PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ywhae Ppp2r2d 16615898 intact exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Supt5h Ppp2r2d 16169070 biogrid exp, ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6a Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Csnk1a1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspd1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Hdac5 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Plekho2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G Atxn2l Ppp2r2d ortho Dapk1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Pbk ortho G G G G G G G G G G G G G G G G G G G G Cct4 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Trrap Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Wipi2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Mea1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Rbm7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Aldh1b1 ortho G G G G G G G G G G Cct5 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Ecsit ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Yars2 Ppp2r2d ortho Wnt3a Ppp2r2d ortho G Slx4 Ppp2r2d ortho Tln2 Ppp2r2d ortho Cct8 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Th Ppp2r2d ortho G G G G G G G Nat10 Ppp2r2d ortho C1qbp Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Bcl2l14 ortho G G G G G G G G G G G G G Leucine carboxyl methyltransferase 1, Leucine carboxyl methyltransferase 1, isoform CRA_b, Protein Lcmt1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Dnaja2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct7 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Bmp15 ortho Gpi Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2cb Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Ccdc130 ortho G P4hb Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Usp7 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa4 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cnbp Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cox6a1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Dmap1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2a Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct3 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Foxs1 Ppp2r2d ortho Hsph1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Pfkp ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Prelp ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk6 Ppp2r2d ortho Ppp2r2d Zcchc8 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Pinx1 ortho G G G G G G G G G G G G G G G G G G G G G Ppp2r1a Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Sertad4 Ppp2r2d ortho Ppp2ca Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tceal1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Ipo7 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppme1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Vps39 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Eif2ak4 ortho G G G G G G G G G G G G G G G G G G G G Jun Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Rpl5 Ppp2r2d ortho Mob1a Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Bag2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Uso1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tcp1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cct6b Ppp2r2d ortho G G Ier2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Smad2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Ssu72 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r1b Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Axin1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp4c Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk16 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Axin2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G Ddhd2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Fam122a ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Aamp Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cdk2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G Polr1b Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G Smad3 Ppp2r2d ortho G G G G G G G G G G G G G G G Foxd3 Ppp2r2d ortho G Gmppb Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Skiv2l2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Unc79 Ppp2r2d ortho Ppp2r2d Ulk2 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Isyna1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Hspa9 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Cse1l ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Kdm5a Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r5a Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ska3 Ppp2r2d ortho Smad1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Psmd1 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Protein Uvrag Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Pdpr Ppp2r2d ortho Snai2 Ppp2r2d ortho G G G G G G G G Wnt10b Ppp2r2d ortho G Ppp2r5c Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Atp6v1b2 Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Fbxl20 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ppp2r2d Mlh1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Prkce Ppp2r2d ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q925E7 affinity chromatography technology 15761153 physical association X 2 Q925E7 affinity chromatography technology 15761153 physical association X 2 O55201 Q925E7 two hybrid 16169070 direct interaction X 2 Q925E7 Q15796-2 affinity chromatography technology 15761153 physical association X 2

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q925E7 P62259 PPP2R2D YWHAE 0.081 16615898 Q925E7 O55201 PPP2R2D SUPT5H 0.183 16169070 Q9HCE7 Q925E7 SMURF1 PPP2R2D 0.126 15761153 Q925E7 P30153 PPP2R2D PPP2R1A 0.236 26496610 Q925E7 P13051 PPP2R2D UNG 0.236 26496610 Q925E7 O43474 PPP2R2D KLF4 0.236 26496610 Q925E7 P67775 PPP2R2D PPP2CA 0.236 26496610 Q925E7 Q6IQ32 PPP2R2D ADNP2 0.236 26496610 Q925E7 P62714 PPP2R2D PPP2CB 0.236 26496610 Q925E7 P63151 PPP2R2D PPP2R2A 0.236 26496610 Q925E7 P30154 PPP2R2D PPP2R1B 0.236 26496610 Q925E7 Q2TBE0 PPP2R2D CWF19L2 0.236 26496610 Q925E7 Q7Z309 PPP2R2D FAM122B 0.236 26496610 Q925E7 Q8IYS2 PPP2R2D KIAA2013 0.236 26496610 Q925E7 Q8N461 PPP2R2D FBXL16 0.236 26496610 Q96E09 Q925E7 FAM122A PPP2R2D 0.236 26496610 Q9UBI6 Q925E7 GNG12 PPP2R2D 0.236 26496610 Q925E7 P84022 PPP2R2D SMAD3 0.126 15761153 Q925E7 Q15796 PPP2R2D SMAD2 0.126 15761153