PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Cul4a Dtl ortho G G G G G G G G G G G Dtl Atr ortho G G G G G G G G G G G Cftr Dtl ortho G G G G G Dtl Fbxo18 ortho G G G G G G G G G G G Dtl Cops7a ortho G G G G G G G G G G G Dtl Ywhab ortho G G G G G G G G G G G Dtl Rad18 ortho G G G G G Ywhah Dtl ortho G G G G G G G G G G G Tp53 Dtl ortho G G G G G G G G G G G Cops4 Dtl ortho G G G G G G G G G G G Dtl Grwd1 ortho G G G G G G G G G G G Dtl Fbxo11 ortho G G G G G G G G G G G Aurkb Dtl ortho G G G G G G G G G G Ywhae Dtl ortho G G G G G G G G G G G Msh2 Dtl ortho G G G G G G G G G G G Cdkn1a Dtl ortho G G G G G G G G G G G Mdm2 Dtl ortho G G G G G G G G G G G Ube2d1 Dtl ortho G G G G G G G G G G G Cul4b Dtl ortho G G G G G G G G G G G Dtl Hltf ortho G G G G G G G G G G Chek1 Dtl ortho G G G G G G G G G Msh6 Dtl ortho G G G G G G G G G G G Lyn Dtl ortho Wdr5 Dtl ortho G G G G G G G G G G G Ube2n Dtl ortho Ercc5 Dtl ortho G G G G G G G G G G Dtl Ddb1 ortho G G G G G G G G G G G Dtl Tceal1 ortho G G G G G G G Dtl Kat2a ortho G G G G G G G G G G G Ywhaz Dtl ortho G G G G G G G G G G G Dtl Tob1 ortho G G G G G G G G G G G Cops3 Dtl ortho G G G G G G G G G G G Dtl Shprh ortho G G G G G G G G G G G Tubg1 Dtl ortho G G G G G G G G G G G Dtl Dda1 ortho G G G G G G G G G G G Setd8 Dtl ortho G G G G G G G G G G G Dtl UPF0586 protein C9orf41 homolog ortho Ywhag Dtl ortho G G G G G G G G G G G Ube2i Dtl ortho G G G G G G G G G G G Cops6 Dtl ortho G G G G G G G G G G G Dtl Cdt1 ortho G G G G G G G G G G Sfn Dtl ortho G G G G Pcna Dtl ortho G G G G G G G G G G G Cops5 Dtl ortho G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q3TLR7 A0A0A0MR05 affinity chromatography technology 18235224 physical association X 2 Q3TLR7 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 B2RBV7 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 Q16531 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 Q13620-3 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 Q9BT78 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 Q8N122-2 affinity chromatography technology 18235224 physical association X 2 Q3TLR7 P61201-2 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 Q7L5N1 affinity chromatography technology 20360068 physical association X 2 Q3TLR7 tandem affinity purification 20360068 physical association C 8

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q3TLR7 P12004 DTL PCNA 0.236 26496610 Q3TLR7 O75150 DTL RNF40 0.236 26496610 Q3TLR7 O15078 DTL CEP290 0.236 26496610 Q3TLR7 A1L170 DTL C1ORF226 0.236 26496610 Q3TLR7 P50990 DTL CCT8 0.236 26496610 Q3TLR7 P17987 DTL TCP1 0.236 26496610 Q3TLR7 P49368 DTL CCT3 0.236 26496610 Q3TLR7 P40227 DTL CCT6A 0.236 26496610 Q3TLR7 P48643 DTL CCT5 0.236 26496610 Q3TLR7 P62877 DTL RBX1 0.236 26496610 Q3TLR7 P50991 DTL CCT4 0.236 26496610 Q3TLR7 P78371 DTL CCT2 0.236 26496610 Q99832 Q3TLR7 CCT7 DTL 0.236 26496610 Q92905 Q3TLR7 COPS5 DTL 0.236 26496610 Q96EB6 Q3TLR7 SIRT1 DTL 0.236 26496610 Q9UNS2 Q3TLR7 COPS3 DTL 0.236 26496610 Q9C0J8 Q3TLR7 WDR33 DTL 0.236 26496610 Q9BW61 Q3TLR7 DDA1 DTL 0.236 26496610 Q9UBW8 Q3TLR7 COPS7A DTL 0.236 26496610 Q9NP92 Q3TLR7 MRPS30 DTL 0.236 26496610 Q9NZJ0 Q3TLR7 DTL DTL 0.236 20360068 Q7L5N1 Q3TLR7 COPS6 DTL 0.332 20360068,26496610 Q3TLR7 Q13620 DTL CUL4B 0.416 26496610,20360068 Q3TLR7 Q13619 DTL CUL4A 0.416 26496610,20360068 Q3TLR7 P61201 DTL COPS2 0.416 26496610,20360068 Q9BT78 Q3TLR7 COPS4 DTL 0.416 26496610,20360068 Q3TLR7 Q16531 DTL DDB1 0.416 26496610,20360068 Q3TLR7 B4DSW0 DTL B4DSW0 0.126 26496610 Q3TLR7 C9JFE4 DTL C9JFE4 0.126 26496610 Q3TLR7 E7EM64 DTL COPS6 {ECO:0000313|ENSEMBL:ENSP00000400617} 0.126 26496610 Q3TLR7 E9PGT6 DTL COPS8 {ECO:0000313|ENSEMBL:ENSP00000387212} 0.126 26496610 Q3TLR7 Q13098 DTL GPS1 0.126 26496610 Q8N122 Q3TLR7 RPTOR DTL 0.21 18235224 Q8N3X6 Q3TLR7 LCORL DTL 0.126 26496610 Q99627 Q3TLR7 COPS8 DTL 0.126 26496610 Q9BVC4 Q3TLR7 MLST8 DTL 0.21 18235224