PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Prkar1b Ing4 15102471 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G Ing4 Prkar1a 15102471 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Stat1 Ing4 15102471 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rarb Ing4 20211142 biogrid exp G G G G G G G G G G G G G G Jade1 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ing4 Padi4 ortho G G G G Kat7 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gadd45a Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ep300 Ing4 ortho Trim56 Ing4 ortho Ing4 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ing4 Cdc34 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ing4 H2afj ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Suv39h1 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Meaf6 Ing4 ortho Hist1h3b, Hist1h3c, Hist1h3d, Hist1h3e, Hist1h3f, Hist2h3b, Hist2h3c1, Hist2h3c2 Ing4 ortho G G G G Msx1 Ing4 ortho G G G G G G G G G G G G G G G G G G G Hist1h2bm Ing4 ortho Protein Brpf1 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ing4 Egln1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ing4 Mapk8ip2 ortho G G G G G G G G G G Ing4 Hist1h2af ortho Hoxb9 Ing4 ortho G G G G Ing4 Protein Nav2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Kmt2a Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jade2 Ing4 ortho Ppfia1 protein, Protein Ppfia1 Ing4 ortho Ube2d2 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tlx3 Ing4 ortho G Protein Brd1 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pogz Ing4 ortho Becn1 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpp38 Ing4 ortho Hnrnpd Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jade3 Ing4 ortho Tp53 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ing4 Ebna1bp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myc Ing4 ortho G G G G G G G G G G G G G G G G G G G G G Rela Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn2a Ing4 ortho G3bp2 Ing4 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Stat1 Ing4 MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_162684 bait null Ing4 Prkar1a MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_165026 null bait Prkar1b Ing4 MI:0018(two hybrid) 15102471 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (intact) UniProt_165055 bait null Rarb Ing4 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313694 prey bait

PPI - HINT Gene A Gene B PMID Method Quality PRKAR1B ING4 15102471 0018 LC RARB ING4 20211142 0018 HT STAT1 ING4 15102471 0018 LC ING4 PRKAR1A 15102471 0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8C0D7 P12849 ING4 PRKAR1B 0.183 15102471 Q8C0D7 P22605 ING4 RARB 0.183 20211142 Q8C0D7 P42225 ING4 STAT1 0.183 15102471 Q9DBC7 Q8C0D7 PRKAR1A ING4 0.183 15102471