PTM - CPLM Gene Name UniProt ID Type Position Code Usp14 Q9JMA1 Ubiquitination 14 K Usp14 Q9JMA1 Ubiquitination 49 K Usp14 Q9JMA1 Ubiquitination 62 K Usp14 Q9JMA1 Ubiquitination 64 K Usp14 Q9JMA1 Ubiquitination 130 K Usp14 Q9JMA1 Ubiquitination 214 K Usp14 Q9JMA1 Ubiquitination 238 K Usp14 Q9JMA1 Ubiquitination 291 K Usp14 Q9JMA1 Ubiquitination 300 K Usp14 Q9JMA1 Ubiquitination 313 K Usp14 Q9JMA1 Ubiquitination 342 K Usp14 Q9JMA1 Ubiquitination 448 K Usp14 Q9JMA1 Ubiquitination 453 K

PTM - dbPAF Gene Name UniProt ID Position Type Species Usp14 Q9JMA1 136 Y Mus musculus(Mouse) Usp14 Q9JMA1 143 S Mus musculus(Mouse) Usp14 Q9JMA1 148 S Mus musculus(Mouse) Usp14 Q9JMA1 222 S Mus musculus(Mouse) Usp14 Q9JMA1 226 T Mus musculus(Mouse) Usp14 Q9JMA1 228 S Mus musculus(Mouse) Usp14 Q9JMA1 229 S Mus musculus(Mouse) Usp14 Q9JMA1 230 S Mus musculus(Mouse) Usp14 Q9JMA1 235 T Mus musculus(Mouse) Usp14 Q9JMA1 237 S Mus musculus(Mouse) Usp14 Q9JMA1 369 S Mus musculus(Mouse) Usp14 Q9JMA1 393 S Mus musculus(Mouse) Usp14 Q9JMA1 431 S Mus musculus(Mouse) Usp14 Q9JMA1 52 T Mus musculus(Mouse)

PTM - PhosphositePlus UniProt ID MOD_RSD Type SITE_+/-7_AA Q9JMA1 K54-ac Acetylation MVkGGtLkDDDWGNI Q9JMA1 K62-ac Acetylation DDDWGNIkMkNGMTV Q9JMA1 K448-ac Acetylation RKQDEWIkFDDDkVS Q9JMA1 T52-p Phosphorylation KVMVkGGtLkDDDWG Q9JMA1 S143-p Phosphorylation YAGALRAsGEMAsAQ Q9JMA1 S148-p Phosphorylation RAsGEMAsAQYITAA Q9JMA1 S222-p Phosphorylation LEAIEDDsGREtDSS Q9JMA1 T226-p Phosphorylation EDDsGREtDSSSAPA Q9JMA1 T235-p Phosphorylation SSSAPAVtPSKkKSL Q9JMA1 Y285-p Phosphorylation FINQEVKyLFTGLkL Q9JMA1 S393-p Phosphorylation PNANDKNsPPKEIKY Q9JMA1 S491-p Phosphorylation VEIMEEEsEQ_____ Q9JMA1 K14-ub Ubiquitination TVKWGKEkFEGVELN Q9JMA1 K49-ub Ubiquitination ARQKVMVkGGtLkDD Q9JMA1 K62-ub Ubiquitination DDDWGNIkMkNGMTV Q9JMA1 K64-ub Ubiquitination DWGNIkMkNGMTVLM Q9JMA1 K130-ub Ubiquitination IRSVPELkDALKRYA Q9JMA1 K214-ub Ubiquitination MMRVLQQkLEAIEDD Q9JMA1 K239-ub Ubiquitination PAVtPSKkKSLIDQY Q9JMA1 K291-ub Ubiquitination KyLFTGLkLRLQEEI Q9JMA1 K300-ub Ubiquitination RLQEEITkQSPTLQR Q9JMA1 K313-ub Ubiquitination QRNALYIkSSKISRL Q9JMA1 K342-ub Ubiquitination EKESVNAkVLKDVKF Q9JMA1 K448-ub Ubiquitination RKQDEWIkFDDDkVS Q9JMA1 K453-ub Ubiquitination WIkFDDDkVSIVTPE

PTM - dbPTM UniProt ID Position Code Type Resources References Q9JMA1 136 Y Phosphorylation Swiss-Prot 1010711 17242355 Q9JMA1 143 S Phosphorylation Swiss-Prot 1010711 17242355 Q9JMA1 222 S Phosphorylation Swiss-Prot 1010711 17242355 Q9JMA1 143 S Phosphorylation PhosphoELM.10011 17242355 Q9JMA1 222 S Phosphorylation PhosphoELM.10011 17242355 Q9JMA1 136 Y Phosphorylation PhosphoELM.10011 17242355 Q9JMA1 143 S Phosphorylation Phosphositeplus.1010730 17242355;18846507;20415495;21183079;21659604;21659605 Q9JMA1 148 S Phosphorylation Phosphositeplus.1010730 21183079 Q9JMA1 222 S Phosphorylation Phosphositeplus.1010730 21659605 Q9JMA1 393 S Phosphorylation Phosphositeplus.1010730 19854140;20415495 Q9JMA1 226 T Phosphorylation Phosphositeplus.1010730 17242355;21183079 Q9JMA1 235 T Phosphorylation Phosphositeplus.1010730 21183079 Q9JMA1 52 T Phosphorylation Phosphositeplus.1010730 21183079 Q9JMA1 257 C S-nitrosylation dbSNO 1.0 21278135 Q9JMA1 146 M Oxidation SysPTM 1.1 17242355 Q9JMA1 143 S Phosphorylation SysPTM 1.1 17242355 Q9JMA1 222 S Phosphorylation SysPTM 1.1 17242355 Q9JMA1 136 Y Phosphorylation SysPTM 1.1 17242355

PTM - Phospho.ELM UniProt Position Code PMIDs Kinase Source Type Q9JMA1 136 Y 17242355 HTP Phosphorylation Q9JMA1 222 S 17242355 HTP Phosphorylation Q9JMA1 143 S 17242355 HTP Phosphorylation

PTM - UniProt UniProt ID Position Type PMIDs Q9JMA1 52 Phosphothreonine 21183079 Q9JMA1 143 Phosphoserine 17242355;21183079 Q9JMA1 148 Phosphoserine 21183079

PTM - PHOSIDA Symbol Accession Code Position Surrounding Sequence Type Usp14 IPI00270877 S 143 AGALRApSGEMASA phosphorylation Usp14 IPI00270877 S 148 ASGEMApSAQYITA phosphorylation Usp14 IPI00270877 S 393 NANDKNpSPPKEIK phosphorylation

PTM - mUbiSiDa Gene Name Species Ubiquitination Site Ubiquitination Sequence Evidence PMID Usp14 Mus musculus (Mouse) 453; 448; 62; 64; 14; 238; 130; 214; 49; 342; 300; 313; 291 "453,IKFDDDKVSIVTP; 448,KQDEWIKFDDDKV; 62,DDWGNIKMKNGMT; 64,WGNIKMKNGMTVL; 14,VKWGKEKFEGVEL; 238,PAVTPSKKKSLID; 130,RSVPELKDALKRY; 214,MRVLQQKLEAIED; 49,RQKVMVKGGTLKD; 342,KESVNAKVLKDVK; 300,LQEEITKQSPTLQ; 313,RNALYIKSSKISR; 291,YLFTGLKLRLQEE" 453:22790023; 448:22790023; 62:22790023; 64:22790023; 14:22790023; 238:22790023; 130:22790023; 214:22790023; 49:22790023; 342:22790023; 300:22790023; 313:22790023; 291:22790023