PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Usp19 Rnf123 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Flnb 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ubc Rnf123 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Dsg1a 19015242 biogrid exp P Alb Rnf123 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G Hspa1l Rnf123 19015242 biogrid exp P G G G Eef1a1 Rnf123 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Flnc 19015242 biogrid exp GP G G G G G G G G G G Actg1 Rnf123 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Myh9 19015242 biogrid exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdkn1b Rnf123 15531880 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Ubac1 15531880 biogrid exp, ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Ndufa10 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Jak3 ortho G G G G G G G G G G G G G G G Rnf123 Smad2 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Gabarapl1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Gabarap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Deleted in autism protein 1 homolog Rnf123 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Rdh12 ortho G G G G G G G Rnf123 Postmeiotic segregation increased 1 (S. cerevisiae), Protein Pms1 ortho P Rnf123 Chia ortho P G G G G G G G Pnpla1 Rnf123 ortho Rnf123 Tacc3 ortho G G G G G G G G G G Rnf123 Protein Pcdhb22, Protocadherin beta 22 ortho G G Rnf123 Ube2w ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Gabarapl2 Rnf123 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Nxf1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mov10 Rnf123 ortho G G G G G G G G G G G G G G G G G G G G Rnf123 Aldh3b1 ortho G G G G G G G G G G G G G G Gnaz Rnf123 ortho G G G G G G G G G G Rnf123 Zfp277 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Kif21a ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Bves ortho G G G G G G G G G Rnf123 Smad9 ortho Rnf123 Map1lc3b ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rnf123 Plod2 ortho G G G G G G G G G G G G G G G G G G G G G Rnf123 Rad21 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants A1L347 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 Q5XPI3 Q8VHX6 affinity chromatography technology 19015242 physical association X 2 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 P46414 Q5XPI3 affinity chromatography technology 15531880 physical association X 2 P07724 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 Q61495 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 Q8VDD5 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 P10126 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 Q8VDI7 Q5XPI3 affinity chromatography technology 15531880 physical association X 2 Q5XPI3 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 P0CG50 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 P0CG50 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 P63260 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 Q3UJD6-2 Q5XPI3 affinity chromatography technology 19015242 physical association X 2 Q3UJD6-2 Q5XPI3 affinity chromatography technology 19015242 physical association X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Rnf123 Ubac1 MI:0096(pull down) 15531880 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_313891 bait prey Rnf123 Myh9 MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325807 bait prey Hspa1l Rnf123 MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325805 prey bait Rnf123 Flnc MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325803 bait prey Dsg1a Rnf123 MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325808 prey bait Eef1a1 Rnf123 MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325802 prey bait Rnf123 Flnb MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325804 bait prey Ubc Rnf123 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_325799|BIOGRID_325798 prey|prey bait|bait Cdkn1b Rnf123 MI:0096(pull down) 15531880 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_313892 prey bait Alb Rnf123 MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325806 prey bait Usp19 Rnf123 MI:0004(affinity chromatography technology)|MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association)|MI:0915(physical association) (biogrid)|(biogrid) BIOGRID_325810|BIOGRID_325809 bait|prey prey|bait Actg1 Rnf123 MI:0004(affinity chromatography technology) 19015242 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_325801 prey bait

PPI - HINT Gene A Gene B PMID Method Quality ALB RNF123 19015242 0004 LC UBC RNF123 19015242 0004 LC EEF1A1 RNF123 19015242 0004 LC HSPA1L RNF123 19015242 0004 LC CDKN1B RNF123 15531880 0004 LC ACTG1 RNF123 19015242 0004 LC USP19 RNF123 19015242 0004 LC RNF123 DSG1A 19015242 0004 LC RNF123 FLNB 19015242 0004 LC RNF123 MYH9 19015242 0004 LC RNF123 UBAC1 15531880 0004 LC RNF123 FLNC 19015242 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q5XPI3 P07724 RNF123 ALB 0.21 19015242 Q5XPI3 P0CG50 RNF123 UBC 0.21 19015242 Q5XPI3 P10126 RNF123 EEF1A1 0.21 19015242 Q5XPI3 P16627 RNF123 HSPA1L 0.21 19015242 Q5XPI3 P46414 RNF123 CDKN1B 0.21 15531880 Q5XPI3 P63260 RNF123 ACTG1 0.21 19015242 Q61495 Q5XPI3 DSG1A RNF123 0.21 19015242 Q80X90 Q5XPI3 FLNB RNF123 0.21 19015242 Q8VDD5 Q5XPI3 MYH9 RNF123 0.21 19015242 Q8VDI7 Q5XPI3 UBAC1 RNF123 0.21 15531880 Q8VHX6 Q5XPI3 FLNC RNF123 0.21 19015242 Q5XPI3 Q3UJD6 RNF123 USP19 0.376 19015242