PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Huwe1 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ipo11 i2d exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat3 Huwe1 15102471 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eed 24457600 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ndn Huwe1 22442722 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn2a Huwe1 22754359 biogrid exp, ortho Mcl1 Huwe1 21613222 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Huwe1 16615898 intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myc Huwe1 22754359 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G Ubc Huwe1 23649778 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Unk 25737280 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Huwe1 22754359 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eif1ax ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Nek9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psme3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ldha Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ube2v2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tuba1c Huwe1 ortho P Eif2s1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Oat Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ipo5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Paics ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psma5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mccc2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ahsa1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnaja1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Uchl5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 P33monox ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ndufa13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ppp1r10 ortho P Psmd3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eef1e1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Sf3a1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhah Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nos2 Huwe1 ortho G Eef1d Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcna Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hnrnpk Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncam1 Huwe1 ortho G G G G G G G G G G G G G G G G G Huwe1 Tut1 ortho G G G G G G G G G G G G G Eef1b Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl18 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Parp1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Phax ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eftud2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Pygl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Pdhb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Babam1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsp90b1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mkl2 Huwe1 ortho P Hnrnpa2b1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Asna1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xrcc5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Cct8 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Mccc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Htt Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim28 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Uso1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dld Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Atp5c1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Med20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ak2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Npm1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rpl15 ortho P Huwe1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Dnajb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myod1 Huwe1 ortho G G Ywhag Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccl1 Huwe1 ortho Rbbp7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rfc5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ddx1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Wdr82 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eif3f ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Huwe1 ortho G G G G G G G G G G G G G Huwe1 Wipi2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Adrm1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Srsf2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atm Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2e3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prdx4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ruvbl2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ola1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Prpf19 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ssr4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gigyf2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcnp Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc6 Huwe1 ortho G G G G G G G G Ppia Huwe1 ortho P Rangap1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psma1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Srp14 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Papola Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mcm2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddb1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dpm1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tiprl ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tbl1x ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Acly ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tfcp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fam91a1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dvl3 Huwe1 ortho Huwe1 Pias2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Clk2 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pkm Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Mutyh ortho G G G Huwe1 Mfn2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Idh3a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ezh2 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G Csnk2a2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wdr91 Huwe1 ortho P Huwe1 Ilf3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Cd2ap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Zbtb33 ortho Ckb Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psma6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsd17b10 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mras Huwe1 ortho G G G G G G G G G G G G G Rps9 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Bub3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcbp2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Phb2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncbp1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Cdc20 ortho G G G G G G G G G G G G G G G G G G G G G G Maml1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp5a1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Calr Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep250 Huwe1 ortho Huwe1 Rnf11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Shoc2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Huwe1 ortho Huwe1 Epb41l3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Nasp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Abl1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnl1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cltc Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Anxa5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rassf4 ortho Psmd14 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Pccb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eprs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Csde1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctsd Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Get4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ddx21 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ncln ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps14 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eif4a3 ortho P Huwe1 Flna ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ubxn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smad2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tars ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smek1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps8 Huwe1 ortho P Mcm4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctnnb1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pc Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tufm ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xpo1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psma4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rabep2 ortho P G G G G G G G G G G G Hsph1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Erp29 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fap Huwe1 ortho G G G G G G G G G G G G G G G Huwe1 Dlg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspd1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rtn4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Unc45a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snrpa1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rfxank ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Srsf1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ldhb Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Esr1 Huwe1 ortho G G G G G Vcp Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eif3m ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl12 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdap1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2g1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aldh3a2 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Bloc1s5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Hnrnpu ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crkl Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psmd11 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mre11a Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Gnb2l1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Capza1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Capzb Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Slc25a19 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rad51d Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ogt ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sap30bp Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Sfpq ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vamp3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rps19 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcbp1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpnb1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl5 Huwe1 ortho P Huwe1 Pgam5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tubb2a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crk Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fam119b Huwe1 ortho Hspa4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccdc8 Huwe1 ortho Arf1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mthfd2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Med4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psma7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psma2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc6 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Gtf2a1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps15a Huwe1 ortho P Rpl13a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Spag9 Huwe1 ortho P Ssb Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psmd8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Hadhb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Limch1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Nudt21 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Sf3b3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Capns1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Pdia6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps16 Huwe1 ortho P UPF0472 protein C16orf72 homolog Huwe1 ortho Prdx6 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl8 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tns2 ortho G G G G G G G G G G G G G G G G G G G G G Pdha1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Myl6b ortho P G G G G Atp5b Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G Tubb4b Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac2 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Map1lc3b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nuclear receptor coactivator 4, Protein Ncoa4 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl23 Huwe1 ortho P Cct2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Actr1a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mars Huwe1 ortho P Huwe1 Psmd6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Cdk5rap3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Sfxn3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Copb2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Atg3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ganab ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Slc25a3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp49 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Agr2 Huwe1 ortho GP G G G G G G G G Huwe1 Lsm12 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Uqcrc2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ell Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dvl1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Raf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Prpf8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptch1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnajc8 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsp90aa1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps13 Huwe1 ortho P G G G G G G G G G G G G Huwe1 Vcpip1 ortho Eef2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sub1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Cse1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ankra2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Lsm4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Wwox ortho G G G G G G G G G G G G G G G G G G G G Eif5a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ap3s2 ortho GP G G G G G G G Huwe1 Ddit4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psmd13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspb1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Sirt7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aldoa Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Uba1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Larp7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Canx Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ca2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dbt Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Acacb Huwe1 ortho GP G G G G G G G G G G G G G G G Tubb5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gpi Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Srsf3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Lsm14b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tcp1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psmd12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpa2 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Egfr Huwe1 ortho GP G G G G G G G G G G G G G G G G G Mcm6 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Pcca ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nap1l1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpp30 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxb1 Huwe1 ortho Snrpb Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Tox4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ddhd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp50 Huwe1 ortho P Rps10 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fasn Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rprd1b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G MCG140784, Protein Try10, Trypsin 10, Trypsinogen 10 Huwe1 ortho P Huwe1 Serine hydroxymethyltransferase ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ruvbl1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Myh9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rpl4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ino80 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Prmt1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nr1d1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rb1cc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif4a1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Psmd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Copg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Khsrp Huwe1 ortho P Huwe1 Nono ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G C1qbp Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ilf2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Kctd2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps17 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Phb Huwe1 ortho P Huwe1 Luc7l2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Kdm4a ortho Pgk1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Set ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Utp23 ortho Gdi2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Kifc1 ortho P G G G G G G G G G G G G G Huwe1 Dnaja2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Faf2 Huwe1 ortho P Huwe1 Cul3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Laptm5 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps25 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Sf3a3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp9x Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Hdac11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Psme1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Furin Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Slc25a5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Atp1a1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Stk4 ortho P G G G G G G G Cdc5l Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Cs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fyn Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ufd1l Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl10a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G U2af2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rbm10 ortho Ddost Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hsp90ab1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Naca Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Fbxo6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Usp15 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Nucks1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Txndc9 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fam175b Huwe1 ortho P Psmb7 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx46 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Snrpd3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps24 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpna2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp1ca Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl3 Huwe1 ortho P Rpl7a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brcc3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl27a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncl Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nudc Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Serbp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nckap1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sprtn Huwe1 ortho Tead2 Huwe1 ortho G G G G G Psma3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps18 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3e Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Rassf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 UPF0568 protein C14orf166 homolog ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Shfm1 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbxw11 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Hist3h2bb ortho Rpl22 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Prkar1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Actn4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Zbtb17 Huwe1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cpt1a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stmn1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct3 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tfrc Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhaz Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmc2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahcy Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Protein Njmu-R1 ortho P Rps23 Huwe1 ortho P Rplp0 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl27 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kif5b Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Cdyl2 ortho Lrrc16a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Rad23a Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Mok ortho G G G G G G G G G G G G G G G G Hspa5 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h2ab, Hist1h2ac, Hist1h2ad, Hist1h2ae, Hist1h2ag, Hist1h2ai, Hist1h2an, Hist1h2ao Huwe1 ortho P Huwe1 Ssr1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Smad9 ortho Ube2l3 Huwe1 ortho P Mdh2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct4 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vamp2 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ech1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Strap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ndufs3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Polb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Dnaja3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hnrnph1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Phgdh Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Snd1 Huwe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snrnp200 Huwe1 ortho P Huwe1 Eif4e2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ppih ortho P

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q7TMY8 cosedimentation 16615898 colocalization C 1216 Q7TMY8 P42227 two hybrid 15102471 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Stat3 Huwe1 MI:0027(cosedimentation)|MI:0027(cosedimentation)|MI:0018(two hybrid)|MI:0027(cosedimentation) 15102471,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(intact)|(intact) UniProt_167131|UniProt_167130|UniProt_162529|UniProt_167134 neutral component|neutral component|bait|neutral component neutral component|neutral component|prey|neutral component Tp53 Huwe1 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22213803,22754359 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0796(suppressive genetic interaction defined by inequality) (biogrid)|(biogrid) BIOGRID_321997|BIOGRID_323523 prey|bait bait|prey Myc Huwe1 MI:0004(affinity chromatography technology) 22754359 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321998 prey bait Mcl1 Huwe1 MI:0004(affinity chromatography technology) 21613222 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_316064 prey bait Huwe1 Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332362 prey bait Cdkn2a Huwe1 MI:0004(affinity chromatography technology) 22754359 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321996 prey bait Ndn Huwe1 MI:0004(affinity chromatography technology) 22442722 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_323067 bait prey

PPI - HINT Gene A Gene B PMID Method Quality NDN HUWE1 22442722 0018 LC STAT3 HUWE1 15102471 0018 LC YWHAE HUWE1 16615898 0027 LC HUWE1 PGLS 16615898 0027 LC MYC HUWE1 22754359 0004 LC TP53 HUWE1 22754359 0004 LC UBC HUWE1 23649778 0004 LC MCL1 HUWE1 21613222 0004 LC CDKN2A HUWE1 22754359 0004 LC HUWE1 EED 24457600 0004 LC HUWE1 CHAF1A 26365490 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q7TMY8 P62259 HUWE1 YWHAE 0.081 16615898 Q7TMY8 P25233 HUWE1 NDN 0.183 22442722 Q7TMY8 P0CG50 HUWE1 UBC 0.126 23649778 Q7TMY8 P01108 HUWE1 MYC 0.21 22754359 Q7TMY8 P02340 HUWE1 TP53 0.21 22754359 Q7TMY8 P42227 HUWE1 STAT3 0.183 15102471 Q7TMY8 P51480 HUWE1 CDKN2A 0.21 22754359 Q7TMY8 P97287 HUWE1 MCL1 0.21 21613222 Q7TMY8 Q64364 HUWE1 CDKN2A 0.21 22754359 Q8BL48 Q7TMY8 UNK HUWE1 0.126 25737280 Q921E6 Q7TMY8 EED HUWE1 0.126 24457600 Q9CQ60 Q7TMY8 PGLS HUWE1 0.081 16615898 Q9QWF0 Q7TMY8 CHAF1A HUWE1 0.126 26365490 Q7TMY8 P45844 HUWE1 ABCG1 0.21 26296893