PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Sin3b Rnf220 20170641 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2e3 Rnf220 20170641 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2e1 Rnf220 20170641 intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Csnk2a1 Rnf220 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf220 Gopc ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf220 Ube2e2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Exoc5 Rnf220 ortho Ap2m1 Rnf220 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ctnnb1 Rnf220 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf220 Hibch ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Csnk2b Rnf220 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Zc4h2 Rnf220 ortho Rnf220 Ube2w ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf220 Pacsin2 ortho Ube2d3 Rnf220 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf220 Gsk3b ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp7 Rnf220 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf220 Tmem214 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6PDX6 Q62141-3 two hybrid 20170641 direct interaction X 2 Q6PDX6 enzymatic study 20170641 ubiquitination reaction C 4 Q6PDX6 P52482 anti tag coimmunoprecipitation 20170641 physical association X 2 P52483 Q6PDX6 anti tag coimmunoprecipitation 20170641 physical association X 2 Q62141 Q6PDX6 two hybrid 20170641 physical association X 2 Q62141 Q6PDX6 pull down 20170641 physical association X 2 Q62141 Q6PDX6 fluorescence microscopy 20170641 colocalization X 2 Q62141 Q6PDX6 anti tag coimmunoprecipitation 20170641 physical association X 2 Q62141 Q6PDX6 anti tag coimmunoprecipitation 20170641 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6PDX6 Q62141 RNF220 SIN3B 0.74 20170641 Q6PDX6 Q29504 RNF220 UBA1 0.033 20170641 Q6PDX6 P61077 RNF220 UBE2D3 0.033 20170641 Q6PDX6 P0CG47 RNF220 UBB 0.033 20170641 Q6PDX6 P52482 RNF220 UBE2E1 0.21 20170641 Q6PDX6 P52483 RNF220 UBE2E3 0.21 20170641