PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Vhl Sumo1 17981124 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Nr2c1 17187077 dip exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ranbp2 15094046 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Maf Sumo1 19553542 innatedb exp G Sumo1 Rbbp7 19189660 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ikzf1 15767674 intact exp P G G G G G Sumo1 Mthfs 22303332 biogrid exp P Anxa2 Sumo1 25775977 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Junb Sumo1 i2d exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sept2 Sumo1 20372094 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Irf7 18635538 innatedb exp GP G G G G G G G G G G G G G G G G G G G G G G G G Irf8 Sumo1 18955028 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G Slc1a2 Sumo1 17823119 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G Pex2 Sumo1 11591653 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Irf3 18635538 innatedb exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Sumo1 i2d exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pias3 Sumo1 12387893 innatedb,biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Sumo1 17086174,15094046 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mdm2 Sumo1 19090619,17086174,15897463,21183956 biogrid,dip exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Smad4 22366399 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Srebf1 24379443 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ikzf3 Sumo1 15767674 intact exp, ortho Daxx Sumo1 21383010 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ube2i 20077568 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Pml 15094046 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G Sp3 Sumo1 21085687 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Klf5 18782761 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Hif1a 15225651,17981124 biogrid,mint,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Npm1 15897463 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Irf1 Sumo1 18955028,12387893 innatedb,biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pax6 Sumo1 21084637 dip exp, ortho G G G G G Sumo1 Casp8ap2 11591653 i2d,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myb Sumo1 16162816 biogrid exp, ortho G G G G G G G G G G G G G G G Rangap1 Sumo1 15094046,19033381 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Uimc1 17698038 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Gmcl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Tp73 ortho G Sumo1 Sumo3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Kcnip3 ortho G G G G G G G Sumo1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Blm Sumo1 ortho G G G G G G Sumo1 Nr3c2 ortho Sumo1 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Setx Sumo1 ortho Slc2a1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Crebbp Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Edaradd ortho G G G G G Sumo1 Kpnb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Sox10 ortho G G G G G G G G G G G G G G Sumo1 Bub1b ortho G G G G G G G G G G G G Sumo1 Cdc5l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Zcchc12 ortho Sumo1 Ccdc67 ortho Protein Nup153 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Wdr33 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Tdp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Dtx2 ortho G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ncoa2 ortho G G G G G Sumo1 Vcp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 MCG3834, Protein Zbtb16, Zinc finger and BTB domain containing 16 ortho G G G G G G G G G G G G G G G G G G Msx1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G Sumo1 Hnrnpc ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Hdac4 ortho Sumo1 Fam120c ortho P Sumo1 Protein Zbtb26, Zinc finger and BTB domain containing 26, Zinc finger and BTB domain containing 26, isoform CRA_b ortho Ptpn1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rad52 Sumo1 ortho G G G G G G G G G G G G G G G G G G Sumo1 Sptbn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tnfrsf1a Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Actn3 Sumo1 ortho GP G G G G G G G G G G G Sumo1 Chd8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Faslg Sumo1 ortho G Sumo1 Ppil3 ortho P Sumo1 Sart1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Chaf1a ortho Sumo1 Srebf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Pias2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif4e Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Arpc1b ortho P Sssca1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Iap Sumo1 ortho G G Sumo1 Phc1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Zmym2 ortho P Sumo1 Nf1 ortho GP G G G G G G G G G G G G G G G G G G G G Sumo1 Zmynd11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rad51 ortho G G G G G G G G G G G G G Sumo1 Bcl11a ortho G G G G G G G G G G G G G G G G G G G G Sumo1 Topors ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnmt3b Sumo1 ortho G G G G G G G G G G G Sumo1 Cenpv ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Mul1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Zbtb6 ortho Brca1 Sumo1 ortho G G G G G G G G G G G G G Sumo1 Sae1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Mkl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp25 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Atxn3 ortho P Elk1 Sumo1 ortho G G G G G Sumo1 Ppm1j ortho Sumo1 Rnf111 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Uncharacterized protein C11orf65 homolog ortho Sumo1 Uspl1 ortho Sumo1 Kcnb1 ortho G G G G G G G G G G G G G Sumo1 Nin ortho G G G G G G G G G G G G G G G G G G G G G Sumo1 Ikbke ortho G G G G G G G G G G G G G Kcnk1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Arid3a ortho G G G G G G G G G G G G G G G G G G G G G G G G G Protein Zfp462 Sumo1 ortho Sumo1 Tfcp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ino80b ortho G G G G G Prox1 Sumo1 ortho G G G G Sumo1 Sall1 ortho G G Sumo1 Kcna5 ortho G G G G G G G G G G G G Egr1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ssb Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Sin3a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ppp1r10 ortho P Bckdk Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sox2 Sumo1 ortho G G G G G G G G G G G Sumo1 Ogt ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cebpa Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G 4732471D19Rik Sumo1 ortho G G G G G G G G G G G G G G G G Ar Sumo1 ortho G G G G G G G G G G G G G G G G Sumo1 Sept6 ortho P G G G G G G G G G G G G G G G G G Sumo1 Tsc22d3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pias1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Cdc40 ortho P Cebpb Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pfdn2 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Casp2 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ncor2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nr3c1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Satb1 ortho G G G G G G G G G G G G G G G G G G G G G G G Tp63 Sumo1 ortho G G G G G G G Sumo1 Dhx30 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rnf4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Pdgfc ortho G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rad54b ortho Sumo2 Sumo1 ortho P Sumo1 Tank ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Aldh18a1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Adarb2 ortho Sumo1 Arpc2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Zfp362, Zinc finger protein 362 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atf2 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Cdk9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Nr1h4 ortho G G G G G G G G Polr2g Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Top2b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rbak ortho Yap1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Znf687 ortho Sumo1 Trim28 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf169 Sumo1 ortho Sumo1 Mef2a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Tollip ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Bend3 ortho Sumo1 Psmd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Creb1 ortho GP G G G G G G G G G G G G G G G G G G G G G Atxn1 Sumo1 ortho Sumo1 Tcf4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rnf167 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Irak1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Htt Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rara Sumo1 ortho G G Sumo1 Ncoa1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Fan1 ortho Parp1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Hipk3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Chd2 Sumo1 ortho P Sumo1 Znf768 ortho G G G G G G G G G G G G G G G G G G G Cnr1 Sumo1 ortho G G G G G Rps3 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Top1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Glp1r Sumo1 ortho G G Cbx4 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Mbd1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Birc3 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Uba2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Zcchc7 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Nup107 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Protein Chd3 Sumo1 ortho P Hsf1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2k Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Hipk2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Prkacb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rwdd3 ortho G G G Sumo1 Zmym5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Pias4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Capn2 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sox6 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Pkm Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Card9 Sumo1 ortho Sumo1 Prdm1 ortho G G G G G G G G G G G G G G G G Sumo1 Protein Zfp317, Zinc finger protein 75, isoform CRA_a ortho Fas Sumo1 ortho G G G G G G G G G G G G G G G G G Pabpc1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rsbn1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Kat5 ortho Sumo1 Znf592 ortho P Fbf1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Traf6 ortho G G G G G G G G G G G G G G G G G G G G Sumo1 Sept3 ortho P G G G G G G G G G G G G G G G G Sumo1 Rad54l2 ortho G G G G G G G G G G G G G G Sumo1 Etv6 ortho P G G G G G G G G G G G G G G G G Sumo1 Seh1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Protein Zfp174, Zinc finger protein 174 Sumo1 ortho Arpc4 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Psip1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Cul7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnm1 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G Sumo1 Top2a ortho G G G G G G G G G G G G G G G G G G G G G G Sumo1 Znf451 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Tp53bp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Arid5b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lef1 Sumo1 ortho G G G Sumo1 Ptgs2 ortho G G G G G G G G Grik2 Sumo1 ortho G G G G Sumo1 Hdac9 ortho Ikbkg Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncoa3 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Nfkbia ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Park7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fos Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Casp8 Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Nfe2l2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stom Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Prdx5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Pygm ortho GP G G G G G G G G G G G G G G G G G G G Sumo1 Traf4 ortho G G G G G G G G G G G G G G G G G G Ugdh Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Toe1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Idh3a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Atxn7 ortho G G G G G G G G G G G G Dvl1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Senp1 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Ing2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Nfkb2 ortho P G G G G G G G G G G G G G Sumo1 Fsbp ortho Znf106 Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Rreb1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Dynll2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Mtor ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Hgs ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Epas1 ortho G G G G G G G G G G G G G G G G G G G G G Sumo1 Zhx1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Senp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Parp12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxm1 Sumo1 ortho G G G G G G G G Sumo1 Senp6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Dyrk2 ortho Sumo1 Mitf ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Park2 ortho G G G G Wrn Sumo1 ortho G G G G G G G G G G G G G G G G G G G G G G G Hnrnpk Sumo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Trps1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Fam118b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Uncharacterized protein C18orf25 homolog ortho Sumo1 Zmym3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Tbk1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sumo1 Mapk1ip1l ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P63166 - 10788439 - C 3 P63166 - 10788439 - C 3 Q06609 P63166 - 10666456 - X 2 Q06609 P63166 - 10666456 - X 2 P63166 - 11591653 - X 2 P63280 P63166 - 10666456 - X 2 P43351 P63166 - 10666456 - X 2 P63166 P05627 - 10788439 - X 2 P09450 P63166 - 10788439 - X 2 Q3UKR0 P63166 x-ray crystallography 21383010 association X 2 Q3UKR0 P63166 pull down 21383010 direct interaction X 2 Q60973 P63166 affinity chromatography technology 19189660 physical association X 2 P63280 P63166 enzymatic study 15094046 direct interaction X 2 P63166 O15169-2 affinity chromatography technology 12223491 physical association X 2 P63166 P48432 pull down 17097055 direct interaction X 2 P63166 D3Z3A6 enzymatic study 15094046 direct interaction X 2 P63166 D3Z3A6 affinity chromatography technology 24911587 physical association X 2 P63166 Q3UV15 affinity chromatography technology 18617892 physical association X 2 P63166 Q3UUX5 affinity chromatography technology 16162816 physical association X 2 Q6PF93 P63166 affinity chromatography technology 23569248 physical association X 2 Q3U5M1 P63166 affinity chromatography technology 12387893 physical association X 2 Q3U5M1 P63166 two hybrid 18955028 direct interaction X 2 Q3U5M1 P63166 pull down 18955028 direct interaction X 2 Q3U5M1 P63166 affinity chromatography technology 18955028 physical association X 2 O70494 P63166 affinity chromatography technology 21085687 physical association X 2 P63166 affinity chromatography technology 17698038 physical association X 2 O09130 P63166 x-ray crystallography 20077568 association X 2 Q9D110 P63166 enzymatic study 22303332 direct interaction X 2 Q9D110 P63166 affinity chromatography technology 22303332 physical association X 2 Q3UQU1 P63166 pull down 23673342 direct interaction X 2 P63166 affinity chromatography technology 17525163 physical association X 2 P23611 P63166 two hybrid 18955028 direct interaction X 2 P63166 D6W5D9 affinity chromatography technology 18681895 physical association X 2 P63166 affinity chromatography technology 15897463 physical association X 2 P63166 Q8C3V4 affinity chromatography technology 24911587 physical association X 2 P63166 affinity chromatography technology 19995909 physical association X 2 P63166 P42208 affinity chromatography technology 20372094 physical association X 2 Q549C9 P63166 enzymatic study 15094046 direct interaction X 2 Q549C9 P63166 affinity chromatography technology 17086174 physical association X 2 P97471 P63166 affinity chromatography technology 22366399 physical association X 2 P63015-3 P63166 affinity chromatography technology 21084637 physical association X 2 P63015-3 P63166 affinity chromatography technology 21084637 physical association X 2 Q9ERU9 P63166 enzymatic study 15094046 direct interaction X 2 P46061 P63166 enzymatic study 15094046 direct interaction X 2 P46061 P63166 affinity chromatography technology 8978815 physical association X 2 P46061 P63166 affinity chromatography technology 19033381 physical association X 2 Q3UHJ1 P63166 affinity chromatography technology 24260396 physical association X 2 P63166 affinity chromatography technology 17823119 physical association X 2 P63166 affinity chromatography technology 17823119 physical association X 2 O08586 P63166 affinity chromatography technology 22713753 physical association X 2 Q61221 P63166 affinity chromatography technology 17981124 physical association X 2 P23804 P63166 affinity chromatography technology 15897463 physical association X 2 P23804 P63166 affinity chromatography technology 17086174 physical association X 2 P23804 P63166 affinity chromatography technology 21183956 physical association X 2 P09450 P63166 coimmunoprecipitation 10788439 association X 2 Q505F1 P63166 anti bait coimmunoprecipitation 17187077 covalent binding X 2 Q505F1 P63166 anti bait coimmunoprecipitation 18682553 covalent binding X 2 Q505F1 P63166 interaction detection method 17187077 covalent binding X 2 Q505F1 P63166 anti bait coimmunoprecipitation 18682553 covalent binding X 2 Q505F1 P63166 anti bait coimmunoprecipitation 17187077 covalent binding X 2 P63015-2 P63166 anti bait coimmunoprecipitation 21084637 physical association X 2 P63015-2 P63166 anti bait coimmunoprecipitation 21084637 physical association X 2 P23804 P63166 anti bait coimmunoprecipitation 19090619 physical association X 2 P26367 P63166 anti bait coimmunoprecipitation 21084637 physical association X 2 P26367 P63166 anti bait coimmunoprecipitation 21084637 physical association X 2 A0A024R4C3 P63166 two hybrid 10961991 physical association X 2 P21605 P63166 two hybrid 11129635 physical association X 2 O08900 P63166 two hybrid 15767674 physical association X 2 P63166 A8K3M3 anti tag coimmunoprecipitation 17159996 physical association X 2 P63166 A8K3M3 anti tag coimmunoprecipitation 17159996 physical association X 2 P55098 P63166 two hybrid array 11591653 physical association X 2 Q9WUF3 P63166 two hybrid array 11591653 physical association X 2 Q03267 P63166 two hybrid 15767674 physical association X 2 Q03267 P63166 anti bait coimmunoprecipitation 15767674 physical association X 2 Q61221 P63166 anti bait coimmunoprecipitation 15225651 physical association X 2 Q61221 P63166 imaging technique 15225651 colocalization X 2 Q61221 P63166 anti bait coimmunoprecipitation 15225651 physical association X 2 Q61221 P63166 anti bait coimmunoprecipitation 15225651 physical association X 2 Q61221 P63166 anti bait coimmunoprecipitation 15225651 physical association X 2 Q61221 P63166 imaging technique 15225651 colocalization X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Sumo1 Mthfs MI:0415(enzymatic study)|MI:0415(enzymatic study) 22303332 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_324494|BIOGRID_324495 bait|prey prey|bait Sumo1 Ikzf1 MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 15767674 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(intact)|(intact) UniProt_80038|UniProt_163988|UniProt_163994 prey|prey|prey bait|bait|bait Sumo1 Pik3c3 MI:0004(affinity chromatography technology) 23569248 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_331175 prey bait Pex2 Sumo1 MI:0397(two hybrid array) 11591653 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_161213 bait prey Sox2 Sumo1 MI:0415(enzymatic study) 17097055 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_324053 bait prey Sumo1 Nr2c1 MI:0006(anti bait coimmunoprecipitation) 18682553 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0195(covalent binding) MI:0465(dip) DIP_353 - - Sumo1 Casp8ap2 MI:0096(pull down)|MI:0397(two hybrid array) 11591653,23673342 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(intact) BIOGRID_331754|UniProt_161265 prey|prey bait|bait Sumo1 Ranbp2 MI:0415(enzymatic study) 15094046 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_325354 bait prey Sumo1 Nfkb2 MI:0004(affinity chromatography technology) 18617892 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_312270 prey bait Sumo1 Irf8 MI:0018(two hybrid) 18955028 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_322307 prey bait Sumo1 Smad4 MI:0004(affinity chromatography technology) 22366399 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321590 prey bait Rangap1 Sumo1 MI:0415(enzymatic study)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15094046,19033381,8978815 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_325353|BIOGRID_325643|BIOGRID_325672 prey|bait|bait bait|prey|prey Irf1 Sumo1 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 12387893,18955028 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid)|(biogrid) BIOGRID_321606|BIOGRID_322309|BIOGRID_322306|BIOGRID_322311 bait|prey|bait|prey prey|bait|prey|bait Slc1a2 Sumo1 MI:0018(two hybrid)|MI:0112(ubiquitin reconstruction)|MI:0112(ubiquitin reconstruction)|MI:0018(two hybrid)|MI:0112(ubiquitin reconstruction) 16093310,17823119 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(intact)|MI:0465(dip)|(biogrid)|MI:0471(mint) BIOGRID_322313|UniProt_196162|DIP_44448|BIOGRID_322314|MINT_121308 prey|-|-|bait|- bait|-|-|prey|- Myb Sumo1 MI:0096(pull down) 16162816 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_319855 prey bait Ikzf3 Sumo1 MI:0006(anti bait coimmunoprecipitation) 15767674 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_163989 bait prey Sp3 Sumo1 MI:0004(affinity chromatography technology) 21085687 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_319521 bait prey Nfatc2ip Sumo1 MI:0096(pull down) 20077568 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association) (biogrid) BIOGRID_322020 bait prey Pax6 Sumo1 MI:0096(pull down)|MI:0096(pull down) 21084637 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_319534|BIOGRID_319533 prey|bait bait|prey Sumo1 Uimc1 MI:0018(two hybrid) 17698038 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322142 bait prey Tp53 Sumo1 MI:0004(affinity chromatography technology)|MI:0415(enzymatic study) 15094046,17086174 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction) (biogrid)|(biogrid) BIOGRID_316213|BIOGRID_325356 bait|prey prey|bait Sumo1 Hif1a MI:0004(affinity chromatography technology)|MI:0428(imaging technique)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0428(imaging technique)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation)|MI:0428(imaging technique)|MI:0428(imaging technique)|MI:0006(anti bait coimmunoprecipitation)|MI:0006(anti bait coimmunoprecipitation) 15225651,17981124 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association)|MI:0403(colocalization)|MI:0403(colocalization)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|(intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact)|(intact) BIOGRID_312353|MINT_58846|UniProt_165303|UniProt_165298|MINT_58847|UniProt_165302|UniProt_165299|MINT_58844|MINT_58845|UniProt_165301|UniProt_165300 prey|bait|neutral component|prey|bait|neutral component|bait|unspecified role|unspecified role|bait|prey bait|prey|neutral component|bait|prey|neutral component|prey|unspecified role|unspecified role|prey|bait Sumo1 Ube2i MI:0415(enzymatic study) 15094046 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_325352 bait prey Mdm2 Sumo1 MI:0006(anti bait coimmunoprecipitation)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 15897463,17086174,19090619,21183956 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|(biogrid)|(biogrid)|(biogrid) DIP_711|BIOGRID_319560|BIOGRID_328481|BIOGRID_316211 -|bait|prey|bait -|prey|bait|prey Sept2 Sumo1 MI:0004(affinity chromatography technology) 20372094 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_319573 bait prey Pou5f1 Sumo1 MI:0004(affinity chromatography technology) 17525163 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_312458 prey bait Daxx Sumo1 MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography) 21383010 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0914(association) (biogrid)|(biogrid) BIOGRID_319594|BIOGRID_319592 bait|bait prey|prey Sumo1 Pml MI:0415(enzymatic study) 15094046 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_325355 bait prey Sumo1 Rbbp7 MI:0004(affinity chromatography technology) 19189660 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_322250 prey bait Sumo1 Traf3 MI:0018(two hybrid) 24260396 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_331673 prey bait Sumo1 Npm1 MI:0004(affinity chromatography technology) 15897463 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_328482 bait prey

PPI - HINT Gene A Gene B PMID Method Quality IKZF3 SUMO1 15767674 0018 LC DAXX SUMO1 21383010,21383010 0114,0096 LC PIAS3 SUMO1 12387893 0018 LC JUN SUMO1 10788439,10788439 0045,0004 LC JUNB SUMO1 10788439,10788439 0019,0004 LC IRF1 SUMO1 18955028,18955028,18955028 0096,0018,0004 LC IRF8 SUMO1 18955028 0018 LC PEX2 SUMO1 11591653 0397 HT SUMO1 IKZF1 15767674,15767674 0006,0018 LC SUMO1 CASP8AP2 11591653 0397 HT DAXX SUMO1 21383010,21383010 0114,0096 LC SP3 SUMO1 21085687 0004 LC TP53 SUMO1 17086174,15094046 0004,0004 LC JUN SUMO1 10788439,10788439 0045,0004 LC MYB SUMO1 16162816 0004 LC ANXA2 SUMO1 25775977 0007 LC JUNB SUMO1 10788439,10788439 0019,0004 LC IRF1 SUMO1 18955028,18955028,12387893,18955028 0096,0018,0004,0004 LC POU5F1 SUMO1 17525163 0004 LC MDM2 SUMO1 21183956,15897463,17086174,19090619 0004,0004,0004,0006 LC VHL SUMO1 17981124,17981124 0096,0004 LC SEPT2 SUMO1 20372094 0004 LC SLC1A2 SUMO1 17823119 0004 LC RANGAP1 SUMO1 19033381,15094046 0004,0004 LC MAF SUMO1 19553542 0007 LC PAX6 SUMO1 21084637 0006 LC SUMO1 IRF7 18635538 0007 LC SUMO1 IRF3 18635538 0007 LC SUMO1 SMAD4 22366399 0004 LC SUMO1 IKZF1 15767674,15767674 0006,0018 LC SUMO1 NR2C1 17187077,18682553 0006,0006 LC SUMO1 UIMC1 17698038 0004 LC SUMO1 PML 15094046 0004 LC SUMO1 RBBP7 19189660 0004 LC SUMO1 HIF1A 17981124,15225651,15225651 0004,0006,0428 LC SUMO1 NPM1 15897463 0004 LC SUMO1 SF1 19995909 0004 LC SUMO1 MTHFS 22303332 0004 LC SUMO1 RANBP2 15094046 0004 LC SUMO1 NFKB2 18617892 0004 LC SUMO1 SREBF1 24379443,24379443 0006,0813 LC SUMO1 KLF5 18782761 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q60953 P63166 PML SUMO1 0.21 15094046 P63166 P23611 SUMO1 IRF8 0.309 18955028 Q60973 P63166 RBBP7 SUMO1 0.21 19189660 P63166 O70494 SUMO1 SP3 0.21 21085687 Q9WUF3 P63166 CASP8AP2 SUMO1 0.126 11591653 Q9Z0Z7 P63166 KLF5 SUMO1 0.21 18782761 P63166 P07356 SUMO1 ANXA2 0.21 25775977 P63166 P02340 SUMO1 TP53 0.376 17086174,15094046 Q03267 P63166 IKZF1 SUMO1 0.454 15767674 P63166 P46061 SUMO1 RANGAP1 0.376 19033381,15094046 Q61221 P63166 HIF1A SUMO1 0.569 17981124,15225651 P63166 O35613 SUMO1 DAXX 0.523 21383010 Q9WTN3 P63166 SREBF1 SUMO1 0.376 24379443 Q505F1 P63166 NR2C1 SUMO1 0.396 17187077,18682553 Q9D110 P63166 MTHFS SUMO1 0.21 22303332 Q9ERU9 P63166 RANBP2 SUMO1 0.21 15094046 P97471 P63166 SMAD4 SUMO1 0.21 22366399 P63166 P42208 SUMO1 SEPT2 0.21 20372094 P63166 P06876 SUMO1 MYB 0.21 16162816 P63166 P23804 SUMO1 MDM2 0.61 15897463,19090619,21183956,17086174 P63166 O54714 SUMO1 PIAS3 0.309 12387893 P63166 O08900 SUMO1 IKZF3 0.309 15767674 P63166 O15350 SUMO1 TP73 0.309 10961991 P63166 P21605 SUMO1 P21605 0.309 11129635 P63166 P18031 SUMO1 PTPN1 0.21 17159996 P63166 P43006 SUMO1 SLC1A2 0.376 17823119 P63166 P40338 SUMO1 VHL 0.623 17981124 Q5U5Q9 P63166 UIMC1 SUMO1 0.21 17698038 P63166 P55098 SUMO1 PEX2 0.126 11591653 Q61937 P63166 NPM1 SUMO1 0.21 15897463 P63280 P63166 UBE2I SUMO1 0.309 20077568 P63166 P15314 SUMO1 IRF1 0.623 18955028