PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Ahctf1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hmga2 Ahctf1 26045162 intact exp G G G G Nanog Ahctf1 17093407 biogrid,i2d exp Ahctf1 Foxp3 22922362 biogrid exp Ahctf1 Eed 24457600 innatedb,biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup43 Ahctf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Kpnb1 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Nup133 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Serine hydroxymethyltransferase ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sirt7 Ahctf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Npm1 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Nup37 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G E2f3 Ahctf1 ortho G G G G G Nup188 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Vapb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup107 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Nup155 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup88 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Nup160 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctnnb1 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup93 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nup62 Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Nup35 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Med19 Ahctf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Sec13 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ahctf1 Slamf1 ortho G G G G G G Islr Ahctf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Faf2 Ahctf1 ortho P Lmna Ahctf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mov10 Ahctf1 ortho G G G G G G G G G G G G G G G G G G G G Ahctf1 Nup85 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G MCG21756, isoform CRA_b, Nup205 protein, Protein Nup205 Ahctf1 ortho P Ahctf1 Seh1l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Nup98 Ahctf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q921E6 Q8CJF7 affinity chromatography technology 24457600 physical association X 2 Q8CJF7 A2RS90 affinity chromatography technology 17093407 physical association X 2 Q53Z59 Q8CJF7 affinity chromatography technology 22922362 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ahctf1 Foxp3 MI:0004(affinity chromatography technology) 22922362 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324600 prey bait Ahctf1 Eed MI:0027(cosedimentation)|MI:0004(affinity chromatography technology) 16615898,24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0403(colocalization)|MI:0915(physical association) (intact)|(biogrid) UniProt_167137|BIOGRID_331993 neutral component|prey neutral component|bait Nanog Ahctf1 MI:0004(affinity chromatography technology) 17093407 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_314219 bait prey

PPI - HINT Gene A Gene B PMID Method Quality YWHAE AHCTF1 16615898 0027 LC HMGA2 AHCTF1 26045162 0096 LC NANOG AHCTF1 17093407 0004 LC AHCTF1 EED 24457600 0004 LC AHCTF1 FOXP3 22922362 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8CJF7 P62259 AHCTF1 YWHAE 0.081 16615898 Q8CJF7 Q80Z64 AHCTF1 NANOG 0.126 17093407 Q921E6 Q8CJF7 EED AHCTF1 0.126 24457600 Q99JB6 Q8CJF7 FOXP3 AHCTF1 0.126 22922362 Q8CJF7 P52927 AHCTF1 HMGA2 0.126 26045162