PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Rnf20 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tfap2a Rnf20 24374663 biogrid exp G G G G G G Rnf20 Sharpin 21829440 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Pgls 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Srebf1 24425205 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Slx4ip ortho Rnf20 Msl1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myo1e Rnf20 ortho P G G G Rnf20 Hist2h2ac ortho P Rnf20 Msl2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2l3 Rnf20 ortho P Rnf20 Cmtr1 ortho P Psmd14 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Htt Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Ube2a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Kif5b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Rnf20 ortho Pcna Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cops5 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Hist1h2bb ortho P Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 Rnf20 ortho P G G G G G G G G G G G G G G Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Rnf20 ortho P G G G G Oaz1 Rnf20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Unc45a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Llgl2 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G Uba1 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd7 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Dsn1 ortho G G G G G G G G G G G G G G G G G G Rnf20 Med23 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Zdhhc17 ortho Rnf20 Snap29 ortho GP G G G G G G G G G G G G G G G G G G G G G G Rbpj Rnf20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Babam1 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Wac ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Postmeiotic segregation increased 1 (S. cerevisiae), Protein Pms1 ortho P Rnf20 Itsn2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Amotl2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Atm ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pa2g4 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Tsnax ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Chek2 ortho G G G G G G G G G G G G G G G G G G G G Fos Rnf20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Il36a ortho G G G G G G G G Rnf20 Cdc73 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Usp15 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Ciapin1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn1a Rnf20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Supt16h ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Stau1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Urm1 ortho G G G G G G G G G G G G G G G G G G G G G Rnf20 Rb1cc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Cdk9 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Txndc5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn2b Rnf20 ortho G G G G G G G G G G G G G G G G G G G G Rnf20 Ushbp1 ortho G G G G G G G G G G G G Gba Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Plekho2 ortho GP G G G G G G G G G G G G G G G G G G G G G G H2afx Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Xaa-Pro aminopeptidase 1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2e1 Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Slain2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Paf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Xrcc3 ortho Sirt6 Rnf20 ortho Ar Rnf20 ortho G G G G G G G G G G G G G G G G Rnf40 Rnf20 ortho P Rnf20 Uchl5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fgfr4 Rnf20 ortho G G G G G Ube2b Rnf20 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Bag4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Rnf20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf20 Supt6h ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smurf2 Rnf20 ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P56720 Q5DTM8 affinity chromatography technology 24425205 physical association X 2 P56720 Q5DTM8 pull down 24425205 direct interaction X 2 P56720 Q5DTM8 affinity chromatography technology 24425205 physical association X 2 Q5DTM8 Q91WA6 affinity chromatography technology 21829440 physical association X 2 Q5DTM8 Q9WTN3 affinity chromatography technology 24425205 physical association X 2 Q5DTM8 Q9WTN3 affinity chromatography technology 24425205 physical association X 2 Q5DTM8 P34056 affinity chromatography technology 24374663 physical association X 2 Q5DTM8 P34056 affinity chromatography technology 24374663 physical association X 2 Q5DTM8 P34056 imaging technique 24374663 colocalization X 2 Q5DTM8 cosedimentation 16615898 colocalization C 1216

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Rnf20 Sharpin MI:0004(affinity chromatography technology) 21829440 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_321371 prey bait Tfap2a Rnf20 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 24374663 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0403(colocalization)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_331755|BIOGRID_331757|BIOGRID_331756 bait|prey|prey prey|bait|bait

PPI - HINT Gene A Gene B PMID Method Quality YWHAE RNF20 16615898 0027 LC RNF20 PGLS 16615898 0027 LC MEN1 RNF20 25591470 0004 LC TFAP2A RNF20 24374663,24374663 0004,0428 LC RNF20 SHARPIN 21829440 0004 LC RNF20 SREBF1 24425205 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9WTN3 Q5DTM8 SREBF1 RNF20 0.376 24425205 Q5DTM8 P62259 RNF20 YWHAE 0.081 16615898 Q5DTM8 O88559 RNF20 MEN1 0.21 25591470 Q5DTM8 P56720 RNF20 SREBF1 0.454 24425205 Q91WA6 Q5DTM8 SHARPIN RNF20 0.21 21829440 Q9CQ60 Q5DTM8 PGLS RNF20 0.081 16615898 Q5DTM8 P34056 RNF20 TFAP2A 0.454 24374663