PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhah Ube3c 21311561 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Eed 24457600 biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ywhae Ube3c 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Huwe1 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Pank4 ortho P Psmc5 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Rbm15, RNA binding motif protein 15 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Psmd6 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Utrn Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp13 Ube3c ortho G G G G G G Lrrk2 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G Scn2b Ube3c ortho Elavl1 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Ube2v2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Shfm1 Ube3c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Wdr74 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Wdr92 ortho Rad21 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Eef2k Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Tlk1 ortho Psma2 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Ube3c ortho Ube3c Golga2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2l3 Ube3c ortho P Ube3c BC025105 ortho G G G Ube2d2 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Psmd2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Anxa7 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Myc Ube3c ortho G G G G G G G G G G G G G G G G G G G G G Thoc2 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Mta2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G App Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Efnb2 Ube3c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd14 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d1 Ube3c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kdm1a Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2k Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Ptp4a3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube3c Phka2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Thoc7 Ube3c ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ect2 Ube3c ortho G G G G G G G G G G G G G Cpeb4 Ube3c ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cand2 Ube3c ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q80U95 Q921E6 affinity chromatography technology 24457600 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ube3c Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332497 prey bait

PPI - HINT Gene A Gene B PMID Method Quality YWHAE UBE3C 16615898 0027 LC YWHAH UBE3C 21311561 0030 LC UBE3C EED 24457600 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q80U95 P62259 UBE3C YWHAE 0.081 16615898 Q921E6 Q80U95 EED UBE3C 0.126 24457600 Q80U95 P68510 UBE3C YWHAH 0.126 21311561