PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Gnb2l1 Desi1 22370726 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhaz Gnb2l1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Zfp819 22674187 intact exp Gnb2l1 Shc1 i2d exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Grin1 Gnb2l1 16635246 intact exp G G G G G G G G Gnb2l1 Ywhah 21311561 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Acta1 17205597 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G Nedd9 Gnb2l1 20697350 biogrid,intact exp G G G G G G G G G G G G G G G G G G G G G G G Irs1 Gnb2l1 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Hsd3b4 16615898 intact exp Bmpr2 Gnb2l1 17515463 innatedb exp G G G G G G G G G G G G G G G G G G G G Gnb2l1 Irs2 i2d exp G G G G G G G G G G G G G G G G G G G G Gnb2l1 Hsd3b7 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aldoa Gnb2l1 15627969 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptpn11 Gnb2l1 i2d exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rpgrip1l 21565611 intact exp Htt Gnb2l1 17500595 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Gnb2l1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Grin2b 16635246 intact exp, ortho G G G G G Stat3 Gnb2l1 16382134 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Itgb1 Gnb2l1 i2d exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Gnb2l1 19834914 intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Eed 24457600 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikbkb Gnb2l1 24323043,15102471 innatedb,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Gnb2l1 23649778 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Park7 24947010 intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tp73 18194455 intact exp, ortho G Gnb2l1 Unk 25737280 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tyk2 15240704 innatedb exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Chuk 24323043 innatedb exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb1 Gnb2l1 12359736 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pias2 22210188 mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Igf1r i2d exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp5 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Abcc3 Gnb2l1 ortho G G G G G G G G G G G G G G G G G Dgcr14 Gnb2l1 ortho G G G G G G G G G G G G G G G G G Gnb2l1 Rhoa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp6v1b2 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aurkb Gnb2l1 ortho G G G G G G G G G G G G G Gnb2l1 Stau1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Fem1b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rps21 ortho P Gnb2l1 Rnf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkcd Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rps9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Plcg1 ortho P Protein Slc27a6 Gnb2l1 ortho Ncam1 Gnb2l1 ortho G G G G G G G G G G G G G G G G G Ar Gnb2l1 ortho G G G G G G G G G G G G G G G G Anxa2 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vcam1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Lsm12 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa9 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl12 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eef1a1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psma2 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pacs2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nr3c1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tnrc6c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Nat10 ortho P Rb1 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptn Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G Kif4 Gnb2l1 ortho G G G G G G G G G G Gnb2l1 Cul2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Krr1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wdr76 Gnb2l1 ortho Gnb2l1 Hif1a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps20 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcbp1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kcnab1 Gnb2l1 ortho GP G G G G G G G G G G G G G Rpl26 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ube2t ortho P G G G G G G G G G G G G Gnb2l1 Riok3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 Gnb2l1 ortho P G G G G G G G G G G G G G G Rps13 Gnb2l1 ortho P G G G G G G G G G G G G Gnb2l1 Ccdc58 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ik ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbl Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tollip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rpa1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Il2rb Gnb2l1 ortho G G G G G G Gnb2l1 Ntrk1 ortho Bmi1 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Plec ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Naa11 ortho P G Gnb2l1 Vcl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Hspa4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsp90b1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Csnk1d ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tardbp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Srek1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Dync1li2 ortho P Rab7a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tp53bp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3e Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jak1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Smpd3 ortho GP G G G G G G G G G G Gnb2l1 Syncrip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Sap25 ortho Gnb2l1 Rpl15 ortho P Gnb2l1 Lrrk2 ortho GP G G G G G G G G G G G G G G G G G G G G Gnb2l1 Fbxo6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Birc6 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Cul7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ak6 ortho P Cftr Gnb2l1 ortho G G G G G G G G Ptprm Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tuba1c ortho P Gnb2l1 Cand1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Epor Gnb2l1 ortho G G G G G G G G G G G G G G G G G Ifnar1 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkar2a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G Gnb2l1 Sumo3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sfn Gnb2l1 ortho P G G G G G G G G Gnb2l1 Mtor ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rps27l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bysl Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Mapk9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Prpf31 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Rasa1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Src Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Eif6 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Eif3b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps16 Gnb2l1 ortho P Gnb2l1 Ago2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tubb5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Yars ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Cdc42bpa ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Mdc1 ortho P Gnb2l1 Golm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl5 Gnb2l1 ortho P Gnb2l1 Cab39 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkg1 Gnb2l1 ortho G G G G G G G Gnb2l1 Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 ortho P G G G G Gnb2l1 Ppid ortho P Ddx6 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Lias ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Dctn2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Agtrap ortho GP G G G G G G G G G G G G G G G G Gnb2l1 Cul3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Npm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pan2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sat1 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Coro1c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl7a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Cdk2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Eif3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkca Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G Stat1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps6 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Prkab2 ortho Gnb2l1 Mapk7 ortho G G G G G G G G G G G Gnb2l1 Dnaja4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tial1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd4 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Got1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ccbl2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Tln1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Prkd1 ortho GP G G G G G G G G G G G G G G G G G Gnb2l1 Trim45 ortho Hsd17b4 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnajc2 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rpl4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbxa2r Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G Polr1a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl27a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Stip1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Mki67 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G Psmc3 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Lrp12 ortho Gnb2l1 Protein Ddx19b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 H2afv ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dhx15 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Il4r Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G Gnb2l1 Kat2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Denr ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps2 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rpl19 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pwp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tpp2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Esr2 Gnb2l1 ortho G Nsmaf Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Hnrnph2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabrb3 Gnb2l1 ortho G G G G G G G Gng2 Gnb2l1 ortho G G G G G G G G G G G G G G Gnb2l1 Rnf185 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rad17 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ptov1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Syn2 ortho GP G G G G G G G G G G G G G Gnb2l1 Slc6a3 ortho G Gnb2l1 Mapk6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Tceb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ppp2r1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkce Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Nop56 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mid1 Gnb2l1 ortho Gnb2l1 Lsm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ect2 ortho G G G G G G G G G G G G G Thoc2 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pts ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pxn ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Gnb2l1 ortho G G G G G G G G G G G G G Gnb2l1 Stat2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Prkcb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Camk1d ortho P G G G G G G G G G G G G G G G G G G G G G G G G G G Itgb5 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Elavl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Slc9a3r1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Egfr ortho GP G G G G G G G G G G G G G G G G G Syt1 Gnb2l1 ortho P G G G G G G G G G Esr1 Gnb2l1 ortho G G G G G Gnb2l1 Mapk8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Isg15 ortho P Gnb2l1 Acss1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Adrb2 Gnb2l1 ortho G G G G G G G G G Gnb2l1 Psmd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps25 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Cherp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl7 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct8 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Wipi1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lyn Gnb2l1 ortho P Nfkb1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops5 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Wdr83 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Slc2a4 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G Gnb2l1 Alk ortho G G G G G Rpl23a Gnb2l1 ortho P Psmd14 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl21 Gnb2l1 ortho P Grap2 Gnb2l1 ortho Smurf2 Gnb2l1 ortho Gnb2l1 Cbx8 ortho G G G G G G G G G G G Dnm1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Cul1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Glyr1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ruvbl2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Mapkap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Fbxw2 ortho G G G G G G G G G G G G G G G G G G G G G G Rps8 Gnb2l1 ortho P Gnb2l1 Psmb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf1a Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ccna1 ortho G Rps3 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Utp23 ortho Tp63 Gnb2l1 ortho G G G G G G G Il7r Gnb2l1 ortho G G G G G G G G G Gnb2l1 Cct2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikbkg Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rictor ortho P Dynll1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rpl10 ortho P Gnb2l1 Ak2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Insr Gnb2l1 ortho P G G Vhl Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Agtr1a Gnb2l1 ortho Fn1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Actb Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pcbp2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Elovl4 ortho G G G G G G G Gnb2l1 Cct3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pbx1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Kcna5 ortho G G G G G G G G G G G G Gnb2l1 Tsc22d4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Nol6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ifnar2 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Larp4 ortho P Gnb2l1 Ttyh3 ortho Gnb2l1 Yipf5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Sgtb ortho G G G G G G G G G G G G G G G Ercc2 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Grpel1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pik3cd Gnb2l1 ortho G G G G G G G G G G G G G G G G G G Gnb2l1 Eif3k ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdh1 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rps5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnf Gnb2l1 ortho Gnb2l1 Protein Zcchc3, Zinc finger, CCHC domain containing 3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pgm2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Birc2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Rasa3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arf4 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Slc4a2 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 St7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ache Gnb2l1 ortho GP G G G G G G G G G G G G Cd81 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Fubp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl37a Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pabpc1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Nol10 ortho P Rpsa Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Itgb2 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Sirt7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Suz12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Xpo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Mapk3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Acat1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Nob1 ortho P Gnb2l1 Pir ortho P Itgb7 Gnb2l1 ortho G G G G G G G G G Map3k4 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps27a Gnb2l1 ortho P Rps12 Gnb2l1 ortho P Bcl2l11 Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Cish ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Mkrn2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Helz ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Fbxw7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Sbds ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps18 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Pag1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Stk3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Eif3g ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nfatc1 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G Cdkn1a Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stx1a Gnb2l1 ortho G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Larp4b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Atl2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Ezh2 ortho G G G G G G G G G G G G G G G G G G G G G G G Rplp0 Gnb2l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Habp4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Bag2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P12931 P68040 - 9584165 - X 2 P12931 P68040 - 9584165 - X 2 P12931 P68040 - 9584165 - X 2 P68040 Q60751 - 11884618 - X 2 P68040 P62871 two hybrid 12359736 direct interaction X 2 P68040 P62871 pull down 12359736 direct interaction X 2 P68040 affinity chromatography technology 20697350 physical association X 2 P68040 A0A024R730 affinity chromatography technology 17110338 physical association X 2 P68040 P54727 affinity chromatography technology 23649778 physical association X 2 P68040 P54787 affinity chromatography technology 23649778 physical association X 2 P68040 Q921E6 affinity chromatography technology 24457600 physical association X 2 P48510 P68040 affinity chromatography technology 23649778 physical association X 2 P68040 P62874 affinity chromatography technology 12359736 physical association X 2 P68040 Q13501 affinity chromatography technology 23649778 physical association X 2 P68040 A0A024R284 affinity chromatography technology 23649778 physical association X 2 P68040 affinity chromatography technology 17500595 physical association X 2 P68040 cosedimentation 16615898 colocalization C 1216 P68040 affinity chromatography technology 16635246 association C 94 P68040 anti bait coimmunoprecipitation 16635246 association C 96 P68040 affinity chromatography technology 16635246 association C 83 P68040 pull down 20697350 association C 4 P68040 O88351 two hybrid 15102471 physical association X 2 P68040 O88351 two hybrid 15102471 physical association X 2 P68040 O88351 two hybrid 15102471 physical association X 2 P68040 O88351 two hybrid 15102471 physical association X 2 P68040 Q8C5D8 two hybrid pooling approach 22210188 physical association X 2 P68040 Q8C5D8 fluorescence microscopy 22210188 colocalization X 2 P68040 Q8C5D8 two hybrid 22210188 physical association X 2 P68040 Q80V81 two hybrid 22674187 physical association X 2 P22303 P68040 anti bait coimmunoprecipitation 18194455 physical association X 2 Q9CQT7 P68040 two hybrid pooling approach 22370726 physical association X 2 P68040 anti bait coimmunoprecipitation 18194455 association C 3 P68040 blue native page 17205597 physical association C 9 P68040 affinity chromatography technology 15627969 association C 11 P68040 Q99LX0 anti bait coimmunoprecipitation 24947010 physical association X 2 P68040 Q99LX0 confocal microscopy 24947010 colocalization X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Nedd9 Gnb2l1 MI:0096(pull down)|MI:0096(pull down)|MI:0096(pull down)|MI:0004(affinity chromatography technology) 20697350 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0914(association)|MI:0915(physical association) (intact)|(intact)|(intact)|(biogrid) UniProt_185047|UniProt_172906|UniProt_108797|BIOGRID_322869 bait|bait|bait|bait prey|prey|prey|prey Gnb2l1 Tp73 MI:0018(two hybrid)|MI:0018(two hybrid) 18194455 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association) (intact)|(intact) UniProt_168043|UniProt_92749 bait|bait null|null Gnb1 Gnb2l1 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0096(pull down)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 12359736,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact)|(biogrid)|(intact)|(intact)|(intact)|(intact)|(intact)|(intact) UniProt_167131|UniProt_167121|UniProt_167132|UniProt_167117|UniProt_167133|UniProt_167136|UniProt_167123|UniProt_167119|BIOGRID_322649|UniProt_167134|UniProt_167124|UniProt_167128|UniProt_167115|UniProt_167135|UniProt_167116 neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|bait|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component|prey|neutral component|neutral component|neutral component|neutral component|neutral component|neutral component Gnb2l1 Pias2 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 22210188 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact) UniProt_175541|UniProt_175538|UniProt_122023|UniProt_175539 neutral component|prey|neutral component|prey neutral component|bait|neutral component|bait Gnb2l1 Eed MI:0027(cosedimentation)|MI:0004(affinity chromatography technology) 16615898,24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association) (intact)|(biogrid) UniProt_167137|BIOGRID_332176 neutral component|prey neutral component|bait Gnb2l1 Zfp819 MI:0018(two hybrid) 22674187 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_174015 prey bait Htt Gnb2l1 MI:0027(cosedimentation)|MI:0004(affinity chromatography technology)|MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0027(cosedimentation) 16615898,17500595 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0403(colocalization) (intact)|(biogrid)|(intact)|(intact)|(intact) UniProt_167131|BIOGRID_323672|UniProt_167130|UniProt_167116|UniProt_167114 neutral component|bait|neutral component|neutral component|neutral component neutral component|prey|neutral component|neutral component|neutral component Gnb2l1 Desi1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 22370726 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (intact)|(intact) UniProt_175272|UniProt_123154 prey|prey bait|bait Ikbkb Gnb2l1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact) UniProt_163244|UniProt_162624|UniProt_164828|UniProt_164829 bait|bait|bait|bait prey|prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality BMPR2 RACK1 17515463,17515463,17515463 0096,0018,0007 LC IKBKB RACK1 15102471 0018 LC ITGB1 RACK1 15611085 0019 LC PTPN11 RACK1 15611085 0019 LC IRS1 RACK1 15611085 0019 LC YWHAE RACK1 16615898 0027 LC YWHAZ RACK1 16615898 0027 LC RACK1 ACTA1 17205597 0276 LC RACK1 YWHAH 21311561 0030 LC RACK1 IGF1R 11884618 0019 LC RACK1 HSD3B4 16615898 0027 LC RACK1 PIAS2 22210188,22210188,22210188 0416,0398,0018 LC RACK1 PGLS 16615898 0027 LC RACK1 DESI1 22370726 0398 LC RACK1 ZFP819 22674187 0018 LC RACK1 HSD3B7 16615898 0027 LC NEDD9 RACK1 20697350,20697350 0004,0096 LC BMPR2 RACK1 17515463,17515463,17515463 0096,0018,0007 LC ALDOA RACK1 15627969 0004 LC UBC RACK1 23649778 0004 LC RAB19 RACK1 26885862 0676 LC GRIN1 RACK1 16635246,16635246 0004,0006 HT GNB1 RACK1 12359736 0004 LC RACK1 GRIN2B 16635246 0004 HT RACK1 RPGRIP1L 21565611 0007 HT RACK1 EED 24457600 0004 LC RACK1 PARK7 24947010,24947010 0006,0663 LC RACK1 RAB32 26885862 0676 LC RACK1 DLGAP1 27507650 0004 LC RACK1 TP73 18194455 0006 LC RACK1 TYK2 15240704 0007 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q61767 P68040 HSD3B4 GNB2L1 0.081 16615898 Q8CG73 P68040 RPGRIP1L GNB2L1 0.126 21565611 P68040 P62259 GNB2L1 YWHAE 0.081 16615898 P68040 P0CG50 GNB2L1 UBC 0.126 23649778 Q8BL48 P68040 UNK GNB2L1 0.126 25737280 P68040 P13569 GNB2L1 CFTR 0.126 17110338 P68040 P05064 GNB2L1 ALDOA 0.21 15627969 P68040 P35438 GNB2L1 GRIN1 0.236 16635246 P68040 P62871 GNB2L1 GNB1 0.523 12359736 P68040 O35177 GNB2L1 NEDD9 0.332 20697350 Q921E6 P68040 EED GNB2L1 0.126 24457600 Q99LX0 P68040 PARK7 GNB2L1 0.309 24947010 P68040 P35294 GNB2L1 RAB19 0.126 26885862 Q9CQ60 P68040 PGLS GNB2L1 0.081 16615898 Q9CQT7 P68040 DESI1 GNB2L1 0.21 22370726 Q9CZE3 P68040 RAB32 GNB2L1 0.126 26885862 Q9D415 P68040 DLGAP1 GNB2L1 0.126 27507650 Q9EQC1 P68040 HSD3B7 GNB2L1 0.081 16615898 Q8C5D8 P68040 PIAS2 GNB2L1 0.523 22210188 P68040 O88351 GNB2L1 IKBKB 0.183 15102471 P68510 P68040 YWHAH GNB2L1 0.126 21311561 Q9JJP2 P68040 TP73 GNB2L1 0.21 18194455 P68134 P68040 ACTA1 GNB2L1 0.126 17205597 P68040 P62874 GNB2L1 GNB1 0.21 12359736 P68040 P63101 GNB2L1 YWHAZ 0.081 16615898 Q01097 P68040 GRIN2B GNB2L1 0.126 16635246 P68040 P22303 GNB2L1 ACHE 0.21 18194455