PTM - CPLM Gene Name UniProt ID Type Position Code Cul2 Q9D4H8 Ubiquitination 16 K Cul2 Q9D4H8 Ubiquitination 114 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Cul2 Q9D4H8 284 S Mus musculus(Mouse) Cul2 Q9D4H8 394 Y Mus musculus(Mouse) Cul2 Q9D4H8 602 S Mus musculus(Mouse) Cul2 Q9D4H8 603 T Mus musculus(Mouse) Cul2 Q9D4H8 616 S Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9D4H8 K382-ac Acetylation VVNYREPkSVCKAPE Q9D4H8 K393-ac Acetylation KAPELLAkyCDNLLK Q9D4H8 S284-p Phosphorylation FLHSECHsIIQQERk Q9D4H8 Y394-p Phosphorylation APELLAkyCDNLLKK Q9D4H8 S616-p Phosphorylation ELTKTIKsLLDVKMI Q9D4H8 K16-ub Ubiquitination DFDETWNkLLTTIKA Q9D4H8 K114-ub Ubiquitination YLNTQYIkKNKLTEA Q9D4H8 K238-ub Ubiquitination NCSQYMEkVLGRLKD Q9D4H8 K291-ub Ubiquitination sIIQQERkNDMANMY Q9D4H8 K382-ub Ubiquitination VVNYREPkSVCKAPE Q9D4H8 K393-ub Ubiquitination KAPELLAkyCDNLLK Q9D4H8 K428-ub Ubiquitination VFKYIDDkDVFQkFY Q9D4H8 K433-ub Ubiquitination DDkDVFQkFYARMLA Q9D4H8 K608-ub Ubiquitination DSTQMNEkELTKTIK

PTM - dbPTM UniProt ID Position Code Type Resources References Q9D4H8 284 S Phosphorylation Swiss-Prot 1010711 17203969 Q9D4H8 394 Y Phosphorylation Swiss-Prot 1010711 17203969 Q9D4H8 284 S Phosphorylation PhosphoELM.10011 17203969 Q9D4H8 394 Y Phosphorylation PhosphoELM.10011 17203969 Q9D4H8 284 S Phosphorylation Phosphositeplus.1010730 17203969 Q9D4H8 616 S Phosphorylation Phosphositeplus.1010730 21659604 Q9D4H8 394 Y Phosphorylation Phosphositeplus.1010730 17203969 Q9D4H8 270 M Oxidation SysPTM 1.1 17203969 Q9D4H8 284 S Phosphorylation SysPTM 1.1 17203969 Q9D4H8 394 Y Phosphorylation SysPTM 1.1 17203969

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9D4H8 394 Y 17203969 HTP Phosphorylation Q9D4H8 284 S 17203969 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9D4H8 393 N6-acetyllysine 23806337

PTM - BioGRID Entrez Gene BioGRID ID Position Code Type PMIDs 71745 214895 - K Neddylation 24452456

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Cul2 Mus musculus (Mouse) 117; 385; 396; 436; 611; 294; 241; 19; 431 "117,LNTQYIKKNKLTE; 385,VNYREPKSVCKAP; 396,APELLAKYCDNLL; 436,DKDVFQKFYARML; 611,STQMNEKELTKTI; 294,IIQQERKNDMANM; 241,CSQYMEKVLGRLK; 19,FDETWNKLLTTIK; 431,FKYIDDKDVFQKF" 117:22790023; 385:22790023; 396:22790023; 436:22790023; 611:22790023; 294:22790023; 241:22790023; 19:22790023; 431:22790023