PTM - dbPAF Gene Name UniProt ID Position Type Species Map3k3; Mekk3 Q61084 129 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 130 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 131 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 145 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 147 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 153 T Mus musculus(Mouse) Map3k3; Mekk3 Q61084 155 Y Mus musculus(Mouse) Map3k3; Mekk3 Q61084 166 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 168 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 169 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 175 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 176 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 237 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 239 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 250 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 274 T Mus musculus(Mouse) Map3k3; Mekk3 Q61084 311 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 312 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 314 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 316 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 317 T Mus musculus(Mouse) Map3k3; Mekk3 Q61084 337 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 340 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 355 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 357 S Mus musculus(Mouse) Map3k3; Mekk3 Q61084 526 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q61084 R249-m1 Methylation KSQMSRArsFPDNrK Q61084 R255-m1 Methylation ArsFPDNrKECSDRE Q61084 S131-p Phosphorylation DRNHTSSsPHSGVSR Q61084 S145-p Phosphorylation RQVRIKPsQsAGDIN Q61084 S147-p Phosphorylation VRIKPsQsAGDINtI Q61084 T153-p Phosphorylation QsAGDINtIyQAPEP Q61084 Y155-p Phosphorylation AGDINtIyQAPEPRS Q61084 S166-p Phosphorylation EPRSRHLsVsSQNPG Q61084 S168-p Phosphorylation RSRHLsVsSQNPGRs Q61084 S175-p Phosphorylation sSQNPGRssPPPGYV Q61084 S176-p Phosphorylation SQNPGRssPPPGYVP Q61084 S237-p Phosphorylation SLDRSADsPSFRKSQ Q61084 S250-p Phosphorylation SQMSRArsFPDNrKE Q61084 T274-p Phosphorylation DKGVKGGtYPRRYHV Q61084 T294-p Phosphorylation DYNDGRRtFPRIRRH Q61084 S312-p Phosphorylation LFTLVPSsRSLStNG Q61084 T317-p Phosphorylation PSsRSLStNGENMGV Q61084 S337-p Phosphorylation DPRGRLRsADsENAL Q61084 S340-p Phosphorylation GRLRsADsENALTVQ Q61084 S355-p Phosphorylation ERNVPTKsPsAPINW Q61084 S357-p Phosphorylation NVPTKsPsAPINWRR Q61084 S526-p Phosphorylation MSGTGIRsVTGTPYW

PTM - dbPTM UniProt ID Position Code Type Resources References Q61084 166 S Phosphorylation Swiss-Prot 1010711 19367708 Q61084 337 S Phosphorylation Swiss-Prot 1010711 17242355 Q61084 340 S Phosphorylation Swiss-Prot 1010711 17242355 Q61084 337 S Phosphorylation PhosphoELM.10011 17242355 Q61084 340 S Phosphorylation PhosphoELM.10011 17242355 Q61084 526 S Phosphorylation PhosphoELM.10011 16407301 Q61084 147 S Phosphorylation Phosphositeplus.1010730 20531401;21183079 Q61084 166 S Phosphorylation Phosphositeplus.1010730 18846507;19367708;20531401;21183079 Q61084 176 S Phosphorylation Phosphositeplus.1010730 21183079 Q61084 237 S Phosphorylation Phosphositeplus.1010730 21183079 Q61084 337 S Phosphorylation Phosphositeplus.1010730 17242355;20531401;21183079;21659604 Q61084 340 S Phosphorylation Phosphositeplus.1010730 17242355;19367708;19854140;20531401;21183079;21659604;21659605 Q61084 355 S Phosphorylation Phosphositeplus.1010730 20531401 Q61084 166 S Phosphorylation SysPTM 1.1 18846507 Q61084 175 S Phosphorylation SysPTM 1.1 18846507 Q61084 337 S Phosphorylation SysPTM 1.1 17242355 Q61084 340 S Phosphorylation SysPTM 1.1 17242355

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q61084 526 S 16407301 LTP Phosphorylation Q61084 340 S 17242355 HTP Phosphorylation Q61084 337 S 17242355 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q61084 147 Phosphoserine 21183079 Q61084 166 Phosphoserine 21183079 Q61084 337 Phosphoserine; by SGK1 17242355;21183079 Q61084 340 Phosphoserine 17242355;21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Map3k3 IPI00117089 S 145 QVRIKPpSQSAGDI phosphorylation Map3k3 IPI00117089 S 147 RIKPSQpSAGDINT phosphorylation Map3k3 IPI00117089 S 166 PRSRHLpSVSSQNP phosphorylation Map3k3 IPI00117089 S 239 RSADSPpSFRKSQM phosphorylation Map3k3 IPI00117089 S 311 LFTLVPpSSRSLST phosphorylation Map3k3 IPI00117089 S 337 PRGRLRpSADSENA phosphorylation Map3k3 IPI00117089 S 340 RLRSADpSENALTV phosphorylation Map3k3 IPI00117089 S 355 RNVPTKpSPSAPIN phosphorylation

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 26406 204959 - K Ubiquitination 19843958