PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Runx2 Satb2 16751105 biogrid exp G G G Atf4 Satb2 16751105 biogrid exp G G G G G G G G G G Ski Satb2 22334647 biogrid,dip exp G G G G G G G G G G Tfcp2l1 Satb2 20362541 biogrid,intact exp G G G G G Satb2 Mta2 22334647 biogrid,dip exp, ortho G G G G G G G G G G Hdac1 Satb2 22334647 biogrid,dip exp, ortho G G G G G G G G G G Foxa3 Satb2 ortho G G G G Foxc2 Satb2 ortho G Foxc1 Satb2 ortho G Jun Satb2 ortho G G G G G G G G G G Foxl1 Satb2 ortho Klhl20 Satb2 ortho Foxg1 Satb2 ortho G G G Satb2 Foxp3 ortho Tead2 Satb2 ortho G Rbpj Satb2 ortho G G G G G G G G G G Foxd3 Satb2 ortho Foxs1 Satb2 ortho Foxa2 Satb2 ortho G G G G G Elavl1 Satb2 ortho G G G G G G G G G G Satb2 Foxj2 ortho G G G G G G G G G G Satb2 Aim2 ortho Foxn1 Satb2 ortho Foxb1 Satb2 ortho Satb2 Dpy30 ortho G G G G G G G G G G Rab3il1 Satb2 ortho G G Satb2 Lhx6 ortho G G G Satb2 Foxo1 ortho G G G G G G G G G G Foxe1 Satb2 ortho Satb2 Qprt ortho G Foxk2 Satb2 ortho G G G G G G G G G G Foxf1 Satb2 ortho G G G G Foxi2 Satb2 ortho Pias1 Satb2 ortho G G G G G G G G G G Tp63 Satb2 ortho G G Foxa1 Satb2 ortho G G G G Protein Magea10 Satb2 ortho Foxq1 Satb2 ortho G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8VI24 Q9R190 affinity chromatography technology 22334647 physical association X 2 Q3UNW5 Q8VI24 affinity chromatography technology 20362541 physical association X 2 Q8VI24 affinity chromatography technology 22334647 physical association X 2 Q8VI24 affinity chromatography technology 22334647 physical association X 2 Q8VI24 Q06507 affinity chromatography technology 16751105 physical association X 2 Q8VI24 Q08775-9 affinity chromatography technology 16751105 physical association X 2 Q8VI24 Q06507 affinity chromatography technology 16751105 physical association X 2 O09106 Q8VI24 affinity chromatography technology 22334647 physical association X 2 Q60698 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 Q60698 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 Q60698 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 P12755 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 P12755 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 O09106 Q8VI24 anti bait coimmunoprecipitation 22334647 physical association X 2 Q8VI24 anti tag coimmunoprecipitation 20362541 association C 93

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Atf4 Satb2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 16751105 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_325449|BIOGRID_325447 bait|prey prey|bait Satb2 Mta2 MI:0004(affinity chromatography technology) 22334647 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_320713 prey bait Runx2 Satb2 MI:0004(affinity chromatography technology) 16751105 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325448 prey bait Hdac1 Satb2 MI:0004(affinity chromatography technology) 22334647 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_320712 bait prey Ski Satb2 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 22334647 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_320711|BIOGRID_320710 prey|bait bait|prey Tfcp2l1 Satb2 MI:0004(affinity chromatography technology)|MI:0007(anti tag coimmunoprecipitation)|MI:0007(anti tag coimmunoprecipitation) 20362541 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0914(association)|MI:0914(association) (biogrid)|(intact)|(intact) BIOGRID_314067|UniProt_170696|UniProt_107197 bait|bait|bait prey|prey|prey

PPI - HINT Gene A Gene B PMID Method Quality HDAC1 SATB2 22334647,22334647 0004,0006 LC ATF4 SATB2 16751105 0004 LC RUNX2 SATB2 16751105 0004 LC TFCP2L1 SATB2 20362541,20362541 0004,0007 LC SKI SATB2 22334647,22334647 0004,0006 LC SATB2 MTA2 22334647,22334647 0004,0006 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8VI24 Q3UNW5 SATB2 TFCP2L1 0.236 20362541 Q8VI24 Q06507 SATB2 ATF4 0.376 16751105 Q8VI24 Q08775 SATB2 RUNX2 0.21 16751105 Q9R190 Q8VI24 MTA2 SATB2 0.21 22334647 Q8VI24 O09106 SATB2 HDAC1 0.21 22334647