PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhah Atg3 21311561 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map1lc3a Atg3 18083104,19838173 innatedb,biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Atg12 24191030,20723759 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Atg7 24191030,22055190,22170151 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg5 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cflar Atg3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa9 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Bag3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Slx4ip ortho Rpl23 Atg3 ortho P Xpo1 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gtf2f2 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Map1lc3b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Map1b Atg3 ortho GP G G G G G G G G G G G G G G G G G G Crebbp Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tecpr1 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabarapl1 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G N-acetylneuraminic acid synthase (Sialic acid synthase), Protein Nans Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ambra1 Atg3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfaip8 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Atg4b Atg3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ass1 Atg3 ortho P G G G G G G G G G G G G G G G G G G G G G G G G G Atg10 Atg3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Atg16l1 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nhlrc2 Atg3 ortho P Dffa Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg3 Gabarap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabarapl2 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Becn1 Atg3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants O94817 Q9CPX6 affinity chromatography technology 20723759 physical association X 2 O94817 Q9CPX6 affinity chromatography technology 23202584 physical association X 2 Q9CQY1 Q9CPX6 affinity chromatography technology 24191030 physical association X 2 Q9CPX6 Q91VR7 affinity chromatography technology 18083104 physical association X 2 Q9CPX6 Q9D906 affinity chromatography technology 22170151 physical association X 2 Q9CPX6 Q9D906 affinity chromatography technology 22170151 physical association X 2 Q9CPX6 Q9D906 pull down 22055190 direct interaction X 2 Q9CPX6 Q9D906 affinity chromatography technology 24191030 physical association X 2 O94817 Q9CPX6 anti tag coimmunoprecipitation 23202584 physical association X 2 Q9CQY1 Q9CPX6 anti tag coimmunoprecipitation 20723759 physical association X 2 Q9CQY1 Q9CPX6 anti tag coimmunoprecipitation 20723759 physical association X 2 Q9CQY1 Q9CPX6 anti bait coimmunoprecipitation 20723759 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Atg3 Atg12 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20723759,24191030 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|(intact)|(intact) BIOGRID_331704|UniProt_172808|UniProt_172805|UniProt_172804 bait|bait|prey|prey prey|prey|bait|bait Map1lc3a Atg3 MI:0004(affinity chromatography technology) 18083104 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321613 bait prey

PPI - HINT Gene A Gene B PMID Method Quality YWHAH ATG3 21311561 0030 LC ATG3 PGLS 16615898 0027 LC MAP1LC3A ATG3 19838173,18083104 0007,0004 LC ATG3 ATG12 20723759,20723759,24191030 0006,0007,0004 LC ATG3 ATG7 22055190,22170151,24191030 0096,0004,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9D906 Q9CPX6 ATG7 ATG3 0.659 24191030,22170151,22055190 Q9CPX6 Q91VR7 ATG3 MAP1LC3A 0.21 18083104 Q9CPX6 O94817 ATG3 ATG12 0.569 23202584,20723759 Q9CQ60 Q9CPX6 PGLS ATG3 0.081 16615898 Q9CQY1 Q9CPX6 ATG12 ATG3 0.507 20723759,24191030 Q9CPX6 P68510 ATG3 YWHAH 0.126 21311561