PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Nfe2 Plrg1 20211142 biogrid exp G G G G Ywhae Plrg1 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Foxp3 22922362 biogrid exp Ywhah Plrg1 21311561 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hmga2 Plrg1 26045162 intact exp G G G G Ddx41 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Dhx8 Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Isy1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snrnp200 Plrg1 ortho P Gabarapl2 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G DEAH (Asp-Glu-Ala-His) box polypeptide 38, Protein Dhx38 Plrg1 ortho P G G G G G G Plrg1 Pfkp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Prpf19 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tada2a Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp5b Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Cwc15 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bmi1 Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Cpvl ortho Pabpc1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G App Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbl Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Tenm2 ortho P G G G G G G Sf3a1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Gabarap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usb1 Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Sf3b1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Xpo1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkce Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Sf3a3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Bcas2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Mrpl40 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mdc1 Plrg1 ortho P Snrpd2 Plrg1 ortho P Csnk2a2 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snrpa1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Ccdc94 ortho Ntrk1 Plrg1 ortho Plrg1 Pdhb ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G U2af2 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Ctnnbl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Cul3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vac14 Plrg1 ortho GP G G G G G G G G G G G G G G G Plrg1 Prpf4 ortho P Prpf3 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pcf11 Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct8 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbm14 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl9 Plrg1 ortho P Kpna1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cwc22 Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Zcrb1 ortho Polyadenylate-binding protein, PABP Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cad Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kpna2 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Prpf8 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eftud2 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dhx15 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Suz12 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Snw1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa5 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Magoh Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Xab2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sf3b3 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Uchl5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa4 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspd1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbm22 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdia5 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Cdc40 ortho P Eif3b Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Upf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ap2m1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Plrg1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Lims1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc5l Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp42 Plrg1 ortho Rbm39 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bach1 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif4a3 Plrg1 ortho P Cct5 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plrg1 Hnrnpm ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp6v1b2 Plrg1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Plrg1 Foxp3 MI:0004(affinity chromatography technology) 22922362 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324829 prey bait Nfe2 Plrg1 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313415 bait prey

PPI - HINT Gene A Gene B PMID Method Quality YWHAE PLRG1 16615898 0027 LC YWHAH PLRG1 21311561 0030 LC NFE2 PLRG1 20211142 0018 HT HMGA2 PLRG1 26045162 0096 LC PLRG1 FOXP3 22922362 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q922V4 P62259 PLRG1 YWHAE 0.081 16615898 Q99JB6 Q922V4 FOXP3 PLRG1 0.126 22922362 Q922V4 P68510 PLRG1 YWHAH 0.126 21311561 Q922V4 Q07279 PLRG1 NFE2 0.183 20211142 Q922V4 P52927 PLRG1 HMGA2 0.126 26045162