PPI - IID Symbol 1 Symbol 2 PMID DBs Evidence Type Adipose Tissue Adrenal Gland Amygdala Bone Bone Marrow Brain Dorsal Root Ganglia Eye Heart Hindgut Hypothalamus Kidney Liver Lung Lymph Nodes Mammary Gland Midgut Neurons Ovary Pancreas Pituitary Gland Placenta Prostate Salivary Gland Skeletal Muscle Small Intestine Spleen Stomach Testes Uterus Ltn1 Eed 24457600 innatedb,biogrid exp G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Uba52 Ltn1 19196968 dip exp GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Ilkap ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Clspn ortho Ltn1 Spaca1 ortho Kif2a Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Ptp4a3 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Ctdp1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Aldh3a2 Ltn1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Mboat1 ortho G G G G G G G G G G G G G G G G G G Bag1 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Tmem173 Ltn1 ortho G G G G G G G G G G G G G G G G G G G G G Ltn1 Iqcb1 ortho Egfr Ltn1 ortho GP G G G G G G G G G G G G G G G G G Ltn1 Chmp2b ortho P Tap1 Ltn1 ortho P Mapk3 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ube2d2 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Hpx ortho P G G G G G G G G Shfm1 Ltn1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Mms19 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Slamf1 ortho G G G G G G Ltn1 Cep97 ortho Ltn1 Kif18b ortho Ltn1 Prpf19 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G B3galt2 Ltn1 ortho G G G G G Ltn1 Nemf ortho P Ltn1 Uggt1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Rpa1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Tet3 ortho Fen1 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Cd244 Ltn1 ortho G G G Ntrk1 Ltn1 ortho Irf7 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G Dhcr7 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Tirap ortho G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Ccdc93 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ptpn1 Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Rpa3 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Pnpt1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Ca14 ortho G G G G G G G G G G G G G G G Pld3 Ltn1 ortho G G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Npat ortho Ltn1 Xrcc3 ortho Ubc Ltn1 ortho GP G G G G G G G G G G G G G G G G G G G G G G G G G G G G G Ltn1 Pard6b ortho G G G G G G G G G G

PPI - iRefIndex UniProt A UniProt B Method PMID Interaction Type Edge type Num Participants Q6A009 Q921E6 affinity chromatography technology 24457600 physical association X 2 Q6A009 P62984 comigration in sds page 19196968 direct interaction X 2

PPI - PINA Gene A Gene B Method Publications Species A Species B Interaction Type Source Database Interaction Identidiers Experimental Role(s) Interactor A Experimental Role(s) Interactor B Ltn1 Eed MI:0004(affinity chromatography technology) 24457600 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0915(physical association) (biogrid) BIOGRID_332339 prey bait Uba52 Ltn1 MI:0808(comigration in sds page) 19196968 taxid:10090(Mus musculus) taxid:10090(Mus musculus) MI:0407(direct interaction) MI:0465(dip) DIP_846 - -

PPI - HINT Gene A Gene B PMID Method Quality UBC LTN1 19196968 0808 LC UBA52 LTN1 19196968 0808 LC LTN1 EED 24457600 0004 LC

PPI - Mentha Protein A Protein B Gene A Gene B Score PMID Q6A009 P62991 LTN1 UBA52 0.309 19196968 Q921E6 Q6A009 EED LTN1 0.126 24457600