PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Trim30a Tab3 18345001 innatedb exp G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Map3k7 17384642,19955178 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Uba52 Tab3 19927120 mint,intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Becn1 Tab3 21976705 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Tab3 19136968 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Pin1 ortho Tab3 Rbck1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Tab3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Tab1 ortho G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Atg5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Tab2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ybx1 Tab3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf6 Tab3 ortho G G G G G G G G G G G G G G G G G G G G Tab3 Atg13 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Cep57l1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Tlr3 ortho G G G G G G G G G G G G G G G G G G G G G G G Ikbkg Tab3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Traf2 Tab3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G Tab3 Wdr34 ortho Tab3 Protein Trim38 ortho Smad7 Tab3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q571K4 affinity chromatography technology 17384642 physical association X 2 Q571K4 P0CG50 pull down 19136968 direct interaction X 2 Q571K4 affinity chromatography technology 19955178 physical association X 2 Q571K4 O88597 two hybrid 21976705 direct interaction X 2 Q571K4 P62984 pull down 19927120 direct interaction X 2 Q571K4 P62984 x-ray crystallography 19927120 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ubc Tab3 MI:0004(affinity chromatography technology) 19136968 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_316549 prey bait Becn1 Tab3 MI:0004(affinity chromatography technology) 21976705 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_323118 prey bait Ubb Tab3 MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography)|MI:0114(x-ray crystallography) 19927120 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction)|MI:0407(direct interaction) (intact)|(intact)|MI:0471(mint)|MI:0471(mint)|(intact) UniProt_206611|UniProt_171645|MINT_76014|MINT_76013|UniProt_171644 prey|prey|prey|neutral component|neutral component bait|bait|bait|neutral component|neutral component Tab3 Map3k7 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 17384642,19955178 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_316602|BIOGRID_322496 prey|prey bait|bait

PPI - HINT Gene A Gene B PMID Method Quality BECN1 TAB3 21976705 0018 LC UBC TAB3 19927120,19927120 0114,0096 LC UBA52 TAB3 19927120,19927120 0114,0096 LC UBC TAB3 19136968,19927120,19927120 0096,0114,0096 LC UBA52 TAB3 19927120,19927120 0114,0096 LC TRAF6 TAB3 26474655 0004 LC TAB3 MAP3K7 19955178,19955178,17384642 0004,0007,0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q571K4 O88597 TAB3 BECN1 0.309 21976705 Q571K4 P0CG50 TAB3 UBC 0.309 19136968 Q571K4 P62991 TAB3 UBA52 0.523 19927120 Q62073 Q571K4 MAP3K7 TAB3 0.376 19955178,17384642 Q571K4 P9WIA1 TAB3 PTPA 0.309 25642820 Q571K4 P70196 TAB3 TRAF6 0.21 26474655