PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Gnb4 Ywhae 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Grin2b 16635246 intact exp G G G G Gnb4 Dlg4 19455133 intact exp P G G G G G G G G G G Gnb4 Gng4 8636150 dip exp, ortho G G G G G G G Gnb4 Gng13 ortho G G G G G G G Gnb4 Rd3 ortho G Gnb4 Gngt1 ortho G Gnb4 Gng7 ortho Gnb4 Gngt2 ortho P Gnb4 Hspa8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Hoxb5 Gnb4 ortho G G G G G G G Gnaq Gnb4 ortho GP G G G G G G G G G G G G G Gnb4 Fbxo6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tmem185a Gnb4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Pdcl ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Pan2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnai1 Gnb4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Cdk18 ortho G G G G G G G G G G G G G G G Gnb4 Ccnl2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Adrb2 Gnb4 ortho G G G G G G G G G Gnb4 Gng8 ortho Gnb4 Hsf1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 ortho P G G G G Gnb4 Lrriq3 ortho Gnb4 Erbb2 ortho P G G G G G G G G G G G G Fkbpl Gnb4 ortho G G G G G G G G G G G G G G G G G Gnb4 Gng3 ortho G G G G G G G G G G G G G Gnai2 Gnb4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Abce1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Tspan17 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Rgs6 ortho Ankyrin repeat domain 12, isoform CRA_a, Protein Ankrd12 Gnb4 ortho Gnb4 Nr2e1 ortho Tnf Gnb4 ortho Esr1 Gnb4 ortho G G G G G Gnb4 Meis2 ortho G G G G G G G G G G G G G G G G G G G G G Dffa Gnb4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Gng12 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Ripk3 ortho G G G G G G G G G G G Gnb4 Mtnr1b ortho Gnb4 Gng11 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Gng2 ortho G G G G G G G G G G G G G G Slc30a4 Gnb4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nudc Gnb4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Mbd3l1 ortho Gnb4 Gnas ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Limch1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Gnai3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Pfdn5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gna11 Gnb4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Cep97 ortho Gnb4 Mtnr1a ortho Gnb4 Gng10 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gnb4 Xpo1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Pten Gnb4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Gnb4 Gng4 MI:0018(two hybrid) 8636150 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) MI:0465(dip) DIP_117 - - Gnb4 Gnb4 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 8636150 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) MI:0465(dip)|MI:0465(dip)|MI:0465(dip)|MI:0465(dip) DIP_119|DIP_121|DIP_110|DIP_112 -|-|-|- -|-|-|-

PPI - HINT Gene A Gene B PMID Method Quality GNB4 GNG4 8636150 0018 LC GNB4 YWHAE 16615898 0027 LC GNB4 GRIN2B 16635246 0004 HT GNB4 DLG4 19455133 0007 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID P62259 P29387 YWHAE GNB4 0.081 16615898 P50153 P29387 GNG4 GNB4 0.033 8636150 Q62108 P29387 DLG4 GNB4 0.236 19455133 P30671 P29387 GNG7 GNB4 0.033 8636150 P29387 P26769 GNB4 ADCY2 0.033 7761832 Q01097 P29387 GRIN2B GNB4 0.126 16635246 P63214 P29387 GNG3 GNB4 0.033 8636150 P63211 P29387 GNGT1 GNB4 0.033 8636150 P63212 P29387 GNG2 GNB4 0.033 8636150 P63217 P29387 GNG5 GNB4 0.033 8636150