PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ddb1 Iqcb1 21565611 biogrid,intact exp Pou5f1 Ddb1 20362542 biogrid,intact exp Ddb1 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Ddb1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hmga2 Ddb1 26045162 intact exp G G G G Ddb1 Elf5 26584622 biogrid exp G G G G G Ddb1 Rpgrip1l 21565611 intact exp Ddb1 Trpm7 24855944 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ddb2 12107171 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Eed 24457600 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Ddb1 17967871 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lmo4 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cul1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rpa2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cep72 ortho Ddb1 Ip6k1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myb Ddb1 ortho G G G G G G G G G G G G G G G Ddb1 Cmas ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Tubgcp2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cops7b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Brwd1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pold1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G Ddb1 Ercc4 ortho G G G G G G G G G G G G G G G G G G G Arid4b Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hoxd3 Ddb1 ortho G G G G G Ung Ddb1 ortho G G G G G G G G G G G G G G G G G G G G Ddb1 Ddhd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Tet2 ortho Wsb2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ezh2 ortho G G G G G G G G G G G G G G G G G G G G G G G Map3k1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Sirt6 Ddb1 ortho Ddb1 Kcnd3 ortho Ddb1 Rptor ortho P Ddb1 Ddit4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myc Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G Cops6 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 LRWD1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Clic1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Clic4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Suz12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cops8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Mtor ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Sall2 ortho G G G G G G G G G G G G G Ddb1 Rbbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Snw1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ercc8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Grk5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dda1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Wdr5b ortho Ddb1 Cnot2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Bcar3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Uba1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Crbn ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Snrnp40 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Tcerg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Jarid2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dcaf13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Invs Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G Ddb1 Asb4 ortho G G G G G G G G Hdac2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Kdm4a ortho Ddb1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dlc1 ortho G G Wdr5 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Becn1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Clcn1 ortho G G Nedd8 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vamp3 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Acat1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Polr2j Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cand1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Grk6 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Protein Taf15, TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor ortho P Ddb1 Det1 ortho Ddb1 Mus81 ortho G G G G G G G G G G G G G G G G G G G G Ddb1 Uvssa ortho Ddb1 Ubxn7 ortho P Ddb1 Cul3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cenpa Ddb1 ortho G G G G G G G G G G G G G G G G G G G Setd8 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Topbp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Mib1 ortho P G G G G G G G G G Ddb1 Tada2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Grwd1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cggbp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Gps1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ranbp9 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Egfr Ddb1 ortho GP G G G G G G G G G G G G G G G G G Ddb1 Numa1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nf2 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Abl1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup43 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Sap30 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rps6kb2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Uchl1 ortho P G G G G G G G G G G G G G G G G G G Ddb1 Suds3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Slx4 ortho Ddb1 Fbxo44 ortho Ddb1 Rassf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbp1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Htt Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Pin1 ortho P Pten Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Chek1 Ddb1 ortho G G G G G G G G G G G G G G G Hoxb4 Ddb1 ortho G G G G G G Ddb1 Rbbp5 ortho Ddb1 Dclre1c ortho Polr2a Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rgs2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Puf60 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Zfp277 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aurkb Ddb1 ortho G G G G G G G G G G G G G Nr1i2 Ddb1 ortho G G G G G Ddb1 Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Terf2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dcaf17 Ddb1 ortho Ddb1 Fbxw5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Banf1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G E2f3 Ddb1 ortho G G G G G Pcna Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Btrc ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Med19 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Trpc4ap ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ubr5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Apex1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sap30bp Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rfwd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Strn4 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Ercc6 Ddb1 ortho Ddb1 Prkab1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Gstk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Wdtc1 ortho G G G G G G G G G G G G G G G G G G G G G G G Mcm10 Ddb1 ortho G G G G G G G G G G G G G Ddb1 Fzr1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rassf10 ortho Ddb1 Rad21 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vtn Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G Ddb1 Pwp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Samhd1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Gabarap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dyrk2 ortho Rag2 Ddb1 ortho Ddb1 Tet3 ortho Tsc22d1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ago2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lsm2 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dcaf6 ortho Tnfrsf1b Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G Ddb1 Fbxw8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vasp Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ubxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Srsf9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dcaf8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mafb Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Mcm5 Ddb1 ortho P G G G G G G G G G G G G G G Ddb1 Dcaf5 ortho P G G G G G G G G G G Ddb1 Dcaf12 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhaz Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Gabarapl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 E2f1 ortho G G G G G Esr2 Ddb1 ortho G Pms2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dcaf11 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cep57 ortho Ube2e3 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Nudcd3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ilk Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Vprbp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ino80 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Tle2 ortho P G G G G G G G G G G G G G G G G G G Ddb1 Gpn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rbbp7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Hdac5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nr2c2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Nhp2l1 ortho P Ddb1 Actr5 ortho Ddb1 Sf3a3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Katna1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dtl Ddb1 ortho G G G G G G G G G G G Ddb1 Phf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Coro1b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cdc5l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops5 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plk1 Ddb1 ortho G G G G G G G G G G G G G G Hnrnpk Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Ddb1 ortho G G G G G G G G G G G G G Ddb1 Flnc ortho GP G G G G G G G G G G Ddb1 Rpa3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Atp6v1f ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Sirt7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Lasp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Tor1aip2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ftsj3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Dcaf10 Ddb1 ortho Shc1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Xpa ortho G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Nup133 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul4a Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Babam1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Usp40 ortho Ddb1 Tet1 ortho G Ddb1 Tp73 ortho G Ddb1 Wdr21 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ambra1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dcaf7 Ddb1 ortho Ddb1 Rassf9 ortho G Ddb1 Psma1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul4b Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rag1 Ddb1 ortho G G G Alb Ddb1 ortho GP G G G G G G G G G G G G G G G G G G Ddb1 Cstf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikbkg Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops4 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cdkn2a ortho Ddb1 Eme1 ortho G G G Ercc1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h1c Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Brap ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Lrrk2 ortho GP G G G G G G G G G G G G G G G G G G G G Cdkn1b Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Sin3a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Protein Supt3, Suppressor of Ty 3 homolog (S. cerevisiae), isoform CRA_a ortho Ddb1 Mapk3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ptpn14 ortho G Rps7 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahr Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctnnb1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rps9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rpa1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dcun1d1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Apc ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wsb1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Ddb1 ortho P G G G G Faf2 Ddb1 ortho P Ddb1 Epb41l3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Mbd3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nphp4 Ddb1 ortho Ddb1 Snx2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cdt1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Yars ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cep250 ortho Hdac1 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Rictor ortho P Ddb1 Strip1 ortho P Ddb1 Dyrk1b ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Recql ortho G G G G G G G G G G G G G G G G G G G G G Ddb1 Wdr26 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Dcaf15 ortho G G G G G G G G G G G G G G G G G G G G G Ddb1 Mef2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Skp2 ortho G G G G G G G G G G G G G Ddb1 Ncoa5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ep300 Ddb1 ortho P Cops3 Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tpr Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn1a Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aurka Ddb1 ortho G G G G G G G G G G G G G G Ddb1 Map3k3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Kat2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Cul5 ortho P Ddb1 Cul7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Tert Ddb1 ortho Ddb1 Cops7a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xpc Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lin7c Ddb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Sap130 ortho Terf1 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Rora Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Camkk1 ortho G G G G G G G G G G G G G G G Ddb1 Ntrk1 ortho Traf6 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G Ddb1 Pidd1 ortho G G G G G Ddb1 Phip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Ago1 ortho P Ddb1 Rtn4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mdm2 Ddb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q3U1J4 affinity chromatography technology 20362542 physical association X 2 Q66K64 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q549C9 Q3U1J4 affinity chromatography technology 17967871 physical association X 2 Q5TAQ9 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q5QP82 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q99J79 Q3U1J4 affinity chromatography technology 12107171 physical association X 2 Q9UBW8 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 A0A024R7W9 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q59FK4 two hybrid 12107171 direct interaction X 2 Q3U1J4 Q59FK4 pull down 12107171 direct interaction X 2 Q3U1J4 Q59FK4 affinity chromatography technology 12107171 physical association X 2 Q3U1J4 Q9BW61 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q13620-3 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q5T6F0 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q15293 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q13216 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 B2RBV7 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q7L5N1 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q9Y4B6-3 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q9UNS2 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q58WW2-3 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 O43175 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q9NXF7 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q9Y266 affinity chromatography technology 20360068 physical association X 2 Q9C0C7-4 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 O75459 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 A0A024R471 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q92466 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q8BP00 Q3U1J4 affinity chromatography technology 21565611 physical association X 2 Q8N5D0-4 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q921E6 affinity chromatography technology 24457600 physical association X 2 Q3U1J4 Q16531 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q13098-5 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q8TEL6-3 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q9BT78 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 Q8TEB1 affinity chromatography technology 20360068 physical association X 2 Q3U1J4 cosedimentation 16615898 colocalization C 1216 Q3U1J4 tandem affinity purification 20362542 association C 94 Q3U1J4 tandem affinity purification 20360068 physical association C 32 Q3U1J4 anti tag coimmunoprecipitation 21565611 association C 48

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Pou5f1 Ddb1 MI:0004(affinity chromatography technology)|MI:0676(tandem affinity purification) 20362542 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association) (biogrid)|(intact) BIOGRID_314377|UniProt_170860 bait|bait prey|prey Ddb1 Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332417 prey bait Tp53 Ddb1 MI:0004(affinity chromatography technology) 17967871 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_312357 prey bait Ddb1 Iqcb1 MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 21565611 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0914(association)|MI:0915(physical association)|MI:0914(association)|MI:0914(association) (intact)|(intact)|(biogrid)|(intact)|(intact) UniProt_113735|UniProt_172315|BIOGRID_326764|UniProt_113729|UniProt_172309 prey|prey|prey|prey|prey bait|bait|bait|bait|bait Ddb1 Ddb2 MI:0004(affinity chromatography technology) 12107171 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322710 bait prey

PPI - HINT Gene A Gene B PMID Method Quality YWHAE DDB1 16615898 0027 LC DDB1 PGLS 16615898 0027 LC TP53 DDB1 17967871 0004 LC POU5F1 DDB1 20362542,20362542 0676,0004 LC HMGA2 DDB1 26045162 0096 LC DDB1 IQCB1 21565611,21565611 0004,0007 HT DDB1 RPGRIP1L 21565611 0007 HT DDB1 ELF5 26584622 0004 LC DDB1 EED 24457600 0004 LC DDB1 TRPM7 24855944,24855944 0006,0007 LC DDB1 DDB2 12107171 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q3U1J4 P22682 DDB1 CBL 0.126 27474268 Q8CG73 Q3U1J4 RPGRIP1L DDB1 0.126 21565611 Q3U1J4 P62259 DDB1 YWHAE 0.081 16615898 Q8VDK3 Q3U1J4 ELF5 DDB1 0.126 26584622 Q923J1 Q3U1J4 TRPM7 DDB1 0.236 24855944 Q3U1J4 P20263 DDB1 POU5F1 0.236 20362542 Q3U1J4 P22695 DDB1 UQCRC2 0.236 26496610 Q3U1J4 P02538 DDB1 KRT6A 0.236 26496610 Q3U1J4 P00491 DDB1 PNP 0.236 26496610 Q3U1J4 O75459 DDB1 PAGE1 0.236 20360068 Q3U1J4 O60547 DDB1 GMDS 0.236 26496610 Q3U1J4 O60293 DDB1 ZFC3H1 0.236 26496610 Q3U1J4 O43175 DDB1 PHGDH 0.236 20360068 Q96SW2 Q3U1J4 CRBN DDB1 0.236 20360068 Q3U1J4 Q13216 DDB1 ERCC8 0.236 20360068 Q3U1J4 P62877 DDB1 RBX1 0.236 26496610 Q3U1J4 P52292 DDB1 KPNA2 0.236 26496610 Q3U1J4 P62995 DDB1 TRA2B 0.236 26496610 Q3U1J4 Q08554 DDB1 DSC1 0.236 26496610 Q5D862 Q3U1J4 FLG2 DDB1 0.236 26496610 Q3U1J4 Q14978 DDB1 NOLC1 0.236 26496610 Q3U1J4 Q15293 DDB1 RCN1 0.236 20360068 Q3U1J4 Q16531 DDB1 DDB1 0.236 20360068 Q92905 Q3U1J4 COPS5 DDB1 0.236 20360068 Q8N5D0 Q3U1J4 WDTC1 DDB1 0.236 20360068 Q66K64 Q3U1J4 DCAF15 DDB1 0.236 20360068 Q5TAQ9 Q3U1J4 DCAF8 DDB1 0.236 20360068 Q8IXZ2 Q3U1J4 ZC3H3 DDB1 0.236 26496610 Q86YZ3 Q3U1J4 HRNR DDB1 0.236 26496610 Q92889 Q3U1J4 ERCC4 DDB1 0.236 26496610 Q8WUA4 Q3U1J4 GTF3C2 DDB1 0.236 26496610 Q8TEL6 Q3U1J4 TRPC4AP DDB1 0.236 20360068 Q8WUH6 Q3U1J4 TMEM263 DDB1 0.236 26496610 Q8WV16 Q3U1J4 DCAF4 DDB1 0.236 20360068 Q9H9Q2 Q3U1J4 COPS7B DDB1 0.236 20360068 Q99633 Q3U1J4 PRPF18 DDB1 0.236 26496610 Q9H496 Q3U1J4 TOR1AIP2 DDB1 0.236 26496610 Q9Y266 Q3U1J4 NUDC DDB1 0.236 20360068 Q9HD33 Q3U1J4 MRPL47 DDB1 0.236 26496610 Q9P206 Q3U1J4 KIAA1522 DDB1 0.236 26496610 Q9UBW8 Q3U1J4 COPS7A DDB1 0.236 20360068 Q8BP00 Q3U1J4 IQCB1 DDB1 0.236 21565611 Q3U1J4 P00519 DDB1 ABL1 0.623 12107171 Q7L5N1 Q3U1J4 COPS6 DDB1 0.332 20360068,26496610 Q9NZJ0 Q3U1J4 DTL DDB1 0.332 20360068,26496610 Q5QP82 Q3U1J4 DCAF10 DDB1 0.416 26496610,20360068 Q3U1J4 Q13098 DDB1 GPS1 0.416 26496610,20360068 Q3U1J4 Q13619 DDB1 CUL4A 0.416 26496610,20360068 Q3U1J4 Q13620 DDB1 CUL4B 0.416 26496610,20360068 Q58WW2 Q3U1J4 DCAF6 DDB1 0.416 26496610,20360068 Q5T6F0 Q3U1J4 DCAF12 DDB1 0.416 26496610,20360068 Q8TEB1 Q3U1J4 DCAF11 DDB1 0.416 26496610,20360068 Q92466 Q3U1J4 DDB2 DDB1 0.416 26496610,20360068 Q9BT78 Q3U1J4 COPS4 DDB1 0.416 26496610,20360068 Q9Y4B6 Q3U1J4 VPRBP DDB1 0.416 26496610,20360068 Q9BW61 Q3U1J4 DDA1 DDB1 0.416 26496610,20360068 Q9C0C7 Q3U1J4 AMBRA1 DDB1 0.416 26496610,20360068 Q9NXF7 Q3U1J4 DCAF16 DDB1 0.416 26496610,20360068 Q9UNS2 Q3U1J4 COPS3 DDB1 0.416 26496610,20360068 Q921E6 Q3U1J4 EED DDB1 0.126 24457600 Q9CQ60 Q3U1J4 PGLS DDB1 0.081 16615898 Q3U1J4 Q15637 DDB1 SF1 0.126 26420826 Q3U1J4 B4DDV3 DDB1 B4DDV3 0.126 26496610 Q3U1J4 E7EM64 DDB1 COPS6 {ECO:0000313|ENSEMBL:ENSP00000400617} 0.126 26496610 Q3U1J4 F5GZ90 DDB1 DTL {ECO:0000313|ENSEMBL:ENSP00000443870} 0.126 26496610 Q3U1J4 P02340 DDB1 TP53 0.21 17967871 Q8N6T7 Q3U1J4 SIRT6 DDB1 0.126 26496610 Q8NFQ8 Q3U1J4 TOR1AIP2 DDB1 0.126 26496610 Q99J79 Q3U1J4 DDB2 DDB1 0.21 12107171 Q3U1J4 P52927 DDB1 HMGA2 0.126 26045162