PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Pou5f1 Trim24 20362542 biogrid,intact exp Ywhae Trim24 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Sertad1 11331592 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Trim24 10562550 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pgr Trim24 8978696 intact exp, ortho G Trim28 Trim24 21531907 dip exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tp53 Trim24 19556538 dip exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rxra Trim24 7744009,8978696 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cbx3 Trim24 10562550 biogrid exp, ortho G G G G Esr1 Trim24 8978696 intact exp, ortho G G G G G Vdr Trim24 8978696 intact exp, ortho G G G G G G G G G G G Cbx5 Trim24 10562550,8978696 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cbx1 Trim24 10562550,8978696 biogrid,intact exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Trim33 21531907 dip exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rara Trim24 8978696 intact exp, ortho G G Sumo1 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Foxi1 ortho G G G G Hnf4a Trim24 ortho G G G G G G G G G G G Trim24 Trim8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brca1 Trim24 ortho G G G G G G G G G G G G G Cdk12 Trim24 ortho G G G G G G G G G G G G G G Ncoa1 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Rnf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspb1 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Brd7 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hdac1 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Nr3c2 ortho Trim24 Sf3b1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Rnf181 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pml Trim24 ortho G G G G G G G G G G G G G G G G G G G G G Thra Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Magea10 Trim24 ortho Trim24 Gtf2e1 ortho Nr2f2 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Flna ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat6 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h4a, Hist1h4b, Hist1h4c, Hist1h4d, Hist1h4f, Hist1h4h, Hist1h4i, Hist1h4j, Hist1h4k, Hist1h4m, Hist2h4a, Hist4h4 Trim24 ortho G G G G G G G G G G G G G G Pparg Trim24 ortho G G G G G G G G G G G G G G G Tcf4 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Trim24 ortho G G G G Trim24 Qprt ortho G G G Esr2 Trim24 ortho G Nr3c1 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fosl1 Trim24 ortho G Ar Trim24 ortho G G G G G G G G G G G G G G G G Hdac2 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Sf3b2, Splicing factor 3b, subunit 2 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Rnf141 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atf4 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Trim24 ortho Ube2u Trim24 ortho Trim24 Taf11 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Nono ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Cbx8 ortho G G G G G G G G G G G Nfe2l2 Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trim24 Taf7 ortho G G G G G G G G G G G G G G G G G G Trim24 Taf1c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Taf1b Trim24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q13263 Q64127 two hybrid 10022127 direct interaction X 2 Q64127 affinity chromatography technology 20362542 physical association X 2 P28700 Q64127 two hybrid 7744009 direct interaction X 2 P28700 Q64127 affinity chromatography technology 7744009 physical association X 2 Q9JL10 Q64127 two hybrid 11331592 direct interaction X 2 Q64127 P83917 enzymatic study 10562550 direct interaction X 2 Q64127 Q64127 enzymatic study 10562550 direct interaction X 2 Q64127 Q9UPN9-2 two hybrid 10022127 direct interaction X 2 Q64127 P83917 affinity chromatography technology 8978696 physical association X 2 Q9DCC5 Q64127 enzymatic study 10562550 direct interaction X 2 Q9DCC5 Q64127 affinity chromatography technology 10562550 physical association X 2 Q61686 Q64127 enzymatic study 10562550 direct interaction X 2 Q61686 Q64127 affinity chromatography technology 8978696 physical association X 2 Q64127 two hybrid 10022127 direct interaction X 2 P21506 Q64127 two hybrid 10022127 direct interaction X 2 Q64127 tandem affinity purification 19556538 - C 4 Q64127 anti bait coimmunoprecipitation 21531907 - C 3 Q64127 Q99PP7 anti bait coimmunoprecipitation 21531907 physical association X 2 Q64127 Q99PP7 anti bait coimmunoprecipitation 21531907 physical association X 2 Q64127 Q549C9 anti bait coimmunoprecipitation 19556538 physical association X 2 Q64127 Q549C9 tandem affinity purification 19556538 physical association X 2 Q62318 Q64127 anti bait coimmunoprecipitation 21531907 physical association X 2 Q64127 tandem affinity purification 20362542 association C 94 P28700 Q64127 two hybrid 8978696 physical association X 2 Q64127 P83917 two hybrid 8978696 physical association X 2 Q64127 P19785 two hybrid 8978696 physical association X 2 Q64127 Q00175 two hybrid 8978696 physical association X 2 Q64127 P83917 two hybrid 8978696 physical association X 2 Q64127 P83917 pull down 8978696 physical association X 2 Q64127 P83917 two hybrid 8978696 physical association X 2 P11416 Q64127 two hybrid 8978696 physical association X 2 P48281 Q64127 two hybrid 8978696 physical association X 2 Q61686 Q64127 two hybrid 8978696 physical association X 2 Q61686 Q64127 two hybrid 8978696 physical association X 2 Q61686 Q64127 pull down 8978696 physical association X 2 Q61686 Q64127 two hybrid 8978696 physical association X 2 P21506 Q64127 two hybrid 9016654 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Pgr Trim24 MI:0018(two hybrid) 8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_176910 prey bait Pou5f1 Trim24 MI:0676(tandem affinity purification)|MI:0004(affinity chromatography technology) 20362542 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0914(association)|MI:0915(physical association) (intact)|(biogrid) UniProt_170860|BIOGRID_314435 prey|bait prey|prey Vdr Trim24 MI:0018(two hybrid) 8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_176909 prey bait Rxra Trim24 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 7744009,8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid)|(intact) BIOGRID_329027|BIOGRID_329028|UniProt_176906 bait|bait|prey prey|prey|bait Cbx1 Trim24 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid)|MI:0415(enzymatic study)|MI:0018(two hybrid)|MI:0027(cosedimentation) 10562550,16615898,8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization) (intact)|(intact)|(biogrid)|(intact)|(biogrid)|(intact)|(intact) UniProt_176914|UniProt_176912|BIOGRID_325586|UniProt_176905|BIOGRID_322458|UniProt_176901|UniProt_167129 bait|prey|bait|prey|prey|prey|neutral component prey|bait|prey|bait|bait|bait|neutral component Cbx3 Trim24 MI:0415(enzymatic study)|MI:0415(enzymatic study)|MI:0027(cosedimentation) 10562550,16615898 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0915(physical association)|MI:0403(colocalization) (biogrid)|(biogrid)|(intact) BIOGRID_322459|BIOGRID_322461|UniProt_167129 prey|bait|neutral component bait|prey|neutral component Trim24 Sertad1 MI:0018(two hybrid) 11331592 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_325377 bait prey Rara Trim24 MI:0018(two hybrid) 8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_176907 prey bait Esr1 Trim24 MI:0018(two hybrid) 8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_176908 prey bait Cbx5 Trim24 MI:0018(two hybrid)|MI:0415(enzymatic study)|MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0004(affinity chromatography technology)|MI:0018(two hybrid) 10562550,8978696 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association)|MI:0915(physical association) (intact)|(biogrid)|(intact)|(intact)|(biogrid)|(intact) UniProt_176904|BIOGRID_322457|UniProt_176902|UniProt_176911|BIOGRID_325585|UniProt_176913 prey|prey|prey|prey|bait|bait bait|bait|bait|bait|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality RARA TRIM24 8978696 0018 LC ESR1 TRIM24 8978696 0018 LC CBX3 TRIM24 10562550,10562550 0415,0096 LC RXRA TRIM24 8978696,7744009,7744009 0018,0018,0004 LC VDR TRIM24 8978696 0018 LC YWHAE TRIM24 16615898 0027 LC CBX1 TRIM24 10562550,8978696,8978696,10562550,8978696 0096,0018,0004,0415,0096 LC PGR TRIM24 8978696 0018 LC CBX5 TRIM24 10562550,8978696,8978696,10562550,8978696 0096,0018,0004,0415,0096 LC TRIM24 TRIM24 10562550 0415 LC TRIM24 SERTAD1 11331592 0018 LC TP53 TRIM24 19556538,19556538 0676,0006 LC POU5F1 TRIM24 20362542,20362542 0676,0004 LC CBX3 TRIM24 10562550,10562550 0415,0096 LC RXRA TRIM24 7744009,7744009 0018,0004 LC CBX1 TRIM24 10562550,8978696,8978696,10562550,8978696 0096,0018,0004,0415,0096 LC CBX5 TRIM24 10562550,8978696,8978696,10562550,8978696 0096,0018,0004,0415,0096 LC TRIM28 TRIM24 21531907 0006 LC TRIM24 TRIM33 21531907 0006 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q64127 P62259 TRIM24 YWHAE 0.081 16615898 Q64127 Q00175 TRIM24 PGR 0.309 8978696 Q64127 P48281 TRIM24 VDR 0.309 8978696 Q64127 P03372 TRIM24 ESR1 0.309 10022127 Q64127 P28700 TRIM24 RXRA 0.623 8978696,7744009 Q64127 P21506 TRIM24 ZNF10 0.309 10022127 Q64127 P11416 TRIM24 RARA 0.309 8978696 Q64127 P19785 TRIM24 ESR1 0.309 8978696 Q64127 Q64127 TRIM24 TRIM24 0.332 10562550 Q64127 Q13263 TRIM24 TRIM28 0.309 10022127 Q9JL10 Q64127 SERTAD1 TRIM24 0.309 11331592 Q9UPN9 Q64127 TRIM33 TRIM24 0.309 10022127 Q64127 P20263 TRIM24 POU5F1 0.236 20362542 Q64127 P83917 TRIM24 CBX1 0.858 8978696,10562550 Q64127 Q61686 TRIM24 CBX5 0.794 8978696,10562550