PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ube2b Hist2h2bb 11929833 biogrid exp P G Ube2b Unk 25737280 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Rad18 17720710,12509447 biogrid exp, ortho G G G G G G G Ube2b Dstn ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Hist2h2ac ortho P Ube2b Ubr2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Rnf40 ortho P Ube2b Nipsnap3b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Uba2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ubr3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ube2c ortho G G G G G G G G G G G G G G G G G G Ube2b Zyx ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Igbp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ttc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ctnnb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Ube2b ortho G G G G G G G G G G G G G Ube2b Ube2v2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ercc4 ortho G G G G G G G G G G G G G G G G G G G Ube2b Hist3h2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Crmp1 ortho P G G G G G G G G G G Ube2b Ankrd32 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Fbp1 ortho GP G G G G G G G G G G G G G G G G G Ube2b Srxn1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mocs3 Ube2b ortho P Ube2b Cct2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ubqln1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rtf1 Ube2b ortho P Mdm2 Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Zmym2 ortho P Ube2b Nbn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nipsnap1 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Cplx1 Ube2b ortho P G G G G G G G G G G G G G G G G G G G G Ube2b Ube2l3 ortho P Polr2a Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Abhd10 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr4 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Sec23a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Usp9x ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Hltf ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Kcmf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Serpinh1 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Psmb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cnbp Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ube2v1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ssbp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Wdr61 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr1 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tyms Ube2b ortho G G Ube2b Skp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Sec24a ortho P Ube2b Ddx55 ortho Ube2b Birc2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Wdr82 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Srsf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ahcyl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Irf7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ube2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ube2i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Unc119 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Xrcc6 Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Atp6v1f ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Uba1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Cnot4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmb8 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Med31 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ubqln4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Wac ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ctr9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ubxn7 ortho P Ube2b Sars2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Trim45 ortho Ube2b Ubr5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sssca1 Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Cdc73 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcna Ube2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b ATPase, H+ transporting, lysosomal V1 subunit B1, ATPase, H+ transporting, lysosomal V1 subunit B1, isoform CRA_a, Protein Atp6v1b1, Vacuolar proton translocating ATPase B1 isoform ortho P G G G G Ube2b Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn1b Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Polh ortho Ube2b Paics ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Ttll12 ortho P Ube2b Cbx5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Vcp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Zfyve19 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pex2 Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Prdx5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2b Leo1 ortho P Ube2d1 Ube2b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P63147 affinity chromatography technology 12509447 physical association X 2 P63147 affinity chromatography technology 12509447 physical association X 2 P63147 pull down 17720710 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ube2b Rad18 MI:0401(biochemical)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 12509447,17720710 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_319742|BIOGRID_329076|BIOGRID_329074 prey|prey|bait bait|bait|prey

PPI - HINT Gene A Gene B PMID Method Quality UBE2B HIST2H2BB 11929833 0415 LC UBE2B RAD18 17720710,12509447 0096,0004 LC