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp6c Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc37 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lats2 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stx12 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ofd1 Tbk1 ortho G G G G G G G G G G G G G G G G Exoc2 Tbk1 ortho P Pkm Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ldhb Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ruvbl1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Odf2 Tbk1 ortho G G G G Ppp6r2 Tbk1 ortho P G G G G G G G G Ikbke Tbk1 ortho G G G G G G G G G G G G G Hsp90ab1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf6 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G Ywhae Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Peli1 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbk1 Elf4 ortho G G G G G G Tubb4a Tbk1 ortho P G G G G G G G G G G G G G G G G G G G Cyld Tbk1 ortho Lgals3bp Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sfpq Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl7 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep135 Tbk1 ortho P Tbk1 Nfkbia ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntn1 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Rps5 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps8 Tbk1 ortho P Hmmr Tbk1 ortho G G G G G G G G G G G G G G Ppp6r1 Tbk1 ortho P Bbox1 Tbk1 ortho G G G G G G G Xpo1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfaip3 Tbk1 ortho G G G G G Arhgef2 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G Stx3 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Ninl Tbk1 ortho Exoc4 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps18 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbk1 Letm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pros1 Tbk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbk1 Tnip1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsp90aa1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P48025 Q9WUN2 affinity chromatography technology 23962979 physical association X 2 P0CG50 Q9WUN2 affinity chromatography technology 19483718 physical association X 2 P0CG50 Q9WUN2 affinity chromatography technology 21903422 physical association X 2 Q3U5M1 Q9WUN2 enzymatic study 17468758 direct interaction X 2 Q8BH75 Q9WUN2 affinity chromatography technology 19483718 physical association X 2 Q8BH75 Q9WUN2 enzymatic study 19483718 direct interaction X 2 Q80SY4 Q9WUN2 affinity chromatography technology 21903422 physical association X 2 Q9WUN2 affinity chromatography technology 10581243 physical association X 2 Q9WUN2 pull down 10581243 direct interaction X 2 Q8N7N6 Q9WUN2 enzymatic study 22851696 direct interaction X 2 P70671 Q9WUN2 affinity chromatography technology 21862579 physical association X 2 P70671 Q9WUN2 enzymatic study 21862579 direct interaction X 2 Q8VIG6 Q9WUN2 affinity chromatography technology 22945920 physical association X 2 Q921E6 Q9WUN2 affinity chromatography technology 24457600 physical association X 2 Q9WUN2 Q9WUN2 x-ray crystallography 23746807 association X 2 Q8K3K8 Q9WUN2 affinity chromatography technology 21862579 physical association X 2 Q8K3K8 Q9WUN2 enzymatic study 21862579 direct interaction X 2 Q6Q899 Q9WUN2 affinity chromatography technology 23950712 physical association X 2 Q9QYP6-3 Q9WUN2 affinity chromatography technology 21903422 physical association X 2 P10914 Q9WUN2 enzymatic study 23746807 direct interaction X 2 Q14653 Q9WUN2 protein kinase assay 23746807 direct interaction X 2 Q3TBT3 Q9WUN2 protein kinase assay 22728658 direct interaction X 2 Q9WUN2 Q9WUN2 protein kinase assay 23746807 direct interaction Y 1 Q9WUN2 Q9WUN2 molecular sieving 23746807 direct interaction Y 1 Q9WUN2 Q9WUN2 protein kinase assay 22728658 direct interaction Y 1 Q9WUN2 Q9WUN2 x-ray crystallography 23746807 direct interaction Y 1 Q9WUN2 Q9WUN2 protein kinase assay 23746807 direct interaction Y 1 P70347 Q9WUN2 pull down 23746807 direct interaction X 2 Q80UF7 Q9WUN2 anti bait coimmunoprecipitation 22454496 physical association X 2 A2APF7 Q9WUN2 anti tag coimmunoprecipitation 18375758 physical association X 2 Q9WUN2 cosedimentation through density gradient 16635246 colocalization C 608 Q9WUN2 anti tag coimmunoprecipitation 10581243 direct interaction C 3 Q9WUN2 anti tag coimmunoprecipitation 10581243 direct interaction C 3 Q9WUN2 anti bait coimmunoprecipitation 21892174 association C 3 Q9WUN2 anti bait coimmunoprecipitation 23023393 association C 3 Q9WUN2 anti bait coimmunoprecipitation 22000020 association C 3 Q9WUN2 anti bait coimmunoprecipitation 22000020 association C 3 Q9WUN2 anti bait coimmunoprecipitation 21903422 association C 3 Q3TBT3 Q9WUN2 anti bait coimmunoprecipitation 23142775 physical association X 2 P70347 Q9WUN2 anti tag coimmunoprecipitation 10581243 direct interaction X 2 P70347 Q9WUN2 anti tag coimmunoprecipitation 10581243 direct interaction X 2 P70347 Q9WUN2 anti tag coimmunoprecipitation 18583960 physical association X 2 Q80UF7 Q9WUN2 anti bait coimmunoprecipitation 21441935 physical association X 2 Q9WUN2 tandem affinity purification 18583960 association C 4 A2A9T0 Q9WUN2 anti tag coimmunoprecipitation 18583960 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Irf3 Tbk1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21862579 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_321758|BIOGRID_321757 prey|prey bait|bait Optn Tbk1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 21862579 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_321759|BIOGRID_321756 prey|prey bait|bait Syk Tbk1 MI:0004(affinity chromatography technology) 23962979 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_331443 bait prey Zbp1 Tbk1 MI:0007(anti tag coimmunoprecipitation) 18375758 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) MI:0465(dip) DIP_433 - - Irf1 Tbk1 MI:0004(affinity chromatography technology) 17468758 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_321553 prey bait Tbk1 Tbkbp1 MI:0424(protein kinase assay)|MI:0424(protein kinase assay)|MI:0424(protein kinase assay)|MI:0424(protein kinase assay) 18583960 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association) MI:0471(mint)|(intact)|MI:0471(mint)|(intact) MINT_70013|UniProt_169797|MINT_70017|UniProt_169798 bait|bait|bait|bait prey|prey|prey|prey Traip Tbk1 MI:0004(affinity chromatography technology) 22945920 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322285 prey bait Tmem173 Tbk1 MI:0006(anti bait coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 22000020,23142775 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(intact) UniProt_173915|UniProt_174509|UniProt_174508 bait|bait|bait prey|prey|prey Eed Tbk1 MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332344 bait prey Traf3ip2 Tbk1 MI:0004(affinity chromatography technology) 22851696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_327538 prey bait Ubc Tbk1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19483718,21903422 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_321649|BIOGRID_331645 prey|prey bait|bait Azi2 Tbk1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_331646|UniProt_172673 prey|prey bait|bait Mib1 Tbk1 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation) 21903422 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_331647|UniProt_172673 prey|prey bait|bait Ddx58 Tbk1 MI:0004(affinity chromatography technology) 23950712 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_331436 bait prey Ticam1 Tbk1 MI:0006(anti bait coimmunoprecipitation) 21441935 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_171906 bait prey Tank Tbk1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0424(protein kinase assay)|MI:0424(protein kinase assay)|MI:0424(protein kinase assay)|MI:0424(protein kinase assay)|MI:0018(two hybrid)|MI:0018(two hybrid) 10581243,18583960 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|MI:0471(mint)|(intact)|MI:0471(mint)|(intact)|(intact)|(intact) UniProt_160906|UniProt_160905|MINT_70013|UniProt_169797|MINT_70016|UniProt_169799|UniProt_160903|UniProt_160904 prey|prey|prey|prey|prey|prey|prey|prey bait|bait|bait|bait|bait|bait|bait|bait Rnf41 Tbk1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19483718 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_321645|BIOGRID_321651 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality IRF1 TBK1 17468758 0415 LC TANK TBK1 17568778 0729 LC IRF3 TBK1 21862579,21862579 0004,0415 LC TMEM173 TBK1 22728658 0424 LC RNF41 TBK1 19483718,19483718,19483718 0004,0415,0007 LC OPTN TBK1 21862579,21862579 0004,0415 LC TRAF3IP2 TBK1 22851696 0415 LC YWHAB TBK1 16635246 0029 LC AZI2 TBK1 17568778 0729 LC TBK1 TBK1 23746807,23746807,22728658,23746807 0114,0424,0424,0071 LC TBKBP1 TBK1 18583960,18583960 0676,0007 LC UBC TBK1 19483718,21903422 0004,0004 LC AKT1 TBK1 21106850 0007 LC TRAF2 TBK1 10581243 0007 LC SYK TBK1 23962979 0004 LC RAB8B TBK1 22921120 0813 LC TANK TBK1 10581243,17327220,18583960,18583960,23746807 0007,0007,0676,0007,0096 LC IRF3 TBK1 21862579,21862579 0004,0415 LC TMEM173 TBK1 22000020,23142775 0006,0006 LC TRAF3 TBK1 17327220,26474655,20100929,17823124 0007,0004,0007,0007 LC DDX3X TBK1 18583960 0676 LC DDX58 TBK1 18977754,23950712 0007,0004 LC MIB1 TBK1 21903422,21903422 0006,0004 LC TICAM1 TBK1 21441935,22454496 0006,0006 LC RNF41 TBK1 19483718,19483718,19483718 0004,0415,0007 LC OPTN TBK1 21862579,21862579,20174559 0004,0415,0007 LC TRAIP TBK1 22945920 0004 LC DDX41 TBK1 21892174 0006 LC EED TBK1 24457600 0004 LC ZBP1 TBK1 18375758,17618271 0007,0007 LC AZI2 TBK1 18583960,21903422,21903422 0676,0006,0004 LC MAP3K14 TBK1 23023393 0006 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9WUN2 Q60803 TBK1 TRAF3 0.21 26474655 Q9WUN2 Q8K3K8 TBK1 OPTN 0.569 27086836,21862579 Q9WUN2 P15314 TBK1 IRF1 0.309 17468758 Q9WUN2 P10914 TBK1 IRF1 0.309 23746807 Q9WUN2 Q8VIG6 TBK1 TRAIP 0.21 22945920 Q9WUN2 P39429 TBK1 TRAF2 0.309 10581243 Q9WUN2 Q62167 TBK1 DDX3X 0.376 18583960 Q9WUN2 Q9WUN2 TBK1 TBK1 0.332 23746807 Q9WUN2 Q96CV9 TBK1 OPTN 0.21 26376340 Q9WUN2 Q9QY24 TBK1 ZBP1 0.21 18375758 Q9WUN2 Q6Q899 TBK1 DDX58 0.21 23950712 Q9WUN2 P0CG50 TBK1 UBC 0.309 21903422,19483718 Q9WUN2 P70671 TBK1 IRF3 0.454 21862579 Q9WUN2 Q80SY4 TBK1 MIB1 0.236 21903422 Q9WUN2 Q92844 TBK1 TANK 0.454 10581243 Q9WUN2 Q9QYP6 TBK1 AZI2 0.236 21903422 Q9WUN2 Q8BH75 TBK1 RNF41 0.454 19483718 Q9WUN2 Q921E6 TBK1 EED 0.126 24457600 Q9WUN2 Q9CQV8 TBK1 YWHAB 0.081 16635246 Q9WUN2 P70347 TBK1 TANK 0.765 18583960,10581243 Q9WUN2 P48025 TBK1 SYK 0.21 23962979 Q9WUN2 Q3TBT3 TBK1 TMEM173 0.21 22000020 Q9WUN2 A2A9T0 TBK1 TBKBP1 0.61 18583960