PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Tbl3 Foxp3 22922362 biogrid exp Ywhae Tbl3 16615898 intact exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Eed 24457600 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cap1 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Ddx52 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Rp2 ortho GP G G G G G G G G G G G G G G G G Tbl3 Cirh1a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bms1l Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Grb7 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G Tbl3 Itsn2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gpi Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Urm1 ortho G G G G G G G G G G G G G G G G G G G G G Atp5a1 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Aatf ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vdac2 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pwp2 Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Lgr4 Tbl3 ortho Tbl3 Rpf2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ntrk1 Tbl3 ortho Tbl3 Rbm19 ortho P G G G G G G G G G G G G G G G G G G G G Tbl3 Gtpbp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rbbp7 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Jun Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nol10 Tbl3 ortho P Tbl3 Noc2l ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Noc3l ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Exosc1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Nol6 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Nop56 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspd1 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Cul7 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Dnaja2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Exosc5 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Dnajb1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Fbl Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa4 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct7 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Imp4 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Utp15 ortho P Wipi2 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Uba1 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Utp11l ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nudc Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Usp11 ortho G G G G G G G G G G G G G G G G G G G G G G Tbl3 Dhx30 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Noc4l Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Nop9 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Ddx24 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mphosph10 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Rrp9 ortho P G G G G G G G G G G G G G G G G G Bysl Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cebpz Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Utp20 Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Hnrnpu ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Appbp2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Cacnb4 ortho G G G G G G G G G Atp6v1b2 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Blmh ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Wdr46 ortho P G G G G G G G Aurkb Tbl3 ortho G G G G G G G G G G G G G Arhgap25 Tbl3 ortho Tbl3 Ddx18 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct8 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Nifk ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp5b Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Nat10 ortho P Tbl3 Ddx56 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cep164 Tbl3 ortho Usp36 Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wdr3 Tbl3 ortho P Polr1b Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Egfr Tbl3 ortho GP G G G G G G G G G G G G G G G G G Coq2 Tbl3 ortho Sfn Tbl3 ortho P G G G G G G G G Kiaa0020 Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp6v1a Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Dlst ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Dnase2b ortho G G Fam43a Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Nr2e3 ortho G Dnajb14 Tbl3 ortho Krr1 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sirt7 Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Wdr36 Tbl3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Dcaf13 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Nop58 Tbl3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Ftsj3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G Tbl3 Ak6 ortho P Tbl3 Dkc1 ortho P Tbl3 Klk11 ortho G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q8C4J7 Q53Z59 affinity chromatography technology 22922362 physical association X 2 Q8C4J7 Q921E6 affinity chromatography technology 24457600 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Tbl3 Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332120 prey bait Tbl3 Foxp3 MI:0004(affinity chromatography technology) 22922362 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_324899 prey bait

PPI - HINT Gene A Gene B PMID Method Quality YWHAE TBL3 16615898 0027 LC TBL3 EED 24457600 0004 LC TBL3 FOXP3 22922362 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q8C4J7 P62259 TBL3 YWHAE 0.081 16615898 Q921E6 Q8C4J7 EED TBL3 0.126 24457600 Q99JB6 Q8C4J7 FOXP3 TBL3 0.126 22922362