PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Rims1 Fbxl20 17803915 biogrid,intact exp Syp Fbxl20 17803915 intact exp G G G G G G G G G G G G Fbxl20 Skp1 17803915 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbxl20 Cul1 17803915 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vcp Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahcy Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cfl2 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbxl20 Smpx ortho G G G G G G G G G G G G G G G Dlat Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pfkl Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbxl20 Nprl2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aldh1b1 Fbxl20 ortho G G G G G G G G G G H2afv Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gpi Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Col7a1 Fbxl20 ortho G G G G G G G G G G G G G G Cct8 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vdac2 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppif Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk2 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Gch1 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G Fbxl20 Pfkp ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2r2 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rad23b Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct3 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif2b5 Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q9CZV8 Q9WTX5 affinity chromatography technology 17803915 physical association X 2 Q9CZV8 Q9WTX6 affinity chromatography technology 17803915 physical association X 2 Q9CZV8 P0CG48 affinity chromatography technology 17803915 physical association X 2 Q9CZV8 Q99NE5-5 affinity chromatography technology 17803915 physical association X 2 Q9CZV8 anti tag coimmunoprecipitation 17803915 association C 3 Q9CZV8 coimmunoprecipitation 17803915 association C 3 Q9CZV8 anti bait coimmunoprecipitation 17803915 association C 3 Q9CZV8 Q99NE5 pull down 17803915 physical association X 2 Q9CZV8 Q99NE5 pull down 17803915 physical association X 2 Q9CZV8 P0CG47 anti tag coimmunoprecipitation 17803915 physical association X 2 Q9CZV8 Q99NE5 anti bait coimmunoprecipitation 17803915 physical association X 2 Q9CZV8 Q62277 fluorescence microscopy 17803915 colocalization X 2 Q9CZV8 Q99NE5 fluorescence microscopy 17803915 colocalization X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Rims1 Fbxl20 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17803915 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (intact)|(intact)|(intact)|(intact)|(biogrid) UniProt_168640|UniProt_168635|UniProt_168639|UniProt_168638|BIOGRID_316019 bait|prey|prey|neutral component|prey prey|bait|bait|neutral component|bait Syp Fbxl20 MI:0007(anti tag coimmunoprecipitation) 17803915 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization) (intact) UniProt_168637 neutral component neutral component Fbxl20 Skp1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17803915 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_168634|BIOGRID_316016 bait|bait prey|prey Fbxl20 Cul1 MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology) 17803915 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_168634|BIOGRID_316017 bait|bait prey|prey

PPI - HINT Gene A Gene B PMID Method Quality SYP FBXL20 17803915 0416 LC RIMS1 FBXL20 17803915,17803915,17803915,17803915,17803915 0415,0416,0006,0004,0096 LC RIMS1 FBXL20 17803915,17803915,17803915,17803915,17803915 0415,0416,0006,0004,0096 LC FBXL20 SKP1 17803915,17803915 0006,0004 LC FBXL20 CUL1 17803915,17803915 0006,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9CZV8 Q62277 FBXL20 SYP 0.126 17803915 Q9WTX6 Q9CZV8 CUL1 FBXL20 0.376 17803915 Q9WTX5 Q9CZV8 SKP1 FBXL20 0.376 17803915 Q9CZV8 Q99NE5 FBXL20 RIMS1 0.765 17803915 Q9CZV8 P0CG47 FBXL20 UBB 0.21 17803915 Q9CZV8 P0CG48 FBXL20 UBC 0.21 17803915