PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Hsd3b7 Eif3i 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif4b Eif3i 16541103 mint,intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eed Eif3i 24457600 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lmna Eif3i 21327095 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ncl Eif3i 17473174 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Eif3i 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rptor Eif3i 21045808 intact exp P Lin28a Eif3i 17473174 biogrid exp G G Mtor Eif3i 21045808 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3a Eif3i 17581632 intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif4g1 Eif3i 16541103 innatedb,mint,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3b Eif3i 16541103 innatedb,mint,intact exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dnaja2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prrc2b Eif3i ortho P Mettl18 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G Nedd4l Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif1 Eif3i ortho P Hecw2 Eif3i ortho Ndufb5 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Snw1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ran Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cnbp Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stt3b Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp22 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G Actb Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps13 Eif3i ortho P G G G G G G G G G G G G Exosc6 Eif3i ortho Sin3a Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ybx1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl37a Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Polyadenylate-binding protein, PABP Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3f Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3i Epb41l1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Clec4g Eif3i ortho G G G G Mcc Eif3i ortho Eif3h Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lyar Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubr5 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Npm1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk18 Eif3i ortho G G G G G G G G G G G G G G G G E2f5 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Polr1c Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3e Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kat2b Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Icam1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G Tgfbr2 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tardbp Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gtf2b Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sub1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdcd4 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cul3 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prpf40b Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G Dnaja4 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif2b5 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kif11 Eif3i ortho G G G G G G G G G G Ppp2ca Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl27a Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arrb1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Esr1 Eif3i ortho G G G G G Tra2b Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Tnfrsf14, Tumor necrosis factor receptor superfamily member 14 Eif3i ortho Chek1 Eif3i ortho G G G G G G G G G G G G G G G Eif1b Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dcaf10 Eif3i ortho Slc3a2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc5l Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3k Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Arf6 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif2s1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Eif3i ortho Traf6 Eif3i ortho G G G G G G G G G G G G G G G G G G G G Eif3i Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tfe3 Eif3i ortho Igsf8 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ccna1 Eif3i ortho G Lman1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nars Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3i Pfkp ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tgfb1 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G Xpo1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdc123 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tada2a Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rad21 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sfn Eif3i ortho P G G G G G G G G Trip12 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atg2a Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Numa1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pin1 Eif3i ortho P Bms1l Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl23a Eif3i ortho P Setd2 Eif3i ortho Abce1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myc Eif3i ortho G G G G G G G G G G G G G G G G G G G G G Vcam1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Itga4 Eif3i ortho G G G G Sirt7 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3l Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif6 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wipi2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3d Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3c Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps20 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Srsf6 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pak2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Taf9 Eif3i ortho Ero1l Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3i Eif3g ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Copg2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3i Myo1c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3i Sgk1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd81 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp3 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Taf5 Eif3i ortho Rpl10 Eif3i ortho P Eif5 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3i Eif2s3y ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Srsf7 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cpne8 Eif3i ortho Pan2 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sparcl1 Eif3i ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ddx3x Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eif3m Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rps5 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lig4 Eif3i ortho Cd4 Eif3i ortho G G Copb2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Herc2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myl9 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Etf1 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk2 Eif3i ortho GP G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants P09405 Q9QZD9 affinity chromatography technology 17473174 physical association X 2 Q9QZD9 Q8K3Y3 affinity chromatography technology 17473174 physical association X 2 Q9QZD9 Q921E6 affinity chromatography technology 24457600 physical association X 2 Q9QZD9 P48678 affinity chromatography technology 21327095 physical association X 2 P10687 Q9QZD9 affinity chromatography technology 23665500 physical association X 2 Q9QZD9 cosedimentation 16615898 colocalization C 1216 Q9QZD9 anti bait coimmunoprecipitation 21045808 association C 3 Q9QZD9 anti bait coimmunoprecipitation 21045808 association C 3 Q9QZD9 pull down 17581632 association C 10 Q9QZD9 pull down 17581632 association C 10 Q9QZD9 molecular sieving 17581632 association C 10 Q8BGD9 Q9QZD9 anti bait coimmunoprecipitation 16541103 physical association X 2 Q6NZJ6 Q9QZD9 anti bait coimmunoprecipitation 16541103 physical association X 2 Q6NZJ6 Q9QZD9 anti bait coimmunoprecipitation 16541103 physical association X 2 Q6NZJ6 Q9QZD9 anti bait coimmunoprecipitation 16541103 physical association X 2 Q8JZQ9 Q9QZD9 anti bait coimmunoprecipitation 16541103 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q9QZD9 P62259 EIF3I YWHAE 0.081 16615898 Q9QZD9 Q8BGD9 EIF3I EIF4B 0.21 16541103 Q9QZD9 P10687 EIF3I PLCB1 0.126 23665500 Q9QZD9 O00257 EIF3I CBX4 0.236 26496610 Q9QZD9 O00303 EIF3I EIF3F 0.236 26496610 Q9QZD9 O15371 EIF3I EIF3D 0.236 26496610 Q9QZD9 O15372 EIF3I EIF3H 0.236 26496610 Q9QZD9 O75821 EIF3I EIF3G 0.236 26496610 Q9QZD9 O75822 EIF3I EIF3J 0.236 26496610 Q9QZD9 P06756 EIF3I ITGAV 0.236 26496610 Q9QZD9 P09874 EIF3I PARP1 0.236 26496610 Q9QZD9 P11388 EIF3I TOP2A 0.236 26496610 Q9QZD9 P14866 EIF3I HNRNPL 0.236 26496610 Q9QZD9 P23396 EIF3I RPS3 0.236 26496610 Q9QZD9 P35251 EIF3I RFC1 0.236 26496610 Q9QZD9 P40937 EIF3I RFC5 0.236 26496610 Q9QZD9 P50990 EIF3I CCT8 0.236 26496610 Q9QZD9 P52701 EIF3I MSH6 0.236 26496610 Q9QZD9 P55884 EIF3I EIF3B 0.236 26496610 Q9QZD9 P60228 EIF3I EIF3E 0.236 26496610 Q9QZD9 P62244 EIF3I RPS15A 0.236 26496610 Q9QZD9 P62249 EIF3I RPS16 0.236 26496610 Q9QZD9 P62304 EIF3I SNRPE 0.236 26496610 Q9QZD9 P62750 EIF3I RPL23A 0.236 26496610 Q9QZD9 P62753 EIF3I RPS6 0.236 26496610 Q9QZD9 P78344 EIF3I EIF4G2 0.236 26496610 Q9QZD9 Q14152 EIF3I EIF3A 0.236 26496610 Q9QZD9 Q15397 EIF3I KIAA0020 0.236 26496610 Q9QZD9 Q1KMD3 EIF3I HNRNPUL2 0.236 26496610 Q9QZD9 Q5JSZ5 EIF3I PRRC2B 0.236 26496610 Q9QZD9 Q5JTH9 EIF3I RRP12 0.236 26496610 Q9QZD9 Q71DI3 EIF3I HIST2H3D 0.236 26496610 Q9QZD9 Q7L2E3 EIF3I DHX30 0.236 26496610 Q9QZD9 Q7L2H7 EIF3I EIF3M 0.236 26496610 Q9QZD9 Q86XZ4 EIF3I SPATS2 0.236 26496610 Q9QZD9 Q8IZL8 EIF3I PELP1 0.236 26496610 Q9QZD9 Q8NHQ9 EIF3I DDX55 0.236 26496610 Q9QZD9 Q92522 EIF3I H1FX 0.236 26496610 Q9QZD9 Q96DV4 EIF3I MRPL38 0.236 26496610 Q9QZD9 Q99613 EIF3I EIF3C 0.236 26496610 Q9QZD9 Q9BV38 EIF3I WDR18 0.236 26496610 Q9QZD9 Q9BVP2 EIF3I GNL3 0.236 26496610 Q9QZD9 Q9H0S4 EIF3I DDX47 0.236 26496610 Q9QZD9 Q9H967 EIF3I WDR76 0.236 26496610 Q9QZD9 Q9NRW3 EIF3I APOBEC3C 0.236 26496610 Q9QZD9 Q9NXF1 EIF3I TEX10 0.236 26496610 Q9UBQ5 Q9QZD9 EIF3K EIF3I 0.236 26496610 Q9Y262 Q9QZD9 EIF3L EIF3I 0.236 26496610 Q9Y2P8 Q9QZD9 RCL1 EIF3I 0.236 26496610 Q9Y3F4 Q9QZD9 STRAP EIF3I 0.236 26496610 Q9Y520 Q9QZD9 PRRC2C EIF3I 0.236 26496610 Q9Y5B9 Q9QZD9 SUPT16H EIF3I 0.236 26496610 Q9Y5J1 Q9QZD9 UTP18 EIF3I 0.236 26496610 Q9QZD9 P23116 EIF3I EIF3A 0.376 17581632 Q9QZD9 Q921E6 EIF3I EED 0.126 24457600 Q9QZD9 Q9EQC1 EIF3I HSD3B7 0.081 16615898 Q9QZD9 Q9QWF0 EIF3I CHAF1A 0.126 26365490 Q9QZD9 Q8K4Q0 EIF3I RPTOR 0.236 21045808 Q9QZD9 P09405 EIF3I NCL 0.21 17473174 Q9QZD9 Q8K3Y3 EIF3I LIN28A 0.21 17473174 Q9QZD9 Q6NZJ6 EIF3I EIF4G1 0.376 16541103 Q9QZD9 Q8JZQ9 EIF3I EIF3B 0.21 16541103 Q9QZD9 Q9JLN9 EIF3I MTOR 0.126 21045808 Q9QZD9 P48678 EIF3I LMNA 0.21 21327095