PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Asb6 Sertad1 20211142 biogrid exp G G G G G G G G G Ewsr1 Asb6 20211142 biogrid exp G G G G G G G G G Asb6 Sh2b2 15231829 biogrid,i2d exp, ortho G Fgg Asb6 ortho G G G Cul4b Asb6 ortho G G G G G G G G G L3mbtl3 Asb6 ortho App Asb6 ortho G G G G G G G G G Asb6 Rnf7 ortho G G G G G G G G G Fga Asb6 ortho G G Asb6 Cul5 ortho Cops5 Asb6 ortho G G G G G G G G G Asb6 Dcun1d1 ortho G G G G G G G G G Asb6 Mcts1 ortho G G G G G G G G G Hsp90ab1 Asb6 ortho G G G G G G G G G Hdgf Asb6 ortho G G G G G G G G G Hspb1 Asb6 ortho G G G G G G G G G Slc25a5 Asb6 ortho G G G G G G G G G Xaa-Pro aminopeptidase 1 Asb6 ortho G G G G G G G G G Hif1an Asb6 ortho Elavl1 Asb6 ortho G G G G G G G G G Hsp90aa1 Asb6 ortho G G G G G G G G G Tceb1 Asb6 ortho G G G G G G G G G Ezr Asb6 ortho G G G G G G G G G Ogfod1 Asb6 ortho Fgb Asb6 ortho G Fh Asb6 ortho G G G G G G G G G Asb6 Prosc ortho G G G G G G G G G Cadps2 Asb6 ortho G G G G G G G G G Rnf41 Asb6 ortho G G G G G G G G G Asb6 Atic ortho

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q91ZU1 Q9JL10 two hybrid 20211142 direct interaction X 2 Q91ZU1 Q9JID9 two hybrid 15231829 direct interaction X 2 Q91ZU1 Q9JID9 affinity chromatography technology 15231829 physical association X 2 Q91ZU1 Q9JID9 affinity chromatography technology 15231829 physical association X 2 Q91ZU1 Q61545 two hybrid 20211142 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Asb6 Sh2b2 MI:0018(two hybrid)|MI:0018(two hybrid)|MI:0018(two hybrid) 15231829 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0407(direct interaction)|MI:0915(physical association) (biogrid)|(biogrid)|(biogrid) BIOGRID_327846|BIOGRID_327845|BIOGRID_327847 bait|prey|prey prey|bait|bait Asb6 Sertad1 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313712 prey bait Ewsr1 Asb6 MI:0018(two hybrid) 20211142 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) (biogrid) BIOGRID_313074 bait prey

PPI - HINT Gene A Gene B PMID Method Quality EWSR1 ASB6 20211142 0018 HT ASB6 SH2B2 15231829,15231829 0004,0018 LC ASB6 SERTAD1 20211142 0018 HT ASB6 SH2B2 15231829,15231829 0004,0018 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q91ZU1 Q61545 ASB6 EWSR1 0.183 20211142 Q9JL10 Q91ZU1 SERTAD1 ASB6 0.183 20211142 Q9JID9 Q91ZU1 SH2B2 ASB6 0.569 15231829